检索结果-南通市图书馆

Prevalence and risk distribution of schistosomiasis among adults in madagascar:a cross-sectional study

Infectious Diseases of Poverty 2023年第2期12卷 136-136页

作者： Sarah Katharina Gruninger Tahinamandranto Rasamoelina Rivo Andry Rakotoarivelo Anjarasoa Ravo Razafindrakoto Zaraniaina Tahiry Rasolojaona Rodson morin Rakotozafy Patrick Richard Soloniaina Njary Rakotozandrindrainy Pia Rausche Cheick Oumar Doumbia Anna Jaeger Alexandre Zerbo Heidrun von Thien Philipp Klein Govert van Dam Egbert Tannich Norbert Georg Schwarz eva lorenz Jürgen may Raphael Rakotozandrindrainy Daniela Fusco Department of Infectious Disease Epidemiology Bernhard Nocht Institute for Tropical Medicine Hamburg Germany German Centre for Infection Research (DZIF) Hamburg-Borstel-Lübeck-Riems Germany Centre d’Infectiologie Charles mérieux (CICm) University of Antananarivo Antananarivo Madagascar Department of Infectious Diseases University of Fianarantsoa Andrainjato Fianarantsoa Madagascar Department of microbiology and Parasitology University of Antananarivo Antananarivo Madagascar University Clinical Research Centre (UCRC) University of Sciences Technics and Technologies of Bamako (USTTB) Bamako Mali Department of Parasitology Leiden University Medical Centre Leiden The Netherlands National Reference Centre for Tropical Pathogens (NRC) Hamburg Germany Institute of medical Biostatistics Epidemiology and Informatics University Medical Centre of the Johannes Gutenberg University Mainz Mainz Germany Department of Tropical.m.dicine I University Medical Center Hamburg-Eppendorf (UKE) Hamburg Germany

Background The goal to el.m.nate the parasitic disease of poverty schistosomiasis as a public health probl.m.is aligned with the 2030 United Nations agenda for sustainable development goals,including universal health coverage(UHC).Current control strategies focus on school-aged children,systematically neglecting *** aimed at providing evidence for the need of shifting the paradigm of schistosomiasis control programs from targeted to generalized approaches as key el.m.nt for both the el.m.nation of schistosomiasis as a public health probl.m.and the promotion of *** In a cross-sectional study performed between march 2020 and January 2021 at three primary health care centers in Andina,Tsiroanomandidy and Ankazomborona in madagascar,we determined prevalence and risk factors for schistosomiasis by a semi-quantitative PCR assay from specimens collected from 1482 adult *** and multivariable logistic regression were performed to evaluate odd *** The highest prevalence of ***,*** and co-infection of both species was 59.5%,61.3%and 3.3%,in Andina and Ankazomborona *** prevalence was observed among males(52.4%)and main contributors to the family income(68.1%).Not working as a farmer and higher age were found to be protective factors for *** Our findings provide evidence that adults are a high-risk group for *** data suggests that,for ensuring basic health as a human right,current public health strategies for schistosomiasis prevention and control need to be re-addressed towards more context specific,holistic and integrated approaches.

关键词： Schistosomiasis Schistosoma haematobium Schistosoma mansoni Universal health coverage madagascar

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genetic causes of macrozoospermia and proposal for an optimized genetic diagnosis strategy based on sperm parameters

