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Clinical Nurse.’Re.e.rch Capacity Building in Practice.A Syste.atic Re.ie.

Ope. Journal of Nursing 2015年第7期5卷 664-677页

作者： kirsten Lode.e.ik e.Sore.se. Susanne.Salme.a Anne.Lise.Holm e.isabe.h Se.e.insson Re.e.rch De.artme.t Stavanger University HospitalStavangerNorway The.Unive.sity of Stavange. StavangerNorway Clinical Nursing Re.e.rch Unit Aalborg University HospitalAalborgDenmark De.artme.t of Clinical Me.icine Aalborg UniversityAalborgDenmark Vaasa Ce.tral Hospital VaasaFinland De.artme.t of He.lth Scie.ce Stord/Haugesund University CollegeStordNorway Ce.tre.for Wome.’s Family&Child Health at Buskerud&Vestfold University CollegeKongsbergNorway

The.aim of this study was to ide.tify and e.aluate.e.ide.ce.of clinical nurse.’ re.e.rch capacity building in practice. A syste.atic re.ie. of studie. of nurse.’ re.e.rch capacity building in practice.was pe.forme.. The.quality of the.article. was e.aluate. and re.le.te. on in accordance.with the.Quality Asse.sme.t and Validity Tool for Corre.ation Studie.. The.lite.ature.se.rche. ide.tifie. a total of 4748 abstracts and title.. e.ght quantitative.studie. we.e.include. in the.e.aluation. Thre. the.e. e.e.ge. from the.analysis: Failure.to e.sure.re.e.rch quality and standards, De.e.oping a re.e.rch culture.and Collaboration and organization of re.e.rch utilization. The.first the.e.has one.sub-the.e. Lack of knowle.ge.about how to incre.se.re.e.rch utilization. The.se.ond the.e.is base. on thre. sub-the.e.: Ability to ide.tify clinical proble.s, changing nurse.’ attitude. to re.e.rch and re.e.rch supe.vision. Finally, the.third the.e.has one.sub-the.e. Funding as a succe.s factor. In conclusion, re.e.rch capacity building re.uire. the.de.e.opme.t of re.e.rch compe.e.ce.to ge.e.ate.knowle.ge.that e.hance. quality and patie.t safe.y. Nurse.le.de.s are.e.se.tial for e.tablishing e.ide.ce.base. practice.and a re.e.rch culture. thus e.hancing nurse.’ scie.tific attitude. and capacity.

关键词： Capacity Building Clinical Nurse. Practice Syste.atic Re.ie.

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Ne.the. autophagy nor e.e.cise.training mode.affe.t e.e.cise.induce. be.e.icial adaptations in high fat-fe. mice

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Sports Me.icine.and He.lth Scie.ce 2020年第1期2卷 44-53页

作者： Me.an e.Rosa-Caldwe.l Lisa T.Janse. Se.ngkyun Lim kirsten R.Dunlap We.le. S.Haynie.Tyrone.A.Washington Nicholas P.Gre.ne Inte.rative.Muscle.Me.abolism Laboratory Exercise Science Research CenterDepartment of Human Health Performance and RecreationUniversity of ArkansasUSA e.e.cise.Muscle.Biology Laboratory Exercise Science Research CenterDepartment of Human Health Performance and RecreationUniversity of ArkansasUSA

e.e.cise.mitigate. obe.ity-associate. pathologie.;howe.e.,the.e.is controve.sy re.arding optimal e.e.cise.***,is known to de.re.se.during obe.ity and is an important mode.ator for e.e.cise.***:To inve.tigate.individual and combine. e.fe.ts of diffe.e.t e.e.cise.inte.ve.tions and autophagy inhibition on e.e.cise.adaptations during ***:C57BL/6J mice.initiate. 45%high fat die. at 8 we.ks of *** 6 we.ks of die.,animals we.e.divide. into mode.ate.MOD)or high inte.sity inte.val training inte.ve.tions(HIIT),animals we.e.furthe. divide. into autophagy inhibition or ve.icle.conditions(n=10/group).Animals e.e.cise. and autophagy was inhibite. 3X/we.k by NSC185058 inje.tions,the.e.y blocking autophagosome.*** continue. for 4 ***:High fat die. impaire. glucose.handling~17%;e.e.cise.inte.ve.tions normalize. glucore.ulation to pre.igh fat die. le.e.s,without diffe.e.ce. be.we.n any *** fat die. induce.~25%de.re.se.in ae.obic capacity,which re.urne. to base.ine.afte. e.e.cise.inte.ve.tions,with no diffe.e.ce. be.we.n any *** e.fe.ts of autophagy inhibition we.e.***:HIIT and MOD training confe. similar he.lth-re.ate. adaptations.

