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严重主动脉瓣狭窄病人无椭圆形收缩孔的融合主动脉瓣:心脏CT对区分有缝的二叶主动脉瓣与合缝处融合的三叶主动脉瓣有帮助

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国际医学放射学杂志 2015年第3期 306-306页

作者： S.H.Bak S.M.ko M.G.Song J.K.Shin H.K.Chee J.S.Kim 刘义涛 Department of Radiology Konkuk University Medical Center konkuk University School of Medicine 4-12 Hwayang-dongGwangjin-gu Seoul 143-729Korea konkuk University School of Medicine 4-12 Hwayang-dongGwangjin-gu Seoul 143-729Korea

目的确定心脏CT(CCT)能够区分伴有融合瓣尖和无椭圆形收缩孔的严重主动脉瓣狭窄(AS)病人的二叶主动脉瓣(BAV)与三叶主动脉瓣(TAV)的特征。方法回顾性

关键词：主动脉瓣狭窄 CT 病人三叶心脏

韩国抗大豆拟茎点种腐病(Phomopsis longicolla)的大豆品种评价

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大豆科技 2014年第5期 28-28页

作者： Suli Sun Kyujung Van Moon Young Kim Yeong-Ho Lee Jong-Min ko in-Youl Baek Yin-Won Lee Weixian Liu Suk-Ha Lee Baek Suk-Ha Lee 李雪光

大豆拟茎点种腐病（PSO），主要由Phomopsis longicolla引起的，是大豆重要种传病害之一，造成大豆产量严重损失。该研究评价了韩国主要大豆栽培品种对***的抗性，这些主栽品种主要用于亲本基因图谱绘制。2009--2010年间在韩国3个不同... 详细信息

大豆拟茎点种腐病（PSO），主要由Phomopsis longicolla引起的，是大豆重要种传病害之一，造成大豆产量严重损失。该研究评价了韩国主要大豆栽培品种对***的抗性，这些主栽品种主要用于亲本基因图谱绘制。2009--2010年间在韩国3个不同地点测定了田间自然发病条件下***和其他3种种传真菌的发病率。研究显示被测大豆品种对种传病害敏感性差异明显。品种Tae—kwangkong表现对***最大的抗性，平均发病率仅为0．33％，其他种传真菌平均发生率为6．17％。此外，在密阳（Milyang）和大邱（Daegu），品种Taekwangkong没有受到***0ngicolla的侵染。

关键词：大豆产量品种评价种腐病韩国茎种传病害种传真菌敏感性差异

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聚有机硅氧烷的研究——Ⅳ.碱对聚二甲基硅氧烷交联的影响

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高分子通讯 1964年第5期 382-384页

作者：江英彦李玉福卢英伟林一中国科学院化学研究所中国科学技术大学中国科学院化学研究所 1963年毕业生

高分子量的线型聚二甲基硅氧烷,即硅橡胶,可用八甲基环四硅氧烷（简称D4）在适当催化剂下进行开环聚合。工业上普遍采用的聚合催化剂是氫氧化鉀。为了使催化剂能够均匀地分散在D4中,可将氫氧化鉀和适量的D4先行反应,形成合碱量較大的低... 详细信息

高分子量的线型聚二甲基硅氧烷,即硅橡胶,可用八甲基环四硅氧烷（简称D4）在适当催化剂下进行开环聚合。工业上普遍采用的聚合催化剂是氫氧化鉀。为了使催化剂能够均匀地分散在D4中,可将氫氧化鉀和适量的D4先行反应,形成合碱量較大的低分子量的聚二甲基硅氧烷（简称碱胶）,然后以这种碱胶作为催化剂使D4聚合。

关键词：聚二甲基硅氧烷有机硅氧烷交联

Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma

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Signal Transduction and Targeted Therapy 2023年第5期8卷 2329-2344页

作者： Junhui Hu Ping Tan Moe ishihara Nicholas ABayley Shiruyeh Schokrpur Jeremy GReynoso Yangjun Zhang Raymond JLim Camelia Dumitras Lu Yang Steven MDubinett Parmjit SJat Jacques Van Snick Jiaoti Huang Arnold iChin Robert MPrins Thomas GGraeber Hua Xu Lily Wu Department of Molecular and Medical Pharmacology David Geffen School of MedicineUniversity of California Los AngelesLos AngelesCA90095USA Department of Urology West China HospitalChengduChina Department of Hematology and Oncology University of California San DiegoSan DiegoCA92103USA Department of Neurosurgery David Geffen School of MedicineUniversity of California Los AngelesLos AngelesCA90095USA Department of Biological Repositories Department of UrologyZhongnan Hospital of Wuhan UniversityWuhanChina Department of Medicine David Geffen School of MedicineUniversity of California Los AngelesLos AngelesCA90095USA Jonsson Comprehensive Cancer Center David Geffen School of Medicine at UCLAUniversity of California Los AngelesLos AngelesCA90095USA MRC Prion Unit at UCL Institute of Prion Diseases33 Cleveland StreetLondonW1W 7FFUK Ludwig institute for Cancer Research Ltd BrusselsBelgium Department of Pathology Duke UniversityDurhamNCUSA Department of Urology David Geffen School of MedicineUniversity of California Los AngelesLos AngelesCA90095USA Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center WuhanChina

