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Magnetic and magnetocaloric properties in GdZn_(2) synthesized by ball milling

Journal of Rare Earths 2022年第3期40卷 462-466,I0004页

作者： Keisuke T.Matsumoto Akihiro Hosokawa koichi hiraoka Graduate School of Science and Engineering Ehime University3Bunkyo-choMatsuyamaEhime790-8577Japan

In this study,we prepared GdZn_(2)by mechanical alloying method and measured its magnetization to reveal the magnetic and magnetocaloric properties.For a milling time(MT)≥10 and 20 h,the GdZn_(2)phase was confirmed by X-ray diffraction measurements.For MT=40 and 60 h,amorphous like patterns are observed.For MT=10 and 20 h,magnetization(M)as a function of temperature below 80 K shows ferromagnetic-like increase.The observed values of M are 4.5μ_(B) at 5 K for MT=10 and 20 h,which is smaller than that of the theoretical expected value of 7μ_(B).For MT=40 and 60 h,the long-range ferromagnetic order collapses because there is no spontaneous magnetization.The value ofΔT,whereΔT is the full width at half maximum of the magnetic entropy change(ΔS_(m)(T)),increases significantly for MT≤20 h because of the gradual release of magnetic entropy by the milling effect.Since M decreases with increasing MT,the maximum values of|ΔS_(m)|,the relative cooling power,and the refrigerant capacity also decreases.

关键词： Mechanical alloying Magnetocaloric effect GdZn_(2) Rare earths

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Experimental Study of Condensation Heat Transfer on Tube Bundles in Large Power Plant Condensers

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Journal of Energy and Power Engineering 2014年第5期8卷 920-928页

作者： koichi Inoue Issaku Fujita Kotaro Machii Satoshi hiraoka Manabu Ishihara Faculty of Environmental Engineering The University of Kitakyushu Fukuoka 8080135 Japan Takasago Machinery Works Mitsubishi Heavy Industries Ltd. Hyogo 6768686 Japan

In order to clarify the effect of condensate inundation on steam condensation in a large tube bundle, condensation heat transfer and the condensate flow pattern in the tube bundle have been experimentally investigated. Test tube bundle consists of 36 cooling tubes, 12 condensate supply tubes and 24 un-cooled dummy tubes. Cooling test tubes are made of copper and have an outer diameter of 19.1 mm and condensing length of 150 mm. Steam flows horizontally through the test tube bundle at gap velocities 15-27 m/s at pressures of 8.8 kPa. In this study, experimental data about condensate flow pattern and condensation heat transfer in a tube bundle were collected for the optimization of tube arrangement in large power plant condensers.

关键词：实验数据冷凝器管束大型电厂冷凝换热蒸汽冷凝冷凝传热大型发电厂

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A Human T Lymphotropic Virus Type 1 Carrier Coinfected with <i>Mycobacterium intracellulare</i>and <i>Pneumocystis jirovecii</i>with a Characteristic Compositional Change of Bone Marrow Cells

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Open Journal of Respiratory Diseases 2017年第3期7卷 110-116页

作者： Sayaka Uda Shinsuke Shiotsu Ayaka Omura Ryosuke Hamashima Akihiro Yoshimura Naoko Kurisu Tomoya Sagawa koichi Hasegawa Tatsuya Yuba Chieko Takumi Seiko Ono Noriya hiraoka Noriya hiraoka Department of Respiratory Medicine Japanese Red Cross Kyoto Daiichi HospitalKyotoJapan Department of Respiratory Medicine Graduate School of MedicineKyoto UniversityKyotoJapan Department of Infection Control and Prevention Japanese Red Cross Kyoto Daiichi HospitalKyotoJapan

Human T lymphotropic virus type 1 (HTLV-1) is endemic in the southern part of Japan. Infection of the virus can cause adult T cell leukemia/lymphoma (ATL), while most infected individuals remain in a carrier state for a long period of time. Although rare cases of carriers, like ATL patients, who developed opportunistic infections, have been reported, hematological changes of carriers who are prone to opportunistic infections have not been well defined. Here, we present a case of an HTLV-1 carrier who developed Mycobacterium intracellulare infection and Pneumocystis jirovecii pneumonia (PcP) simultaneously. Flow cytometric analysis of bone marrow cells revealed an aberrant compositional change similar to that in ATL patients. This suggests the presence of a pre-ATL state prior to the development of ATL, which is notable in terms of underlying cellular immunodeficiency.

