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Nutritional issues in patients with obesity and cirrhosis

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World Journal of Gastroenterology 2018年第30期24卷 3330-3346页

作者： Luigi Schiavo Luca Busetto Manuela Cesaretti Shira Zelber-Sagi Liat deutsch Antonio Iannelli Department of Translational Medical Science University of Campania“Luigi Vanvitelli”Naples 80131Italy Ⅸ Division of General Surgery Vascular Surgery and Applied BiotechnologyNaples University PoliclinicNaples 80131Italy Department of Medicine University of PaduaPadua 35128Italy Center for the Study and the Integrated Management of Obesity University Hospital of PaduaPadua 35128Italy Department of HPB Surgery and Liver Transplantation Hopital BeaujonAP-HPClichy 92110France Department of Nanophysics Italian Institute of TechnologyGenova 16163Italy School of Public Health University of HaifaHaifa 3498838Israel Department of Gastroenterology and Liver disease Tel Aviv Medical Center62431Tel-Aviv 62431Israel The Sackler Faculty of Medicine Tel-Aviv UniversityTel-Aviv 62431Israel Digestive Unit Archet 2 HospitalUniversity Hospital of NiceF-06202NiceFrance Inserm U1065Team 8“Hepatic complications of obesity”Nice F-06204France University of Nice Sophia-Antipolis Nice F-06107France

Obesity and metabolic syndrome are considered as responsible for a condition known as the non-alcoholic fatty liver disease that goes from simple accumulation of triglycerides to hepatic inflammation and may progress to *** with obesity also have an increased risk of primary liver malignancies and increased body mass index is a predictor of decompensation of liver *** obesity confers a risk of physical impairment and disability that is significantly higher than the risk induced by each of the two conditions alone as it has been shown to be an independent risk factor for chronicliver disease in patients with obesity and a prognostic negative marker for the evolution of liver cirrhosis and the results of liver *** patients with obesity are at high risk for depletion of various fat-soluble,water-soluble vitamins and trace elements and should be supplemented ***,physical activity and protein intake should be carefully monitored in these fragile patients according to recent *** surgery is sporadically used in patients with morbid obesity and cirrhosis also in the setting of liver *** risk of sarcopenia,micronutrient status,and the recommended supplementation in patients with obesity and cirrhosis are discussed in this ***,the indications and contraindications of bariatric surgery-induced weight loss in the cirrhotic patient with obesity are discussed.

关键词： obesity cirrhosis sarcopenia malnutrition bariatric surgery

Emergency department targeted screening for hepatitis C does not improve linkage to care

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World Journal of Gastroenterology 2020年第32期26卷 4878-4888页

作者： Inbal Houri Noya Horowitz Helena Katchman Yael Weksler Ofer Miller Liat deutsch Oren Shibolet Department of Gastroenterology and Hepatology Tel-Aviv Medical CenterTel-Aviv 6423906Israel Sackler Faculty of Medicine Tel-Aviv UniversityTel-Aviv 6997801Israel

BACKGROUND Hepatitis C virus(HCV)infection is a leading cause of chronic liver disease *** treatments for HCV revolutionized management and prompted the world health organization to set the goal of viral elimination by *** developments strengthen the need for HCV screening in order to identify asymptomatic carriers prior to development of chronic liver disease and its *** screening strategies have been attempted,most targeting high-risk *** studies focusing on patients arriving at emergency departments showed a higher prevalence of HCV compared to the general *** To identify previously undiagnosed HCV carriers among high risk emergency room attendees and link them to care for anti-viral *** In this single center prospective study,persons visiting the emergency department in an urban hospital were screened by a risk factor-specific *** risk factors screened for were exposure to blood products or organ transplantation before 1992;origins from countries with high prevalence of HCV;intravenous drug use;human immunodeficiency virus carriers;men who have sex with men;those born to HCV-infected mothers;prior prison time;and chronic kidney *** with at least one risk factor were tested for HCV by serum for HCV antibodies,a novel oral test from saliva(OraQuick®)or *** Five hundred and forty-one participants had at least one risk factor and were tested for *** four percent of all study participants had only one risk *** five percent of participants underwent OraQuick®testing,34%were tested for serum anti-HCV antibodies,and 25%had both tests.3.1%of patients(17/541)had a positive result,compared to local population incidence of 1.96%.Of these,82%were people who inject drugs(current or former),and 64%served time in *** patient had a negative HCV-RNA,and two patients died from non-HCV related *** review of past medical records,12 patients w

