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Standard-Cell Placement from Functional Descriptions

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Journal of Computer Science & Technology 1991年第1期6卷 37-46页

作者： klaus Buchenrieder Waldparkstraβe

This paper presents a functional language for the unambiguous description of digital circuits,a me- thod and algorithms to obtain a standard-cell layout,and a comparative evaluation of the developed func- tional standard-cell placement *** presented placement scheme is different from traditional methods because the complete layout geometry is specified and constructed automatically from a function- al *** construction relies on a translation that combines the simplicity of standard-cells with the elegance of functional *** evaluation of the method introduced shows that the quality of the resulting placement is close to the results achieved with simulated annealing while the computation time is significantly ***,the evaluation suggests to employ the functional placement me- thod in conjunction with low-temperature simulated annealing for running-time reduction and improved- results.

关键词： Standard-Cell Placement from Functional Descriptions

On combinatorial Gauss-Bonnet Theorem for general Euclidean simplicial complexes

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Frontiers of Mathematics in China 2016年第5期11卷 1345-1362页

作者： Stephan klaus Scientific Administrator of the MFO and Adjunct Professor at Mainz University Mathematisches Forschungsinstitut Oberwolfach gGmbH (MFO) Schwarzwaldstrasse 9-11 D-77709 Oberwolfach-Walke Germany

For a finitely triangulated closed surface M2, let αx be the sum of angles at a vertex x. By the well-known combinatorial version of the 2- dimensional Gauss-Bonnet Theorem, it holds ∑x（2π- αx） =2αχ（M^2）, where X denotes the Euler characteristic of M^2, αx denotes the sum of angles at the vertex x, and the sum is over all vertices of the triangulation. We give here an elementary proof of a straightforward higher-dimensional generalization to Euclidean simplicial complexes K without assuming any combinatorial manifold condition. First, we recall some facts on simplicial complexes, the Euler characteristics and its local version at a vertex. Then we define δ（τ） as the normed dihedral angle defect around a simplex τ. Our main result is ∑τ（-1）^dim（τ）δ（τ） = χ（K）, where the sum is over all simplices τ of the triangulation. Then we give a definition of curvature k（x） at a vertex and we prove the vertex-version ∑x∈K0 k（x） = χ（K） of this result. It also possible to prove Morse-type inequalities. Moreover, we can apply this result to combinatorial （n ＋ 1）-manifolds W with boundary B, where we prove that the difference of Euler characteristics is given by the sum of curvatures over the interior of W plus a contribution from the normal curvature along the boundary B： χ（W）- 1/2 χ（B） = ∑τ∈W-B（-1）^dim（τ）δ（τ）＋ ∑τB（-1）^dim（τ）ρ（τ）.

关键词： Curvature dihedral angle Euclidean simplex triangulation Euler characteristic Euler manifold combinatorial manifold pseudo manifold

Natural water purification and water management by artificial groundwater recharge

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第3期9卷 221-226页

作者： klaus-Dieter BALKE Institute for Geosciences University of TübingenSigwartstr.10D-72076 TübingenGermany

Worldwide,several regions suffer from water scarcity and *** infiltration and subsurface storage of rain and river water can reduce water *** groundwater recharge,possibly combined with bank filtration,plant purification and/or the use of subsurface dams and artificial aquifers,is especially advantageous in areas where layers of gravel and sand exist below the earth's *** infiltration of surface water into the uppermost aquifer has qualitative and quantitative *** contamination of infiltrated river water will be reduced by natural *** minerals,iron hydroxide and humic matter as well as microorganisms located in the subsurface have high decontamination *** this,a final water treatment,if necessary,becomes much easier and *** quantitative effect concerns the seasonally changing river discharge that influences the possibility of water extraction for drinking water *** changes can be equalised by seasonally adapted infiltration/extraction of water in/out of the aquifer according to the river discharge and the water *** method enables a continuous water supply over the whole ***,artificially recharged groundwater is better protected against pollution than surface water,and the delimitation of water protection zones makes it even more save.

关键词： Artificial groundwater recharge Natural attenuation Water management

Recent results on hadron spectroscopy from BES

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Chinese Physics C 2010年第6期34卷 638-643页

作者： klaus Gtzen GSI Helmholtzzentrum für Schwerionenforschung GmbH

The BES-Ⅲ Detector is a very versatile multipurpose device located at the Institute of High Energy Physics （IHEP） in Beijing, China. Concerning the physics program it ties stringently up to the past BES and BES-Ⅱ experiments. Since start of the data taking in the middle of 2008 the accumulated dataset of 200.10^6 J/ψ events and 100.10^6 ψ＇ events already exceeds the world data on these resonances. In addition to studies of the charmonium systems the data offers great opportunity for investigations in the light hadron sector. In detail it will be reported about the confirmation of the enhancement in pp invariant mass in radiative J/ψ decays, the search for decays Y（2175） → K＊0K＊0, observation of a charged K^± in K^±π^0 and observation of a new excited baryon N＊（2065） decaying to pπ^0 and charged onjugate. The first result is based on data taken by BES-Ⅱ and BES-Ⅲ, the latter three on data collected by BES-Ⅱ only.