Loss of function of the von Hippel-Lindau(VHL)tumor suppressor gene is a hallmark of clear cell renal cell carcinoma(ccRCC).The importance of heterogeneity in the loss of this tumor suppressor has been under *** study the impact of intratumoral VHL heterogeneity observed in human ccRCC,we engineered VHL gene deletion in four RCC models,including a new primary tumor cell line derived from an aggressive metastatic *** VHL gene-deleted(VHL-ko)cells underwent epithelial-to-mesenchymal transition(EMT)and exhibited increased motility but diminished proliferation and tumorigenicity compared to the parental VHL-expressing(VHL+)*** tumors with either VHL+or VHL-ko cells alone exhibit minimal metastatic *** tumors displayed rampant lung metastases,highlighting a novel cooperative metastatic *** poorly proliferative VHL-ko cells stimulated the proliferation,EMT,and motility of neighboring VHL+***(POSTN),a soluble protein overexpressed and secreted by VHL non-expressing(VHL−)cells,promoted metastasis by enhancing the motility of VHL-WT cells and facilitating tumor cell vascular *** deletion or antibody blockade of POSTN dramatically suppressed lung metastases in our preclinical *** work supports a new strategy to halt the progression of ccRCC by disrupting the critical metastatic crosstalk between heterogeneous cell populations within a tumor.

关键词： VHL metastasis motility

前扣带皮层两种形式LTP的突触机制揭示焦虑和慢性疼痛相互作用

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科学新闻 2016年第1期 74-74页

作者： kohei koga Giannina Descalzi 陈涛 Hyoung-Gon ko Jinshan Lu Shermaine Li Junehee Son TaeHyun Kim Chuljung Kwak Richard L.Huganir 招明高 Bong-Kiun Kaang Graham L.Collingridge 卓敏日本Alima大学西安交通大学美国约翰·霍普金斯大学韩国国立大学英国布里斯托大学西安交通大学前沿科学技术研究院神经和疾病研究中心加拿大皇家科学院

文章简介慢性疼痛可导致焦虑,焦虑能增强痛觉。不幸的是,对这些现象的关联的基本神经机制了解很少。在这篇文章里,研究发现了和痛/焦虑相关的ACC有两种完全不同的长期可塑性(LTP):突触前和突触后。突触前LTP需要有腺苷酸环化酶和蛋白激... 详细信息

文章简介慢性疼痛可导致焦虑,焦虑能增强痛觉。不幸的是,对这些现象的关联的基本神经机制了解很少。在这篇文章里,研究发现了和痛/焦虑相关的ACC有两种完全不同的长期可塑性(LTP):突触前和突触后。突触前LTP需要有腺苷酸环化酶和蛋白激酶A的参与,而它的表达是通过一种机制涉及超极化激活环核苷酸门控通道(HCN)。有趣的是,慢性疼痛和焦虑都能选择性抑制突触前LTP。更重要的,将HCN的阻滞剂

关键词：慢性疼痛突触前 LTP 两种

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粤東沿海地區海豐、陸豐兩縣絲蟲病調查報告

微生物学报 1958年第3期 345-352页

作者：陳心陶徐秉錕蔡尚達陳維亮柯小麟蘇克勤何桂銘劉德山余炳楨容瓘勞綺雲鄺麗賢中山医学院寄生虫学教研组

海豐和陸豐是廣東的兩個沿海縣份,屬於亞熱帶氣候的沿海地區,日夜受海風的直接影響,空氣中的相對濕度很大,全年雨量平均在1300毫米以上。但在另一方面,佔兩縣很大一部分面積的海邊地帶,土地是比較瘦瘠,加上每年的風災、水災,農民生活本... 详细信息

海豐和陸豐是廣東的兩個沿海縣份,屬於亞熱帶氣候的沿海地區,日夜受海風的直接影響,空氣中的相對濕度很大,全年雨量平均在1300毫米以上。但在另一方面,佔兩縣很大一部分面積的海邊地帶,土地是比較瘦瘠,加上每年的風災、水災,農民生活本來就是比較貧困的;更由於這裏是老革命根據地,國民黨的破壞和掠奪特別殘酷,使得長期以來,田園荒芜,百業不振,農民生活十分困苦。解放之後,雖然根本改變了過去的面貌,但在我們

关键词：感染期银瓶山感染率库蚊库蚊属南塘蚊子胸肌代表性

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas konstantin Afanaciev Shakeel Ahmad ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi igor Boyko ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research institute Co. LtdBeijing Beijing institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong kong Department of PhysicsHong Kong Cockcroft institute Daresbury Cornell University IthacaNY CPPM(AMU/iPhU&CNRS/iNP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint institute for Nuclear Research(DLNP JiNR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(iP),resulting in an integrated luminosity of 13 ab^(-1)for two iPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise