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Choroidal neovascularization and angioid streaks in pseudoxanthoma elasticum

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International Journal of Ophthalmology(English edition) 2011年第4期4卷 449-451页

作者： melisa nika Cagri G besirli Department of Ophthalmology and Visual Sciences University of Michigan Medical School Ann Arbor Michigan Kellogg Eye Center

AIm: To report a case of pseudoxanthoma elasticum (PXE) in a 48 year old woman that presented with bilateral blurry vision. mETHODS: A case report RESULTS: A 48-year-old woman presented with bilateral blurry vision and right eye metamorphopsia. The patient had a history of angioid streaks in the left eye ten years ago for which she had received laser surgery and had poor residual vision. Visual acuity was 20/60 in the right eye and count fingers at 6 feet in the left. Fundus examination showed subretinal hemorrhage and macular thickening on the right and a disciform macular scar with focal atrophic pigment epithelial lesions on the left. both eyes had angioid streaks and peau d’orange pigmentary pattern of the retina. External examination showed several, yellow skin papules and plaques on the lateral and posterior neck, as well as prominent mental creases. Pathologic examination of skin biopsy confirmed the diagnosis of PXE, showing calcium deposition and fragmented, clumped elastic fibers in the deep reticular dermis. She responded well to intravitreal bevacizumab injections and visual acuity improved to 20/25 OD. Preventative care was emphasized and the patient was referred to cardiology, gastroenterology and human genetics for counseling. CONCLUSION: PXE is a multisystem disorder affecting the dermatologic, ocular, and cardiovascular systems. Ophthalmic findings of angioid streaks and choroidal neovascularization in the presence of stereotypical skin changes and prominent mental creases should prompt evaluation for PXE.

关键词： angioid streaks pseudoxanthoma elasticum peau d'orange

Structure and Properties of Electroless Ni Deposits

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Journal of materials Science & Technology 1996年第5期12卷 342-346页

作者： Zhang, YZ Sun, kn Wu, YY Zhang, JW Yao, m YANSHAN UNIV DEPT MAT SCI & ENGNQINHUANGDAO 066004PEOPLES R CHINA

The changes in structure and the hardness of two electroless deposited Ni-P alloy coatings (with P content of 1.5 and 9.5 wt pet) with heat treatment have been studied by XRD and TEm. The deposits containing 1.5 wt pet P can be represented as an fee NiP supersaturated solid solution of 5 similar to 10 nm microcrystallites, whereas the deposits containing 9.5 wt pet P are amorphous. The heat treatment process induces crystallization of amorphous Ni to Ni phosphides and fee Ni. both of the deposits reach maximum hardness after annealing at 400 degrees C for 1 h. All coated steel specimens are inferior in fatigue strength to uncoated steel specimens mainly due to the poor fatigue resistance of the coating itself.

关键词： Coatings

Neuroinflammation revisited through the microglial lens

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Neural Regeneration Research 2025年第7期20卷 1989-1990页

作者： Renato Socodato João b.Relvas Institute of Research and Innovation in Health(i3S)and Institute for molecular and Cell biology(IbmC) University of PortoPortoPortugal Department of biomedicine Faculty of Medicine of the University of Porto(FMUP)PortoPortugal

Neuroimmunology is emerging as a pivotal field,shedding light on the intricate dialogues between the central nervous system(CNS)and the immune *** exploration is particularly significant in understanding microglia,the CNS’s innate immune cells,beyond the conventional conflation of“neuroinflammation”and“microglial activation.”This conflation has clouded the true complexity of these processes,potentially stalling scientific progress and the development of new *** challenge the long-standing perspectives that have oversimplified these interactions,advocating for a deeper exploration of the dynamic relationship between neuroinflammation and microglial *** dissecting specific molecular pathways,we aim to illuminate their elaborate roles in neuroinflammatory responses,especially in the context of Alzheimer’s disease(AD).Here,neuroinflammation is not merely a passive observer or a direct antagonist but a complex agent in the disease’s *** article calls for a significant paradigm shift towards an integrative,multi-omics approach to *** such a comprehensive framework is crucial for advancing our understanding of neuroinflammatory conditions and paving the way for targeted therapeutic strategies for brain diseases.

