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Dynamic Lower-Limb Alignment Focusing on Gait Stability

Open Journal of Therapy and Rehabilitation 2022年第4期10卷 179-188页

作者： Kan Imai Takeshi Onishi koshiro sawada Department of Orthopaedics Kyoto Prefectural Rehabilitation Hospital for Mentally and Physically Disabled Kyoto Japan Department of Orthopaedics Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan Department of Consultation and Assessment Section Kyoto Prefectural General Family Support Center Kyoto Japan Department of Rehabilitation Medicine Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan Department of Multidisciplinary Promote for Physical Activity University Hospital Kyoto Prefectural University of Medicine Kyoto Japan

Introduction: Prosthetic limbs must be developed with proper alignment to facilitate safe and efficient gait patterns. This study aimed to identify factors impacting clinically proper gait patterns by objectively evaluating them in persons with lower-limb amputations who use prosthetic limbs. Materials and Methods: This non-experimental descriptive study assessed 58 persons with amputation who used prosthetic limbs. The mechanical axis angle (MAA) of the lower limb during the heel contact, midstance, and toe-off phases and the angle between the tube and floor during the midstance phase were measured using coronal plane gait images. We also investigated whether the MAA and tube angle during the midstance phase have a multimodal distribution. In case of multimodal distributions, we tested for significant between-group differences in patient characteristics. Results: The MAA and tube angle in the coronal plane during the midstance phase had a bimodal distribution (mean 0°). There was a significant difference in the duration of prosthetic limb use between the MAA < 0° and ≥0° groups during the midstance phase. Deviations in the lower limb MAA between the heel contact and midstance phases were 3.3° ± 2.2° and 3.1° ± 2.3° for persons with lower limb amputations in the MAA Conclusions: In this study, prosthetic alignment during the midstance phase had a bimodal distribution. In both groups, deviations in the lower limb MAA were aligned to be approximately 3°.

关键词： Prosthetic Limbs Alignment Gait Below-the-Knee Amputation

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Risk and Protective Factors Associated with Depression and Anxiety among Pregnant Women during the COVID-19 Pandemic

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Health 2024年第1期16卷 37-51页

作者： Maiko Manaka Miyako Tsuda Moe Fujitani Ai sawada Nanae Akatsuka Ayako Sasaki Faculty of Nursing Osaka Medical and Pharmaceutical University Takatsuki Japan Osaka City Juso Hospital Osaka Japan Osaka City General Hospital Osaka Japan

Background: The coronavirus disease (COVID-19) pandemic has impacted perinatal women’s mental health. However, protective factors associated with depression among pregnant Japanese women during the pandemic have not been reported. Purpose: The present study investigated the risk and protective factors associated with depression and anxiety among pregnant women during the COVID-19 pandemic. Methods: An online questionnaire was administered to 157 pregnant women between October 2022 and May 2023 at two general hospitals in Japan. The Japanese versions of the Patient Health Questionnaire-9 (PHQ-9) and General Anxiety Disorder-7 (GAD-7) were used to assess symptoms of depression and anxiety. The χ2 test or Fisher’s exact test and multivariate logistic regression model were used to examine factors associated with depression and anxiety among pregnant women. Results: Overall, 47.1% and 35.7% of the pregnant women reported depressive and anxiety symptoms, respectively. A “history of mental illness” was a risk factor for depression and anxiety among pregnant women during the COVID-19 pandemic. Additionally, unmarried status was a risk factor for anxiety among pregnant women, whereas outdoor and indoor exercises were protective factors against depression and anxiety, respectively. Conclusions: Exercise may have protected pregnant women from depression and anxiety during the COVID-19 pandemic. Encouraging exercise may help maintain the mental health of pregnant women who do not have exercise restrictions.

关键词： Depression Anxiety Factors Pregnancy COVID-19 Pandemic

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日本百年石质文物保护:从技术演进到大遗址保护的全景探析

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华夏考古 2024年第3期 125-129页

作者： [日]泽田正昭雷欣怡(译) 日本奈良文化财研究所成都博物馆四川成都市610015

人类创造并传承至今的历史,启示着人类社会的理想状态和前进方向。此中,文化遗产更被誉为人类社会的指南针,是历史的重要物证。尤其近年来,政府极力主张它们应作为旅游资源被有效利用,许多地方率先加强行政效能到地方文化的振兴中,依托... 详细信息

