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应用于涡流无损检测的柔性磁阻传感器

传感器与微系统 2024年第9期43卷 165-168页

作者：赵寅瀚王海林涛孔祥燕宁波大学信息科学与工程学院浙江宁波315211 宁波大学未来无线研究院浙江宁波315211

为了研究平面探头和曲面探头在检测平面缺陷和曲面缺陷方面的差异,本文分别使用刚性印刷电路板和柔性印刷电路板(FPC)设计了刚性探头和柔性探头。实验结果表明,在平面铝板上,刚性探头和柔性探头的信噪比分别为30.2 dB和24.6 dB。在弯曲... 详细信息

为了研究平面探头和曲面探头在检测平面缺陷和曲面缺陷方面的差异,本文分别使用刚性印刷电路板和柔性印刷电路板(FPC)设计了刚性探头和柔性探头。实验结果表明,在平面铝板上,刚性探头和柔性探头的信噪比分别为30.2 dB和24.6 dB。在弯曲缺陷中,刚性探头的信噪比最低为14.8 dB,柔性探头的信噪比最低为27.1 dB。综合考虑温度稳定性、信噪比、价格等因素,刚性探头适用于小曲率的平面缺陷检测,柔性探头适用于曲面检测。

关键词：柔性探头隧道磁阻传感器涡流无损检测

Fixed-parameter tractability of capacitated k-facility location

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Frontiers of Computer Science 2023年第6期17卷 171-173页

作者： xiangyan kong Zhen ZHANG School of Computer Science and Engineering Central South UniversityChangsha 410000China School of Frontier Crossover Studies Hunan University of Technology and BusinessChangsha 410205China Changsha Social Laboratory of Artificial Intelligence Changsha 410205China

1 Introduction In this paper we study the capacitated k-facility location(Capk-FL)*** instance I of the problem is specified by a set C of clients and a set F of facilities located in a metric space with distance function d,and a positive integer k,where ICI+[F|=n,each facility f eF is associated with a capacityμ(f)>0 and a facility-opening cost o(f)>0,and connecting a client c ∈ C to f incurs a client-connection cost that equals the distance from c to f.

关键词： client problem Fixed

Transient pressure analysis in porous and fractured fractal reservoirs

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Science China(Technological Sciences) 2009年第9期52卷 2700-2708页

作者： kong xiangyan LI DaoLun LU DeTang Department of Mechanics&Mechanical Engineering University of Science and Technology of ChinaHefei 230027China

Fluid flow in porous and fractured fractal reservoirs is studied in the paper. The basic formulae of seepage velocity,permeability and porosity in both porous and fractured fractal media are developed. The pressure diffusion equation of slightly compressible fluid in fractal reservoirs is derived. The analytical solutions of the transient pressure are given for the line-source well and the well with well-bore storage and skin factor. The typical curves of pressure and the derivative of pressure are established,along with the interpretation of the well-testing method via type-curve matching. In addition,3-D pressure diffusion equations for anisotropic fractal media are given in both Cartesian coordinates and Cy-lindrical coordinates.

关键词： fluid flow porous media fractal media permeability porosity type-curves for fractal reservoirs anisotropic media

基于中性粒细胞胞外诱捕网探讨白及修复溃疡性结肠炎大鼠肠黏膜屏障的作用及机制

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中药新药与临床药理 2024年第4期35卷 453-460页

作者：陈霞樊官伟蒲翔陈云志孔祥艳陈帅柴艺汇王飞贵州中医药大学贵州贵阳550025 天津中医药大学天津300193 贵州中医药大学第一附属医院贵州贵阳550001

目的基于中性粒细胞胞外诱捕网(NETs)探讨白及对溃疡性结肠炎(UC)大鼠肠黏膜屏障的修复作用及机制。方法将48只SD大鼠随机分为正常组、模型组、柳氮磺胺吡啶组(0.3 g·kg^(-1))及白及低、中、高剂量组(0.3、0.6、1.2 g·kg^(-1)),每组8... 详细信息

