检索结果-南通市图书馆

Computational Molecular Bioscience 2019年第3期9卷 63-80页

作者： Doh Soro Lynda Ekou Bafétigué Ouattara Mamadou Guy-Richard kone Tchirioua Ekou Nahossé Ziao Laboratoire de Thermodynamique et de Physico-Chimie du Milieu UFR SFA Université Nangui Abrogoua Abidjan C&#244 te-d’Ivoire Laboratoire de Physique Fondamentale et Appliquée Université Nangui Abrogoua C&#244 te d’Ivoire

In this work, we conducted a QSAR study on 18 molecules using descriptors from the Density Functional Theory (DFT) in order to predict the inhibitory activity of hydroxamic acids on histone deacetylase 7. This study is performed using the principal component analysis (PCA) method, the Ascendant Hierarchical Classification (AHC), the linear multiple regression method (LMR) and the nonlinear multiple regression (NLMR). DFT calculations were performed to obtain information on the structure and information on the properties on a series of hydroxamic acids compounds studied. Multivariate statistical analysis yielded two quantitative models (model MLR and model MNLR) with the quantum descriptors: electronic affinity (AE), vibration frequency of the OH bond (ν(OH)) and that of the NH bond (ν(NH)). The LMR model gives statistically significant results and shows a good predictability R2 = 0.9659, S = 0.488, F = 85 and p-value . Electronic affinity is the priority descriptor in predicting the activity of HDAC7 inhibitors in this study. The results obtained suggest that the descriptors derived from the DFT could be useful to predict the activity of histone deacetylase 7 inhibitors. These models were evaluated according to the criteria of Tropsha et al.

关键词： Hydroxamic Acids Histones Deacetylases DFT Histones Deacetylases Inhibitors QSAR

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

水冷的秘密（三）——水冷系统实战观摩

微型计算机 2010年第24期30卷 129-133页

作者：芒果 kone（图）

之前的水冷知识介绍都还只是纸上谈兵的阶段，在真正安装的过程中，即使规划和风险预测都做得很认真，还是可能遇到很多意料之外的麻烦。在实战篇中，就让我们来看一下“水冷帝”kone是怎么规划和安装一套水冷系统的吧。

关键词：水冷系统风险预测安装规划

Emergency Obstetric Care in Parakou: Availability in Maternity Hospitals, Knowledge, Attitudes and Practices of Providers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Obstetrics and Gynecology 2018年第8期8卷 707-719页

作者： Kabibou salifou Achille Awede A. Obossou Idriss Olojuwole Alassane Imorou Rachidi Sidi Mahublo Vodouhe Fanny Hounkponou Didier Komongui Rene-Xavier Perrin UFR of Gynecology and Obstetrics Faculty of Medicine University of Parakou Parakou Benin UFR of Gynecology and Obstetrics Faculty of Health Sciences University of Abomey-Calavi Cotonou Benin

Objective: To evaluate the availability of emergency obstetric care (EmOC) in maternity hospitals in Parakou as well as the knowledge, attitudes and practices of EmOC providers in 2017. Material and method: This was a descriptive, cross-sectional analytical study conducted in the maternity wards of public and private health facilities in Parakou and the health care providers of the maternity wards. Epi Data software version 3.1, Epi Info version 7.2 and EXCEL 2007 were used for data processing. Results: A total of 17 maternity homes and 91 providers participated in the study. All 7 basic functions (BEmOC) were available in 23.53% of these maternities. Providers’ knowledge of EmOC was good at 6.59%, average at 15.38%, insufficient at 24.18% and bad at 53.85%. As for the attitudes, they were just in 3.30%, approximate in 36.26%, wrong in 26.37% and harmful in 34.07%. Regarding the practices of these providers, they were adequate in 6.59%, inadequate in 38.46% and harmful in 54.95%. The global knowledge, attitudes and practices (CAP) score is acceptable in the majority of providers (57.14%). It is poor in 38.46% and good in 4.40%. Conclusion: In Parakou, the availability of emergency obstetric care (EmOC) contrasts with the level of knowledge, attitudes and practices of providers who require training in EmOC.

