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Epidemiological and Diagnostic Features of Non-Traumatic Gonalgia in Adults in Bouake (Ivory Coast): About 140 Patients

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Open Journal of Rheumatology and Autoimmune Diseases 2023年第4期13卷 78-87页

作者： kouakou ehaulier soh christian louis Sougué Charles Yao Konan Joe Clauvis Traore Aissata Koffi Joseph Kan Enock Goua Jean Jacques Same Bebey Francine Goupille Phillipe Daboiko Jean Claude Felix Rheumatology Department University Hospital Center Bouaké Bouaké C&#244te d’Ivoire Internal Medicine Department University Hospital Center Sour&#244 Sanou Bobo Dioulasso Burkina Faso Rheumatology Department Laquintinie Hospital Douala Cameroon Rheumatology Department University Hospital Center Tours France

Background: Non traumatic gonalgia is the second most common reason for rheumatology consultations and accounted for 15.6% of rheumatological disorders in Abidjan. Objective: The aim of this work was to study the epidemiological and diagnostic features of non-traumatic gonalgia (NTG) in a black adult population from sub-Saharan Africa. Patients and Methods: This was a five-year retrospective descriptive study (January 2014 to December 2018) of black sub-Saharan African adult patients with non traumatic gonalgia seen in the rheumatology department of the Bouake University Hospital in Côte d’Ivoire. Results: Of 2198 patients seen for rheumatological conditions, 140 had non traumatic gonalgia (6.4%). The mean age of patients was 56.13 ± 13.3 years (extremes 20 and 87 years), and the sex ratio was 0.43 (42 men and 98 women). Gonalgia without swelling was observed in 33.6% of cases. Symptoms were predominantly progressive (97.1%), chronic (82.1%) and bilateral (50%). The causes of TNM were gonarthrosis (85%), septic arthritis (7.1%), reactive arthritis (2.9%), gout (2.9%), rheumatoid arthritis (1.4%) and chondrocalcinosis (0.7%). Gonarthrosis (119/140) was bilateral in 65 patients, bi- or tri-compartmental in 83, radiographic stage (Kellgren and Lawrence) III in 80 and IV in 15. A germ was isolated in two cases of septic arthritis (methicillin-sensitive Staphylococcus aureus and Streptococcus pneumoniae). Conclusion: GNT is common in rheumatology practice in Bouake, and mainly affects women in their fifties. It is most often a chronic bilateral gonalgia, with gonarthrosis as the main etiology.

关键词： Non-Traumatic Gonalgia Gonarthrosis Bouake

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Clinical Profile of Juvenile Idiopathic Arthritis (JIA) in a Semi-Rural Ivorian Environment

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Open Journal of Pediatrics 2024年第6期14卷 1050-1057页

作者： Aissata Doucoure Traore Joe-Clovis Yao Kan Enock Joseph Koffi Jean-Jacque Goua ehaulier soh christian louis kouakou Felix Jean-Claude Daboiko Rheumatology Department Bouake Hospital and University Centre Bouake Ivory Coast

Objectives: To describe the clinical profile of juvenile idiopathic arthritis (JIA) in a semi-rural Ivorian setting: the rheumatology department of the Bouaké University Hospital (CHU.B). Patients and methods: This was a descriptive cross-sectional study from January 2018 to December 2023 in the rheumatology department of the CHU.B. The study focused on the epidemiological, diagnostic and therapeutic data of children followed for JIA on the basis of the classification criteria of the International League of Associations for Rheumatology (ILAR). Excel 2019 software was used to analyse the data. Results: Over a 6-year period, JIA represented 0.29% (11/3780) of all rheumatological conditions and 1.40% (11/782) of childhood rheumatic diseases. The mean age of the children at diagnosis was 13.09 ± 3.01 years, and the mean age at onset of the disease was 8.54 years. There were 6 girls and 5 boys. Joint involvement was the main reason for consultation and hospitalisation, accounting for 81.81% (9) of cases. There was a family history in 3 children (27.3%). The clinical forms were as follows: systemic 27.27% (3), oligoarticular 27.27% (3), polyarticular with rheumatoid factor negative 27.27% (3), polyarticular with rheumatoid factor positive 9.09 (1), arthritis with enthesitis 9.09 (1). JIA was discovered at steinbrocker functional stages II and III. Treatment included NSAIDs 72.72% (8), corticosteroid therapy combined with methotrexate and hydroxychloroquine 54.54% (6) and rehabilitation 63.63% (7). Conclusion: JIA is a little-known disease in the semi-rural environment of Côte d’Ivoire. It is characterised by a long delay in diagnosis in relation to poverty and the lack of recourse to alternative medicine in our populations;hence, it is important to raise awareness of the condition among the population and practitioners. Multidisciplinary intervention would improve the diagnosis and management of children with JIA.