目的基于中性粒细胞胞外诱捕网(NETs)探讨白及对溃疡性结肠炎(UC)大鼠肠黏膜屏障的修复作用及机制。方法将48只SD大鼠随机分为正常组、模型组、柳氮磺胺吡啶组(0.3 g·kg^(-1))及白及低、中、高剂量组(0.3、0.6、1.2 g·kg^(-1)),每组8只。采用2,4,6-三硝基苯磺酸(TNBS)-乙醇灌肠法复制UC大鼠模型,造模成功后按照设定剂量灌胃给药,每日1次,连续灌胃给药21 d。在给药干预的第1、11、21天进行疾病活动指数(DAI)评分;采用HE染色法观察大鼠结肠组织病理变化;ELISA法检测大鼠血清中肿瘤坏死因子α(TNF-α)和白细胞介素1β(IL-1β)含量;Western Blot法及免疫组化法检测大鼠结肠组织中NETs相关蛋白髓过氧化物酶(MPO)、中性粒细胞弹性蛋白酶(NE)、血管内皮生长因子(VEGF)以及紧密连接(TJs)相关蛋白封闭蛋白2(CLDN2)、闭锁小带蛋白1(ZO-1)的表达水平。结果与正常组比较,模型组大鼠DAI明显升高(P<0.05);结肠组织黏膜层出现大面积变性坏死且肠腺结构消失,大量炎性细胞浸润,累及黏膜下层、肌层和浆膜层,病理评分明显升高(P<0.05);血清TNF-α、IL-1β水平明显升高(P<0.05);结肠组织中MPO、NE、VEGF、CLDN2蛋白表达明显升高(P<0.05),ZO-1蛋白表达明显降低(P<0.05)。与模型组比较,各给药组大鼠的DAI均明显降低(P<0.05);柳氮磺胺吡啶组和白及中、高剂量组大鼠结肠肠腺结构完整清晰,黏膜未见明显变性及坏死,可见少量炎性细胞浸润,病理评分明显降低(P<0.05);血清TNF-α、IL-1β水平明显降低(P<0.05);结肠组织中MPO、NE、VEGF、CLDN2蛋白表达明显降低(P<0.05),ZO-1表达明显升高(P<0.05)。结论白及可能通过调控NETs激活及TJs相关蛋白表达,降低血清炎症因子水平,从而修复肠道黏膜屏障,发挥治疗UC的作用。

关键词：白及溃疡性结肠炎中性粒细胞胞外诱捕网肠黏膜屏障紧密连接炎症因子大鼠

Double Difference Location of the Mainshock and Aftershocks of the Hutubi MS6.2 Earthquake That Occurred on December 8,2016

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Earthquake Research in China 2018年第2期32卷 227-232页

作者： kong xiangyan Chen Xiangjun Institute of Geophysics China Earthquake AdministrationBeijing 100081China Earthquake Agency of Xinjiang Uygur Autonomous Region Urumqi 830011China

The mainshock and aftershocks of the Hutubi M_S6.2 earthquake on December 8,2016 were relocated by applying the double difference method, and we relocated 477 earthquakes in the Hutubi region. The earthquake relocation results show that the aftershocks are distributed in the east-west direction towards the north side of the southern margin of the Junggar Basin fault,and are mainly distributed in the western region of the mainshock. The distance between the mainshock after relocation and the southern margin of the Junggar Basin fault is obviously shortened. Combined with the focal mechanism and the spatial distribution of the mainshock and aftershocks,it is inferred that the southern margin of the Junggar Basin fault is the main seismogenic structure of the Hutubi earthquake.

关键词： Hutubi earthquake with MS6.2 Aftershock sequence Double difference location method Southern margin of the Junggar Basin fault

Optimization of pick-up coils for weakly damped SQUID gradiometers

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Chinese Physics B 2018年第5期27卷 137-142页

作者： Kang Yang Jialei Wang xiangyan kong Ruihu Yang Hua Chen State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information Technology (SIMIT) Chinese Academy of Sciences (CAS) Shanghai 200050 China CAS Center for Excellence in Superconducting Electronics (CENSE) Shanghai 200050 China University of Chinese Academy of Sciences Beijing 100049 China

The performance of a superconducting quantum interference device（SQUID） gradiometer is always determined by its pick-up coil geometry, such as baseline and radius. In this paper, based on the expressions for the coupled flux threading a magnetometer obtained by Wikswo, we studied how the gradiometer performance parameters, including the current dipole sensitivity, spatial resolution and signal-to-noise ratio（SNR）, are affected by its pick-up coil via Mat Lab *** on the simulation results, the optimal pick-up coil design region for a certain gradiometer can be *** verify the simulation results, we designed and fabricated several first-order gradiometers based on the weakly damped SQUID with different pick-up coils by applying superconducting connection. The experimental measurements were conducted on a simple current dipole in a magnetically shielding room. The measurement results are well in coincidence with the simulation ones, indicating that the simulation model is useful in specific pick-up coil design.

