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Standardized ileal digestible lysine requirements based on growth performance and histochemical characteristics of male broilers from 10 to 21 d of age

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Animal Nutrition 2023年第1期12卷 145-150页

作者： Su Hyun An Boin lee Young Min Choi Changsu kong Department of Animal Science and Biotechnology Kyungpook National University37224SangjuRepublic of Korea Department of Animal Science Kyungpook National University37224SangjuRepublic of Korea

The growth performance and histochemical characteristics of breast muscle fibers were used to estimate the standardized ileal digestible(SID)Lys requirements for 10-to 21-d-old male *** hundred and sixty 10-d-old Ross 308 broilers(290±16.6 g)were allocated to 6 diets in a randomized complete block design with 6 replicate cages per treatment and 10 birds per *** 6 experimental diets were formulated to contain equally spaced increasing levels of SID Lys from 0.86%to 1.36%.The data were analyzed using the MIXED procedure of *** Lys requirements were estimated by the NLIN procedure of *** increase in dietary SID Lys from 0.86%to 1.36%resulted in a quadratic increase(P<0.05)in body weight gain(BWG),gain to feed ratio(G:F),breast weight,muscle cross-sectional area(MCSA),and fiber *** SID Lys requirements based on the one-slope broken-line,quadratic line,the first intercept between the plateau of the one-slope broken-line and quadratic-line models and 95%of the upper asymptote of the quadratic-line model were estimated to be 1.01%,1.19%,1.08%,and 1.13%for BWG,1.06%,1.22%,1.11%,and 1.16%for G:F,1.10%,1.29%,1.19%,and 1.22%for breast weight,1.06%,1.22%,1.12%,and 1.16%for MCSA,and 1.14%,1.22%,1.16%,and 1.16%for breast muscle fiber area,*** was concluded that the SID Lys requirements for broilers at the age of 10 to 21 d depended on the response variables used for estimation,and that histochemical characteristics of breast muscle fibers could be good indicators for estimating SID Lys requirements.

关键词： Requirement Lysine Growth performance Muscle fiber characteristics Broiler chicken

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K2Ti6O13 Nanoparticle-Loaded Porous rGO Crumples for Supercapacitors

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Nano-Micro Letters 2020年第1期12卷 115-123页

作者： Chongmin lee Sun Kyung Kim Hankwon Chang hee Dong Jang Department of Nanomaterials Science and Engineering University of Science and TechnologyYuseong‑guDaejeon 34113Republic of Korea Resources Utilization Research Center Korea Institute of Geoscience and Mineral ResourcesYuseong‑guDaejeon 34132Republic of Korea

One-dimensional alkali metal titanates containing potassium,sodium,and lithium are of great concern owing to their high ion mobility and high specific surface *** those titanates are combined with conductive materials such as graphene,carbon nanotube,and carbon nanofiber,they are able to be employed as efficient electrode materials for *** hexa-titanate(K2Ti6O13,KTO),in particular,has shown superior electrochemical properties compared to other alkali metal titanates because of their large lattice parameters induced by the large radius of potassium ***,we present porous rGO crumples(PGC)decorated with KTO nanoparticles(NPs)for application to *** KTO NP/PGC composites were synthesized by aerosol spray pyrolysis and post-heat *** NPs less than 10 nm in diameter were loaded onto PGCs ranging from 3 to 5μ*** porous structure of the composites was obtained by the activation of rGO by adding an excessive amount of KOH to the *** KTO NP/PGC composite electrodes fabricated at the GO/KOH/TiO2 ratio of 1:3:0.25 showed the highest performance(275 F g−1)in capacitance with different KOH concentrations and cycling stability(83%)after 2000 cycles at a current density of 1 A g−1.

