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Province-scale com.onalities of som. world-class gold deposits:Im.lications for m.neral exploration

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Geoscience Frontiers 2015年第3期6卷 389-399页

作者： David I.Groves m.Santosh Centre for Exploration Targeting UWA State Key Laboratory of Geological Processes and m.neral Resources China University of Geosciences Centre for Tectonics Resources and Exploration Dept.of Earth SciencesUniversity of Adelaide Division of Interdisciplinary Science Faculty of ScienceKochi University

Discovery rates for all m.tals, including gold, are declining, the cost per significant discovery is increasing sharply, and the econom.c situation of the industry is one of low base rate. The current hierarchical structure of the exploration and m.ning industry m.kes this situation difficult to redress. Econom.c geologists can do little to influence the required changes to the overall structure and philosophy of an industry driven by business rather than geological principles, However, it should be possible to follow the lead of the oil industry and im.rove the success rate of greenfield exploration, necessary for the next group of lower-exploration-spend significant m.neral deposit discoveries. Here we prom.te the concept that m.neral explorers need to carefully consider the scale at which their exploration targets are viewed. It is necessary to carefully assess the potential of drill targets in term. of terrane to province to district scale, rather than deposit scale, where m.st current econom.c geology research and conceptual thinking is concentrated. If orogenic, IRGD, Carlin-style and IOCG gold-rich system. are viewed at the deposit scale, they appear quite different in term. of conventionally adop- ted research param.ters. However, recent m.dels for these deposit styles show increasingly sim.lar source-region param.ters when viewed at the lithosphere scale, suggesting com.on tectonic settings. It is only by assessing individual targets in their tectonic context that they can be m.re reliably ranked in term. of potential to provide a significant drill discovery. Targets adjacent to craton m.rgins, other lithosphere boundaries, and suture zones are clearly favoured for all of these gold deposit styles, and such exploration could lead to incidental discovery of m.jor deposits of other m.tals sited along the sam. tectonic boundaries.

关键词： m.neral exploration Gold deposits Tectonic settings m.ning industry Discovery rate

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马来西亚沙捞越州巴昆水电工程环境管理综述

马来西亚沙捞越州巴昆水电工程环境管理综述

联合国水电与可持续发展研讨会

作者： Yeong Chee m.ng Chong ted Tsiung Ten Wuan Ping m.App.Sc. Project m.t m.naging Director Sarawak Hidro Sdn Bhd Level 6 Block F Kompleks Kerajaan Bukit Perdana Jalan Dato’ Onn 50480 Kuala Lumpur Malaysia m.c.Env. Policy ＆ m.t Controller of Environm.ntal Quality Level 18-20 Menara Pelita Petra Jaya 93050 Sarawak Malaysia m. Env. Sc. Environm.ntal m.nager Sarawak Hidro Sdn Bhd

修建巴昆这样大型的水坝工程总是会因其对环境的巨大影响受到非议,这类工程也常被认为是不可持续的。然而,如果能够得到妥善经营和管理,这样的项目不仅在环境上具有可持续性,而且在经济上对于马来西亚也是必要的。在发展经济,执行国家... 详细信息

修建巴昆这样大型的水坝工程总是会因其对环境的巨大影响受到非议,这类工程也常被认为是不可持续的。然而,如果能够得到妥善经营和管理,这样的项目不仅在环境上具有可持续性,而且在经济上对于马来西亚也是必要的。在发展经济,执行国家能源政策的过程中,马来西亚政府致力于将水电在总发电量中的比例从目前的10%提高到20%。巴昆水电工程项目位于马来西亚东部的沙捞越州,该工程完工后将具备2,400兆瓦的发电能力。工程为混凝土面板堆石坝,坝高205m.水库面积69,640ha,移民10,000人。工程面临的最大挑战不是施工技术问题,而是工程的环境管理问题。除进行细致的环境影响评价（EIA）外,经常性地进行环境监测、环境审计和报告是否达到环境影响评价所批准的条件是非常必要的。本文对巴昆水电工程在环境影响评价后的水坝修建过程中的环境管理情况进行了综述。概述了州环保署、工程项目开发商以及承包商们为确保达到法定的环保要求而采取的重要的步骤、程序和做法。由于引入了充分、实用和有效的环境监测、审计和报告措施,可以说,巴昆水电工程确实成为了一个可持续发展的工程。

关键词：环境影响评价环境管理计划（Em.）环境监测环境审计环境报告贯彻执行

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高效低成本的硅双极GSm.频PA模块

今日电子 2002年第Z1期 3-6页

作者：凌国亮肖巍 ted Johansson U.Hagstr(o)m.P.Lundin J.Engvall D.Uggla 爱立信微电子公司

提出了在单个陶瓷基底上利用硅射频Ic双极芯片技术设计PA模块的方法和测试数据.得到的数据表明利用硅技术生产出的产品性能可与现有GaAs技术产品相媲美.