关键词： Emergency Obstetric Care Availability Knowledge Attitude Practice

Reconstruction of Post-Traumatic Bone Loss (BL) Members: Our Experience about 27 Cases

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Orthopedics 2016年第6期6卷 139-143页

作者： Moctar Traore Samba kone Maurice Kouame Raphael Dallo Gogoua Armand Yepie Michel Anoumou Guy Varango Department of Orthopaedic Surgery and Traumatology C.H.U de Treichville Abidjan Cote d’Ivoire Department of Orthopaedic Surgery and Traumatology C.H.U de Cocody Abidjan Cote d’Ivoire

The purpose of this study is to evaluate our results of treatment of post-traumatic bone defect of members through various bone reconstruction techniques. Patients and method: It is a retrospective study continues from January 2008 to December 2012. It involved 27 patients who had bone loss following trauma members. The average age of patients was 36.2 years. We noted a male predominance (22 men). The causes of injuries were dominated by accidents of public roads (12 cases) and ballistic trauma (14 cases). We noted one case of work accident. The BL was localized in 10 cases the tibia, femur in 4 cases, 8 cases in the humerus, 2 cases in the fibula, 1 case was located in the olecranon, 1 case at the distal radius and 1 case to the ball. All lesions were open fractures. After a mean of support for 3 days, we performed emergency around 19 associated with internal fixation (10 cases external fixation, internal fixation 9 cases), 8 single around. Bone reconstruction was performed secondarily in the majority of cases (24 cases). Only 4 reconstructions were performed in emergency. Reconstruction techniques were dominated by conventional grafts (24 cases) associated or not with the technique of induced membrane. Bone reconstruction techniques we used were as follows: 24 cases of traditional autografts and 3 cases of intertibio-fibular graft. After an average decline of 43.6 months, our patients were evaluated clinically (axis and limb length) and radiological (bone healing). Results: bone healing was achieved in 22 cases after a mean of 3.8 surgeries and an average of 14.8 months. Conclusion: the main principles governing the reconstruction of a defect are pre healing associated infection and repair soft tissue whenever it can do. The current trend is to hybridization of the reconstruction process of the great losses of substance by developing strategies based on both the deliberate shortening.

关键词： Bone Loss Bone Reconstruction Nonunion

Some Processing Steps and Uses of Cashew Apples: A Review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food and Nutrition Sciences 2023年第1期14卷 38-57页

作者： Lou Boli Caroline Sahie Doudjo Soro Kisselmina Youssouf kone Nogbou Emmanuel Assidjo Kouassi Benjamin Yao Ecole Doctorale Polytechnique (EDP) of Institut National Polytechnique Félix Houphouë t-Boigny (INP-HB) Yamoussoukro C&#244 te d’Ivoire

In addition to the cashew nut, which is the main product, the cashew tree also produces the cashew apple which is considered a by-product. The cashew apple has a high nutritional potential. Indeed, it is rich in vitamin C, carotenoids, dietary fibers, vitamins, sugars and mineral elements where are essential for human nutrition. In addition to its nutritional quality, the cashew apple has technological advantages: the edible part of the fruit is between 85% and 100% higher than that of other traditional tropical fruits, and its juicy and sweet flesh is free of seeds or pits. In addition, very large volumes are available. As a result, the development of this fruit represents a considerable economic challenge. This paper first presents the cultivation of cashew trees and the bibliography of the work done on cashew juice. The favorable conditions for cashew tree cultivation and the planting method were presented. Then, the study highlights the work done on the physicochemical characteristics of cashew apples, the effect of the growing area, the variety and the stage of maturity on its characteristics. It also shows the influence of the processing steps on the nutritional value and organoleptic quality of the cashew apple;as well as the methods of clarification, stabilization, concentration and dehydration. Some uses of cashew apple were reviewed: beverage, food, substrate, bioethanol, nutraceutical, food additive and agro materials.

