检索结果-南通市图书馆

Efficacy of Postoperative Adjuvant Chemotherapy According to Prognostic Factor in Patients with Stage III Colon Cancer

引用

Journal of Cancer Therapy 2014年第8期5卷 806-816页

作者： Kiichi Sugimoto Kazuhiro Sakamoto Yuichi Tomiki Michitoshi Goto Yutaka kojima Hiromitsu Komiyama Makoto Takahashi Shun Ishiyama Koichiro Niwa Haruna Okubo Department of Coloproctological Surgery Juntendo University Faculty of Medicine Tokyo Japan

Background: We retrospectively identified prognostic factors in patients with Stage III colon cancer and considered the effectiveness of postoperative adjuvant chemotherapy based on these prognostic factors. Methods: Two hundred and thirty four patients with lymph node metastases who underwent curative surgery for colon cancer between 1999 and 2005 were enrolled in the present study. Firstly, clinicopathological factors and survival data, were analyzed to determine prognostic factors related to cancer-specific survival. Secondly, we examined the effectiveness of postoperative adjuvant chemotherapy based upon these prognostic factors. Results: The multivariate analysis revealed that differentiation (P = 0.03, Hazard ratio = 2.50), lymphatic invasion (P = 0.02, Hazard ratio = 3.23) and the TNM classification, 7th?edition (P = 0.04, Hazard ratio = 1.94) were found to be significant independent prognostic factors. Among the patients classified as TNM IIIA, the recurrence-free survival rates were extremely good. Among the patients classified as IIIB and IIIC, there was no significant difference between the patients with and without postoperative adjuvant chemotherapy. Conclusion: The present study suggests that the patients with Stage IIIA colon cancer may not require postoperative adjuvant chemotherapy. The addition of oxaliplatin to 5-FU should be considered for the patients with Stage IIIB and IIIC colon cancer, for whom the prognoses are far from satisfactory.

关键词： Colorectal Cancer Postoperative Adjuvant Chemotherapy Prognostic Factor Stage III Colon Cancer TNM Classification 7th Edition

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Impact of Chylous Ascites on Colon Cancer in Laparoscopic Surgery

引用

Open Journal of Gastroenterology 2018年第7期8卷 269-274页

作者： Shinya Munakata Kazuhiro Sakamoto Kumpei Honjo Masaya Kawai Kiichi Sugimoto Masakazu Ouchi Makoto Takahashi Yutaka kojima Kunihiko Nagakari Yuichi Tomiki Department of Coloproctological Surgery Juntendo University Faculty of Medicine Tokyo Japan

Objectives: To investigate the epidemiology and risk factors of chylous ascites. Methods: We identified the cases of 913 consecutive patients who underwenturgery for colorectal cancerat our University Hospital between January 2005and December2016. We divided the patients into thosewith and those without chylous ascites and compared the two groups by age, gender, body mass index, tumor location, T, N factor, stage, operation time, intra-operative bleeding, and duration of postoperative hospital stay. Results: Chylous ascites developed in 8 of the 913 patients (0.8%). Neither age, sex, tumor location, and body mass indexnor number of lymph nodeswereassociated with postoperative chylous ascites. Ascites occurred significantly less frequently in the early stage of colorectal cancer than in the late stage (p = 0.04). There was no significant difference between the groups in operative factors, including operation time and blood loss. Postoperative hospital stays were longer in patients with chylous ascites (20.5 days) than in those without (11 days) (p = 0.02). Conclusions: Late stage was one of the risk factors for chylous ascites in the present study. Other risks, such as tumor location and blood loss,will vary from institution to institution.

关键词： Chylous Ascites Colon Cancer Epidemiology Laparoscopic Surgery Risk Factor

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Absorption Spectroscopy with the Coherent THz Radiation from Linac Electron Beams

Absorption Spectroscopy with the Coherent THz Radiation from...

引用

作者： S.Okuda T.kojima R.Taniguchi D.Komatsu T.Takahashi Radiation Research Center Osaka Prefecture University

INTRODUCTION:Coherent synchrotron and transition radiation from electron bunches of a linear accelerator (linac) has a continuous spectrum at relatively high peak-intensity in a YHz frequency *** radiation light sources for applications were first established in Kyoto University and Osaka University. Recently,the absorption spectroscopy system using the coherent transition radiation from the electron beams of the L-band electron linac has been established at KURRI .With this system absorption spectroscopy has been carried out for various kinds of samples in our project.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