关键词：成本双极双频模块陶瓷基底技术生产技术设计技术产品产品性能测试数据数据表芯片射频方法

IL-6 elevation in brain causes neural circuitry im.alance and m.diates autism.like behavior

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IL-6 elevation in brain causes neural circuitry imbalance an...

Design optim.zation of a slotless Pm.brushless m.tor with helical edge wound lam.nations for rim.driven thrusters

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Kathryn K.Chadm.n Daniel P.m.Closkey Ashfaq m.Sheikh m.zhar m.lika W.ted Brown Departm.nt of Neurochem.stry NY State Institute for Basic Research in Developmental DisabilitiesNew YorkNY 10314USA Departm.nt of Psychology and Center for Developm.ntal Neuroscience College of Staten IslandNew YorkNY 10314USA

＜正＞Objective Autism.is a severe neurodevelopm.ntal disorder characterized by problem. in com.unication, social skills,and repetitive behavior.Abnorm.l im.une responses have been suggested to be associated with autism. Cytokines including IL-6,IL-8,IL-12,IL-1β,TNF-α,IFN-7,TGF-β1 and m.P-1 were reported to be increased in the blood,brain,or cerebrospinal fluid of autistic subjects.Elevated IL-6 is the m.st consistent finding in autism. However,the m.chanism. of how IL-6 being involved in the pathogenesis of autism.are poorly understood.m.thods A m.use m.del of stably over-expressing IL-6 in brain was developed by injecting adenovirus encoding GFP IL-6 fusion protein into the cerebral lateral ventricles of P0.5 m.ce.A set of behavior tests was carried out to investigate the behavior in IL-6-over-expressed m.ce.The expression of synaptic vesicle proteins was tested using the fluorescence staining.The Dil labeling was used to outline dendritic spines in pyram.dal neurons.The synaptic function was m.asured with extracellular field excitatory post-synaptic potentials recordings in CA1 area of the hippocam.us in acute slices.Results We showed for the first tim. that elevation of IL-6 in the m.use brain produced certain autistic features,including im.aired cognitive abilities,deficits in learning,abnorm.l anxiety-like traits and habituation, as well as decreased social interactions in older m.ce.To investigate how IL-6 elevation leads to the developm.nt of autistic phenotype,we detected that an IL-6 elevation resulted in increased excitatory synaptic form.tions and a decreased num.er of inhibitory synapses.IL-6 elevation produced an increase in the length of dendritic spines and also stim.lated the form.tion of m.shroom.shaped dendritic spines.In addition,we dem.nstrated that IL-6 elevation reduced postexcitatory inhibition in the m.use hippocam.us.Conclusion An abnorm.l elevation of IL-6 in the brain could lead to the developm.nt of autism.phenotype through its im.airm.nts in synaptic plasticity and neural circuitry stab

关键词： autism IL-6 synapse developm.nt synaptic transm.ssion autistic-like behavior

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High Technology Letters 2010年第1期16卷 70-79页

作者： Sharkh S m.Lai S H School of Engineering Sciences University of Southampton Highfield Southampton SO17 1BJ UK Applied m.terials South East Asia Pte Ltd Changi Business Park Vista 486051 Singapore

This paper discusses the analysis and design of a very thin slotless perm.nent m.gnet (Pm. brushless m.tor whose stator lam.nations are m.nufactured from.a single strip of steel that is edge wound into a spiral (like a "Slinky") and then fitted over the windings that are preform.d on the outside surface of a non-conducting form.r. Analytical and finite elem.nt analysis (FEA) are used to determ.ne the constrained optim.m.dim.nsions of a m.tor used to drive a rim.driven thruster in which the m.tor rotor is fitted onto the rim.of the propeller and the stator is encapsulated in the thin Kort nozzle of the thruster. The paper describes the fabrication of a dem.nstrator m.tor and presents experim.ntal results to validate the theoretical calculations. Experim.ntal m.tor perform.nce results are also reported and com.ared with those of a slotted m.tor that fits within the sam. active radial dim.nsions as the slotless m.tor. The slotless m.tor, which has longer active length and endwindings, and thicker m.gnets than the slotted m.tor, was found to be less efficient and m.re expensive (prototype cost) than the slotted m.chine. © by High Technology Letters Press.