关键词： JIA Profile Semi-Rural Environment Côte d’Ivoire

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Multilevel Cervicothoracic and Lumbar Pott’s Disease: About Three New and Unusual Cases in the Rheumatology Department of the Teaching Hospital of Cocody in Abidjan (Côte d’Ivoire)

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Open Journal of Rheumatology and Autoimmune Diseases 2015年第2期5卷 23-27页

作者： Mohamed Diomandé ehaulier soh christian louis kouakou Tamo Estelle Mégné Mariam Gbané-Koné Abidou Kawele Coulibaly Edmond Eti Marcel N’zué kouakou Department of Rheumatology of University Hospital Center of Cocody Abidjan C&#244te d’Ivoire Department of Rheumatology of University Hospital Center of Bouaké Bouaké C&#244te d’Ivoire

Pott’s disease usually affects two contiguous vertebrae or two spinal levels. The involvement of the three cervicothoracic and lumbar levels is rarely described. Only three cases have been described in the literature to our knowledge. The authors report three new cases of tuberculous spondylodiscitis of cervicothoracic and lumbar site. Our three cases were characterized by symptoms similar to the other topographical forms of Pott’s disease. A predisposing factor is often identified like the infection with human immunodeficiency virus. The definitive diagnosis was made in two cases by identifying acid and alcohol-fast bacilli for one case and by histology for the other case. For the third case, there was a diagnostic presumption reinforced by the satisfactory outcome on tuberculosis chemotherapy for a period of 12 months. The multilevel nature of diseases does not influence the effectiveness of treatment of this form of spinal tuberculosis.

关键词： Pott’s Disease Spondylodiscitis Bone and Joint Tuberculosis Abidjan

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Systemic Form of Juvenile Idiopathic Arthritis: Epidemiological, Clinical, Paraclinical and Therapeutic Aspects of 13 Cases in Abidjan

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Open Journal of Rheumatology and Autoimmune Diseases 2017年第2期7卷 103-110页

作者： Mohamed Diomandé Abidou Kawélé Coulibaly Astrid Nawé Ngandeu Cyprien kouakou ehaulier soh christian louis kouakou Kouassi Jean Mermoz Djaha Mariam Gbané-Koné Baly Ouattara Edmond Eti Jean Claude Daboiko Marcel N’zué kouakou Department of Rheumatology University Hospital Center of Cocody Abidjan C&#244te d’Ivoire Department of Pediatrics University Hospital Center of Cocody Abidjan C&#244te d’Ivoire Department of Rheumatology University Hospital Center of Bouaké Bouaké C&#244te d’Ivoire

Objective: To describe the epidemiological, clinical, paraclinical and therapeutic aspects of systemic juvenile idiopathic arthritis observed in Abidjan. Materials and Method: This retrospective and descriptive study covered 13 children suffering from systemic juvenile idiopathic arthritis selected in the Rheumatology Department of University Hospital Center of Cocody in Abidjan (Cote d’Ivoire) from January 2005 to December 2015. We were interested to the sociodemographical, clinical, paraclinical and therapeutic aspects. Results: The systemic form of the juvenile idiopathic arthritis represented 0.2% of the 4608 rheumatologic diseases and 70.58% of the JIA. We selected 6 boys and 7 girls, with an average age of 10.8 years and mostly going to school (84.61%). The diagnostic delay was 18 months. The main clinical signs were fever and joint damage observed each in 100% of cases, impaired general condition (92.30%) and tumor syndrome (83.33%). Biological signs were characterized by hyperleukocytosis (69.20%) and the presence of a biologic inflammatory syndrome (on average, erythrocyte sedimentation rate 59.6 mm and C Reactive Protein 56.4 mg/l). The cervical damage was the essential functional complication (38.46%). The major treatment has been a therapeutic combination based on corticotherapy and methotrexate (100%) with 1 death case by macrophage activation syndrome. Conclusion: Systemic juvenile idiopathic arthritis is rarely diagnosed in the rheumatologic practice in Abidjan. It concerns children relatively big, and is characterized by a febrile polyarthritis with impaired general condition and tumor syndrome. This systemic form is treated by corticotherapy and methotrexate.

