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Fiber laser with random-access pulse train profiling for a photoinjector driver

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Photonics Research 2017年第4期5卷 293-298页

作者： EKATERINA I.GACHEvA ANATOLY K.POTEOMKIN SERGEY YU.MIRONOv vIKTOR v.ZELENOGORSKII EFIM A.KHAZANOv konstantin B.YUSHKOv ALEXANDER I.CHIZHIKOv vLADIMIR YA.MOLCHANOv Institute of Applied Physics of the Russian Academy of Sciences (IAP RAS) National University of Science and Technology "MISIS "

We report on the design and performance of a fiber laser system with adaptive acousto-optic macropulse control for a novel photocathode laser driver with 3D ellipsoidal pulse shaping. The laser system incorporates a threestage fiber amplifier with an integrated acousto-optical modulator. A digital electronic control system with feedback combines the functions of the arbitrary micropulse selection and modulation resulting in macropulse envelope profiling. As a benefit, a narrow temporal transparency window of the modulator, comparable to a laser pulse repetition period, effectively improves temporal contrast. In experiments, we demonstrated rectangular laser pulse train profiling at the output of a three-cascade Yb-doped fiber amplifier.

关键词： AOM Fiber laser with random-access pulse train profiling for a photoinjector driver

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切尔诺贝利事故清理工作者淋巴细胞的尾核

辐射研究与辐射工艺学报 2008年第6期26卷 371-373页

作者：李雨李智恒 v.Yu.kravtsov S.S.Aleksanin 第二军医大学海军医学系放射医学教研室 All-Russia Center of Emergency and Radiation Medicine 194044 St.PetersburgRussia

为了研究切尔诺贝利事故清理工作者和其他受照射人员外周血淋巴细胞,选取切尔诺贝利事故清理工作者和其他受照射人员作为试验组,采用常规方法取指尖外周血制备涂片,空气干燥,对氨基苯甲酸混合,Giemsa法染色,光镜下计数每人500个细胞样本... 详细信息

为了研究切尔诺贝利事故清理工作者和其他受照射人员外周血淋巴细胞,选取切尔诺贝利事故清理工作者和其他受照射人员作为试验组,采用常规方法取指尖外周血制备涂片,空气干燥,对氨基苯甲酸混合,Giemsa法染色,光镜下计数每人500个细胞样本,观察记录具有尾状突起细胞核发生率,进行统计学处理。未照射对照组的外周血淋巴细胞尾核发生率在0%～0.6%,平均值0.16。而大多数受照射对象都出现较多具有尾核的淋巴细胞。照射组的淋巴细胞出现尾核最大值是3.2%,平均值是0.50%。切尔诺贝利事故清理工作者的带尾核的淋巴细胞出现的几率显著高于对照组(p<0.01)。外周血淋巴细胞尾核可能是一种有意义的受照射标记物,受照射淋巴细胞尾核的异常出现可能起因于双着丝粒所形成的染色体桥的断裂。对于更加详尽地获取辐射生物效应信息,回顾性研究辐射剂量效应可能具有重要的理论和实践价值。

关键词：切尔诺贝利核事故辐射尾核

Biochar-induced changes in metal mobility and uptake by perennial plants in a ferralsol of Brazil’s Atlantic forest

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Biochar 2019年第3期1卷 309-324页

作者： konstantin von Gunten Magdalena Hubmann Robert Ineichen Yunhai Gao Konhauser OKurt Daniel SAlessi University of Alberta Earth and Atmospheric Sciences1-26 Earth Sciences BuildingEdmontonAB T6G 2E3Canada University of Alberta AgriculturalFood and Nutritional Science410 Agriculture/Forestry CentreEdmontonAB T6G 2P5Canada AgraDEço Rua do MundoParatyRJ 23970-000Brazil

Despite an abundance of short-term studies focusing on biochar’s effects on annual plants,the long-term effects of biochar on perennial plants and the effects of the biochar on the mobility and speciation changes of metals/metalloids not limited to main plant nutrients in soils are poorly *** study reports on the amelioration a sloped orthic ferralsol by biochar from Tibouchina wood and the resulting effects on perennial crops and microbiota,including a comprehensive analysis of metals/metalloids speciation *** were amended with biochar and urine-amended biochar(2 kg/m^(2))and were planted with papaya,banana,and *** and plant materials were analyzed using acid digestions,sequential extractions,and 16S rRNA gene *** applications led to decreased soil acidity,shifted the cation exchange capacity from being Al-influenced to being Mg/K/Ca-dominated,and elevated the concentrations of Mg,K,Ca,Zn,and Ba in *** exchangeable/acid-soluble fraction of Ca,P,and S notably *** soil microbial biome became more species rich and diverse in the biochar-amended *** benefited from biochar applications,demonstrating increased growth,which resulted in generally decreased concentrations of trace elements in most plant parts,however,with an increased total elemental *** amendment contributed to higher concentrations of P,S,and K in soils,but did not further increase plant *** was shown to be a promising soil amendment for agricultural use of orthic ferralsols of the Brazil’s Atlantic forest region,but the accumulation of potentially harmful metals needs to be considered.