引用

Journal of Genetics and Genomics 2023年第7期50卷 536-540页

作者： Alicia Coudert Caroline Cazin Amir Amiri-Yekta Sel.m. Fourati Ben mustapha Raoudha Zouari Julien Bessonat Abdelali Zoghmar Antoine Clergeau Catherine metzler-Guill.m.in Chema Triki Herve lejeune Nathalie Sermondade eva Pipiras Nadia Prisant Isabelle Cedrin leila Keskes Florence lestrade laetitia Hesters Nathalie Rives Beatrice Dorphin Agnes Guichet Catherine Patrat Emmanuel Dulioust Aur elie Feraille Franc ois Robert Eric Bieth Arthur Sorlin Jean-Pierre Siffroi mariem Ben Khelifa Florence Boiterelle Sylvianne Hennebicq Veronique Satre Christophe Arnoult Charles Coutton Anne-laure Barbotin Nicolas Thierry-mieg Zine-Eddine Kherraf Pierre F.Ray Genetic Epigenetic and Therapies of Infertility Team Institute for Advanced BiosciencesInserm U 1209CNRS UMR 5309Universite Grenoble Alpes38000GrenobleFrance CHU Grenoble Alpes UM GI-DPI38000GrenobleFrance CHU Grenoble Alpes UM de Genetique Chromosomique38000GrenobleFrance Department of Genetics Reproductive Biomedicine Research CenterRoyan Institute for Reproductive BiomedicineACECRTehranIran Polyclinique les Jasmins Centre d’Aide M edicale a la Procr eationCentre Urbain Nord1003TunisTunisia CHU Grenobles Alpes UF de Biologie de la Procr eation38000GrenobleFrance Reproduction Sciences and Surgery Clinique Ibn RochdConstantineAlgeria CHU Caen CECOS de CaenD epartement de BiologieUnit e de Biologie de la Reproduction14033CaenFrance APHm Hopital la-Conception P^ole Femmes-parents-enfantsCentre Clinico-biologique d’assistance M edicale a la Procr eation-CECOS13385 MarseilleFrance Aix-marseille Univ InsermMMGU125113385 Marseille Medical Genetics13385 MarseilleFrance Clinique Hannibal Centre d’AMPLes Berges du Lac1053TunisTunisia Reproductive medicine Department Hospices Civil de LyonLyonFrance Hopital Jean Verdier Universit e Sorbonne Paris NordParisFrance CHU de Pointe-a-Pitre/Abymes GuadeloupeFrance Service de medecine de la Reproduction CHU Jean VerdierParisFrance Faculte de m edecine de Sfax SfaxTunisia CHR metz-Thionville Service d’Assistance Medicale a la Procr eation57530Ars-LaquenexyFrance Unit of Reproductive Biology Antoine B ecl ere University HospitalUniversity Paris SudClamartParis-Sud UniversityLe Kremlin Bic^etreFrance Univ Rouen Normandie Inserm U1239NorDICAdrenal and Gonadal PathophysiologyReproductive Biology Laboratory-CECOSRouen University Hospital76031Rouen CedexFrance CHAl Centre Hospitalier Alpes l.m.n Centre AMP7474130Contamine-sur-ArveFrance CHU Angers Service de Gen etique49933AngersINSERM U1083France Service de Biologie de la Reproduction-CECOS Hopital Cochin 74014ParisFrance IRH medicentre Clinique du Val d’Ouest39

macrozoospermia,characterized by the presence of largeheaded spermatozoa usually carrying several flagella,is one of the most severe phenotypes of male *** in most cases,the gametes are chromosomally abnormal and cannot be used for assisted reproductive technologies(ART)(Ray et al.,2017).In 2007,subjects from consanguineous families were shown to carry the same homozygous deleterious AURKC variant(Nm_001015878.2:c.144delC,later renamed c.145delC,***49TrpfsTer23),establishing AURKC as the first and main gene associated with macrozoospermia(Dieterich et al.,2007).Using flow cytometry,all spermatozoa from patients homozygous for the c.145delC variant were shown to be tetraploid,highlighting a cytokinesis blockage of the first meiotic divisions thus confirming that ART cannot be successful for these patients(Dieterich et al.,2009).

关键词： diagnosis establishing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Assessment of lung Cancer Risk on the Basis of a Biomarker Panel of Circulating Proteins

Assessment of Lung Cancer Risk on the Basis of a Biomarker P...