关键词： inflammation simplified activation

Statistical Characteristics of the Temporal Spectrum of Scattered Radiation in the Equatorial Ionosphere

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Journal of Environmental & Earth Sciences 2023年第1期5卷 85-94页

作者： George Jandieri nika Tugushi 1VSb-Technical University of Ostrava Ostrava70800Czech Republic Tbilisi State University Tbilisi0128Georgia

On the basis of the solution of the space-time characteristic system by the method of geometric optics using symbolic calculations,analytical and numerical simulation of the propagation of the ordinary and extraordinary radio waves in the conducting equatorial ionospheric plasma was made considering the anisotropy of plasma irregularities and non-stationary nature of propagation *** of the spectrum and the displacement of its maximum contain velocity of a turbulent plasma flow and parameters characterizing anisotropic plasmonic *** moments of both radio waves do not depend on the absorption sign and are valid for both active and absorptive random *** pulsations and conductivity of a turbulent ionospheric plasma have an influence on the evaluation of the spectrum-varying propagation distances travelling by these *** new double-humped effect in the temporal spectrum has been revealed for the ordinary wave varying anisotropy coefficient and dip angle of stretched plasmonic *** a theoretical point of view,the algorithms developed in this work allow effective modelling of the propagation of both radio signals in the equatorial conductive ionospheric plasma,considering the external magnetic field,inhomogeneities of electron density in-homogeneities,as well as non-stationary.

关键词： Electromagnetic waves Turbulence Statistical characteristics Waves propagation Atmosphere Ionosphere Conductivity

Nonlinear forced vibration in a subcritical regime of a porous functionally graded pipe conveying fluid with a retaining clip

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 101-122页

作者： m.GHOLAmI m.EFTEKHARI Department of mechanical Engineering Shahid Bahonar University of Kerman

This study examines the nonlinear behaviors of a clamped-clamped porous pipe made of a functionally graded material(FGm) that conveys fluids and is equipped with a retaining clip, focusing on primary resonance and subcritical dynamics. The nonlinear governing equations for the FGm pipe are derived by the extended Hamilton's principle, and subsequently discretized through the application of the Galerkin *** direct method of multi-scales is then used to solve the derived equations. A thorough analysis of various parameters, including the clip stiffness, the power-law index, the porosity, and the clip location, is conducted to gain a comprehensive understanding of the system's nonlinear dynamics. Through the analysis of the first natural frequency, the study highlights the influence of the flow velocity and the clip stiffness, while the comparisons with metallic pipes emphasize the role of FGm composition. The examination of the forced response curves reveals saddle-node bifurcations and their dependence on parameters such as the detuning parameter and the power-law index, offering valuable insights into the system's nonlinear resonant behavior. Furthermore, the frequency-response curves illustrate the hardening nonlinearities influenced by factors such as the porosity and the clip stiffness, revealing nuanced effects on the system response and resonance characteristics. This comprehensive analysis enhances the understanding of nonlinear behaviors in FGm porous pipes with a retaining clip, providing key insights for practical engineering applications in system design and optimization.

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The potential application of red mud and soil mixture as additive to the surface layer of a landfill cover system

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Journal of Environmental Sciences 2016年第6期28卷 189-196页

作者： Eva Ujaczki Viktória Feigl mónika molnár Emese Vaszita Nikolett Uzinger Attila Erdélyi Katalin Gruiz Department of Applied biotechnology and Food Science Faculty of Chemical Technology and Biotechnology Budapest University of Technology and Economics H-1111 Budapest Muegyetem rkp. 3 Hungar Institute for Soil Sciences and Agricultural Chemistry Centre for Agricultural Research Hungarian Academy of Sciences H-1022 Budapest Herman Otto Street 15 Hungary A.S.A. Hungary Ltd. H-2360 Gydl Karosi Street 53 Hungary