关键词： Human T Lymphotropic Virus Type 1 Carrier Immunodeficiency Pneumocystis jirovecii

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雷莫芦单抗用于经乐伐替尼治疗后进展的不可切除肝细胞癌的治疗效果

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Gastroenterology Report 2021年第2期9卷 133-138,I0002页

作者： Atsushi hiraoka Takashi Kumada Toshifumi Tada Chikara Ogawa Joji Tani Shinya Fukunishi Masanori Atsukawa Masashi Hirooka Kunihiko Tsuji Toru Ishikawa koichi Takaguchi Kazuya Kariyama Ei Itobayashi Kazuto Tajiri Noritomo Shimada Hiroshi Shibata Hironori Ochi Kazuhito Kawata Hidenori Toyoda Hideko Ohama Kazuhiro Nouso Akemi Tsutsui Takuya Nagano Norio Itokawa Korenobu Hayama Taeang Arai Michitaka Imai Yohei Koizumi Shinichiro Nakamura Kojiro Michitaka Yoichi Hiasa Masatoshi Kudo Gastroenterology Center Ehime Prefectural Central HospitalEhimeJapan Department of Gastroenterology and Hepatology Ogaki Municipal HospitalGifuJapan Department of Internal Medicine Himeji Red Cross HospitalHyogoJapan Department of Gastroenterology and Hepatology Takamatsu Red Cross HospitalTakamatsuJapan Department of Gastroenterology and Hepatology Kagawa universityKagawaJapan Department of Gastroenterology Osaka Medical CollegeOsakaJapan Division of Gastroenterology and Hepatology Department of Internal MedicineNippon Medical SchoolTokyoJapan Department of Gastroenterology and Metabology Ehime University Graduate School of MedicineEhimeJapan Center of Gastroenterology Teine Keijinkai HospitalSapporoJapan Department of Gastroenterology Saiseikai Niigata HospitalNiigataJapan Department of Hepatology Kagawa Prefectural Central HospitalTakamatsuJapan Department of Gastroenterology Okayama City HospitalOkayamaJapan Department of Gastroenterology Asahi General HospitalAsahiJapan Department of Gastroenterology Toyama University HospitalToyamaJapan Division of Gastroenterology and Hepatology Otakanomori HospitalKashiwaJapan Department of Gastroenterology Tokushima Prefectural Central HospitalTokushimaJapan Hepato-biliary Center Matsuyama Red Cross HospitalMatsuyamaJapan Department of Hepatology Hamamatsu University School of MedicineHamamatsuJapan Department of Gastroenterology Kindai UniversityOsakaJapan

背景:在日本,乐伐替尼可用于不可切除原发性肝癌的一线、二线或三线治疗。本研究评估新近研发的雷莫芦单抗用于经乐伐替尼治疗后进展的不可切除的原发性肝癌的疗效。方法:2018年5月至2020年1月间在日本16家中心接受乐伐替尼治疗的385例... 详细信息

背景:在日本,乐伐替尼可用于不可切除原发性肝癌的一线、二线或三线治疗。本研究评估新近研发的雷莫芦单抗用于经乐伐替尼治疗后进展的不可切除的原发性肝癌的疗效。方法:2018年5月至2020年1月间在日本16家中心接受乐伐替尼治疗的385例不可切除原发性肝癌患者中,我们将其中接受雷莫芦单抗作为下一线治疗的28例患者纳入研究,对其治疗效果进行回顾性分析。结果:28例患者中位年龄70岁,中位白蛋白-胆红素(ALBI)评分为2.19。28例患者中,23例为男性;21例为Child-Pugh A级,7例为Child-Pugh B级;3例为BCLC B期,25例为BCLC C期。雷莫芦单抗用于二线、三线和四线治疗的病例分别为14例、9例和5例患者。26例患者获得疗效评估,客观缓解率为3.8%(1/26),疾病控制率为42.3%(11/26);中位疾病进展时间为2个月。未继续接受雷莫芦单抗治疗的原因包括16例出现疾病进展和2例出现3级不良反应(消化道出血和腹水)。结论:我们的初步研究显示,对于乐伐替尼治疗进展的不可切除原发性肝癌,雷莫芦单抗并没有获得预期的治疗效果。

关键词： hepatocellular carcinoma ramucirumab lenvatinib sorafenib

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