关键词： Systemic Idiopathic Juvenile Arthritis Juvenile Idiopathic Arthritis Profile Children Abidjan

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Paraclinical, Therapeutic and Evolutionary Profile of Osteoarticular Tuberculosis: A Report about 550 Cases in Abidjan

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Open Journal of Rheumatology and Autoimmune Diseases 2015年第4期5卷 131-136页

作者： Mohamed Diomandé Fulgence Kaboré ehaulier soh christian louis kouakou Mariam Gbané-Koné Abidou Kawélé Coulibaly Kouassi Jean Mermoz Djaha Baly Ouattara Edmond Eti Jean Claude Daboiko Marcel N’zué kouakou Department of Rheumatology University Hospital Center of Cocody Abidjan C&ocircte d’Ivoire Department of Rheumatology University Hospital Center of Bouaké Bouaké C&ocircte d’Ivoire

Objective: To describe paraclinical, therapeutic and evolutionary aspects of osteoarticular tuberculosis in Abidjan. Materials and Method: We realized a descriptive retrospective study carried out in the Rheumatology Department of the University Hospital Center of Cocody in Abidjan about 550 patients over a period of 10 years from January 2004 to December 2013. The paraclinical, therapeutic and evolutionary data had interested us. Results: Osteoarticular tuberculosis represented 12.13% of 4531 rheumatic diseases identified during the study period. The tuberculin skin test was positive in 78.49% of cases. An inflammatory syndrome was present with erythrocyte sedimentation rate and C-reactive protein respectively into 69.45% and 76.54% of cases. The research of Mycobacterium tuberculosis was realized into 176 of cases which 50% was positive. Polymerase chain reaction and biopsy of tissue were performed respectively in 8 and 6 cases. Plain radiography (89.82%) and computed tomography (83.63%) were the most realized imaging. Computed tomography has contributed for the diagnostic in 99.78% of cases. The majority of our patients (82.91%) received anti-tuberculous treatment which consisted of two months of combination of rifampicin (R), isoniazid (H), pyrazinamide (Z) and Ethambutol (E) (2RHZE), followed by 10 months of rifampicin (R) and isoniazid (H) (10 RH). The outcome in patients on this treatment was favorable in 528 cases (96%). Conclusion: This study revealed that the research of Mycobacterium tuberculosis was often realized and positive. On the contrary, polymerase chain reaction and biopsy of tissue were rarely performed. The main imaging is computed tomography. Our protocol of treatment is effective.

关键词： Osteoarticular Tuberculosis Biology Imaging Abidjan

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Epidemiological and Clinical Aspects of Hospitalized Patients with Chronic Rheumatic Disease at Cocody University Hospital in Abidjan

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Open Journal of Rheumatology and Autoimmune Diseases 2023年第3期13卷 65-70页

作者： ehaulier soh christian louis kouakou Charles Sougué Konan Joe Clauvis Yao Aissata Traore Joseph Kan Enock Koffi Jean Jacques Goua Francine Same Bebey Phillipe Goupille Jean Claude Felix Daboiko Rheumatology Department Bouake University Hospital Bouake C&#244te d’Ivoire Rheumatology Department Cocody University Hospital Abidjan C&#244te d’Ivoire Department of Internal Medicine Sour&#244 Sanou University Hospital Bobo Dioulasso Burkina Faso Rheumatology Department Laquintinie Hospital Douala Cameroon Rheumatology Department Tours University Hospital Tours France