关键词： Screening Emergency departments Israel Saliva Hepatitis C Liver

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欧洲计划建造科技巴别塔

商业周刊（中文版） 2022年第13期 14-16页

作者： Jillian deutsch 程玺(译) 不详

任何欧洲人,只要有Gmail账户,都可以向仍在使用Hotmail的朋友发邮件,但无法通过WhatsApp向朋友的iMessage发消息。这似乎没什么大不了,但欧盟立法者认为此事足够严重,并决定在7月初由欧盟正式批准的里程碑新规《数字市场法》(DMA)中解... 详细信息

任何欧洲人,只要有Gmail账户,都可以向仍在使用Hotmail的朋友发邮件,但无法通过WhatsApp向朋友的iMessage发消息。这似乎没什么大不了,但欧盟立法者认为此事足够严重,并决定在7月初由欧盟正式批准的里程碑新规《数字市场法》(DMA)中解决该问题。下一步欧洲理事会主席和欧洲议会议长将分别签署这项法律,并在颁布后6个月生效实施。

关键词：欧洲理事会欧洲议会巴别塔 Hotmail DMA 欧盟

VLAN近况细说——Cabletron公司亚太区培训总监Gene deutsch先生

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微电脑世界 1997年第9期 21-22页

作者： Gene deutsch Cabletron系统公司

随着网络的不断增长,各公司已开始限制通信流的方法,VLAN(虚拟局域网络)正逐渐成为企业连网的关键部分。当这些新的大型网络在各城市和各洲之间跨接宽域路时,一般在服务器、路由器和其他网络节点间结送的、定期的管理通信流可能会产生... 详细信息

随着网络的不断增长,各公司已开始限制通信流的方法,VLAN(虚拟局域网络)正逐渐成为企业连网的关键部分。当这些新的大型网络在各城市和各洲之间跨接宽域路时,一般在服务器、路由器和其他网络节点间结送的、定期的管理通信流可能会产生一些消耗钱财和吸收带宽的通信流,它们对网络的生产力会产生影响。VLAN则可限制这种通信流及带宽需求。VLAN的好处在被人们接受,目前提供VLAN技术的厂商包括CISCO、3COM、Cabletron、Bay、Networks、Newbridge和DEC等厂商。来自评测机构的结果表明,Cabletron在VLAN技术方面似乎处于领先的地位,它的解决方案与其他厂商的不同在哪里呢?借Cabletron总公司高层技术专家来京之际,记者请他简述了VLAN技术的新进展和Ca+bletron的技术优势。

关键词： VLAN Cabletron Gene deutsch 端口镜像路由器

Darwin and the cirripedes: Insights and dreadful blunders

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Integrative Zoology 2009年第3期4卷 316-322页

作者： Jean S.deutsch UMR 7622 Developmental Biology Pierre and Marie Curie University(Paris 6)

Charles Darwin’s favorite animals were cirripedes(barnacles).Indeed,he worked intensively on cirripedes during the years he was maturing his thoughts regarding his theory,which eventually led to the publication of The Origin of *** I present some of Darwin’s achievements in the morphology,systematics and biology of these small marine invertebrates,and also,in light of our present knowledge,some mistakes he made.

关键词： cirripedes Darwin homology.

基于储层静态地质参数的一种随机建模结果排序方法

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石油学报 2010年第3期31卷 445-448页

作者：李少华张昌民 Clayton V. deutsch 长江大学地球科学学院湖北荆州434023 阿尔伯塔大学计算地质统计学中心

储层随机建模可以产生大量实现,而油藏数值模拟由于计算量大,通常只能对非常有限的实现进行模拟计算。随机选择实现常常会导致过于悲观或过于乐观的模拟结果,并且无法合理评价地质模型所包含的不确定性。利用与数模响应密切相关的静态... 详细信息

储层随机建模可以产生大量实现,而油藏数值模拟由于计算量大,通常只能对非常有限的实现进行模拟计算。随机选择实现常常会导致过于悲观或过于乐观的模拟结果,并且无法合理评价地质模型所包含的不确定性。利用与数模响应密切相关的静态地质指标,如连通原油体积对实现进行排序,然后选择典型的实现进行数模,较好地解决这一问题。但是,该指标没有考虑含油网格与生产井之间的距离及渗透率大小,而这两个参数对于流体流动有着重要的控制作用。在连通原油体积的基础上提出了一种新的排序指标。该指标在计算连通原油体积的公式上增加了网格与生产井之间的距离和渗透率两个影响因子。通过实例对这两种指标进行了对比研究,新指标更好地反映了不同实现的差别。