行为问题及注意力缺损伴多动儿童脑电图跨国研究

引用

中国心理卫生杂志 1991年第4期5卷 150-154+190-191页

作者：何渝,侯沂,王玉凤,沈渔邨,Matsuura M,Okubo Y.,kojima T.,Takahash R.,Lee C.K. 北京医科大学精神卫生研究所北京医科大学精神卫生研究所北京医科大学精神卫生研究所北京医科大学精神卫生研究所东京医科齿科大学东京医科齿科大学东京医科齿科大学东京医科齿科大学汉城国立大学中国中国中国中国日本日本日本日本南朝鲜

根据 Rutter 行为问题问卷,对检出的行为问题儿童日本27名,中国39名及南朝鲜87名进行脑电图分析,并以各自国家匹配的正常儿童日本30名,中国27名,南朝鲜26名脑电图作对照比较。在各自国家中,两组间脑电图均未见显著差异;而在精神科诊断... 详细信息

根据 Rutter 行为问题问卷,对检出的行为问题儿童日本27名,中国39名及南朝鲜87名进行脑电图分析,并以各自国家匹配的正常儿童日本30名,中国27名,南朝鲜26名脑电图作对照比较。在各自国家中,两组间脑电图均未见显著差异;而在精神科诊断为注意力缺损伴多动(ADD-H)儿童日本21例,中国41例,南朝鲜29例与正常儿童、行为问题儿童脑电图相比较,各个国家中均有显著性差异。日本和中国资料表明,ADD-H 儿童脑电图峰频移向慢频率带;其它若干慢波指标在三个国家均比各自的对照组高。提示注意力缺损伴多动与生物功能异常有关。

关键词：行为问题注意力缺损伴多动儿童 EEG 跨国研究慢波中国日本南朝鲜

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Human B7-H3 binds to Triggering receptor expressed on myeloid cells-like transcript 2 (TLT-2) and enhances T cell responses

引用

Open Journal of Immunology 2012年第1期2卷 9-16页

作者： Masaaki Hashiguchi Yuka Inamochi Shoya Nagai Noriko Otsuki Jinhua Piao Hiroko Kobori Yumiko Kanno Hidefumi kojima Tetsuji Kobata Miyuki Azuma Department of Immunology Dokkyo Medical University School of Medicine Mibu Tochigi Japan Department of Molecular Immunology Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University Tokyo Japan

The B7 family member B7-H3 is broadly expressed in many tissue and tumor types. B7-H3 expression is induced on some immune cells;however, its immunological function remains controversial, because both immunoenhancing and immunoinhibitory effects have been reported in human and mouse systems. We have previously reported the following: 1) murine B7-H3 specifically bound to Triggering receptor expressed on myeloid cells (TREM)-like transcript 2 (TLT-2, TREML2), a member of the TREM family of receptors;and 2) the B7-H3:TLT-2 pathway up-regulated T cell responses. However, the expression and function of human TLT-2 has not yet been clarified. A recent study found no evidence to support the existence of an interacttion between human B7-H3 and TLT-2. In this study, we demonstrated that human B7-H3 binds to TLT-2 and augments T cell responses. Human and mouse B7-H3Ig chimeric proteins cross-interacted with both human and mouse species of TLT-2-transduced cells. Human TLT-2 was expressed on freshly isolated, peripheral blood B cells and monocytes, and subpopulations of CD4+ and CD8+ T cells. Human TLT-2 expression on T cells did not correlate with na?ve or memory phenotypes and was diminished after culture, despite the presence of mitogenic stimuli. Constitutive TLT-2 expression on monocytes was also down-regulated after culture. Human B7-H3 transfectants augment IL-2 production from TLT-2-transduced T cell hybridomas, and IFN-γ production from peripheral blood CD4+ and CD8+ T cells. The enhanced responses were inhibited by the addition of anti-TLT-2 mAbs, suggesting TLT-2-mediated costimulatory effect. Our results demonstrate the existence of a functional interaction between human B7-H3 and TLT-2, and the restricted expression of TLT-2 on T cells and monocytes.

关键词： B7-H3 Co-Signal Molecule T Cell TLT-2

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

PROPOSAL OF BREEDING METHOD PREREQUISITE TO VARIETY IDENTIFICATION IN ALLOGAMOUS CROPS,E.G., BUNCHING ONION（ALLIUM FISTULOSUM）

PROPOSAL OF BREEDING METHOD PREREQUISITE TO VARIETY IDENTIFI...