Objective: To study the epidemiological and diagnostic features of chronic rheumatic disease (CRD) in a black population in sub-Saharan Africa. Patients and Methods: Retrospective descriptive study over eight years (January 2005 to December 2012) of patients seen for CRD in rheumatology hospitalization at the CHU de Cocody in Abidjan, Côte d’Ivoire. Results: Of 3147 hospitalized patients, 92 had CRD, a frequency of 2.9%. The mean age of patients was 43.50 ± 15.6 years (extremes: 10 to 79 years). The sex ratio was 0.08 (7 men and 85 women). The socio-economic level was low in 44 patients (47.8%), medium in 44 patients (47.8%), and high in 4 patients (4.4%). The reasons for consultation were polyarthritis (64.1%), polyarthralgia (30.4%), and oligoarthritis (5.4%). The mean duration of symptomatology was 19 months (range: 3 to 20 years). The mean length of hospital stay was 14.2 ± 7.7 days (range: 2 to 36 days). The CRD observed were: rheumatoid arthritis (59.8%), systemic lupus erythematosus (23.9%), mixed connective tissue disease (6.5%), undifferentiated connective tissue disease (3.3%), polymyositis (3.3%), systemic scleroderma (2.2%), and systemic vasculitis (1%). Conclusion: CRD is not uncommon in rheumatology hospitals in Abidjan. Diagnostic delays are long, and rheumatoid arthritis and systemic lupus erythematosus are the most frequently encountered conditions.

关键词： Chronic Rheumatic Disease Rheumatoid Arthritis Lupus Abidjan

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Epidemiological, Clinical and Paraclinical Profile of Osteoarthritis of the Lower Limbs in Obese Patients at the Cocody University Teaching Hospital

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Open Journal of Rheumatology and Autoimmune Diseases 2024年第2期14卷 69-76页

作者： Nzima Brice Kollo Aboubakar Bamba¹ Aboubacar Sidiki Condé Nzima Hilary Ngon Kanbaye Medom Ada Nina Kpami Yaya Coulibaly Kan Joseph Enoch Koffi ehaulier soh christian louis kouakou Mohamed Diomandé¹ Edmond Eti Rheumatology Department Cocody University Hospital Abidjan C&#244te d&#8217Ivoire Internal Medicine Department Yaounde University Hospital Yaounde Cameroon Rheumatology Department Bouake University Hospital Bouake C&#244te d&#8217Ivoire

Objective: To describe the epidemiological, clinical and paraclinical characteristics of osteoarthritis of the lower limbs in obese patients at the Cocody University Teaching Hospital. Methodology: This was an analytical cross-sectional study carried out in the rheumatology department of the Cocody UTH in Abidjan (Ivory Coast) from March 1 to April 30 2023. Patients who came for rheumatology consultation presenting with mechanical arthralgia of the lower limbs, who were obese, had radiographic images were included. All patients without radiographic images were excluded. Obesity was defined as a body mass index (BMI) greater than or equal to 30 kg/m. The Chi2 test was used to compare proportions and determine the existence of associations between osteoarthristis and obesity, obesity severity and radiographic stage of osteoarthritis as well as the functional impact. A p-value below a predefined threshold (p = 0,05) indicates a significant relationship between the variables. Result: Out of 185 patients received for osteoarthritis of the lower limbs during the study period, 136 were obese (74%). There were 115 women (84.6%) with an average age of 56.03 with a standard deviation of 12.72 years (extremes: 22 and 84 years). The main socio-professional category was the informal sector (30%). The majority of patients had a low socio-economic level (80.2%) and lived in urban areas (92.6%). The most common past medical history was hypertension (33.08%) followed by peptic ulcer disease (16.91%). Patients had a body mass index class 1 (81.6%), class 2 (15.40%) and class 3 (2.90%). The average duration of symptom progression until diagnosis was 11 months. Genu varum was the main static disorder (56.10%) and the knee joint was the dominant topography (90.4%) with a bilateral localization (80%). The average Lequesne index was greater than 8 (59.5%). The Kellgren and Lawrence radiographic stages were stage 1 (9.20%), stage 2 (46.90%), stage 3 (29.20%) and stage 4 (6.90%).

关键词： Osteoarthritis Lower Limbs Obesity Abidjan

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