关键词： Cashew Apple Processing Use

Epidemiological and Clinical Aspects of Bladder Tumours at the Nianankoro Fomba Hospital in Segou in the Urology Department

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Urology 2022年第5期12卷 294-303页

作者： Sory Ibrahim kone Honoré Jean Gabriel Berthe Aly Douro Tembely Zanafon Ouattara Mamadou Lamine Diakite Urology Department Nianankoro Fomba Hospital Ségou Mali Department of Urology CHU Point G Bamako Mali Department of Urology CHU Gabriel TOURE Bamako Mali Department of Urology CHU Gabriel TOURE Bamako Mali

Objectives: To study the epidemiological, diagnostic and prognostic aspects of bladder tumours in Segou Hospital. Patients and Methods: We conducted a descriptive cross-sectional study of bladder tumours over the period from 1 April 2012 to 1 April 2017, in the urology department of the Nianankoro Fomba Hospital in Segou. The first three years were used for patient recruitment, and the last two years for follow-up of the patients in the series. Results: Over a period of three years, we collected 165 cases of bladder tumours hospitalised out of 1308 hospitalisations from 7007 consultations, i.e. 12.6% of hospitalisations and 2.3% of consultations. The sex ratio was 1.2 in favour of men. A history of treated bilharzia was reported in 78.8% of cases and untreated bilharzia in 9.1% of cases. Haematuria was the most common reason for consultation. The majority of our patients were at stage T4 and T3 at the time of diagnosis, i.e. 53.3% and 44.3% respectively. Most patients consulted within 13 to 24 months after the first sign, i.e. 44.8%. Conclusion: The prognosis is still clouded by the delay in management. All the patients diagnosed had a bladder tumour infiltrating the muscle.

关键词： Bladder Tumour Bladder Cancer Epidemiological and Clinical Aspects

Mapping of Pollution Risk of Surface Waters by Runoff from Watershed: Case of Aghien Lagoon (South of Côte d’Ivoire)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Water Resource and Protection 2015年第17期7卷 1457-1466页

作者： Konan Jean-Pierre Koffi Yao Alexis N’Go Diakaria kone Kouakou Hervé Kouassi Savané Issiaka Laboratory of Geosciences and Environment of University of Nangui Abrogoua Abidjan C&#244 te d’Ivoire Department of Water Resources National Office of Drinking Water (ONEP) Abidjan C&#244 te d'Ivoire

The operating capacity of the Abidjan’s groundwater became insufficient. The deficit in drinking water resources in the District of Abidjan remains the major concern of the decision maker. The Aghien lagoon stands as one of the most interesting alternatives. However, studies show the levels of pollutions of this resource without lighting out on the causes and sources of these pollutions. The present study extends over the entire catchment of the Aghien lagoon which reveals the presence of urban areas and agricultural activity areas. This raises real concerns for the Ivorian authorities. This study suggests making cartography of the risk levels of pollution on the Aghien lagoon by the surface runoff on the watershed to enlighten the decision-makers on the possible measures to be taken for the protection of this resource. It emerges from it that the risk of contamination of the lagoon is very likely. Agricultural and domestic best practices inside the pouring pond are compulsory to fight against the pollutions of this resource.

关键词： Pollution Risk Watershed GIS Aghien Lagoon Abidjan

Improving Churn Prediction in Telecommunications using Complementary Fusion of Multilayer Features based on Factorization and Construction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Improving Churn Prediction in Telecommunications using Compl...

Double Volvulus, Transverse Colon and Sigmoid at Kati Chu BSS: About 2 Cases

第26届中国控制与决策会议

作者： Qiuhua Shen Hong Li Qin Liao Wei Zhang kone KALILOU School of Information Science and Engineering Central South University School Of Architecture Hunan University

ISBN: (纸本)9781479937097

High dimensional and unbalanced datasets are the main problems which prevent from achieving ideally churn prediction performance. Features selection is necessary to be adopted to enhance the model performance. A new predicting framework is proposed in this paper which uses complementary fusion of the multilayer features. Several subsets and new features were acquired according to feature factorization and feature construction respectively. The effective features were selected by multilayer complementary fusion which according to the contribution of feature subsets and new features. In this way, the imbalance defects of class distributions can be fixed, prediction accuracy can be improved and system stability can be reinforced. Five data mining models were applied in customer churn. Experimental results demonstrated that the method we proposed could preferably overcome the inelasticity of traditional feature selection algorithms, and more effective than those existing methods in telecommunications industry. Furthermore, we found optimal fusion with prediction model for customer churn prediction in telecommunications industry through exploring the advantages and limitations of each feature subset and prediction techniques.

