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An Observational Study on the Clinical and Nutritional Factors Determining the Kidney Function at One Year after Transplantation

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Food and Nutrition Sciences 2018年第11期9卷 1299-1315页

作者： Nao Kawabata Toshiko Sato koji nanmoku Daisuke Nagata Shizukiyo Ishikawa Shun Ishibashi Takashi Yagisawa Yoshio Uehara Department of Clinical Nutrition Jichi Medical University Hospital Shimotsuke Tochigi Japan Graduate School of Home Economics Kyoritsu Women’s University Tokyo Japan Division of Renal Surgery and Transplantation Department of Urology Jichi Medical University Shimotsuke Tochigi Japan Division of Nephrology Department of Internal Medicine Jichi Medical University Shimotsuke Tochigi Japan Medical Education Center Jichi Medical University Shimotsuke Tochigi Japan Division of Endocrinology and Metabolism Department of Internal Medicine Jichi Medical University Shimotsuke Tochigi Japan

Objective: The aim of the present study was to investigate the clinical and nutritional factors influencing the renal function of the transplanted kidney during a one-year follow-up period after transplantation. Patients: The present prospective observational study included 52 patients who underwent kidney transplantation at Jichi Medical University Hospital from 2014 to 2016. Results: The serum creatinine (sCr) concentration at one month after transplantation was closely related to the concentration at 12 months. The recipients were divided into two groups based on the sCr concentration at one month after transplantation. Recipients with a sCr concentration greater than or equal to the median were classified into Group H, while those with concentrations that were less than the median were classified into Group L. A stepwise multiple regression analysis demonstrated that the salt intake in male recipients was an independent predictor of the renal function at 12 months (β = 0.663, p β = 0.618, p < 0.01). Moreover, in female recipients, the BMI and serum uric acid values in Group H were significantly higher than those in Group L. The BMI values of the female recipients in Group H were significantly higher than those in Group L at all times during the follow-up period (p < 0.01). Conclusion: The daily salt intake was independently associated with the renal function at one year after kidney transplantation in male recipients. In female recipients, the BMI was independently associated with the sCr concentration during the one-year follow-up period.

关键词： Salt Obesity Uric Acid Serum Creatinine Kidney Function

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