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Benign esophageal stricture after thermal injury treated with esophagectomy and ileocolon interposition

World Journal of Gastroenterology 2014年第27期20卷 9205-9209页

作者： Toshihiro Kitajima kota momose Seigi Lee Shusuke Haruta Hisashi Shinohara Masaki Ueno Takeshi Fujii Harushi Udagawa Department of Digestive Surgery Toranomon Hospital 2-2-2 Toranomon Minato-ku Tokyo 105-8470 Japan Department of Pathology Toranomon Hospital 2-2-2 Toranomon Minato-ku Tokyo 105-8470 Japan

Thermal injuries of the esophagus are rare causes of benign esophageal stricture, and all published cases were successfully treated with conservative management. A 28-year-old Japanese man with a thermal esophageal injury caused by drinking a cup of hot coffee six months earlier was referred to our hospital. The hot coffee was consumed in a single gulp at a party. Although the patient had been treated conservatively at another hospital, his symptoms of dysphagia gradually worsened after discharge. An upper gastrointestinal endoscopy and computed tomography revealed a pinhole like area of stricture located 19 cm distally from the incisors to the esophagogastric junction, as well as circumferential stenosis with notable wall thickness at the same site. The patient underwent a thoracoscopic esophageal resection with reconstruction using ileocolon interposition. The pathological findings revealed wall thickening along the entire length of the esophagus, with massive fibrosis extending to the muscularis propria and adventitia at almost all levels. Treatment with balloon dilation for long areas of stricture is generally difficult, and stent placement in patients with benign esophageal stricture, particularly young patients, is not yet widely accepted due to the incidence of late adverse events. Considering the curability and qualityof-life associated with a long expected prognosis, we determined that surgery was the best treatment option for this young patient. In this case, we decided to perform an esophagectomy and reconstruction with ileocolon interposition in order to preserve the reservoir function of the stomach and to avoid any problems related to the reflux of gastric contents. In conclusion, resection of the esophagus is a treatment option in patients with benign esophageal injury, especially in cases involving young patients with refractory esophageal stricture. In addition, ileocolon interposition may help to improve the quality-of-life of patients.

关键词： Thermal injury Benign esophageal stricture Esophageal resection Ileocolon interposition Video-assisted thoracic surgery

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Bronchial bleeding caused by recurrent pneumonia after radical esophagectomy for esophageal cancer

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World Journal of Gastroenterology 2015年第11期21卷 3394-3401页

作者： Toshihiro Kitajima kota momose Seigi Lee Shusuke Haruta Masaki Ueno Hisashi Shinohara Sakashi Fujimori Takeshi Fujii Ryoji Takei Tadasu Kohno Harushi Udagawa Department of Gastroenterological Surgery Toranomon Hospital Department of Thoracic Surgery Toranomon Hospital Department of Pathology Toranomon Hospital Department of Radiology Toranomon Hospital

We herein report a case of bronchial bleeding afterradical esophagectomy that was treated with lobectomy.A 65-year-old male who underwent subtotal esophagectomy with three-field lymph node dissection for esophageal carcinoma was referred to our hospital because of sudden *** the esophagectomy,bilateral vocal cord paralysis was observed,and the patient suffered from repeated episodes of aspiration *** revealed hemosputum in the right middle lobe bronchus,and contrast-enhanced computed tomography showed tortuous arteries arising from the right inferior phrenic artery and left subclavian artery toward the right middle lobe *** bronchial arterial embolization was performed twice to control the recurrent hemoptysis,the procedures were *** middle lobectomy was therefore performed via video-assisted thoracic *** bronchial arterys with medial hypertrophy and overgrowth of the small branches were noted near the bronchus in the resected *** patient recovered uneventfully and was discharged on postoperative day 14.

关键词： Hemoptysis Esophagectomy Recurrent laryngeal nerve

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Japanese Sign Language Recognition by Combining Joint Skeleton-Based Handcrafted and Pixel-Based Deep Learning Features with Machine Learning Classification

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Computer Modeling in Engineering & Sciences 2024年第6期139卷 2605-2625页

作者： Jungpil Shin Md.Al Mehedi Hasan Abu Saleh Musa Miah kota Suzuki Koki Hirooka School of Computer Science and Engineering The University of AizuAizuwakamatsu965-8580Japan Department of Computer Science&Engineering Rajshahi University of Engineering&TechnologyRajshahi6204Bangladesh