关键词： Customer Churn Prediction Prediction techniques Feature Selection Complementary Fusion Feature Factorization Feature Construction

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Surgical Science 2021年第8期12卷 296-301页

作者： Koniba Keita Abdoulaye Diarra Sidiki Keita Fodé Mory Keita Oulematou Coulibaly Amadou Traoré Assitan kone Salia Coulibaly Aimé Christophe Dembélé Oumou Koné Birama Togola Daouda Diallo Boubacar kone Drissa Traoré Bacary T. Dembélé General Surgery Department Hospital BSS Kati Mali General Surgery “A” Department Hospital Point-G Bamako Mali Reference Heath Centre of the Commune VI Bamako Mali General Surgery Department Hospital Gabriel Touré Bamako Mali Medical Imaging Department Hospital BSS Kati Mali General Surgery “B” Department Hospital Point-G Bamako Mali Anesthesia Resuscitation Department Hospital BSS Kati Mali

The simultaneous double volvulus of the transverse colon and sigmoid in the same patient is a rare cause of intestinal occlusion. Two cases were observed in general surgery in Kati. Its clinical symptomatology does not differ from other occlusions as well as simple radiological images. It is an extreme surgical emergency, the diagnosis is generally intraoperative. Extensive left hemi colectomy with terminoterminal rectal anastomosis was performed. The surgical follow-up was simple.

关键词： Volvulus Transverse Sigmoïde Surgery Colon

In Vitro Evaluation of the Antifungal Activity of Essential Oils of Thymus vulgaris and Cymbopogon citratus on Some Strains of Sclerotinia sclerotiorum, Agent Responsible for White Rot of Beans

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Agricultural Sciences 2023年第8期14卷 1068-1086页

作者： Serge Bertrand Mboussi Alain Heu Abdou Nourou kone Nsangou Jules Patrice Ngoh Dooh Zachée Ambang Laboratory of Biotechnology University Institute of Technology University of Douala Douala Cameroon Department of Agriculture and Agropastoral Higher Technical Teachers Training College Ebolowa Cameroon Applyied Botanic Research Unit Department of Plant Biology University of Dschang Dschang Cameroon Department of Biological Sciences Faculty of Sciences University of Maroua Maroua Cameroon Biotechnology Laboratory Phytopathology and Microbiology Unit University of Yaoundé I Yaoundé Cameroon

The present work was aimed to the study of the antifungal activity of essential oils of two aromatic plants against three strains of Sclerotinia sclerotiorum responsible for white rot of bean. The two essential oils (EO) of the studied plants: Thymus vulgaris (HET) and Cymbopogon citratrus (HEC), used at different concentrations: C1 (0.75 ml/ml), C2 (1.5 ml/ml) and C3 (3 ml/ml) presented significant inhibitory activities on the three tested fungal strains namely Bia 1, Bia 2, and Njo 2. Two control treatments (T-: containing no antifungal substance and T+: synthetic fungicide) were also used. The antifungal activity here is related to the inhibition of mycelial growth especially with high concentrations of essential oils. Thus, against S. sclerotiorum, HET showed the highest activity comparable to that of T+ (100% inhibition) at all concentrations on the Bia 1 and Bia 2 strains and at concentration C3 on the Njo 2 strain compared to that of HEC, which certainly inhibited the mycelial growth of the different strains considerably (with a maximum of 78.15% on the Njo 2 strain) but not completely. According to their sensitivity, the Bia 2 strain showed a higher sensitivity to essential oils than the others while the Njo 2 strain was more aggressive. On the basis of MIC50 and MIC90 obtained on the Njo 2 strain, the HET turns out to be the most efficient with respective lower values of (1.73 and 23.34 ml/ml) against (4.76 and 26.03 ml/ml) for the HEC. These EO could thus be exploited as biodegradable antifungal substances, likely to control white rot of bean.

关键词： S. sclerotiorum T. vulgaris C. Citratrus Essential Oils Antifungal Activity Inhibition