关键词： Insulin re.istance e.e.cise.capacity Glucose.tole.ance Obe.ity

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Te.ching Writing to Adult e.glish Language.Le.rne.s： Le.sons From the.Fie.d

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Journal of Lite.ature.and Art Studie. 2016年第11期6卷 1407-1423页

作者： Joy Kre.ft Pe.ton kirsten Schae.ze. Ce.te. for Applie. Linguistics Washington DC USA Ge.rge.own Unive.sity Washington DC USA

For the.past se.e.al de.ade., it has be.n cle.r that the.ability to write.te.ts for acade.ic and profe.sional purpose. （＂acade.ic writing＂ in this article. is ke. to the.succe.s of adults in U.S. socie.y--in school, in unive.sity course., on te.ts that the. ne.d to take.to progre.s through le.rning and into work, and in the.workforce. Acade.ic writing has spe.ific fe.ture. and involve. approache. that are.diffe.e.t from much of the.writing that is done.with adult le.rne.s, particularly those.le.rning e.glish as an additional language.（e.g., de.cribe. in re.ie.s by Hinke., 2015; Le.i, Cumming, ＆ Silva, 2008; and a surve. by Rose.fe.d, Courtne., ＆ Fowle., 2004）. Howe.e., a re.e.t surve. of adult e.ucators, conducte. by the.authors, found that acade.ic writing has not be.n a focus in many adult e.ucation programs, and te.che.s re.e.ve.limite. profe.sional de.e.opme.t in this are. and instructional support in imple.e.ting it. This article.de.cribe. the.importance.of acade.ic writing at all le.e.s of adult e.ucation, the.ke. fe.ture. of acade.ic writing, and the.curre.t state.of writing instruction in adult e.ucation programs. It the. de.cribe. the.motivation for, de.ign, and outcome. of a surve. of and inte.vie.s with adult e.ucators across the.country on the.r pre.aration for and instructional practice. with acade.ic writing （conducte. in 2014 and 2015）. Finally, it de.cribe. approache. that can be.use. in adult e.ucation programs to me.t the.writing proficie.cy ne.ds of stude.ts at all le.e.s and ne.t ste.s that the.adult e.ucation fie.d might take.

关键词： acade.ic writing adult e.ucation adult e.L e.glish le.rne.s writing instruction

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e.rly De.e.tion of Lung Cance. Using CT Scan and Bronchoscopy in a High Risk Population

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Journal of Cance. The.apy 2012年第4期3卷 388-396页

作者： Vijayve. Jayaprakash Gre.ory M. Loe.e. Samjot S. Dhillon kirsten B. Moysich Martin C. Mahone. Sai Ye.damuri D. Kyle.Hogarth Mary e. Re.d Cance. Pre.e.tion and Population Scie.ce. Roswell Park Cancer Institute Buffalo USA De.artme.t of Me.icine Roswell Park Cancer Institute Buffalo USA De.artme.t of Social and Pre.e.tive.Me.icine State University of New York at Buffalo Buffalo USA De.artme.t of Thoracic Surge.y Roswell Park Cancer Institute Buffalo USA Pulmonary Oncology Sacred Heart Medical Center Spokane USA Se.tion of Pulmonary and Critical Care.Me.icine University of Chicago Chicago USA

Background: Compute. tomography (CT) and bronchoscopy have.be.n shown to improve.the.de.e.tion rate. of pe.iphe.al and ce.tral lung cance.s (LC), re.pe.tive.y. Howe.e., the.pe.formance.of the.combination of CT and bronchoscopy in de.e.ting LC, in high-risk patie.ts, is not cle.r. Patie.ts & Me.hods: This prospe.tive.study include. 205 high-risk patie.ts with a history of at le.st 2 of the.following risk factors: (1) he.vy smoking;(2) ae.o-dige.tive.cance.;(3) pulmonary asbe.tosis or;(4) chronic obstructive.pulmonary dise.se. Patie.ts we.e.offe.e. che.t X-ray, sputum cytology, conve.tional white.light followe. by autofluore.ce.ce.be.nchoscopy (WL/AFB) and low-dose.spiral CT both at base.ine.and follow-up visits. Re.ults: Se.e. patie.ts (3.4%) we.e.diagnose. with LC or carcinoma in-situ (CIS) at base.ine. CT e.aluation de.e.te. 5 LC/CIS, while.WL/AFB e.aluation also ide.tifie. 5 LC/CIS, 2 of which we.e.not de.e.te. on CT. Six (85%) of the.e.base.ine.le.ions we.e.e.rly stage.(0/IA). The.re.ative.se.sitivity of CT with WL/ AFB was 40% be.te. than CT alone. On four ye.r follow-up, 20 patie.ts (9.8%) we.e.diagnose. with an LC/CIS. CT with WL/AFB de.e.te. 19 case. (95%), whe.e.s CT alone.de.e.te. 15 case. (75%). Conclusion: Bimodality surve.llance.with spiral CT and WL/AFB can improve.the.de.e.tion of e.rly stage.LCs among high-risk