关键词： Biochar in agriculture Agroforestry Ferralsol management Trace-metal speciation Biogeochemistry Plant metal uptake

Genetic link between saline and carbonatitic mantle fluids:The system NaCl-CaCO_(3)-MgCO_(3)±H_(2)O±Fe^(0) at 6 GPa

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Geoscience Frontiers 2022年第6期13卷 59-74页

作者： Anton Shatskiy Ivan v.Podborodnikov Anton v.Arefiev Altyna Bekhtenova konstantin D.Litasov vernadsky Institute of Geochemistry and Analytical Chemistry of the Russian Academy of Science Moscow 119991Russia vereshchagin Institute for High Pressure Physics of the Russian Academy of Science TroitskMoscow108840Russia

Melt inclusions in kimberlitic minerals and diamonds indicate that chlorides are important constituents of mantle carbonatite ***,alkaline chlorides are important constituents of saline high-density fluids(HDFs)found in diamonds from kimberlites and placers around the *** compositional variations suggest that saline and carbonatitic HDFs could be genetically ***,the essence of this link remains unclear owing to the lack of data on phase relations in the chloridecarbonate systems under *** we studied subsolidus and melting phase relations in the system NaCl–CaCO_(3)–MgCO_(3)at 6 GPa and 1000–1600℃using a Kawai-type multianvil *** found that at 1000℃,subsolidus assemblage consists of halite,magnesite,and *** higher temperatures,the stabilization of dolomite splits the subsolidus area into two partial ternary fields:halite+magnesite+dolomite and halite+dolomite+*** minimum on the liquidus surface corresponds to the halite-dolomite-aragonite ternary eutectic,situated at 1100℃.The eutectic melt has Ca#89 and contains 30 wt.%Na Cl(26 mol%2NaCl).The system has two ternary peritectics:halite+dolomite=magnesite+liquid located near the ternary eutectic and magnesite+dolomite=Mg-dolomite+liquid situated between 1300 and 1400℃.Although under dry conditions incipient melting yields carbonatedominated melt,the addition of water facilitates the fusion of Na Cl and expands the liquid field to Na Cl-rich compositions with up to 70 wt.%Na *** obtained results favor the idea that hydrous saline melts/fluids(brines)found as inclusions in diamonds could be a lower temperature derivative of mantle carbonatite melts and disagree with the hypothesis on chloride melt generation owing to the chloridecarbonate liquid immiscibility since no such immiscibility was *** also studied the interaction of the NaCl–CaCO_(3)–MgCO_(3)system with iron metal and found that carbonate reduction produces Cbearing species(Fe^(0)

关键词： Chloride Carbonate Halite Melting T-X diagram Earth’s mantle

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咖啡酸代谢物的抗肾炎活性分析

生物工程学报 2008年第12期24卷 2140-2141页

作者： Yulia v. Inyushkina konstantin v. Kiselev victor P. Bulgakov Biotechnology Department Institute of Biology and Soil Science Far East Branch of Russian Academy of Sciences Vladivostok 690022 Russia

在研究治疗肾功能紊乱植物的细胞培养时,建立了一个Eritrichium sericeum的E-4愈伤组织株系,发现此株系可产生大量的咖啡酸代谢物、(–)-rabdosiin(1.8%干重)和迷迭香酸(4.6%干重),通过诱导(–)-rabdosiin的含量提高至4.1%(干重)。将E-... 详细信息

在研究治疗肾功能紊乱植物的细胞培养时,建立了一个Eritrichium sericeum的E-4愈伤组织株系,发现此株系可产生大量的咖啡酸代谢物、(–)-rabdosiin(1.8%干重)和迷迭香酸(4.6%干重),通过诱导(–)-rabdosiin的含量提高至4.1%(干重)。将E-4愈伤组织喂服Masugi肾炎大鼠,结果发现,与对照组(未喂服E-4愈伤组织的Masugi肾炎大鼠)相比,处理组(喂服E-4愈伤组织)中的大鼠出现如下症状:尿多、排泄物中肌氨酸酐降低、尿蛋白水平降低;当对照组中所有大鼠都出现疼痛症状时,处理组中仍有约/4的大鼠表现出健康状况良好。以上结果表明,E-4株系具有缓解肾炎症状的潜在功能。此外,利用富含多酚的rolC转基因的细胞株系,研究了愈伤组织中咖啡酸代谢物的诱导合成机制。结果发现,在rloC转基因的***愈伤组织中,咖啡酸代谢物的高产与迷迭香酸生物合成中的关键基因CYP98A3的高表达有关。