Sign language recognition is vital for enhancing communication accessibility among the Deaf and hard-of-hearing *** Japan,approximately 360,000 individualswith hearing and speech disabilities rely on Japanese Sign Language(JSL)for ***,existing JSL recognition systems have faced significant performance limitations due to inherent *** response to these challenges,we present a novel JSL recognition system that employs a strategic fusion approach,combining joint skeleton-based handcrafted features and pixel-based deep learning *** system incorporates two distinct streams:the first stream extracts crucial handcrafted features,emphasizing the capture of hand and body movements within JSL ***,a deep learning-based transfer learning stream captures hierarchical representations of JSL gestures in the second ***,we concatenated the critical information of the first stream and the hierarchy of the second stream features to produce the multiple levels of the fusion features,aiming to create a comprehensive representation of the JSL *** reducing the dimensionality of the feature,a feature selection approach and a kernel-based support vector machine(SVM)were used for the *** assess the effectiveness of our approach,we conducted extensive experiments on our Lab JSL dataset and a publicly available Arabic sign language(ArSL)*** results unequivocally demonstrate that our fusion approach significantly enhances JSL recognition accuracy and robustness compared to individual feature sets or traditional recognition methods.

关键词： Japanese Sign Language(JSL) hand gesture recognition geometric feature distance feature angle feature GoogleNet

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Recent advancements in the diagnosis and treatment of acral melanoma

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第2期25卷 106-122页

作者： Ahmad ALHASKAWI Sohaib Hasan Abdullah EZZI Yanzhao DONG Haiying ZHOU Zewei WANG Jingtian LAI Chengjun YAO Vishnu Goutham kota Mohamed Hasan Abdulla Hasan ABDULLA Hui LU Department of Orthopedics the First Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou310003China Department of Orthopaedics Third Xiangya HospitalCentral South UniversityChangsha410013China Zhejiang University School of Medicine Hangzhou310058China Alibaba-Zhejiang University Joint Research Center of Future Digital Healthcare Zhejiang UniversityHangzhou310058China

Acral melanoma(AM)is the most common histologic subtype of melanoma in dark-skinned patients and is associated with a worse prognosis and a high mortality rate,largely due to the inconspicuous nature of early-stage lesions,which can lead to late *** of the overlapping clinical and histopathological features of AM with other forms of cutaneous melanomas,early detection of AM requires a multidisciplinary approach that integrates various diagnostic modalities,including clinical examination,dermoscopy,histopathology,molecular testing,radiological imaging,and blood *** surgery is the preferred method of treatment for AM,other therapeutic options may be employed based on the stage and underlying etiology of the *** checkpoint inhibitors,molecular targeted therapy,radiotherapy,chemotherapy,and oncolytic virotherapy represent promising advanced treatment options for *** this review,we provide an overview of the latest advancements in diagnostic and therapeutic methods for AM,highlighting the importance of early detection and the prompt,individualized management of this challenging disease.

关键词： Acral melanoma Acral lentiginous melanoma Acral nevus Cutaneous malignant melanoma Dermoscopy Oncolytic virotherapy

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Fine 3D control of THz emission in air with dual femtosecond laser pre-pulses at tunnelling ionisation regime

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Light(Advanced Manufacturing) 2024年第3期5卷 62-74页

作者： Hsin-Hui Huang Takeshi Nagashima kota Kumagai Yoshio Hayasaki Saulius Juodkazis Vladimir T.Tikhonchuk Koji Hatanaka Optical Sciences Centre ARC Training Centre in Surface Engineering for Advanced Materials(SEAM)School of ScienceSwinburne University of TechnologyHawthornVictoria 3122Australia Faculty of Science and Engineering Setsunan University17-8 Ikeda-NakamachiNeyagawaOsaka572-8508Japan Center for Optical Research and Education(CORE) Utsunomiya University7-1-2 YotoUtsunomiya 321-8585Japan WRH Program International Research Frontiers Initiative(IRFI)Tokyo Institute of Technology Nagatsuta-choMidori-kuYokohamaKanagawa 226-8503 Japan Laser Research Center Physics FacultyVilnius UniversitySauletekio Ave.1010223 VilniusLithuania Centre Lasers Intenses et Applications Universite de Bordeaux351Cours de la Liberation33405 Talence cedexFrance Extreme Light Infrastructure ERIC ELI Beamlines FacilityZa Radnicic 83525241 Dolni BřežanyCzech Republic Organization for Research Strategy and Development Okayama Univ.1-1-1 Tsushima-nakaKita-kuOkayama 700-8530Japan