关键词： Potassium hexa-titanate Porous graphene crumples Supercapacitors

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Ecotoxicity evaluation of Cu-and Fe-CNT complexes based on the activity of bacterial bioluminescence and seed germination

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Journal of Environmental Sciences 2018年第5期30卷 198-205页

作者： In Chul kong Kyung Seok Ko Mun Hui lee Ji Hwoan lee Young-Hwan Han Department of Environmental Engineering Yeungnam UniversityGyungsan 38541Republic of Korea Geologic Environment Division Korea Institute of Geoscience and Mineral Resources(KIGAM)Daejeon 34132Republic of Korea School of Materials Science and Engineering Yeungnam University Gyungsan 38541Republic of Korea International School of Materials Science and Engineering Wuhan University of TechnologyWuhan 430079China

The toxic effects of the composites of Fe^0 and Cu^0 with different percentages of CNTs were examined based on the activity of bacterial bioluminescence and seed germination. In terms of the EC50 values, the toxic effects of Cu^0 on bacterial bioluminescence and seed germination were approximately 2 and 180 times greater than that of Fe^0, respectively. The toxicity increased with increasing CNT content in the Cu-CNT mixtures for both organisms,whereas opposite results were observed with Fe-CNT mixtures. The mean toxic effects of Cu-CNT（6%） were approximately 1.3–1.4 times greater than that of Cu-CNT（0%）, whereas the toxic effects of Fe-CNT（6%） were approximately 2.1–2.5 times lower than that of Fe-CNT（0%） for both the bioluminescence activity and seed germination. The causes of this phenomenon are unclear at this point. More research will be needed to elucidate the mechanism of the toxicity of nano-mixture materials and the causes of the different patterns of toxicity with Cu-and Fe-CNT mixtures.

关键词： Metal-CNT complex Bioluminescence Seed germination Toxic effect

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Properties of multilayer gallium and aluminum doped ZnO(GZO/AZO) transparent thin films deposited by pulsed laser deposition process

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Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 96-99页

作者： Jin-Hyun SHIN Dong-Kyun SHIN hee-Young lee Jai-Yeoul lee Department of Materials Engineering Yeungnam University

Multilayer gallium and aluminum doped ZnO （GZO/AZO） films were fabricated by alternative deposition of Ga-doped zinc oxide（GZO） and Al-doped zinc oxide（AZO） thin film by using pulsed laser deposition（PLD） process. The electrical and optical properties of these GZO/AZO thin films were investigated and compared with those of GZO and AZO thin films. The GZO/AZO （1：1） thin film deposited at 400 ~C shows the electrical resistivity of 4.18 x 10 4 ~.cm, an electron concentration of 7.5 x 1020/cm3, and carrier mobility of 25.4 cm2/（V.s）. The optical transmittances of GZO/AZO thin films are over 85%. The optical band gap energy of GZO/AZO thin films linearly decreases with increasing the AI ratio.

关键词： multilayer thin films Ga-doped zinc oxide Al-doped zinc oxide pulsed laser deposition

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Successful treatment of relapsed acute promyelocytic leukemia with arsenic trioxide in a hemodialysis-dependent patient: A case report

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World Journal of Clinical Cases 2020年第21期8卷 5347-5352页

作者： hee Jeong lee Sang-Gon Park Department of Hemato-Oncology Chosun University HospitalGwang-ju 501-717South Korea Department of Internal Medicine Hemato-oncologyChosun University HospitalGwangju 61453South Korea

BACKGROUND Arsenic trioxide(ATO)is recommended for patients who do not achieve molecular remission or who have molecular or morphologic ***,there are no guidelines for adjusting ATO dosage in patients with severe renal failure or on ***,we report the successful treatment of relapsed acute promyelocytic leukemia(APL)in a patient on hemodialysis with ATO single agent and review the cases in *** SUMMARY A 46-year-old woman who has been on hemodialysis to chronic glomerulonephritis for 15 years visited our hospital for *** had been seen for pancytopenia 3 years ago and had been diagnosed with *** also received chemotherapy for APL but unfortunately was lost to follow-up after her second consolidation *** was noted to have pancytopenia by her nephrologist during hemodialysis 1 mo *** marrow biopsy and reverse transcriptase-polymerase chain reaction(RT-PCR)tests revealed a diagnosis of relapsed *** for relapsed APL with ATO single agent was started and she achieved molecular remission after administering 24 doses of *** far,four consolidation therapies have been performed with the ATO single agent,and,to date,the molecular remission has been maintained as negative promyelocytic leukemia/retinoic acid receptor-αfusion gene as confirmed by RTPCR testing for two *** This is a rare case of relapsed APL successfully treated with the single agent ATO in a patient on hemodialysis.