关键词：咖啡酸代谢物细胞培养血管球性肾炎 CYP98

Epitaxial Ge Growth on Si(111) Covered with Ultrathin SiO<sub>2</sub>Films

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Journal of Surface Engineered Materials and Advanced Technology 2013年第3期3卷 195-204页

作者： Alexander A. Shklyaev konstantin N. Romanyuk Alexander v. Latyshev A. v. Rzhanov Institute of Semiconductor Physics of SB RAS Novosibirsk Russia A. v. Rzhanov Institute of Semiconductor Physics of SB RAS Novosibirsk Russia

The epitaxial growth of Ge on Si(111) covered with the 0.3 nm thick SiO2 film is studied by scanning tunneling microscopy. Nanoareas of bare Si in the SiO2 film are prepared by Ge deposition at a temperature in the range of 570℃-650℃ due to the formation of volatile SiO and GeO molecules. The surface morphology of Ge layers grown further at 360℃-500℃ is composed of facets and large flat areas with the Ge(111)-c(2 × 8) reconstruction which is typical of unstrained Ge. Orientations of the facets, which depend on the growth temperature, are identified. The growth at 250℃-300℃ produces continuous epitaxial Ge layers on Si(111). A comparison of the surface morphology of Ge layers grown on bare and SiO2-film covered Si(111) surfaces shows a significantly lower Ge-Si intermixing in the latter case due to a reduction in the lattice strain. The found approach to reduce the strain suggests the opportunity of the thin continuous epitaxial Ge layer formation on Si(111).

关键词： Ge/Si Heterostructures Epitaxial Growth Surface Morphology Scanning Tunneling Microscopy

Non-substituted fused bis-tetracene based thin-film transistor with self-assembled monolayer hybrid dielectrics

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Frontiers of Materials Science 2020年第3期14卷 314-322页

作者： Baolin Zhao Mikhail Feofanov Dominik Lungerich Hyoungwon Park Tobias Rejek Judith Wittmann Marco Sarcletti konstantin Amsharov Marcus Halik Organic Materials and Devices Institute of Polymer MaterialsDepartment of Materials ScienceFriedrich-Alexander-Universität Erlangen-NürnbergIZNF BuildingCauerstraße 391058ErlangenGermany Chair of Organic Chemistry II Friedrich-Alexander-Universität Erlangen-NürnbergNikolaus-Fiebiger-Str.1091058ErlangenGermany Molecular Technology Innovation Presidential Endowed Chair The University of Tokyo7-3-1 HongoBunkyo-ku113-0033TokyoJapan

Polycyclic aromatic hydrocarbons with zigzag peripheries are high perspective candidates for organic ***,large fused acenes are still poorly studied due to the tedious *** we report a non-substituted fused bistetracene DBATT(2.3,8.9-dibenzanthanthrene)as the semiconductor on low-voltage-driven organic thin-film *** systematic studies of thin-film growth on various self-assembled monolayer(SAM)modified gate dielectrics and the electrical performances were carried *** sub-monolayer of the semiconductor film shows larger island domains on the alkyl chain *** device exhibits the hole mobility of 0.011 cm2·v−1·s−1 with a current ratio of IonIIoff above 105.

关键词： fused bis-tetracene organic field-effect transistor contact resistance self-assembled monolayer

Immune Profile of COvID-19 Survivors and Contacts During 9 Months:A Cohort Study

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Infectious Diseases & Immunity 2023年第4期3卷 163-175页

作者： valentina v.Tatarnikova Natalya O.Kiseleva valentina I.Dubrovina vladimir A.vishnyakov Darya D.Bryukhova Anna B.Pyatidesyatnikova konstantin M.Korytov Munko B.Sharakshanov Sergey v.Balakhonov Irkutsk Antiplague Research Institute of Siberia and Far East of Rospotrebnadzor Irkutsk 664047Russia