人类创造并传承至今的历史,启示着人类社会的理想状态和前进方向。此中,文化遗产更被誉为人类社会的指南针,是历史的重要物证。尤其近年来,政府极力主张它们应作为旅游资源被有效利用,许多地方率先加强行政效能到地方文化的振兴中,依托当地历史文化,通过世界遗产名录活动的开展和文化遗产的认定,达到地方振兴的目的。像这样将文化遗产作为媒介,举办地域认同感的文化活动也成为近年的趋势。

关键词：世界遗产名录文化遗产石质文物保护日本百年大遗址保护技术演进重要物证指南针

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Phylogenetic placement and diet of homalopsid snake Miralia alternans (Ruess,1833)

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Zoological Research 2022年第5期43卷 734-737页

作者： Ibuki Fukuyama Tomonori Kodama koshiro Eto Masafumi Matsui Mohamad Yazid Hossman Kanto Nishikawa Graduate School of Human and Environmental Studies Kyoto UniversityYoshida-NihonmatsuSakyoKyoto 606-8501Japan Graduate School of Science Kyoto UniversityKitashirakawa-OiwakeSakyoKyoto 606-8502Japan Kitakyushu Museum of Natural History&Human History Higashida 2-4-1YahatahigashiKitakyushuFukuoka 805-0071Japan Research Developmentand Innovation DivisionForest Department SarawakKuchingSarawak 93250Malaysia Graduate School of Global Environmental Studies Kyoto UniversityYoshida-HonmachiSakyoKyoto 606-8501Japan

DEAR EDITOR,Miralia alternans(Ruess,1833)is distributed in Borneo,Sumatra,and Java in Southeast *** species is morphologically similar to Raclitia indica,a monotypic genus known from Peninsular ***,we collected a juvenile specimen of *** from Borneo,and report on its coloration in life and first prey item recovered from the *** also explored the phylogenetic position of the genus using molecular phylogenetic analysis of mitochondrial DNA(mtDNA)gene cytochrome b(cyt b)and nuclear gene prolactin receptor(PRLR),confirming *** as sister to ***,with the two genera exhibiting relatively high genetic divergence in cyt b(13.0%-13.1%).

关键词： EDIT fir Java

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Bayesian optimization with experimental failure for high-throughput materials growth

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npj Computational Materials 2022年第1期8卷 1746-1754页

作者： Yuki K.Wakabayashi Takuma Otsuka Yoshiharu Krockenberger Hiroshi sawada Yoshitaka Taniyasu Hideki Yamamoto NTT Basic Research Laboratories NTT CorporationAtsugiKanagawa243-0198Japan NTT Communication Science Laboratories NTT CorporationSoraku-gunKyoto619-0237Japan

A crucial problem in achieving innovative high-throughput materials growth with machine learning,such as Bayesian optimization(BO),and automation techniques has been a lack of an appropriate way to handle missing data due to experimental ***,we propose a BO algorithm that complements the missing data in optimizing materials growth *** proposed method provides a flexible optimization algorithm that searches a wide multi-dimensional parameter *** demonstrate the effectiveness of the method with simulated data as well as in its implementation for actual materials growth,namely machine-learning-assisted molecular beam epitaxy(ML-MBE)of SrRuO_(3),which is widely used as a metallic electrode in oxide *** the exploitation and exploration in a wide three-dimensional parameter space,while complementing the missing data,we attained tensile-strained SrRuO3 film with a high residual resistivity ratio of 80.1,the highest among tensile-strained SrRuO3 films ever reported,in only 35 MBE growth runs.

关键词： optimization strained resistivity

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Ultrasound-guided rectus sheath block for anterior cutaneous nerve entrapment syndrome after laparoscopic surgery:A case report

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World Journal of Clinical Cases 2022年第7期10卷 2357-2362页

作者： Ryuji sawada Kunitaro Watanabe Joho Tokumine Alan Kawarai Lefor Tadao Ando Tomoko Yorozu Department of Pain Clinic NTT Medical Center TokyoHigashigotanda 141-8625TokyoJapan Department of Anesthesiology Hino Municipal HospitalTamadaira 191-0062TokyoJapan Department of Anesthesiology Kyorin University School of MedicineMitaka 181-8611TokyoJapan Department of Surgery Jichi Medical UniversityShimotsuke 329-0498TochigiJapan

BACKGROUND Anterior cutaneous nerve entrapment syndrome is defined as abdominal pain due to entrapped intercostal *** is the first report of a patient successfully treated for anterior cutaneous nerve entrapment syndrome after laparoscopic surgery with an ultrasound-guided rectus sheath *** rectus sheath block physically lysed adhesions and relieved pain from anterior cutaneous nerve entrapment *** SUMMARY The patient is a 44-year-old man who presented with severe left upper abdominal pain at an operative scar one month after laparoscopic ulcer *** and treatment were performed using an ultrasound-guided rectus sheath block with 0.1%lidocaine 20 *** pain was relieved after the *** diagnosis was anterior cutaneous nerve entrapment *** sheath block may be effective for patients with anterior cutaneous nerve entrapment *** Ultrasound-guided rectus sheath block is a promising treatment modality for patients with postoperative anterior cutaneous nerve entrapment syndrome due to adhesions.