引用

2019年中国肿瘤标志物学术大会暨第十三届肿瘤标志物青年科学家论坛

作者： sun,nan Florence,Guida Bantis,leonidasE. muller,DavidC. li,Peng Taguchi,Ayumu Dhillon,Dilsher Kundnani,Deepalil. Patel,NikulJ. Yan,Qingxiang Byrnes,Graham moons,KarelG.m. Tj?nneland,Anne Panico,Salvatore Claudia ,Agnoli Vineis,Paolo Palli,Domenico Bueno-de-mesquita,Bas Peeters,PetraH. Agudo,Antonio Huerta,Josem. Dorronsoro,miren Barranco,miguelRodriguez Ardanaz,eva Travis,RuthC. Byrne,Karl.m.th Boeing,Heiner Steffen,Annika Kaaks,Rudolf Hüsing,Anika Trichopoulou,Antonia lagiou,Pagona laVecchia,Carlo Severi,Gianluca Boutron-Ruault,marie-Christine Sandanger,Torkjelm. Weiderpass,Elisabete N?st,ThereseH. Tsilidis,Kostas Riboli,Elio Grankvist,Kjell Johansson,mikael Goodman,GaryE. Feng,Ziding Brennan,Paul Johansson,mattias Hanash,Samir m. The University of Texas mD Anderson Cancer Center Genetic Epidemiology Group International Agency for Research on Cancer Department of Biostatistics The University of Texas MD Anderson Cancer Center Department of Epidemiology and Biostatistics Imperial College London School of Public Health laboratory of Population Health Max Planck Institute for Demographic Research Department of Translational.m.lecular Pathology The University of Texas MD Anderson Cancer Center Environment and Radiation Section International Agency for Research on Cancer Department of Epidemiology Julius Center for Health Sciences and Primary CareUniversity Medical Center Unit of Diet Genesand EnvironmentDanish Cancer Society Research Center Department of Clinical.m.dicine and Surgery Federico Ⅱ University Epidemiology and Prevention Unit Fondazione IRCCS Istituto Nazionale dei Tumori molecular and Genetic Epidemiology Unit Human Genetics Foundation Cancer Risk Factors and life-Style Epidemiology Unit Cancer Research and Prevention Institute-Istituto per lo Studio ela Prevenzione Oncologica Department for Determinants of Chronic Diseases National Institute for Public Health and the Environment Unit of Nutirition and Cancer Cancer Epidemiology Research ProgramCatalan Institute of OncologyBellvitge Institute for Biomedical Research (IDIBELL)L’Hospitalet de Llobregat Department of Epidemiology Murcia Regional Health Council Biomedical Research Institute of Murcia(IMIB-Arrixaca) Centro de Investigación Biomédica en Red Epidemiología y Salud Pública (CIBERESP) Public Health Direction and Biodonostia Research Institute-CIBERESP Escuela Andaluza de Salud Pública Instituto de Investigación Biosanitaria Hospitales Universitarios de Granada/Universidad de Granada Epidemiology Preventionand Promotion Health ServiceNavarra Public Health Institute Instituto de Investigación Sanitaria de Navarra (IdiSNA) Navarra Institute for Health Research Cancer Epidemiology Unit Nuffield Department of Population HealthUniversity of Oxford Department of Epidemi

ImPORTANCE:There is an urgent need to improve lung cancer risk assessment because current screening criteria miss a large proportion of ***:To investigate whether a lung cancer risk prediction model based on a panel of selected circulating protein biomarkers can outperform a traditional risk prediction model and current US screening criteria.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

注意力缺陷/多动症和儿童期自闭症与产前暴露于全氟烷基物质之间的关联:丹麦全国出生队列的一项巢式病例对照研究

引用

环境与职业医学 2015年第10期32卷 920-920页

作者： Zeyan liew Beate Ritz Ondine S.von Ehrenstein Bodil Hammer Bech Ellen Aagaard Nohr Chunyuan Fei Rossana Bossi Tine Brink Henriksen eva Cecilie Bonefeld-Jφrgensen Jφrn Olsen

[背景]全氟烷基物质(PFASs)是持久性污染物,动物实验中具有内分泌干扰性和神经毒性。一些横断面数据显示PFASs与儿童神经行为的问题之间存在正向关联,但是来自前瞻性研究的结果仍然有限。[目的]研究产前暴露于PFASs是否与儿童中的注意... 详细信息

