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Subclavian Impella 5.0 to the rescue in a non-ST elevation myocardial infarction patient requiring unprotected left main rotablation: A case report

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World Journal of Cardiology 2020年第4期12卷 155-160页

作者： Vasileios Panoulas María Monteagudo-Vela konstantinos kalogeras Andre Simon Department of Cardiology Harefield HospitalRoyal Brompton and Harefield NHS Foundation TrustLondon UB96JHUnited Kingdom Cardiovascular Sciences National Heart and Lung InstituteImperial CollegeLondon SW72BUUnited Kingdom Department of Cardiothoracic Transplantation and Mechanical Circulatory Support Harefield HospitalRoyal Brompton and Harefield NHS Foundation TrustLondon UB96JHUnited Kingdom

BACKGROUND Often in patients with significant three-vessel or left main disease there is coexistent significant peripheral disease rendering them poor candidates for percutaneous left ventricular support during *** on the management of such cases is *** SUMMARY We describe a case of such a patient with critical distal left main disease and chronically occluded right coronary artery who presented with chest pain and a non-ST elevation myocardial infarction and had significantly impaired left ventricular *** the aid of our cardiothoracic surgeons a cut down subclavian Impella 5.0 was inserted and high risk rotablation percutaneous coronary intervention carried out *** This case highlights the need for cross-specialty collaborations in such high-risk cases were alternative access is needed for insertion of large bore mechanical circulatory support devices.

关键词： Impella Subclavian Rotablation Left main Percutaneous coronary intervention Case report

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Antithrombotic therapy in TAVI

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Journal of Geriatric Cardiology 2018年第1期15卷 66-75页

作者： Manolis Vavuranakis konstantinos kalogeras Angelos Michail Kolokathis Dimitrios Vrachatis Nikolaos Magkoutis Gerasimos Siasos Euaggelos Oikonomou Maria Kariori Theodoros Papaioannou Maria Lavda Carmen Moldovan Ourania Katsarou Dimitrios Tousoulis The First Department of Cardiology Hippokration Hospital Medical School National & Kapodistrian University of Athens Ilioupoli Greece

Transcatheter aortic valve implantation （TAVI） carries a significant thromboembolic and concomitant bleeding risk, not only during the procedure but also during the periprocedural period. Many issues concerning optimal antithrombotic therapy after TAVI are still under debate. In the present review, we aimed to identify all relevant studies evaluating antithrombotic therapeutic strategies in relation to clinical outcomes after the procedure. Four randomized control trials （RCT） were identified analyzing the post-TAVI antithrombotic strategy with all of them utilizing aspirin lifelong plus clopidogrel for 3-6 months. Seventeen registries have been identified, with a wide variance among them regarding baseline characteristics, while concerning antiplatelet therapy, clopidogrel duration was ranging from 3-12 months. Four non-randomized trials were identified, comparing single vs. dual antiplatelet therapy after TAVI, in respect of investigating thromboembolic outcome events over bleeding complications. Finally, limited data from a single RCT and a retrospective study exist with regards to anticoagulant treatment during the procedure and the optimal antithrombotic therapy when concomitant atrial fibrillation. In conclusion, due to the high risk and frailty of the treated population, antithrombotic therapy after TAVI should be carefully evaluated. Diminishing ischaemic and bleeding complications remains the main challenge in these patients with further studies to be needed in this field.

关键词： Antiplatelets Antithrombotic Bleeding Stroke Transcatheter aortic valve implantation

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A Method for Developing Seismic Intensity Maps from Twitter Data

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Journal of Civil Engineering and Architecture 2016年第7期10卷 839-852页

作者： Stathis G. Arapostathis Parcharidis Isaak Stefanakis Emmanuel Drakatos George kalogeras Ioannis Department of Geography Harokopio University Kallithea-Athens 17671 Greece Department of Geodesy and Geomatics Engineering University of New Brunswick Frederincton E3B EA3 Canada National Observatory of A them Athens 11810 Greece

Aim of this article, is to present a methodology for extracting macroseismic intensity information and producing seismic intensity maps from VGI （volunteered geographic information）. As a VGI source for obtaining and assessing macroseismic observations, the authors chose twitter. Our methodology is validated in two recent earthquakes occurred in Greece： the January 26, 2014 ML = 5.8 in Kefallinia, and the November 17, 2014 ML = 5.2 in Evoikos. Twitter data published within the first 6 h, 12 h, 24 h and 48 h after the earthquake occurrence were analyzed to develop seismic intensity maps. Those maps were evaluated through intensity maps for the same earthquakes, published by international institutes. Evaluation results provide a strong empiric evidence for the credibility of our methodology, the accuracy of the produced seismic intensity maps and accentuate VGI, generated by twitter, as an adequate alternative source for collecting macroseismic information.

关键词： Volunteered geographic information twitter seismic intensity intensity maps earthquakes.

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