关键词： Anterior cutaneous nerve entrapment syndrome Rectus sheath block Hydrodissection Laparoscopic surgery Case report

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Estrogen-mediated downregulation of HIF-1αsignaling in B lymphocytes influences postmenopausal bone loss

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Bone Research 2022年第2期10卷 326-337页

作者： Xianyi Meng Zhen Lin Shan Cao Iga Janowska koshiro Sonomoto Darja Andreev Knab Katharina Jinming Wen Karl Xaver Knaup Michael Sean Wiesener Gerhard Krönke Marta Rizzi Georg Schett Aline Bozec Department of Internal Medicine 3 Friedrich-Alexander-University Erlangen-Nürnberg(FAU)and Universitätsklinikum ErlangenErlangen 91054Germany Deutsches Zentrum fur Immuntherapie(DYI) Erlangen 91054Germany Department of Rheumatology and Clinical Immunology Faculty of MedicineMedical Center-University of FreiburgFreiburg 79106Germany Department of Internal Medicine 4 Friedrich-Alexander-University Erlangen-Nürnberg(FAU)and Universitätsklinikum ErlangenErlangen 91054Germany

In the bone marrow, B cells and bone-resorbing osteoclasts colocalize and form a specific microenvironment. How B cells functionally influence osteoclasts and bone architecture is poorly understood. Using genetically modified mice and highthroughput analyses, we demonstrate that prolonged HIF-1α signaling in B cells leads to enhanced RANKL production and osteoclast formation. In addition, deletion of HIF-1α in B cells prevents estrogen deficiency-induced bone loss in ***, estrogen controls HIF-1α protein stabilization through HSP70-mediated degradation in bone marrow B *** stabilization of HIF-1α protein in HSP70-deficient bone marrow B cells promotes RANKL production and *** of HSP70 expression by geranylgeranylacetone(GGA) administration alleviates ovariectomy-induced ***, RANKL gene expression has a positive correlation with HIF1 A expression in human B cells. In conclusion, HIF-1αsignaling in B cells is crucial for the control of osteoclastogenesis, and the HSP70/HIF-1α axis may serve as a new therapeutic target for osteoporosis.

关键词： mediated lymphocytes stabilization

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Zircon within chromitite requires revision of the tectonic history of the Eoarchean Itsaq Gneiss complex,Greenland

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Geoscience Frontiers 2023年第6期14卷 273-285页

作者： Hikaru sawada Tomoaki Morishita Adrien Vezinet Richard Stern Kenichiro Tani Ikuya Nishio Kanta Takahashi D.Graham Pearson Kristoffer Szilas Department of Earth System Science University of ToyamaToyamaJapan X-Star Japan Agency for Marine-Earth Science and Technology(JAMSTEC)KanagawaJapan Faculty of Geosciences and Civil Engineering Kanazawa UniversityKanazawaJapan Lamont-Doherty Earth Observatory Columbia UniversityPalisadesUSA Volcanoes and Earth’s Interior Research Center JAMSTECKanagawaJapan Department of Earth and Atmospheric Sciences University of AlbertaEdmontonCanada Canadian Centre for Isotopic Microanalysis University of AlbertaEdmontonCanada National Museum of Nature and Science TsukubaJapan Department of Geosciences and Natural Resource Management University of CopenhagenCopenhagenDenmark