Emission of THz radiation from air breakdown at focused ultra-short fs-laser pulses(800 nm/35 fs)was investigated for the 3D spatio-temporal control where two pre-pulses are used before the *** laser pulse induced air breakdown forms a~120μm-long focal volume generate shockwaves which deliver a denser air into the focal region of the main pulse for enhanced generation of THz radiation at 0.1-2.5 THz spectral *** intensity of 162 pre-and main-pulses was at the tunnelling ionisation intensities(1-3)×10 W/cm and corresponded to sub-critical(transparent)plasma formation in *** analysis of THz radiation revealed that orientation of the air density gradients generated by pre-pulses and their time-position locations defined the ellipticity of the generated THz electrical *** rotational component of electric current is the origin of THz radiation.

关键词： THz radiation Femtosecond laser induced breakdown Air breakdown spatio-temporal control

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Prediction of wall deposition behaviour in a pilot-scale spray dryer using deposition correlations for pipe flows

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第2期8卷 301-312页

作者： kota K. LANGRISH T.A.G. School of Chemical and Biomolecular Engineering University of Sydney Sydney Australia

The particle deposition behaviour of skim milk, water and maltodextrin in the conical section of a pilot-scale spray dryer was predicted using simple correlations for particle depositions in pipes. The predicted particle deposition fluxes of these materials were then compared with the measured deposition fluxes. The predicted particle deposition regimes of the spray dryer were expected to be in the diffusional and mixed (diffusional and inertial) regimes, but the experimental results suggested that the particle deposition was mainly in the inertial regime. Therefore, using the pipe correlations for predicting deposition in a pilot-scale spray dryer suggests that they do not sufficiently represent the actual deposition behaviour. This outcome indicates that a further study of particle flow patterns needs to be carried out using numerical simulations (computational fluid dynamics, CFD) in view of the additional geometrical complexity of the spray dryer.

关键词： Spray dryer Pipe correlations Particle deposition

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肢端黑色素瘤的诊断和治疗进展（英文）

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第2期 106-123页

作者： Ahmad ALHASKAWI Sohaib Hasan Abdullah EZZI 董延钊周海英王泽伟来经天姚成俊 Vishnu Goutham kota Mohamed Hasan Abdulla Hasan ABDULLA 卢荟浙江大学医学院附属第一医院骨科中南大学湘雅三医院骨科浙江大学医学院阿里巴巴-浙江大学未来数字医疗联合研究中心

肢端黑色素瘤（AM）是深色皮肤患者中最常见的黑色素瘤组织学亚型，常伴有更差的预后和高死亡率，主要原因为早期病变的不典型特征导致诊断延误。由于AM的临床和组织病理学特征与其他形式的皮肤黑色素瘤相近，其早期检测需要综合各种诊... 详细信息

肢端黑色素瘤（AM）是深色皮肤患者中最常见的黑色素瘤组织学亚型，常伴有更差的预后和高死亡率，主要原因为早期病变的不典型特征导致诊断延误。由于AM的临床和组织病理学特征与其他形式的皮肤黑色素瘤相近，其早期检测需要综合各种诊断模式的多学科方法，包括临床检查、皮肤镜检查、组织病理学检查、分子检测、放射学成像和血液检测。虽然手术是AM的首选治疗方法，但是根据疾病的分期和潜在病因，也可以采用其他治疗方案。免疫检查点抑制剂、分子靶向治疗、放疗、化疗和溶瘤病毒治疗在AM治疗上具有应用前景。在本文中，我们概述了AM诊断和治疗方法的最新进展，强调了早期发现和及时、个性化管理在这一具有挑战性疾病诊疗上的重要性。

关键词：肢端黑色素瘤肢端雀斑样黑色素瘤肢端痣皮肤恶性黑色素瘤皮肤镜检查溶瘤病毒治疗

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Influence of Diffuser on Aerodynamic Noise of a Forward Curved Fan

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Journal of Thermal Science 2013年第5期22卷 433-438页

作者： Soichi SASAKI kota SUZUKI Yuta Onomichi Hidechito Hayashi Division of System Science Graduate School of Engineering Nagasaki University1-14 Bunkyo-machi Nagasaki 852-8521 Japan Department of Advanced Engineering Graduate School of Engineering Nagasaki University1-14 Bunkyo-machi Nagasaki 852-8521 Japan

In order to clarify the influence of a diffuser on the charactersfics of a forward curved fan, the influence of the bare ratio and the outlet angle on the characteristics of the fan were measured through an experiment performed with an actual fan as well as through a numerical simulation, respectively. The mechanism of the discrete fre- quency noise generated by the separated flow of the diffuser was analyzed. The optimized bare ratio was ap- proximately 17%. The flow separated inside of the diffuser generated discrete frequency noise owing to the inter- action between the reversed flow from the diffuser and the impeller rotating at the blade passing frequency. The diffuser outlet angle influenced the pressure ratio more than that by the bare ratio. Furthermore, it was confirmed that restraining the separation in the diffuser effectively decreases the fan noise.