关键词：油藏数值模拟随机建模连通原油体积流体流动静态地质参数排序指标

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Matter and Radiation at Extremes 2019年第3期4卷 1-17页

作者： C.deutsch Laboratoire de Physique des Gaz et Plasmas CNRSUniversite Paris-SudUniversite Paris-Saclay91405 OrsayFrance

Correlated ion stopping arising from an intense cluster ion beam(CIB)interacting with an ultradense plasma target of relevance to inertial confinement fusion(ICF)is first investigated in a two-body approximation in an arbitrarily degenerate electron fluid *** specific advantages of CIB-driven ICF are first demonstrated through 1D simulations,highlighting the very fine focusing of the ion beam on the target ***,theN-body configurations of ion debris resulting from the impact of heavy cluster ions are determined in terms of their specific *** validities of the usual assumptions of equal ion fragment charge and negligible coupling between stopping and Coulomb explosion are assessed.

关键词： cluster negligible debris

Increased fibrosis progression rates in hepatitis C patients carrying the prothrombin G20210A mutation

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World Journal of Gastroenterology 2011年第45期17卷 5007-5013页

作者： Nitsan Maharshak Philippe Halfon Varda deutsch Hava Peretz Shlomo Berliner Sigal Fishman Shira Zelber-Sagi Uri Rozovski Moshe Leshno Ran Oren Department of Gastroenterology and Liver diseases Tel Aviv Sourasky Medical Center aff iliated to the Sackler School of Medicine Tel Aviv University Department of Virology Laboratoire Alphabio 23 Rue de Friedland Hpital Ambroise Paré The Hematology Institute Tel Aviv Sourasky Medical Center affi liated to the Sackler School of Medicine Tel Aviv University Clinical Biochemistry Laboratory Tel Aviv Sourasky Medical Center affiliated to the Sackler School of Medicine Tel Aviv University Internal Medicine "E" Tel Aviv Sourasky Medical Center affi liated to the Sackler School of Medicine Tel Aviv University

AIM: To examine whether hepatitis C virus (HCV)-infected patients who carry hypercoagulable mutationssuffer from increased rates of liver fi brosis. METHODS: We analyzed DNA samples of 168 HCV patients for three common hypercoagulable gene mutations: prothrombin 20210 (PT20210), factor V Leiden (FV Leiden) and methylene tetrahydrofolate reductase (MTHFR). The patients were consecutively recruited as part of the prospective "Fibroscore Study" in France. The effect of the various mutations on the rate of fi-brosis was analyzed statistically and was correlated with epidemiological, clinical and biochemical data such as grade and stage of liver biopsies, patients' risk factors for liver cirrhosis, and timing of infection. RESULTS: Fifty two of the patients were categorized as "fast fi brosers" and 116 as "slow fi brosers"; 13% of the "fast fi brosers" carried the PT20210 mutation as compared with 5.5% of the "slow fi brosers", with an odds ratio of 4.76 (P = 0.033; 95% CI: 1.13-19.99) for "fast" liver fibrosis. Carriage of MTHFR or FV Leiden mutations was not associated with enhanced liver fi brosis. CONCLUSION: Carriage of the PT20210 mutation is related to an increased rate of liver fi brosis in HCV patients.

关键词：丙型肝炎病毒基因突变凝血酶原肝纤维化患者亚甲基四氢叶酸还原酶 MTHFR基因感染时间

Poor Sleep Can Be Deadly for Elderly

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当代外语研究 2003年第3期 15-16页

作者： Nancy deutsch 李缀野

选注者言:文章的标题就警告我们,老人的睡眠事关重大。本文澄清了对老人的睡眠的传统误解,比如:older people need less sleep or shouldn’t be concerned ifthey have sleep problems.本文还劝告老人:… people who seem to sleep wel... 详细信息

选注者言:文章的标题就警告我们,老人的睡眠事关重大。本文澄清了对老人的睡眠的传统误解,比如:older people need less sleep or shouldn’t be concerned ifthey have sleep problems.本文还劝告老人:… people who seem to sleep wellshould work on improving their sleep habits.有些小建议对老人也可参考:Don’tdo work in bed,and no nappingduring the day.你若是年轻读者,请把这些内容介绍给你们年迈的父母吧!

关键词： Poor Sleep Can Be Deadly for Elderly Be

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