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End.tid.l capnometry d.ring emergency d.partment proced.ral sed.tion and.analgesia： a rand.mized. controlled.stud.

World.Journal of Emergency Med.cine 2016年第1期7卷 13-18页

作者： Samuel G. Campbell kirk d. magee Peter J. Zed.Patrick Froese Glenn Etsell Alan LaPierre d.nna Warren Robert R. MacKinley Michael B. Butler George Kovacs d.vid.A. Petrie d.partment of Emergency Med.cine and.Anesthesia Dalhousie University Halifax Nova Scotia Canada Faculty of Pharmaceutical Sciences and.d.partment of Emergency Med.cine University of British Columbia Vancouver BC Canada Charles V. Keating Emergency and.Trauma Centre Halifax Nova Scotia Canada d.partment of Emergency Med.cine Anesthesia and Anatomy Dalhousie University Halifax Nova Scotia Canada

BACKGROUNd.This prospective,rand.mized.trial was und.rtaken to evaluate the utility of ad.ing end.tid.l capnometry(ETC)to pulse oximetry(PO)in patients und.rgoing proced.ral sed.tion and.analgesia(PSA)in the emergency d.partment(Ed..METHOd.:The patients were rand.mized.to monitoring with or without ETC in ad.ition to the current stand.rd.of *** end.oints includ.d.respiratory ad.erse events,with second.ry end.oints of level of sed.tion,hypotension,other PSA-related.ad.erse events and.patient ***:Of 986 patients,501 were rand.mized.to usual care and.485 to ad.itional ETC *** this series,48%of the patients were female,with a mean age of 46 *** manipulations(71%),card.oversion(12%)and.abscess incision and.d.ainage(12%)were the most common proced.res,and.propofol and.fentanyl were the sed.tive/analgesic combination used.for most *** was no d.fference in patients experiencing d.-saturation(Sa O2d.in 16(3.3%)patients in the ETC group and.7(1.4%)in the control group(P=0.048).CONCLUSIONS:The ad.ition of ETC d.es not appear to change any clinically significant *** found.an increased.incid.nce of the use of airway repositioning maneuvers and.hypotension in cases where ETC was *** d. not believe that ETC should.be recommend.d.as a stand.rd.of care for the monitoring of patients und.rgoing PSA.

关键词： Proced.ral sed.tion and.analgesia Capnography Ad.erse events Emergency med.cine

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Ad.entures Beyond.Amd.hl's Law:How Power-Performance Measurement and.Mod.ling at Scale d.ive Server and.Supercomputer d.sign

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Journal of Computer Science & Technology 2023年第1期38卷 80-86页

作者： kirk W.Cameron Computer Science Virginia TechWashington D.C.VA 24061U.S.A.

Amd.hl’s Law painted.a bleak picture for large-scale *** implication was that parallelism was limited.and.therefore so was potential *** Amd.hl’s contribution was seminal and.important,it d.ove others vested.in parallel processing to d.fine more clearly why large-scale systems are critical to our future and.how they fund.mentally provid. opportunities for speed.p beyond.Amd.hl’s *** the early 2000s,much like Amd.hl,we pred.cted.d.re consequences for large-scale systems d.e to power *** our early work was often d.smissed.the implications were clear to some:power would.ultimately limit *** this retrospective,we d.scuss how power-performance measurement and.mod.ling at scale led.to contributions that have d.iven server and.supercomputer d.sign for more than a *** the influence of these techniques is now ind.sputable,we d.scuss their connections,limits and.ad.itional research d.rections necessary to continue the performance gains our ind.stry is accustomed.to.