[背景]全氟烷基物质(PFASs)是持久性污染物,动物实验中具有内分泌干扰性和神经毒性。一些横断面数据显示PFASs与儿童神经行为的问题之间存在正向关联,但是来自前瞻性研究的结果仍然有限。[目的]研究产前暴露于PFASs是否与儿童中的注意力缺陷/多动障碍(ADHD)或儿童期自闭症之间有关联。[方法]在1996—2002年丹麦全国出生队列的83 389对母子中,根据丹麦国家医院登记和丹麦精神病中心登记,确定了890名ADHD病例和301名儿童自闭症病例。从这个队列中,随机各选择220例多动症和自闭症病例,并随机选择550例性别相匹配的对照儿童。测量在妊娠早期或中期采集的母体血浆中16种PFASs,使用广义线性模型计算风险比(RRs),模型中考虑到了抽样权重。[结果]在所有样品中均检测到全氟辛烷磺酸(PFOS)和全氟辛酸(PFOA),在≥90%的样本中可以定量其他4种PFASs。没有发现母亲PFAS血浆水平和ADHD之间关联的一致性证据[浓度(ng/m l)的自然对数值每增加一个单位,PFOS对应的RR=0.87(95%CI:0.74,1.02),PFOA对应的RR=0.98(95%CI:0.82,1.16)],对于自闭症也是如此[浓度(ng/m l)的自然对数每增加一个单位,PFOS对应的RR=0.92(95%CI:0.69,1.22),PFOA对应的RR=0.98(95%CI:0.73,1.31)]。在同时校正所有PFASs的模型中,较高的PFAS分位数和ADHD之间既有阳性关联也有阴性关联,但是这些关联的估计值并不精确。[结论]在这项研究中,没有发现一致性的证据能够提示产前PFAS暴露增加儿童中ADHD或儿童期自闭症儿的风险。

关键词：巢式病例对照研究儿童自闭症注意力缺陷出生队列产前暴露儿童期多动症丹麦

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Endocrine and metabolic effects of metformin in combination with compound cyproterone acetate in women with polycystic ovarian syndrome

引用

生殖医学杂志 2003年第Z1期12卷 24-32页

作者：叶碧绿杨海燕赵军招林金菊林文琴 Department of Reproductive medicine The First Affiliated Hospital of Wenzhou Medical CollegeWenzhouZhejiang 325000China

Objective:To study the endocrinologic and metabolic effects of metformin in combi-nation with compound cyproterone acetate (CPA) on patients with polycystic ovariansyndrome (PCOS).methods: A prospective study involved total 65 patients, 45 PCOS patients as group Aand 20 non-PCOS infertility patients as control (group B). Complete baseline work-up inclu-ding body mass index (BmI), waist/hip ratio(WHR), Ferriman-Gallwey score(FGS), gona-dotrophin, testosterone(T), sex hormone-binding globulin (SHBG), dehydroepiandrosteronesulfate (DHEAS), and fasting lipid, glucose (FG) , insulin (FI) and oral glucose tolerancetest (OGTT), were performed in all patients. Patients in group A were treated with CPA a-lone (group A1), metformin alone (group A2) or combination of CPA with metformin (groupA3) , respectively by randomizatior. At the end of the 12-week therapy, subjects were re-evaluated and above parameters were ***: Women in group A had significant increases in BmI, WHR, FGS, lH, T,FI, insulin resistance (IR), triglycerides(TG), and significant decrease in HDl-C com-paring with the control group (P＜0.01). No significant difference among A1, A2 andA3 were found at baseline. lH, T, FT (free testosterone) were significant decreasedfrom (13.9±5.9)IU/l, (2. 1±0. 8)nmol/l and (2.8±2.3)nmol/l respectively to(5.8±2.2)IU/l, (1.2±0. 4)nmol/l and (0. 8±0.5)nmol/l respectively and SHBGwas significant increased from (99 ± 42) nmol/l to (187±64)nmol/l in group A3,when compared with lH,T and FT from (13.8±7.6)IU/l, (2.2±1.1) nmol/l and(2. 5±1.9) nmol/l respectively to (11.8±6.5)IU/l, (1.8±0.8) nmol/l and (1.7±1.0) nmol/l respectively and SHBG from (99±40) nmol/l to (120±51) nmol/l ingroup A2 (P＜0.05,P＜0. 001). HDl-C was significant increased from (1.5±0.3)mmol/l to (1.8±0.3) mmol/l in group A3 comparing with HDl-C from (1.5±0.4)mmol/l to (1.6±0.4) mmol/l in groupA1(P＜0.001).Conclusions: The PCOS patients treated with metformin in combination with compoundcyproterone acetate m

关键词： Polycystic ovary syndrome metformin Ethinyl oestradiol/cyprot-erone acetate pill Hyperinsulinism

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：