关键词： Arsenic trioxide Acute promyelocytic leukemia Pancytopenia Hemodialysis Promyelocytic leukemia/retinoic acid receptor-αfusion gene Case report

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A Novel Features Prioritization Mechanism for Controllers in Software-Defined Networking

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Computers, Materials & Continua 2021年第10期69卷 267-282页

作者： Jehad Ali Byungkyu lee Jimyung Oh Jungtae lee Byeong-hee Roh Department of Computer Engineering and Department of AI Convergence Network Ajou UniversitySuwon16499Korea LIG Next1 Co.Ltd. Seongnam13488Korea Department of Software and Computer Engineering Ajou UniversitySuwon16499Korea

The controller in software-defined networking(SDN)acts as strategic point of control for the underlying *** controllers are available,and every single controller retains a number of features such as the OpenFlow version,clustering,modularity,platform,and partnership support,*** are regarded as vital when making a selection among a set of *** such,the selection of the controller becomes a multi-criteria decision making(MCDM)problem with several ***,an increase in this number will increase the computational complexity of the controller selection ***,the selection of controllers based on features has been studied by the ***,the prioritization of features has gotten less ***,several features increase the computational complexity of the selection *** this paper,we propose a mathematical modeling for feature prioritization with analytical network process(ANP)bridge model for SDN *** results indicate that a prioritized features model lead to a reduction in the computational complexity of the selection of SDN *** addition,our model generates prioritized features for SDN controllers.

关键词： Software-defined networking controllers feature-based selection quality-of-service analytical network process analytical hierarchy process

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A practical guide to pharmaceutical polymorph screening & selection

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Asian Journal of Pharmaceutical Sciences 2014年第4期9卷 163-175页

作者： Eun hee lee College of Pharmacy Korea University2511 Sejong-roSejong 339-700Republic of Korea

Prevalence and importance of polymorphism occurring in pharmaceutical compounds are well *** is of great importance to prepare and select the right form from the beginning during drug discovery and *** review introduces the basic concepts of“What is polymorphism?”,addresses a fundamental question of“Why do polymorphs form?”,and provides practical guidelines of“How to prepare polymorphs?”“How to evaluate the relative thermodynamic stability between polymorphs?”,and“How to analyze polymorphs?”.Moreover,case studies of pharmaceutically important polymorphs are provided.

关键词： Polymorphs Polymorph screening Polymorph selection Polymorph preparation

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Chronic liver disease is universal in children with biliary atresia living with native liver

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World Journal of Gastroenterology 2017年第43期23卷 7776-7784页

作者： Way Seah lee Sik Yong Ong hee Wei Foo Shin Yee Wong Chen Xi kong Ru Bin Seah Ruey Terng Ng Department of Paediatrics University Malaya Medical Centre Paediatrics and Child Health Research Group University Malaya

AIM To examine the medical status of children with biliary atresia(BA) surviving with native *** In this cross-sectional review,data collected included complications of chronic liver disease(CLD)(cholangitis in the preceding 12 mo,portal hypertension,variceal bleeding,fractures,hepatopulmonary syndrome,portopulmonary hypertension) and laboratory indices(white cell and platelet counts,total bilirubin,albumin,international normalized ratio,alanine aminotransferase,aspartate aminotransferase,γ-glutamyl transpeptidase). Ideal medical outcome was defined as absence of clinical evidence of CLD or abnormal laboratory indices. RESULTS Fifty-two children [females = 32,62%; median age 7.4 years,n = 35(67%) older than 5 years] with BA(median age at surgery 60 d,range of 30 to 148 d) survived with native liver. Common complications of CLD noted were portal hypertension(40%,n = 21; 2 younger than 5 years),cholangitis(36%) and bleeding varices(25%,n = 13; 1 younger than 5 years). Fifteen(29%) had no clinical complications of CLD and three(6%) had normal laboratory indices. Ideal medical outcome was only seen in 1 patient(2%). CONCLUSION Clinical or laboratory evidence of CLD are present in 98% of children with BA living with native livers after hepatoportoenterostomy. Portal hypertension and variceal bleeding may be seen in children younger than 5 years of age,underscoring the importance of medical surveillance for complications of BA starting at a young age.