关键词： superconducting quantum interference device (SQUID) gradiometer spatial resolution dipole sensitivity signal-to-noise ratio

Study on the Crustal Structure beneath Seismic Station Bachu and Taxkorgan in Xinjiang

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Earthquake Research in China 2015年第2期29卷 265-274页

作者： Tang Mingshuai Wang Haitao Luo Ju kong xiangyan Yang Feng Earthquake Administration of Xinjiang Uygur Autonomous Region

Using the teleseismic waveform data recorded by the seismic station Bachu （hereafter referred to as station BCH ） in the Tarim Basin and the seismic station Taxkorgan （hereafter referred to as station TAG ） in the west Kunlun Mountains for years, we applied the receiver function H - K stacking method to study the crustal structure beneath stations BCH and TAG. The results showed that there are obvious differences in the crustal thickness beneath stations BCH and TAG, and the regional crustal thickness and terrain have a very good corresponding relationship. There are high crustal average Vp/Vs values beneath the two stations. The crustal thickness is 44km, and the crustal average wave velocity ratio is 1. 849 beneath station BCH. There is a sharp discontinuity in the middle of the crust beneath station BCH at a depth of 21km. There is a low average P wave velocity and low Vp/Vs from the surface to the discontinuity beneath station BCH. The depth of the discontinuity is consistent with the lower interface of the focal depth from accurate location in the Jiashi earthquake source area adjacent to station BCH; and may be the crustal brittle-ductile conversion boundary. The crustal thickness is 69km, and the crustal average wave velocity ratio is 1. 847 beneath station TAG, a thicker crust and high Vp/Vs may indicate that materials in the lower crustal are prone to plastic flow, which is responsible for the thickening of the crust.

关键词： Crustal thickness Poisson ratio Receiver function Brittle-ductile transitionzone Xinjiang

A novel superconducting quantum interference device for biomagnetic measurements

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Chinese Science Bulletin 2013年第24期58卷 2917-2919页

作者： ZHANG ShuLin ZHANG GuoFeng WANG YongLiang ZENG Jia QIU Yang LIU Ming kong xiangyan XIE XiaoMing State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information Technology Chinese Academy of Sciences Joint Research Laboratory on Superconductivity and Bioelectronics Collaboration between CAS-Shanghai and FZJ Graduate University of the Chinese Academy of Sciences

Superconducting Quantum Interference Device (SQUID) can provide an ultrahigh magnetic sensitivity for the biomagnetic measurements. In this paper, a SQUID bootstrap circuit (SBC) gradiometer was designed and fabricated. Using the SBC gradiometer, magnetocardiography (MCG), fetal MCG and magnetoencephalography (MEG) signals were detected in a magnetically shielded room.

关键词：超导量子干涉仪生物磁场磁测量 SQUID 超高灵敏度自举电路梯度仪 SBC

卵巢早衰大鼠模型建立及中医月经不调气血亏虚型模型初探

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贵州中医药大学学报 2024年第5期46卷 28-33页

作者：杨庆凤孔祥艳陈梦璐李来来柴艺汇唐英吴娜娜蒲翔贵州电力医院贵州贵阳550002 贵州中医药大学贵州贵阳550025

目的建立有效、稳定的卵巢早衰大鼠模型,为后续研究提供实验载体,并进一步探析其中医理论依据。方法将雌性SD大鼠随机分为4组,分别为空白对照组、顺铂高剂量组(4 mg/kg,腹腔注射)、顺铂中剂量组(3 mg/kg,腹腔注射)及顺铂低剂量组(2.5 mg... 详细信息

目的建立有效、稳定的卵巢早衰大鼠模型,为后续研究提供实验载体,并进一步探析其中医理论依据。方法将雌性SD大鼠随机分为4组,分别为空白对照组、顺铂高剂量组(4 mg/kg,腹腔注射)、顺铂中剂量组(3 mg/kg,腹腔注射)及顺铂低剂量组(2.5 mg/kg,腹腔注射),空白对照组予以同等体积的生理盐水进行腹腔注射,连续注射7 d后,正常喂养21 d,检测大鼠阴道上皮细胞形态与数量,血清雌二醇、促卵泡生成素水平及大鼠卵巢病理学改变。结果与顺铂高、低剂量组相比,顺铂中剂量组连续腹腔注射7 d后,大鼠毛发杂乱无光泽、唇爪苍白、倦怠懒动,动情周期明显改变,血清雌二醇明显降低,促卵泡生成素明显升高,卵巢中成熟卵泡明显减少,闭锁卵泡增多,且存活率为100%。结论中剂量(3 mg/kg)顺铂连续腹腔注射7 d为卵巢早衰大鼠模型较为理想的造模方法,具有更方便、更省时、更稳定等优势;同时,本实验模型与中医气血亏虚证型高度一致,因此建议将顺铂3 mg/kg连续腹腔注射7 d作为中医证候气血亏虚型POF的基本造模方式。

关键词：卵巢早衰气血亏虚型顺铂动物模型