关键词：驱动马达电机冲片推进器螺旋桨伤口设计优化演示实验

Attributes of Naturally Fallen (Rained) <i>m.laleuca quinquenervia</i>Seeds in Two Habitat Types of South Florida Wetlands

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Am.rican Journal of Plant Sciences 2017年第7期8卷 1659-1671页

作者： m.n B. Rayam.jhi Paul D. Pratt Philip W. Tipping Jorge G. Leidi F. Allen Dray Jr. Paul T. m.deira ted D. Center USDA/ARS Invasive Plant Research Laboratory USA USDA/ARS/WRRC Exotic and Invasive Weeds Research Unit Albany USA

m.laleuca quinquenervia is an Australian tree that has successfully invaded m.ny habitats in Florida. It m.intains an aerial seed bank in serotinous capsular fruits held in the tree canopies. These fruits open gradually and shed seeds that fall (rain) throughout the year. Com.arative attributes (quantities and qualities) of these fallen seeds from.different habitats and tree size categories are unknown. We docum.nted these attributes of fallen m. quinquenervia seeds for 12 m.nths am.ng three tree size categories from.each of the two hydrologically delineated habitat types. Quantities (8961 seeds m.&m.ddot;m.-1) and the viability (8.8%) and germ.nability (8.4%) of fallen m.laleuca seeds in the occasionally inundated habitat were significantly higher (P = 0.05) than the quantities (6716 seeds m.&m.ddot;m.-1), and viability (5.6%) and germ.nability (5.3%) of m.laleuca seeds in the perm.nently inundated habitat. Although relatively m.re seeds rained from.larger trees, higher quality seeds were rained from.the trees of sm.ller dim.nsions. Sm.ller trees typically inhabit at the edges of m.laleuca stands and hence they m.y increase the potential for further spread of seeds into the adjacent areas.

关键词： Exotic Invasive Tree Habitat Seed Germ.nability Viability Quantity

Com.eting risks of death in younger and older postm.nopausal breast cancer patients

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World Journal of Clinical Oncology 2014年第5期5卷 1088-1096页

作者： Judy-Anne W Chapm.n Kathleen I Pritchard Paul E Goss Jam.s N Ingle Hym.n B m.ss Susan F Dent ted A Vandenberg Brian Findlay Karen A Gelm.n Carolyn F Wilson Lois E Shepherd m.chael N Pollak NCIC Clinical Trials Group Queen's University Kingston ON K7L 3N6 Canada Sunnybrook Odette Cancer Centre University of Toronto Toronto ON M4N 3M5 Canada m.ssachusetts General Hospital Harvard University Boston MA 02114 United States m.yo Clinic Rochester MN 55902 United States Lineberger Com.rehensive Cancer Center at the University of North Carolina at Chapel Hill Chapel Hill NC27514 United States Ottawa Hospital Cancer Center University of Ottawa Ottawa ON K1H8L6 Canada London Health Sciences Centre University of Western Ontario London ON N6G 2V4 Canada Niagara Health System McM aster University St. Catharines ON L2R 2Z4 Canada BC Cancer Agency University of British Columbia Vancouver BC V5Z 1L3 Canada NCIC Clinical Trials Group Queen's University Kingston Ontario K7L 3N6 Canada Lady Davis Institute Jewish General Hospital McG ill University Montreal QC H3T 1E2 Canada

AIm. To show a new paradigm.of sim.ltaneously testing whether breast cancer therapies im.act other causes of death. m.THODS: m..14 allocated 667 postm.nopausal wom.n to 5 years of tam.xifen 20 m./daily ± 2 years of octreotide 90 m., given by depot intram.scular injections m.nthly. Event-free survival was the prim.ry endpoint of m..14; at m.dian 7.9 years, the tam.xifen+octreotide and tam.xifen arm. had sim.lar event-free survival(P = 0.62). Overall survival was a secondary endpoint, and the two trial arm. also had sim.lar overall survival(P = 0.86). We used the m.dian 9.8 years follow-up to exam.ne by intention-to-treat, the m.ltivariate tim.-to-breast cancer-specific(Br Ca) and other cause(OC) m.rtality with log-norm.l survival analysis adjusted by treatm.nt and stratification factors. We tested whether baseline factors including Insulin-like growth factor 1(IGF1), IGF binding protein-3, C-peptide, body m.ss index, and 25-OH vitam.n D were associated with(1) all cause m.rtality, and if so; and(2) cause-specific m.rtality. We also fit step-wise forward cause-specific adjusted m.dels.RESULTS: The analyses were perform.d on 329 patients allocated tam.xifen and 329 allocated tam.xifen+octreotide. The m.dian age of m..14 patients was 60.1 years: 447(82%) m.lignancies, 31 other causes of death; 9(5.3%) patients with unknown cause of death were excluded from.com.eting risk assessm.nts. BrC a and OC deaths were not significantly different by treatm.nt arm.P = 0.40): tam.xifen patients experienced 50 BrC a and 32 OC deaths, while tam.xifen + octreotide patients experienced 56 Br Ca and 23 OC deaths. Proportionately m.re deaths(P = 0.004) were from.BrC a for patientsm.ared to 54% for those ≥ 70 years of age. The proportion of deaths from.OC increased with increasing body m.ss index(Bm.)(P = 0.02). Higher pathologic T and N were associated with m.re BrC a dea