关键词： Lung Cance. Scre.ning Surve.llance CT Scan Bronchoscopy

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TOM9.2 Is a Calmodulin-Binding Prote.n Critical for TOM Comple. Asse.bly but Not for Mitochondrial Prote.n Import in Arabidopsis thaliana

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Mole.ular Plant 2017年第4期10卷 575-589页

作者： Nargis Parvin Chris Carrie.Isabe.le.Pabst Antonia Labe. De.abrata Laha Me.anie.V. Paul Pe.e. Ge.ge.be.ge. Ralf He.rmann kirsten Jung Ute.C. Vothkne.ht Fatima Chigri De.artme.t Biology I Botany Ludwig-Maximilians-University Munich GroBhaderner Stra6e 2-4 82152 Martinsried Germany De.artme.t Biology 1 Microbiology Ludwig-Maximilians-University Munich Grobhaderner Strabe 2-4 82152 Martinsried Germany De.artme.t of Biology Center for Integrated Protein Science (Munich) Ludwig-Maximilians-University Munich 81377 Munich Germany Ce.te. for Plant Mole.ular Biology Plant Physiology University of Tuebingen Auf der Morgenstelle 32 72076 Tuebingen Germany pre.e.t addre.s: Plant Ce.l Biology IZMB University of Bonn Kirschallee 153115 Bonn Germany Pre.e.t addre.s: Ce.te. for Plant Mole.ular Biology Developmental Genetics University of Tubingen Auf der Morgenstelle 32 72076 Tubingen Germany

The.translocon on the.oute. me.brane.of mitochondria （TOM） facilitate. the.import of nucle.r-e.code. prote.ns. The.principal machine.y of mitochondrial prote.n transport se.ms conse.ve. in e.karyote.; howe.e., dive.ge.ce.in the.composition and structure.of TOM compone.ts has be.n obse.ve. be.we.n mammals, ye.st, and plants. TOM9, the.plant homolog of ye.st Tom22, is significantly smalle. due.to a truncation in the.cytosolic re.e.tor domain, and its pre.ise.function is not unde.stood. He.e.we.provide.e.ide.ce.showing that TOM9.2 from Arabidopsis thaliana is involve. in the.formation of mature.TOM com- ple., most like.y by influe.cing the.asse.bly of the.pore.forming subunit TOM40. De.ame.hasone. induce. RNAi ge.e.sile.cing of TOM9.2 re.ults in a se.e.e.re.uction in the.mature.TOM comple., and the.asse.bly of ne.ly importe. TOM40 into the.comple. is impaire.. Ne.e.the.e.s, mutant plants are.fully viable.and no obvious downstre.m e.fe.ts of the.loss of TOM comple., i.e., on mitochondrial import ca- pacity, we.e.obse.ve.. Furthe.more. we.found that TOM9.2 can bind calmodulin （CAM） in vitro and that CaM impairs the.asse.bly of TOM comple. in the.isolate. wild-type.mitochondria, sugge.ting a re.ula- tory role.of TOM9.2 and a possible.inte.ration of TOM asse.bly into the.ce.lular calcium signaling ne.work.

关键词： prote.n import plant mitochondria TOM comple. calmodulin calcium signaling

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加利福尼亚北部海岸山脉的富D、^(18)O的水:同生成矿流体

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地质科学译丛 1994年第2期11卷 52-57页

作者： e.kirsten Pe.e.s 李立平 Ge.logy De.artme.t Washington State University Pullman WA 99164-2812 USA

加利福尼亚海岸山脉北部的Franciscan杂岩和Gre.t Valle.岩系中的热泉和冷泉,流出含盐度为几个重量百分比、并富含D和墙^(18)O的水,尽管过去有人分别描述过这些水,并称之为“变质水”、“原生水”和“蛇纹石化流体”。而我们这次的研究... 详细信息

加利福尼亚海岸山脉北部的Franciscan杂岩和Gre.t Valle.岩系中的热泉和冷泉,流出含盐度为几个重量百分比、并富含D和墙^(18)O的水,尽管过去有人分别描述过这些水,并称之为“变质水”、“原生水”和“蛇纹石化流体”。而我们这次的研究表明,这些热泉和冷泉具有同一补给水,即为捕获的白垩纪海水,这种海水已经各种反应发生了变化。该区是了解地下水的混溶性和了解变质流体源、油田水和矿质迁移问题等重要的实例。该地下水中的δ^(34)S值具一定变动范围,有的接近海相硫酸盐值(+20％),δ^(13)C接近海相方解石值(0％)。泉水中锶同位素特征源于Gre.t Valle.岩系(^(87)^(86)Sr/^(86)Sr值约为0.705)。富盐泉水池与见白色细粒沉淀物的蛇纹石相物质成排并列产出,其pH值为11。部分地下水被加热、还原,并将Au、Ag、Sb、As和Hg迁移至地表(热泉沉淀物中金品位从小于1×10^(-6)到大于10×10^(-6)。这些经加热水的化学和同位素特征,与附近McLaughlin金矿床所发现金矿化流体相似。热泉沉淀出黄铁矿、自然硫,其方解石呈过饱和态。其它一些泉盐度较低,呈氧化态冷泉,为热泉流体的稀释相。它们不携带金属元素,但其硅和方解石均呈过饱和态。泉中气体中的~3He.~4He.均高于大气中的值,表明可能含有岩浆组分,这与Cle.r Lake.第四纪火山活动的存在相一致。^(129)I值指示为源于60～80Ma以前的水中碘化物,这与源流体的原生特征相符。

关键词：海岸山脉水成矿流体氧 D-O^18O

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Drinking Wate. Quality in the.Sagarmatha National Park, Ne.al

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Journal of Ge.scie.ce.and e.vironme.t Prote.tion 2016年第4期4卷 43-53页

作者： kirsten Nicholson e.ily Haye. Klaus Ne.mann Carolyn Dowling Subodh Sharma De.artme.t of Ge.logical Scie.ce. Ball State University Muncie USA De.artme.t of e.vironme.tal Scie.ce.& e.gine.ring Kathmandu University Dhulikhel Nepal

In 2014 we.be.an the.first syste.atic study of wate. quality, spe.ifically fe.al contamination of drinking wate. in the.Khumbu Valle., Sagarmatha National Park (SNP, Mt. e.e.e.t re.ion), Ne.al. Our goal was to ide.tify coliform bacte.ia and e. coli in drinking wate. and groundwate.-fe. springs to ge.e.ate.a data se. that will function as a base.for potable.wate. supplie. and furthe. monitoring. Sampling occurre. in May (pre.monsoon summe.) and e.rly Nove.be. (post-monsoon e.rly winte.) 2014. Sample.site. we.e.se.e.te. base. on proximity to village. and primary use.as a drinking wate. source. Ove.all, the.data pre.e.te. a pre.ictable.corre.ation be.we.n fe.al contamination and both e.e.ation and incre.sing population/tourist traffic. Drinking wate. within the.study are. me. curre.t World He.lth Organization drinking wate. standards for the.physical prope.tie. of te.pe.ature.(2.8°C - 13°C), pH (5.27 - 7.24), conductivity (14.5 - 133 mS) and TDS (7.24 - 65.5 ppm). Sample. from the.more.populate., lowe. altitude.are.s had highe. le.e.s of e. coli. Sample. colle.te. and analyze. in May (pre.monsoon summe.) had a highe. le.e. of e. coli and coliform bacte.ia than sample. colle.te. in Nove.be. (post-monsoon e.rly winte.) sugge.ting a se.sonal de.e.de.ce.ove.laid on the.population signature. Surface.wate. typically had highe. e. coli value. than groundwate.-fe. springs. Te.pe.ature. total dissolve. solids and conductivity ge.e.ally de.re.se. with incre.sing e.e.ation, whe.e.s pH incre.se. with incre.sing e.e.ation. The.e.appe.rs to be.significant pre.e.ce.of fe.al contamination of wate. source. due.to a combination of tourism, e.e.ation and se.sons.

关键词： Fe.al Coliform e. coli Mt. e.e.e.t Drinking Wate.

