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Management of Two Cases of Spina Bifida and Neonatal Genital Prolapse at the University Hospital of Parakou and Review of the Literature

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Open Journal of Modern Neurosurgery 2022年第4期12卷 216-221页

作者： kouassi jean marie maurin kisito quenum Ayaovi Armel Hadonou Toyifia Eudoxie Bernice quenum Hountondji Sophonie Dokpe Zachée Agbo Matine Balagoun Olatundji Holden Fatigba Service de Neurochirurgie du Centre hospitalo universitaire départemental/Borgou Alibori (CHUD/BA) Parakou Benin Service de chirurgie du Centre hospitalo universitaire départemental/Borgou Alibori (CHUD/BA) Parakou Benin Centre de prise en charge médicale intégrée des nourrissons et femmes enceintes atteints de la drépanocytose (CPMI-NFED) Parakou Benin

Spina bifida, or spinal dysraphism, is a malformative pathology related to an anomaly in the development of the nervous system, occurring during embryogenesis. The neural tube does not close properly around the 28th day of life and affects the development of the spinal column and spinal cord. Spina bifida is characterised by damage to the nervous system and will generate handicaps and damage of varying degrees: neurological motor, sensory, cognitive, genito-phincter (bladder and anorectal) deficits with consequences for the quality of life of these people. The literature describes the association between spinal dysraphism and genital prolapse. However, genital prolapse is an exceptional and rare entity in newborns. We report the observations of two newborns: the first case of a newborn born at term, at 7 days of age, who presented a prolapse of the uterine cervix in association with myelomeningocele, without any neuromuscular repercussions, and the second case of a newborn at 10 days of age, presenting with a lumbosacral spina bifida and a uterine prolapse. They benefited from conservative medical treatment characterised by manual reduction of the prolapse in both cases with a favourable evolution. In the case of spina bifida, a cure of myelomeningocele was performed surgically with simple postoperative course.

关键词： Spina Bifida Genital Prolapse Neonate Complications CHUD/BA

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Malignant Transformation of Cerebellar Pleomorphic Xanthoastrocytoma: A Case Report

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World Journal of Neuroscience 2017年第4期7卷 376-382页

作者： Oumar Coulibaly Mahamadou Dama Oumar Diallo quenum kouassi jean marie maurin kisito Li Gu Boubacar Sogoba Moussa Denou Sieleche Auxence Christ Youssouf Sogoba Mamadou Salia Diarra Alpha Singuépiré Drissa Kanikomo Hopital du Mali Bamako Mali Unité de Neurochirurgie Centre Hospitalier Départemental et Universitaire de Parakou Parakou Benin The First Affiliated Hospital of Medical School of Zhejiang University Zhejiang China Hopital Gabriel Touré Bamako Mali Hopital Mère-Enfant “Le Luxembourg” Bamako Mali

Pleomorphic xanthoastrocytoma (PXA) generally occurs in children and young adults and is classified as a low-grade astrocytic tumor with a potential favorable prognosis. But these data must be interpreted with much caution, because of some rapid progression or malignant transformation during the postoperative follow-up. We report herein a rare case of a cerebellar PXA manifested as a benign lesion at first time in a 39 year-old woman, but with malignant transformation two years later. In this paper, we discuss the clinical signs, radiological findings and the therapeutic data on the subject according to literature review.

关键词： Pleomorphic Xanthoastrocytoma Cerebellar Malignant

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Management and Outcome of Acute Subdural Hematoma in Gabriel TouréHospital

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Open Journal of Emergency Medicine 2022年第1期10卷 48-53页

作者： Youssouf Sogoba Drissa Kanikomo quenum kouassi jean marie kisito Moussa Diallo Bakary Dembélé Boubacar Sogoba Djènè Kourouma Izoudine Blaise Koumaré Seybou Hassane Diallo Hamidou Almeimoune Moustapha Mangané Thierno Madane Diop Oumar Coulibaly Mamadou Salia Diarra Mahamadou Dama Oumar Diallo Youssoufa Maiga Djibo Mahamane Diango Department of Neurosurgery Gabriel Touré Teaching Hospital Bamako Mali Neurosurgeon University of Parakou Parakou Benin Department of Neurology Gabriel Touré Teaching Hospital Bamako Mali Department of Emergency Care Gabriel Touré Teaching Hospital Bamako Mali Department of Neurosurgery H&#244 pital du Mali Bamako Mali Department of Neurosurgery H&#244 pital Luxambourg Bamako Mali

Background: Traumatic Brain Injury (TBI) is a major health problem worldwide. It is the main cause of trauma mortality. Acute subdural hematoma (ASDH) has a reputation for being the most serious of all posttraumatic head injuries. Its frequency is estimated to be 1% to 5% of all head injuries and 22% of severe head injuries. The aim of this study was to assess the epidemiological, clinical and prognosis aspects of ASDH in our department. Material and Methods: This prospective study, from January to December 2019, included 57 patients admitted to the Gabriel Touré Teaching Hospital for ASDH. Patients underwent detailed clinical and radiological evaluation and ASDH was diagnosed by non-contrast computed tomography (CT) scan. Functional outcome was evaluated 6 months after injury by Glasgow Outcome Scale. Results: During the study period, 662 patients were admitted for TBI including 57 (8.61%) cases of ASDH. The mean age was 34 years with extremes of 2 and 77 years. There was a male predominance with 52 (91.2%). The main cause of trauma was motor vehicle accidents in 38 (66.6%) patients. According to the Glasgow coma scale (GCS), 33 (57.9%) patients were classified mild (Table 2). The thickness of the hematoma was more than 1 cm in 13 (22.8%) patients and less than 1 cm in 44 (77%) patients. Surgical treatment was performed in 13 (22.8%) patients. The outcome was favorable in 30 (52.6%) patients and the mortality rate was 33.3%. Conclusion: ASDH remains a difficult challenge because of the high mortality. The mortality rate remains high particularly in patient with poor GCS score at admission.

关键词： Acute Subdural Hematoma Traumatic Brain Injury Outcome

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