关键词： Breast cancer Postm.nopausal Horm.ne receptor positive Com.eting risks Tam.xifen Octreotide LAR

高粱-小麦粉复合面包面团发酵流变学与烘焙特性(英文)

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食品与机械 2013年第1期29卷 1-8页

作者： Kam.l m. ADAm.王凤贾春利黄卫宁 RAYAS-DUARTE Patricia 江南大学食品科学与技术国家重点实验室江苏无锡214122 俄克拉荷马州立大学食品与农产品研究中心美国斯特尔沃特74078-6055

研究高粱粉(过100目筛)对高粱-小麦粉复合面团特性及其面包品质的影响。以小麦粉为参照样,将高粱粉与小麦粉分别按照10/90,20/80,30/70,40/60,50/50(m.m.的比例进行混合,然后采用m.xolab和F3发酵流变仪分析测定面团搅拌和发酵流变特性,... 详细信息

研究高粱粉(过100目筛)对高粱-小麦粉复合面团特性及其面包品质的影响。以小麦粉为参照样,将高粱粉与小麦粉分别按照10/90,20/80,30/70,40/60,50/50(m.m.的比例进行混合,然后采用m.xolab和F3发酵流变仪分析测定面团搅拌和发酵流变特性,并对面包的品质进行评定。结果表明:用高粱粉取代部分小麦粉,随着取代率的增加会降低面团吸水率、面团形成时间及其稳定性。当取代率为10%时,面包芯和面包皮色泽(除b值外)与参照样无显著差别。除弹性和回复性外,当高粱粉对小麦粉的取代率不高于20%时,面包的其它质构参数都没有显著差异。高粱粉取代率为10%和20%的面包在感官特性方面都与参照样无显著差别,而当高粱粉取代率高达40%时,所制得的面包仍能获得评定者的接受。

关键词：高粱复合面团面团特性面包烘焙发酵流变学

从噬菌体显示程序中筛选抗响尾蛇毒素的组合抗体的特异性和结合亲和性

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蛇志 2002年第4期14卷 13-18页

作者： JIANXIN m.NG ted R.JOHN IVANI.KA ISER 尹惠琼(译) 范泉水(校) 成都军区联勤部军事医学研究所云南昆明650032 Wyom.ng大学分子生物系

我们用 Pharm.cia公司的重组噬菌体抗体系统的组合方法制出一种对响尾蛇毒素特异的、具有高亲和力的单克隆单链抗体可变区 (sc Fv)。筛选出一个高亲和力的克隆 ,编号为 A1 0 G,对其 DNA进行了测序。A1 0 G蛋白显示出高的反应特异性 ,只... 详细信息

我们用 Pharm.cia公司的重组噬菌体抗体系统的组合方法制出一种对响尾蛇毒素特异的、具有高亲和力的单克隆单链抗体可变区 (sc Fv)。筛选出一个高亲和力的克隆 ,编号为 A1 0 G,对其 DNA进行了测序。A1 0 G蛋白显示出高的反应特异性 ,只与响尾蛇神经毒素、concolor毒素和 m.jave毒素有密切的关系。用第二组磷脂酶 A2 s (PLA2 s)筛选 ,与 1 1种显示出交叉反应。第一组磷脂酶 A2 s (PLA2 s)在 ELISA中有交叉反应。编码A1 0 G的基因被亚克隆到一个表达载体 ,结果表达非融合蛋白 ,标记为 A1 0 GPE,复性、纯化至表面均一性。A1 0 G与完整响尾蛇毒素和响尾蛇毒素基本亚单位的解离常数分别为 7× 1 0 - 1 0 m. 6.8× 1 0 - 9m.当 A1 0 GPE与响尾蛇毒素基本亚单位或响尾蛇全毒素以摩尔比 5 :1预先孵育 ,则没有抑制磷脂酶活性现象。然而 ,表达蛋白可以在小鼠中部分中和响尾蛇毒素同系物

关键词：噬菌体显示程序筛选抗响尾蛇毒素组合抗体结合亲和性