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presentation and surgical management of xanthogranulomatous cholecystitis

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Hepatobiliary & pancreatic Diseases International 2021年第2期20卷 117-127页

作者： Maximos Frountzas Dimitrios Schizas Efstathia Liatsou konstantinos p economopoulos Christina Nikolaou konstantinos G Apostolou konstantinos G Toutouzas Evangelos Felekouras First propaedeutic Department of Surgery Hippocration General HospitalNational and Kapodistrian University of AthensSchool of Medicine114 Vas.Sofias Ave.11527AthensGreece Laboratory of Experimental Surgery and Surgical Research National and Kapodistrian University of AthensSchool of Medicine15B Ag.Thoma Str.11527AthensGreece First Department of Surgery Laikon General HospitalNational and Kapodistrian University of AthensSchool of Medicine17 Ag.Thoma Str.11527AthensGreece Society of Junior Doctors Surgery Workgroup75 Mikras Asias Str.11527AthensGreece Department of Surgery Duke University Medical Center2301 Erwin RdDurhamNC 27707USA

Background:Xanthogranulomatous cholecystitis(XGC)is a rare benign chronic inflammatory disease of the gallbladder that often presents as cholecystitis and most of the times requires surgical *** addition,distinguishing XGC from gallbladder cancer preoperatively is still a *** aim of the present systematic review was to outline the clinical presentation and surgical approach of *** sources:The present systematic review was designed using the pRISMA and AMSTAR *** searched MEDLINE,Scopus,***,EMBASE,Cochrane Central Register of Controlled Trials(CENTRAL)and Google Scholar databases from inception until June ***:The laparoscopic cholecystectomy rate(34%)was almost equal to the open cholecystectomy rate(47%)for *** important conversion rate(35%)was observed as *** XGC cases treated by surgery were associated with low mortality(0.3%),limited intraoperative blood loss(58-270 m L),low complication rates(2%–6%),along with extended operative time(82.6–120 minutes for laparoscopic and 59.6–240 minutes for open cholecystectomy)and hospital stay(3–9 days after laparoscopic and 8.3–18 days after open cholecystectomy).Intraoperative findings during cholecystectomies for XGC included empyema or Mirizzi *** addition,complex surgical procedures,like wedge hepatic resections and bile duct excision were required during operations for ***:XGC seemed to be a rare,benign inflammatory disease that presents similar features as gallbladder *** mortality and complication rates of XGC were low,despite the complex surgical procedures that might be required in some cases.

关键词： Xanthogranulomatous cholecystitis Surgical management pathology postoperative complications

Acute esophageal necrosis: A systematic review and pooled analysis

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World Journal of Gastrointestinal Surgery 2020年第3期12卷 104-115页

作者： Dimitrios Schizas Nikoletta A Theochari konstantinos S Mylonas prodromos Kanavidis Eleftherios Spartalis Stamatina Triantafyllou konstantinos p economopoulos Dimitrios Theodorou Theodore Liakakos First Department of Surgery National and Kapodistrian University of AthensLaikon General HospitalAthens 11527Greece Department of Medicine Surgery Working GroupSociety of Junior DoctorsAthens 15122Greece Laboratory of Experimental Surgery and Surgical Research N.S.Christeas National and Kapodistrian University of AthensAthens 11527Greece First propedeutic Department of Surgery National and Kapodistrian University of AthensHippocration General HospitalAthens 11527Greece Department of Surgery Duke University Medical CenterDurhamNC 27708United States

BACKGROUND Acute esophageal necrosis(AEN)is a rare entity with multifactorial etiology,usually presenting with signs of upper gastrointestinal *** To systematically review all available data on demographics,clinical features,outcomes and management of this medical *** A systematic literature search was performed with respect to the pRISMA statement(end-of-search date:October 24,2018).Data on the study design,interventions,participants and outcomes were extracted by two independent *** Seventy-nine studies were included in this ***,114 patients with AEN were identified,of whom 83 were males and 31 *** patient age was 62.1±*** most common presenting symptoms were melena,hematemesis or other manifestations of gastric bleeding(85%).The lower esophagus was most commonly involved(92.9%).The most widely implemented treatment modality was conservative treatment(75.4%),while surgical or endoscopic intervention was required in 24.6%of the *** overall followup was 66.2±101.8 *** 29.9%of patients died either during the initial hospital stay or during the follow-up *** symptoms on presentation[Odds ratio 3.50(1.09-11.30),p=0.03]and need for surgical or endoscopic treatment[surgical:Odds ratio 1.25(1.03-1.51),p=0.02;endoscopic:Odds ratio 1.4(1.17-1.66),pplications.A sub-analysis separating early versus late cases(after 2006)revealed a significantly increased frequency of surgical or endoscopic intervention(9.7%vs 30.1%respectively,p=0.04)CONCLUSION AEN is a rare condition with controversial pathogenesis and unclear optimal *** the frequency of surgical and endoscopic intervention has increased in recent years,outcomes have remained the ***,further research work is needed to better understand how to best treat this potentially lethal disease.

关键词： Acute esophageal necrosis Black esophagus Acute necrotizing esophagitis

preventing pediatric cardiothoracic trauma:Role of policy and legislation

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World Journal of Cardiology 2018年第7期10卷 49-51页

作者： konstantinos S Mylonas pouya Hemmati Diamantis I Tsilimigras pavlos Texakalidis konstantinos p economopoulos pediatric Cardiology Working Group Society of Junior DoctorsAthens 15123Greece Department of Surgery Mayo ClinicRochesterMN 55902United States School of Medicine National and Kapodistrian University of AthensAthens 11527Greece pavlos Texakalidis Konstantinos P EconomopoulosSurgery Working GroupSociety of Junior DoctorsAthens 15123Greece School of Medicine Faculty of Health SciencesAristotle University of ThessalonikiThessaloniki 54621Greece Department of Surgery Duke University Medical CenterDurhamNC 27710United States

Data from the last 50 years suggest that pediatric pa-tients typically suffer cardiothoracic injuries following blunt traumatic force(70%) in the setting of either motor vehicle crashes(53.5%) or vehicle-pedestrian accidents(18.2%). penetrating trauma accounts for 30% of pediatric cardiothoracic injuries, half of which are gunshot wounds. Graduated driver licensing progr-ams, gun-control legislation, off-road vehicle regulation, initiatives such as "prevent the Bleed", as well as prof-essional society recommendations are key in preventing pediatric cardiothoracic injuries.

关键词： pediatric trauma Blunt cardiac trauma penetrating cardiac trauma Injury Children policy Legislation

History of the infantile hepatic hemangioma:From imaging to generating a differential diagnosis

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World Journal of Clinical pediatrics 2016年第3期5卷 273-280页

作者： Maria Gnarra Gerald Behr Alison Kitajewski June K Wu Sudha A Anupindi Carrie J Shawber Nick Zavras Dimitrios Schizas Chris Salakos konstantinos p economopoulos Vascular Biology program Department of SurgeryBoston Children's Hospital and Harvard Medical School Department of Radiology Columbia University Medical Center Department of Surgery Columbia University Medical Center Department of Radiology the Children's Hospital of PhiladelphiaUniversity of Pennsylvania Perelman School of Medicine Department of OB/GYN Columbia University Medical Center Department of pediatric Surgical "ATTIKO" General University Hospital Society of Junior Doctors Surgery Working Group Department of Surgery Massachusetts General HospitalHarvard Medical School

We aim to provide an up-to-date summary of infantile hepatic hemangioma(IHH) and its misnomers and to dialectically present the differential diagnosis of these rare entities of the *** peer-reviewed articles on hepatic infantile hemangiomas,published between 2000 and 2015,were reviewed for this *** is the most common hepatic vascular tumor in *** a liver mass is identified in an infant,the differential diagnosis ranges from vascular malformations to benign and malignant tumors including mesenchymal hamartoma,hepatoblastoma,metastatic neuroblastoma,so careful physical examination,imaging studies,and,if indicated,tumor markers and biopsy,are of pivotal importance to ascertain the correct *** the benign nature of IHHs,some of these lesions may demand medical and/or surgical intervention,especially for multiple and diffuse *** can include hepatomegaly,hypothyroidism and cardiac ***,a close follow-up is required until complete involution of the *** propose an algorithm to guide the physicians towards the proper management of hepatic lesions.

关键词： Hepatic hemangiomas Infant Children Vascular tumors

Desmoid tumor in a laparotomy scar in a child: Case report and brief literature review

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Open Journal of pediatrics 2013年第4期3卷 386-390页

作者： J. Skondras p. Valioulis D. papakonstantinou N. economopoulos A. Sourla N. Zavras 2nd Department of Radiology ATTIKO University Hospital Athens Greece 2nd pediatric Surgery Department “P&A Kyriakou” Children’s Hospital Athens Greece 3rd Department of General Surgery ATTIKO University Hospital Athens Greece Department of pathology Athens Medical Center Athens Greece pediatric Surgery Department Athens Medical Center Athens Greece

Desmoid tumors are rare neoplasms arising at the site of any fascia. Although histologically benign, they can cause local infiltration and they also carry a risk of recurrence. We describe the case of an 11-year-old girl who presented with a desmoid tumor at the site of an old trauma, and we briefly review the literature of this lesion.

关键词： Desmoid Tumor Laparaotomy Scar Children