关键词： Pressure Drop Fan Aerodynamic Noise Internal Flow Separation

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Prediction of return of spontaneous circulation in outof-hospital cardiac arrest with non-shockable initial rhythm using point-of-care testing: a retrospective observational study

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World Journal of Emergency Medicine 2023年第2期14卷 89-95页

作者： kota Shinada Hiroyuki Koami Ayaka Matsuoka Yuichiro Sakamoto Department of Emergency and Critical Care Medicine Faculty of MedicineSaga UniversitySaga CitySaga Prefecture 849-8501Japan Division of Translational Research in Intensive Care Medicine Faculty of MedicineSaga UniversitySaga CitySaga Prefecture 849-8501Japan

BACKGROUND:Out-of-hospital cardiac arrest(OHCA) is a public health concern, and many studies have been conducted on return of spontaneous circulation(ROSC) and its prognostic *** thromboelastometry(ROTEM?), a point-of-care testing(POCT) method, has been useful for predicting ROSC in patients with OHCA, but very few studies have focused on patients with non-shockable rhythm. We examined whether the parameters of POCT could predict ROSC in patients with OHCA and accompanying non-shockable ***:This is a single-center, retrospective observational study. Complete blood count,blood gas, and ROTEM POCT measurements were used. This study included patients with nontraumatic OHCA aged 18 years or older who were transported to the emergency department and evaluated using POCT between January 2013 and December 2021. The patients were divided into the ROSC and non-ROSC groups. Prehospital information and POCT parameters were compared using receiver operating characteristic(ROC) curve analysis, and further logistic regression analysis was ***:Sixty-seven and 135 patients were in the ROSC and non-ROSC groups,respectively. The ROC curves showed a high area under the curve(AUC) for K^(+) of 0.77(95%confidence interval [CI]:0.71–0.83) and EXTEM amplitude 5 min after clotting time(A5) of 0.70(95%CI:0.62–0.77). The odds ratios for ROSC were as follows:female sex 3.67(95%CI:1.67–8.04);K^(+)0.64(95%CI:0.48–0.84);and EXTEM A5 1.03(95%CI:1.01–1.06).CONCLUSION:In OHCA patients with non-shockable rhythm, K^(+) level and the ROTEM parameter EXTEM A5 may be useful in predicting ROSC.

关键词： Rotational thromboelastometry Blood coagulation disorders Extrinsic pathway Potassium

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High accuracy offering attention mechanisms based deep learning approach using CNN/bi-LSTM for sentiment analysis

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International Journal of Intelligent Computing and Cybernetics 2022年第1期15卷 61-74页

作者： Venkateswara Rao kota Shyamala Devi Munisamy CSE Vel Tech Rangarajan Dr Sagunthala R&D Institute of Science and TechnologyChennaiIndia CSE Andhra Loyola Institute of Engineering and TechnologyVijayawadaIndia

Purpose-Neural network(NN)-based deep learning(DL)approach is considered for sentiment analysis(SA)by incorporating convolutional neural network(CNN),bi-directional long short-term memory(Bi-LSTM)and attention *** the conventional supervised machine learning natural language processing algorithms,the authors have used unsupervised deep learning ***/methodology/approach-The method presented for sentiment analysis is designed using CNN,Bi-LSTM and the attention ***2vec word embedding is used for natural language processing(NLP).The discussed approach is designed for sentence-level SA which consists of one embedding layer,two convolutional layers with max-pooling,oneLSTMlayer and two fully connected(FC)*** the system training time is 30 ***-The method performance is analyzed using metrics like precision,recall,F1 score,and *** is helped to reduce the complexity and Bi-LSTM is helped to process the long sequence input ***/value-The attention mechanism is adopted to decide the significance of every hidden state and give a weighted sum of all the features fed as input.

关键词： Sentiment analysis NLP Neural networks Bi-LSTM Attention mechanism Word embedding Dropout Fully connected(FC)layer Performance metrics

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