关键词： Biliary atresia Medical status Chronic liver disease

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Improved tensile properties of AZ31 Mg alloy subjected to various caliber-rolling strains

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Journal of Magnesium and Alloys 2019年第3期7卷 381-387页

作者： Jeong Hun lee Byung Je Kwak Taein kong Sung Hyuk Park Taekyung lee Advanced Forming Process R&D Group Korea Institute of Industrial TechnologyUlsan 44413Republic of Korea School of Mechanical Engineering Pusan National UniversityBusan 46241Republic of Korea School of Materials Science and Engineering Kyungpook National UniversityDaegu 41566Republic of Korea

A multi-pass caliber rolling has attracted attentions as an alternative to severe plastic deformation *** present study enhanced strength and ductility of AZ31 Mg alloy simultaneously through the application of caliber *** improving trends in tensile properties were interpreted with various caliber-rolling *** oval/circular-shaped calibers imposed a high plastic strain at the center of crosssection,leading to effective grain refinement to submicron *** work also confirmed the texture randomizing effect of caliber *** microstructural evolutions gave rise to the fabrication of high-strength ***,the caliber-rolled AZ31 Mg alloys exhibited an improvement in ductility as compared to the as-received sheet-rolled *** was discussed in terms of activation of non-basal slip systems and suppression of mechanical *** study successfully proved the possibility of caliber rolling to produce a bulk Mg rod with enhanced tensile properties.

关键词： Magnesium AZ31 alloy Caliber rolling Grain refinement Texture randomization Mechanical improvement

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TGF-β2 downregulates osteogenesis under inflammatory conditions in dental follicle stem cells

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International Journal of Oral Science 2018年第4期10卷 232-243页

作者： Soyoun Um Joo-hee lee Byoung-Moo Seo Biotooth Engineering Lab Dental Research InstituteDental Regenerative BiotechnologyDepartment of Dental ScienceSchool of DentistrySeoul National University Biotooth Engineering Lab Department of Oral and Maxillofacial Surgery and Craniomaxillofacial Life ScienceDental Research InstituteSchool of DentistrySeoul ational University

Bone formation is important for the reconstruction of bone-related structures in areas that have been damaged by *** conditions such as those that occur in patients with rheumatoid arthritis, cystic fibrosis, and periodontitis have been shown to inhibit osteoblastic differentiation. This study focussed on dental follicle stem cells(DFSCs), which are found in developing tooth germ and participate in the reconstruction of alveolar bone and periodontal tissue in periodontal disease. After bacterial infection of inflamed dental tissue, the destruction of bone was observed. Currently, little is known about the relationship between the inflammatory environment and bone formation. Osteogenic differentiation of inflamed DFSCs resulted in decreased alkaline phosphatase(ALP) activity and alizarin red S staining compared to normal DFSCs. Additionally, in vivo transplantation of inflamed and normal DFSCs demonstrated severe impairment of osteogenesis by inflamed DFSCs. Protein profile analysis via liquid chromatography coupled with tandem mass spectrometry was performed to analyse the differences in protein expression in inflamed and normal tissue. Comparison of inflamed and normal DFSCs showed significant changes in the level of expression of transforming growth factor(TGF)-β2. Porphyromonas gingivalis(P.g.)-derived lipopolysaccharide(LPS) was used to create in vitro inflammatory conditions similar to periodontitis. The osteogenic differentiation of LPS-treated DFSCs was suppressed, and the cells displayed low levels of TGF-β1 and high levels of TGF-β2. DFSCs treated with TGF-β2 inhibitors showed significant increases in alizarin red S staining and ALP activity. TGF-β1 expression was also increased after inhibition of TGF-β2. By examining inflamed DFSCs and LPS-triggered DFSCs, these studies showed both clinically and experimentally that the increase in TGF-β2 levels that occurs under inflammatory conditions inhibits bone formation.

关键词： TGF downregulates osteogenesis under inflammatory conditions in dental follicle stem cells

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