引用

4～(th) International Ishs Symposium on Edible Alliaceae(ISEA)

作者： H.Tsukazaki H.Fukuoka Y.S.Song K.Yamashita A.kojima National Institute of Vegetable and Tea Science National Agricultural Research Organization360 KusawaAno Mie 514-2392 Japan National Institute of Vegetable and Tea Science National Agricultural Research Organization360 KusawaAno Mie 514-2392 Japan National Institute of Vegetable and Tea Science National Agricultural Research Organization 360 Kusawa Ano Mie 514-2392 Japan （Present address）: Mokpo Experiment Station Honam Agricutural Experiment Station RDA 293-5 Chungchun Chunggye Muan Chonnam 534-830 Korea National Institute of Vegetable and Tea Science National Agricultural Research Organization360 Kusawa Ano Mie 514-2392 Japan National Institute of Vegetable and Tea Science National Agricultural Research Organization360 Kusawa Ano Mie 514-2392 Japan

＜正＞ As compared with morphological characters and isozymes, DNA markers can be much more powerful tools for variety identification and also for checking the quality of F1 hybrid seeds. In bunching onion, as in many other vegetable crops, F1 varieties are prevailing in Japan by virtue of their high uniformity in the agronomical traits that breeders take interest in. However, bunching onion is an allogamous crop and therefore thought to hold a degree of genetic heterogeneity within each variety.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

用于保水保肥的聚氨酯泡沫复合材料

引用

材料科学与工程学报 2007年第4期25卷 587-589,597页

作者：刘洁王勇小岛纪德武汉理工大学材料学院湖北武汉430070 日本成蹊大学理工学部物质生命理工学科

用质量比为5∶3的聚醚和甲苯二异氰酸酯反应,制备出聚氨酯软质泡沫。并用此材料作为高分子粘结剂,在聚氨酯发泡过程中加入高性能吸水树脂和缓释化肥,得到一种保水保肥的功能复合材料。研究了聚氨酯软质泡沫材料的配方、吸水树脂和缓释... 详细信息

用质量比为5∶3的聚醚和甲苯二异氰酸酯反应,制备出聚氨酯软质泡沫。并用此材料作为高分子粘结剂,在聚氨酯发泡过程中加入高性能吸水树脂和缓释化肥,得到一种保水保肥的功能复合材料。研究了聚氨酯软质泡沫材料的配方、吸水树脂和缓释化肥加入量及加入到聚氨酯泡沫的时间对复合材料的形貌、吸水率、保水率的影响。通过栽培实验证明该复合材料能够有效地保水保肥和缓释化肥,具有良好的应用前景。

关键词：复合材料聚氨酯泡沫吸水树脂缓释化肥复合

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

感知万物气息之家

引用

现代装饰 2021年第12期 50-57页

作者：日比野拓 Kenjiro Yoshimi Yasu kojima 日比野设计

本案是设计师建于厚木市郊外的个人住宅。比起住在都市,设计师更重视亲近自然的生活方式,能够随时感受到日本的四季,人和事物的动与静;为此,设计师在住宅外部设置了庭院,有意识地注重空间的连通性。庭院和室内的自然过渡和连接在视觉和...

本案是设计师建于厚木市郊外的个人住宅。比起住在都市,设计师更重视亲近自然的生活方式,能够随时感受到日本的四季,人和事物的动与静;为此,设计师在住宅外部设置了庭院,有意识地注重空间的连通性。庭院和室内的自然过渡和连接在视觉和体感层面都得到了体现,设计师对窗户的配置、尺寸、门窗的打开方式,风的流向和采光都有着特别的要求。

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

分布反馈激光器光谱线宽分析

引用

半导体光电 1985年第2期 47-49页

作者： K.kojima K.Kyuma 陈军

分析了分布反馈激光器(DFB)光谱线宽。长腔DFB激光器具有很窄的光谱线宽,如果在腔中心引进相移,那么光谱线宽会进一步变窄。引言:分布反馈(DFB)激光器有可能应用在相干光学通信系统和光纤传感器中,这是因为DFB激光器纵模稳定。对于这样... 详细信息

分析了分布反馈激光器(DFB)光谱线宽。长腔DFB激光器具有很窄的光谱线宽,如果在腔中心引进相移,那么光谱线宽会进一步变窄。引言:分布反馈(DFB)激光器有可能应用在相干光学通信系统和光纤传感器中,这是因为DFB激光器纵模稳定。对于这样应用,激光源的光谱纯度是很重要的;然而,对于DFB激光器,过去只报导了几个实验结果。本文报导了我们给出的DFB激光器光谱

关键词：分布反馈激光器相移 DFB 激光器光谱线宽 DFB

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

天然高分子柿单宁的研究与应用

引用

材料导报 2008年第8期22卷 83-86,98页

作者：王勇邓雷小岛纪德武汉理工大学材料学院武汉430070 日本成磎大学

柿单宁是一种资源丰富、价廉易得的天然高分子材料,是近年来发展迅速的一种环境友好型功能材料,受到愈来愈广泛的重视,并在许多领域得到了应用。叙述了天然高分子柿单宁的制备方法、结构、研究及其应用进展和最新的研究方向。

关键词：柿单宁环境友好功能高分子材料

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：