关键词： light hadrons BES X(1860) Y(2175) k^+ N*(2065)

Heat stress in pigs and broilers:role of gut dysbiosis in the impairment of the gut-liver axis and restoration of these effects by probiotics,prebiotics and synbiotics

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Journal of Animal Science and Biotechnology 2023年第2期14卷 465-480页

作者： Robert Ringseis klaus Eder Institute of Animal Nutrition and Nutrition Physiology Justus-Liebig-University GiessenHeinrich‑Buff‑Ring 26‑3235392 GiessenGermany

Heat stress is one of the most challenging stressors for animal production due to high economic losses resulting from impaired animal’s productivity,health and *** the fact that all farm animal species are susceptible to heat stress,birds and pigs are particularly sensitive to heat stress due to either lacking or non-functional sweat ***-vincing evidence in the literature exists that gut dysbiosis,a term used to describe a perturbation of commensal gut microbiota,develops in broilers and pigs under heat *** to the protective role of commensal bacteria for the gut barrier,gut dysbiosis causes a disruption of the gut barrier leading to endotoxemia,which contributes to the typical characteristics of heat stressed broilers and growing and growing-finishing pigs,such as reduced feed intake,decreased growth and reduced lean carcass weight.A substantial number of studies have shown that feeding of probiotics,prebiotics and synbiotics is an efficacious strategy to protect broilers from heat stress-induced gut barrier disruption through altering the gut microbiota and promoting all decisive structural,biochemical,and immunologi-cal elements of the intestinal *** most of the available studies in heat stressed broilers,the alterations of gut microbiota and improvements of gut barrier function induced by feeding of either probiotics,prebiotics or synbiot-ics were accompanied by an improved productivity,health and/or welfare when compared to non-supplemented broilers exposed to heat *** findings indicate that the restoration of gut homeostasis and function is a key target for dietary interventions aiming to provide at least partial protection of broilers from the detrimental impact of heat stress *** the fact that the number of studies dealing with the same feeding strategy in heat stressed pigs is limited,the available few studies suggest that feeding of probiotics might also be a suitable approach to enhance productivi

关键词： Broilers Commensal bacteria Gut dysbiosis Heat stress Pigs Prebiotics Probiotics Synbiotics

Direct oral anticoagulants: a new therapy against Alzheimer's disease?

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Neural Regeneration Research 2021年第8期16卷 1556-1557页

作者： klaus Grossmann Center for Plant Molecular Biology(ZMBP) University of TübingenTübingenGermany

More than 40 million people worldwide are thought to be affected by Alzheimer's disease(AD).Of these,estimated less than10% develop symptoms usually well before the age of 65,due to familial(hereditary) AD predisposition(Sierksma et al.,2020).AD is a multifactorial disorder,which includes a multitude of progressive degenerations in the brain parenchyma,but also in the vascular and hemostatic system.

关键词： Alzheimer degeneration al.

Semaphorins or Frizzled–it is the receptor that direct the action of clostridial glucosylating toxins

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Signal Transduction and Targeted Therapy 2020年第1期5卷 772-773页

作者： klaus Aktories Institute of Experimental and Clinical Pharmacology and Toxicology Medical FacultyUniversity of FreiburgAlbertstr.2579104 FreiburgGermany

In a recent article in Cell,Lee et al.1 establish semaphorins SEMA6A and SEMA6B as physiologically relevant receptors for Paeniclostridium sordellii lethal toxin(TcsL)which can cause lethal toxic shock syndrome and reveal the molecular basis for the difference in tissue targeting and disease pathogenesis between highly related toxins TcsL and *** TcdB.

关键词： al pathogenesis action

A characterization of finite simple groups by the orders of solvable subgroups

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Science China Mathematics 2007年第5期50卷 715-726页

作者： klaus DENECKE Institut für Mathematik Universitt PotsdamGermany

Let G be a finite group and S be a finite simple group. In this paper, we prove that if G and S have the same sets of all orders of solvable subgroups, then G is isomorphic to S, or G and S are isomorphic to Bn(q), Cn... 详细信息

关键词： finite simple groups solvable subgroup order characterization 20D08 20D05

Testing and modelling of transient adhesion phenomena in rolling-sliding contacts

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Friction 2024年第5期12卷 1016-1027页

作者： Daniel KVARDA Alexander MEIERHOFER klaus SIX Faculty of Mechanical Engineering Brno University of TechnologyBrno61669Czech Republic Virtual Vehicle Research GmbH Graz8010Austria

Transient adhesion effects in rolling–sliding contacts influence all aspects of train–track *** is of high importance specifically when these effects result in critically low adhesion,which poses a risk to traction and braking of railway *** study presents a model that can replicate the transient changes of the coefficient of adhesion with tested water and solid particle *** experimental data for the model are measured using a commercial ball-on-disc *** experimental results showed a liquid reservoir in front of the contact area that slowly reduces in *** observation was used in the modelling approach to divide the calculation into two stages where the reservoir is present and when it *** model was able to reproduce the occurrence of low adhesion region seen in experimental results with different particle concentrations.

关键词： coefficient of adhesion tribology transient effects wheel-rail contact