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Psychiatric comorbidities in cancer survivors across tumor subtypes:A systematic review

World Journal of Psychiatry 2022年第4期12卷 623-635页

作者： Anne Bach klara knauer Johanna Graf Norbert Schäffeler Andreas Stengel Section Psychooncology Department of Psychosomatic Medicine and PsychotherapyUniversity Hospital TübingenTübingen 72076Germany Germany&CharitéCenter for Internal Medicine and Dermatology Department for Psychosomatic MedicineCharite-Universitätsmedizin BerlinCorporate Member of Freie Universität BerlinHumboldt-Universität zu Berlin and Berlin Institute of HealthBerlin 10117Germany

BACKGROUND Psychiatric disorders are common but underdiagnosed in cancer *** suggests that tumor type has an effect on the prevalence of clinically relevant depression,anxiety,comorbid anxiety-depression and posttraumatic stress disorder(PTSD).AIM To identify studies that examined the prevalence of clinically relevant levels of depression,anxiety,comorbid anxiety-depression and PTSD for patients with one or more tumor sites and compare those prevalences between cancer *** Four databases(PubMed,PsycInfo,PubPsych and the Cochrane Database)were searched and resulted in a total of 2387 articles to be *** be included,a study must have investigated cancer-free and posttreatment survivors using tools to assess clinically relevant levels of the listed psychiatric *** articles were screened by two authors with a third author reviewing debated *** Twenty-six studies on ten different tumor types fulfilled all inclusion criteria and were included in the *** studies showed heterogeneity regarding the study characteristics,number of participants,time since diagnosis,and assessment ***,all four comorbidities show higher prevalences in cancer survivors than the general *** tumor survivors were reported to have a relatively high prevalence of both depression and *** with melanoma survivors reported high prevalences of all four psychiatric *** comorbidities,a wide range in prevalence existed across the tumor *** one cancer site,the prevalence also varied considerably among the *** Psychiatric comorbidities are more frequent in cancer survivors than in the general population,as reflected by the prevalence of depression,anxiety,comorbid anxiety-depression and PTSD across all tumor *** generalized screening tools that examine psychological distress in cancer survivors up to at least ten years after diagnosis could help to

关键词： Cancer survivor Cancer type Prevalence Psychiatric disorder Psychiatric comorbidity Survivorship Tumor site

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