The Ujaragssuit Nunat layered(UNL)unit in the Itsaq Gneiss Complex,west Greenland,has been consid-ered to contain one of the oldest chromitites on Earth based on~ca.4.1 Ga Hadean whole rock Pt-Os model ages and ca.3.81 Ga zircon U-Pb age of the surrounding *** study obtained zircon from the chromitite within this unit as well as granitoid sheets that intruded into the UNL ***-situ U-Pb-Hf-O isotope measurements were made on the *** from both the chromitite and the intrusive granitoids show concordant U-Pb ages of ca.2.97-2.95 *** contrast,Hf and 0 isotopic anal-yses indicate that zircons in the chromitites have a different origin from those in the intrusive *** from granitoids yielded Th/U ratios higher than 0.2,initial Hf isotope ratios of 0.2805-0.2807(i.e,initial:Hf value of-11 to-5),andδ^(18)O values of mostly 6.0‰-7.0‰,which are typical for felsic igneous rocks in Archean continental *** least altered zircons from a chromitite exhibited initial Hf isotope ratios of 0.28078-0.28084(i.e.,initial:Hf value of-1.1 to-0.4),close the chondritic value at ca.3.0 Ga and the depleted mantle at ca.3.2 *** zircons also haveδ^(18)O values of 4.2‰6.1‰which correspond to typical mantle *** other chromitite zircons yielded Th/U ratios lower than 0.1,and Hf and 0 isotopic compositions ranging between the least altered zircons and the intrusive granitoid *** results indicate that the zircons in the chromitites crystallized before or during the 2.97-2.95 Ga granitoid intrusion and most of the zircons were altered by subsequent ***,the present results suggest that zircons in the chromitites originally had depleted Hf iso-topic compositions at ca.3.2-3.0 *** can be explained by two different models of the evolution of the UNL *** is that if the UNL unit was formed at>3.81 Ga as previously thought,with the zircons in the chromitites subsequently being precipitated by ca.3.2-2.95 G

关键词： Archean Itsaq gneiss complex Ultramafic rock Metasomatism

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Molecular Phylogeny and Evolution of Two Rhacophorus Species Endemic to Mainland Japan

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Asian Herpetological Research 2019年第2期10卷 86-104页

作者： Masafumi MATSUI Yasuhiro KAWAHARA Kanto NISHIKAWA Seiji IKEDA koshiro ETO Yusuke MIZUNO Graduate School of Human and Environmental Studies Kyoto UniversityYoshida Nihonmatsu-choSakyo-kuKyoto 606-8501Japan Hagi City Museum Horiuchi 355HagiYamaguchi 758-0057Japan Hiroshima University Museum Kagamiyama 1-1-1Higashi Hiroshima CityHiroshima 739-8524Japan Kitakyushu Museum of Natural History and Human History Higashida 2-4-1Yahatahigashi-kuKitakyushuFukuoka 805-0071Japan Takahari 4-1002 Meito-kuNagoya 465-0061Japan

We conducted molecular phylogenetic analyses of Japanese Rhacophorus species, especially of R. schlegelii and R. arboreus from the mainland, based on samples encompassing their known distribution ranges, and discussed about evolutionary history of Rhacophorus species within Japan. The common ancestor of Japanese Rhacophorus, except for R. owstoni from southern Ryukyus, was estimated to have diverged from a lineage occurring mainly in China about 7 MYBP. Both R. schlegelii and R. arboreus are genetically largely divergent between regions of eastern and western Japan, and this seems to have been promoted mainly by retreat to refugia. Retreats of the two species to different refugia sometimes in the past seem to have led restricted distribution of R. schlegelii in eastern and R. arboreus in western Japan, and brought their intraspecific variation patterns in morphology and breeding habit.

关键词： glacial period mitochondrial DNA differentiation refugia Rhacophorus arboreus Rhacophorus schlegelii

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A case study of seismic response of earth embankment foundation on liquefiable soils

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Journal of Central South University 2009年第6期16卷 994-1000页

作者：黄雨 YASHIMA A sawada K 张锋 Department of Geotechnical Engineering Tongji University Key Laboratory of Geotechnical and Underground Engineering Ministry of EducationTongji University Department of Civil Engineering Gifu University Department of Civil Engineering Nagoya Institute of Technology

A case study of seismic response of an earth embankment foundation on liquefiable soils in Kansai area,western Japan was presented. Based on a calibrated cyclic elasto-plastic constitutive model for liquefiable sand and Biot dynamic coupled theory,the seismic analysis was carried out by using a dynamic effective stress finite element method under plane strain condition. A recent design study was illustrated in detail for a river earth embankment subjected to seismic excitation on the saturated deposits with liquefiable sands. Simulated results of the embankment foundation during liquefaction were obtained for acceleration,displacement,and excess pore water pressures,which were considered to yield useful results for earthquake geotechnical design. The results show that the foundation soil reaches a fully liquefied state with high excess pore pressure ratios approaching to 1.0 due to the earthquake shaking. At the end of the earthquake,the extensive liquefaction causes about 1.0 m lateral spreading at the toe and 60 cm settlement at the crest of the earth embankment.

关键词：地震响应地基土壤液化土堤案例超孔隙水压力岩土工程设计有限元方法

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