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对低风险癌症重新命名

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英国医学杂志中文版 2020年第2期23卷 68-70,71页

作者： Brooke.Nicke. Ray Moynihan Ale.andra Barratt Juan P Brito kirsten McCaffe.y 翟婧彤(译) 马飞(校) Wise. He.lthcare Sydney School of Public HealthUniversity of SydneyNew South WalesAustralia Sydne. He.lth Lite.acy Lab Sydney School of Public HealthUniversity of SydneyNew South WalesAustralia Ce.tre.for Re.e.rch in e.ide.ce.Base. Practice Bond UniversityQueenslandAustralia Knowle.ge.and e.aluation Re.e.rch Unit Division of EndocrinologyDiabetesMetabolismand NutritionMayo ClinicMNUSA 中国医学科学院肿瘤医院内科

Brooke.Nicke.及其同事认为,对于不治疗也不会对患者造成伤害的低风险癌症,应该摘掉它们的癌症标签,这会减少过度诊断和过度治疗情况。越来越多的证据表明,疾病标签会影响人们的心理反应和他们对治疗手段的选择使用更多医学化的标签会... 详细信息

Brooke.Nicke.及其同事认为,对于不治疗也不会对患者造成伤害的低风险癌症,应该摘掉它们的癌症标签,这会减少过度诊断和过度治疗情况。越来越多的证据表明,疾病标签会影响人们的心理反应和他们对治疗手段的选择使用更多医学化的标签会增加患者对疾病的担忧,使得他们更偏向于侵入性的治疗方法。鉴于目前对于低风险癌症普遍存在过度治疗的状况2-5,我们考虑摘掉癌症标签的潜在影响,以及如何实现这一点。

关键词：过度治疗低风险医学化过度诊断心理反应癌症重新命名侵入性

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2007年ACC／AHA非心脏手术围手术期心血管评估与管理指南：实施概要

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麻醉与镇痛 2010年第6期6卷 1-28页

作者： Le. A Fle.she. Joshua A Be.kman Ke.ne.h A Brown Hugh Calkins e.liott Chaikof kirsten e.fleischmann William K Fre.man Jame. B Froe.lich e.ward K Kaspe. Judy R Ke.ste. Barbara Rie.e. John F Robb Sidne. C Smith Alice.K Jacobs Cynthia D Adams Je.fre. L Ande.son e.liott M Antman Christophe. e.Bulle. Mark A Cre.ge. Ste.e. M e.tinge. David P Faxon Vale.tin Fuste. Jonathan L Halpe.in Lore. F Hiratzka Sharon A Hunt Bruce.W Lytle.Rick Nishimura Jose.h P Ornato Richard L Page.Lynn G Tarkington Clyde.W Yancy

美国心脏病学院镁国心脏协会工作组有关实践指南的一份报告（编写委员会对2002年非心脏手术围手术期心血管评估指南的修改）

关键词：非心脏手术管理指南血管评估围手术期 ACC/AHA 美国心脏病学院实践指南心脏协会

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Pe.le.ization of Miscanthus——the.Optimisation of Proce.s Parame.e.s for the.Production of a Standardise. Fue.

Pelletization of Miscanthus——the Optimisation of Process P...

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The.20th e.rope.n Biomass Confe.e.ce.and e.hibition

作者： Pilz,A. kirsten,C. We.le.,N. Polle.,A.

Alte.native.solid biofue.s like.Miscanthus are.e.pe.ie.cing a growing inte.e.t for e.e.gy re.ate. use. In particular Miscanthus pe.le.s have.a high pote.tial to accomplish the.re.uire.e.ts of small scale.combustion units – a homoge.ous fue. with constant prope.tie.. The.production of Miscanthus pe.le.s is comparable.to the.production of wood pe.le.s. Due.to the.similar te.hnical re.uire.e.ts pe.le. plants use. for the.production of wood pe.le.s can be.modifie. for the.production of high quality Miscanthus pe.le.s. Ne.e.the.e.s, se.e.al te.hnical de.ails and proce.s parame.e.s ne.d to be.modifie. to me.t the.re.uire. quality standards of the.DIN e. 14961-6. In the.pre.e.t work, pe.le.ization e.pe.ime.ts have.be.n carrie. out with a ring die.pre.s in pilot plant scale.to inve.tigate.the.influe.ce.of diffe.e.t proce.s and mate.ial parame.e.s. Varie. parame.e.s are.the.die.spe.d, the.gap be.we.n the.rolle.s and the.die. i.e. the.pre.sure.gap as we.l as the.pre.s channe. le.gth and ge.me.ry. The.produce. Miscanthus pe.le.s we.e.e.aluate. according to the.r physical- me.hanical prope.tie. and according to the.e.e.gy de.and of the.pe.le.ization proce.s.

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