Red mud, the by-product of aluminum production, has been regarded as a problematic residue all over the world. Its storage involves risks as evidenced by the Ajka red mud spill,an accident in Hungary where the slurry broke free, flooding the surrounding areas. As an immediate remediation measure more than 5 cm thick red mud layer was removed from the flooded soil surface. The removed red mud and soil mixture（RmSm） was transferred into the reservoirs for storage. In this paper the application of RmSm is evaluated in a field study aiming at re-utilizing waste, decreasing cost of waste disposal and providing a value-added product. The purpose was to investigate the applicability of RmSm as surface layer component of landfill cover systems. The field study was carried out in two steps： in lysimeters and in field plots. The RmSm was mixed at ratios ranging between 0 and 50% w/w with low quality subsoil（LQS） originally used as surface layer of an interim landfill cover. The characteristics of the LQS ＋ RmSm mixtures compared to the subsoil（LQS） and the RmSm were determined by physical–chemical, biological and ecotoxicological methods. The addition of RmSm to the subsoil（LQS） at up to 20% did not result any ecotoxic effect, but it increased the water holding capacity. In addition, the microbial substrate utilization became about triple of subsoil（LQS） after 10 months. According to our results the RmSm mixed into subsoil（LQS） at20% w/w dose may be applied as surface layer of landfill cover systems.

关键词： Red mud Soil amelioration Environmental toxicology Landfill cover constituent Field-study Lysimeter

Thermal transport in semiconductor nanostructures, graphene,and related two-dimensional materials

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Chinese Physics b 2018年第5期27卷 74-82页

作者： Alexandr I.Cocemasov Calina I.Isacova Denis L.nika E.Pokatilov Laboratory of Physics and Engineering of Nanomaterials Department of Physics and EngineeringMoldova State University

We review experimental and theoretical results on thermal transport in semiconductor nanostructures（multilayer thin films, core/shell and segmented nanowires）, single-and few-layer graphene, hexagonal boron nitride, molybdenum disulfide, and black phosphorus. Different possibilities of phonon engineering for optimization of electrical and heat conductions are discussed. The role of the phonon energy spectra modification on the thermal conductivity in semiconductor nanostructures is revealed. The dependence of thermal conductivity in graphene and related two-dimensional（2 D） materials on temperature, flake size, defect concentration, edge roughness, and strain is analyzed.

关键词： phonons thermal conductivity nanowire graphene two-dimensional (2D) materials

Preventing Health Anxiety:The Role of Self-Evaluation,Sense of Coherence,Self-Rated Health and Perceived Social Support

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International Journal of mental Health Promotion 2023年第10期25卷 1081-1088页

作者： Sándor Csibi mónika Csibi József bognár Department of Sport Sciences Eszterházy Károly Catholic UniversityEger3300Hungary Department of Special Needs Education Eszterházy Károly Catholic UniversityEger3300Hungary

background:Components of Self,completed with the perceived social support determine the individual differences in theevaluation of a stressor and the behavioral responses toward it,such as health-related *** study set as a goal theanalysis of associations between the components of Self,such as self-evaluation,sense of coherence,perceived social support,and reported health-related anxiety in an adult ***:147 adults from the 18–73 age group(mean age 37.5)voluntarily completed the questionnaire through Qualtrics online platform containing the Short Health Anxiety Inventory,Core Self-Evaluation Scale,Social Support Assessing Scale,and one Health Self-Evaluation ***:ANOVA foundrelevant differences in total scores and subscales’scores of the health anxiety scale depending on the positive *** regression shows that the analyzed variables were responsible for the prediction of a higher value on the“Perceivedprobability of becoming ill”subscale in a proportion of 45.6%and for the“Perceived consequence of illness”subscale in aproportion of 20.2%The predictive value of the linear regression model for the total score on the health anxiety scale was46.3%.Our findings show that negative Core Self-Evaluation is linked with perceived health ***:Selfevaluation,sense of coherence and perceived social support influence the perceived health and can explain the differences inthe reported health-related anxiety.

关键词： Core self-evaluation health anxiety health self-evaluation perceived social support self-concept the sense of coherence

Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity

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Neural Regeneration Research 2025年第6期20卷 1565-1581页

作者： moawiah m.Naffaa Department of Psychology and Neuroscience Duke UniversityDurhamNCUSA Department of Cell biology Duke University School of MedicineDurhamNCUSA

Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. The generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit remodeling triggered by memory and learning processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. moreover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory information processing. This adaptive process responds to changes in epithelial composition and contributes to the formation of olfactory memories by modulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. The role of adult neurogenesis in olfactory bulb functions remains a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around mitral and tufted cells. This organizational pattern significantly impacts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and memory. Additionally, this organization is further shaped by axon terminals originating from cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these complex and highly interconnected processes have not been comprehensively studied as a whole. Therefore, this manuscript aims to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. These mechanisms are thought to support olfactory learning and memory, potentially through increased

关键词： network adaptability neurogenesis neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity