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Cytomegalovirus-associated gastric ulcer:A side effect of steroid injections for pyloric stenosis

World Journal of Gastroenterology 2013年第7期19卷 1143-1146页

作者： Hirohito Mori Shintaro Fujihara Noriko Nishiyama Hideki Kobara Makoto Oryu kiyohito kato Kazi Rafiq Tsutomu Masaki Departments of Gastroenterology and Neurology Kagawa Medical University School of MedicineKagawa 761-0793Japan Departments of Pharmacology Kagawa Medical University School of MedicineKagawa 761-0793Japan

The local injection of triamcinolone acetonide(TA) is effective in preventing pyloric stenosis and deformity following large endoscopic submucosal dissection(ESD).However,because of its long-acting nature,TA can induce long-term local immunosuppression and subsequent adverse *** report a case of a cytomegalovirus(CMV) ulcer that formed only at the TA local injection site.A 68-year-old man underwent ESD to treat early gastric cancer that formed over the *** lesion extended to the duodenum,and an artificial ulcer covered more than two-thirds of the circumference of the *** prevent pyloric stenosis,TA was locally injected into the ulcer *** day 12,a deeper ulcer 10 mm in diameter was discovered in the center of the post-ESD *** revealed large cells with intranuclear inclusion bodies,which stained positive for the anti-CMV *** TA injections are useful,however,CMV ulcer might occur as adverse events.

关键词： Pyloric stenosis Local triamcinolone acetonide injection Local immunosuppression Cytomegalovirus-associated ulcer Adverse events

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Radical excision of Barrett's esophagus and complete recovery of normal squamous epithelium

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World Journal of Gastroenterology 2013年第31期19卷 5195-5198页

作者： Hirohito Mori Hideki Kobara Kazi Rafiq Noriko Nishiyama Shintaro Fujihara Maki Ayagi Tatsuo Yachida kiyohito kato Tsutomu Masaki Department of Gastroenterology and Neurology Kagawa University Kagawa 761-0793 Japan Department of Pharmacology Kagawa UniversityKagawa 761-0793 Japan

To treat Barrett's esophagus(BE),radiofrequency ablation or cryotherapy are effective treatments for eradicating BE with dysplasia and intestinal metaplasia,and reduce the rates of Barrett's esophageal adenocarcinoma(BAC).However,patients with BE and dysplasia or early cancer who achieved complete eradication of intestinal metaplasia,BE recurred in 5% within a year,requiring expensive endoscopic *** performed endoscopic submucosal dissection as complete radically curable treatment procedure for BE with dysplasia,intestinal metaplasia and BAC.

关键词： Barrett’s esophagus Radiofrequency ablation Cryotherapy Endoscopic submucosal dissection Radically curable treatment

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