Background:Severe acute respiratory syndrome coronavirus 2(SARS-Cov-2)causes a multi-organ systemic damage that can lead to long-term *** is known about the possible long-term effects of COvID-19 on circulating leukocyte kinetics and functional T-cell activity after *** investigate immune system changes,we designed a cohort ***:volunteer screening and sample collectionwere performed at the Irkutsk Research Anti-Plague Institute of ***-four volunteers who have had COvID-19(recovered volunteers(Rvs))betweenMay 2020 andMay 2021,33 volunteers who had been in contact with COvID-19 patients(contact volunteers(Cvs))within the family setting but had not become ill,and 47 healthy volunteers(Hvs)participated in the *** performed immunophenotyping of peripheral blood cells using flow *** was tested for SARS-Cov-2 anti-nucleocapsid immunoglobulin G antibodies by enzyme-linked immunosorbent assay(Ab(+),people with specific anti-N antibodies to SARS-Cov-2;Ab(−),people without specific antibodies).Results:There were no serious disturbances in the internal environment of the body in Rvs and *** the evaluation of the general state of the immune system,the most informative indicator was the index of the ratio of neutrophils to bloodmonocytes–decreased on the 1st terms of observation(1 and 3 months post-symptom onset(PSO)/post-contact onset(PCO)),on average,1.3 times compared with Hvs(8.6%(7.5%–10.5%),Pvered by the 6th month of *** of the cells responsible for the development of the adaptive immune response was noted only in Rvs–increased B-lymphocyte content(Hvs,9.1%(6.4%–10.2%))and immunoregulatory index ratio(Hvs,1.6%(1.2%–2.1%))due to redistribution of T-helper and cytotoxic T cells throughout the follow-up period by an average of 1.2-fold compared with Hvs(Pver,Cvs with specific antibodies to SARS-Cov-2 N-protein also had an increased proportion of CD3−CD19+c

关键词： COvID-19 Flow cytometry Immunity Specific IgG T cells B cells

IFIH1 and DDX58 gene variants in pediatric rheumatic diseases

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World Journal of Clinical Pediatrics 2023年第3期12卷 107-114页

作者： Rinat Raupov Evgeny Suspitsin konstantin Belozerov Tatiana Gabrusskaya Mikhail Kostik Department of Pediatry Saint-Petersburg State Pediatric Medical UniversitySaint-Petersburg 194100Russia Department of Genetics Saint-Petersburg State Pediatric Medical UniversitySaint-Petersburg 194100Russia Department of Gastrointestinal Diseases Saint-Petersburg State Pediatric Medical UniversitySaint-Petersburg 194100Russia

BACKGROUND The IFIH1 gene codes the MDA5 protein and the DDX58 gene codes the RIG-I *** proteins are parts of the interferon(IFN)I signaling pathway and are responsible for antiviral defense and innate immune ***1 and DDX58 polymorphisms are associated with a spectrum of autoimmune *** gain-of-function IFIH1 mutations have been found in Singleton-Merten and Aicardi-Goutières syndrome,while DDX58 mutation can cause atypical Singleton-Merten *** To characterize children with pediatric rheumatic diseases(PRD)carrying DDX58 or IFIH1 *** Clinical exome sequencing was performed on 92 children with different ***1 and DDX58 variants have been detected in 14 ***-I score has been analyzed and the clinical characteristics of patients have been *** A total of seven patients with systemic lupus erythematosus(SLE)(n=2),myelodysplastic syndrome with SLE features at the onset of the disease(n=1),mixed connective tissue disease(MCTD)(n=1),undifferentiated systemic autoinflammatory disease(uSAID)(n=3)have 5 different variants of the DDX58 gene.A common non-pathogenic variant p.D580E has been found in five children.A rare variant of uncertain significance(vUS)p.N354S was found in one patient with uSAID,a rare likely non-pathogenic variant p.E37K in one patient with uSAID,and a rare likely pathogenic variant ***864fs in a patient with *** IFN-I score was detected in 6 of 7 patients with DDX58 *** patients had six different IFIH1 *** were presented with uSAID(n=2),juvenile dermatomyositis(JDM)(n=1),SLElike disease(n=1),Periodic fever with aphthous stomatitis,pharyngitis,and adenitis syndrome(n=1),and systemic onset juvenile idiopathic arthritis(n=1).Three patients have vUS p.E627X,one patient has benign variant *** vUS p.R595H was detected in the JDM *** rare vUS p.L679Ifs*2 and previously not reported variant p.v599Ffs*5 were detected in the patient with uS

关键词： IFIH1 DDX58 Undifferentiated systemic autoinflammatory disease Systemic lupus erythematosus Interferon-I score©The Author(s)2023.Published by Baishideng