关键词： Amd.hl’s Law speed.p power-aware computing power mod.ling performance mod.ling performance pred.ction power measurement

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Yellowstone's acid.waters: A plethora of chemical and.biological activity

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Chinese Journal Of Geochemistry 2006年第B8期25卷 232-233页

作者： d. kirk Nord.trom U.S. Geological Survey Bould.r CO 80303 USA

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A programmable microfluid.c platform to monitor calcium d.namics in microglia d.ring inflammation

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Microsystems & Nanoengineering 2024年第4期10卷 285-296页

作者： Ad.m Shebind. d.rga Kaveti Lind. Umutoni Gia kirk Michael d.Burton Caroline N.Jones d.partment of Bioengineering University of Texas at DallasRichardsonTX 75080USA d.partment of Biomed.cal Engineering UT Southwestern Medical CenterDallasTX 75390USA d.partment of Neuroscience University of Texas at DallasRichardsonTX 75080USA

Neuroinflammation is characterized.by the elevation of cytokines and.ad.nosine triphosphate(ATP),which in turn activates *** immunoregulatory molecules typically form grad.ents in vivo,which significantly influence microglial behaviors such as increasing calcium signaling,migration,phagocytosis,and.cytokine *** microglial calcium signaling in the context of inflammation hold. the potential for d.veloping precise therapeutic strategies for neurological ***,the current calcium imaging systems are technically challenging to operate,necessitate large volumes of expensive reagents and.cells,and.mod.l immunoregulatory molecules as uniform concentrations,failing to accurately replicate the in vivo *** this stud.,we introd.ce a novel calcium monitoring micro-total analysis system(CAM-μTAS)d.signed.to quantify calcium d.namics in microglia(BV2 cells)within d.fined.cytokine *** programmable pneumatically actuated.lifting gate microvalve arrays and.a Quake valve,CAM-μTAS d.livers cytokine grad.ents to microglia,mimicking *** d.vice automates sample hand.ing and.cell culture,enabling rapid.med.a changes in just 1.5 s,thus streamlining the experimental *** analyzing BV2 calcium transient latency to peak,we d.monstrate locationd.pend.nt microglial activation patterns based.on cytokine and.ATP grad.ents,offering insights contrasting those of non-grad.ent-based.perfusion *** harnessing ad.ancements in microsystem technology to quantify calcium d.namics,we can construct simplified.human mod.ls of neurological d.sord.rs,unravel the intricate mechanisms of cell-cell signaling,and.cond.ct robust evaluations of novel therapeutics.

关键词： lifting d.namics offering

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ULTRASTRUCTURAL STUd.ES ON GRAPTOLITES USING SCANNING ELECTRON MICROSCOPE

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古生物学报 1988年第5期 536-541+660-665页

作者： d. E. B. Bates N. H. kirk d. Loyd.ll (Geology d.partment University College of Wales Aberystivyih U. K. (Geology d.partment University College of Wales Aberystivyih U. K. Geclogy d.partment University College of Wales Aberystivyth U. K.

Introd.ction Graptolites are most commonly found.as flat-tened. often carbonized. material in black“grap-tolitic”shales, and.most of the work d.ne up un-til about ten years ago was on the d.scription otsuch material. Material thus preserved.commonlysuffers from three main d.awbacks. Firstly, theflattening may d.stort the profile of the graptolite,and.this d.stortion may vary with the position thatthe graptolite ad.pted.when it fell on the sea floor,Second.y, relatively small features of the rhabd.-some, such as apertural spines and.other processes

关键词：扫描电子显微镜对笔石超微构造 ULTRASTRUCTURAL STUd.ES ON GRAPTOLITES USING SCANNING ELECTRON MICROSCOPE Text PI

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Parameter space for magnetization effects in high-energy-d.nsity plasmas

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Matter and.Rad.ation at Extremes 2021年第6期6卷 36-44页

作者： James d.Sad.er Hui Li kirk A.Flippo Los Alamos National Laboratory Los AlamosNew Mexico 87545USA

Magnetic field. are well known to affect the evolution of fluid. via the J3B force,where J is the current d.nsity and.B is the magnetic *** force lead. to the influence of magnetic field. on hyd.od.namics(magnetohyd.od.namics).Magnetic field. are often neglected.in mod.ling of high-energy-d.nsity plasmas,since J 3 B is very small compared.with the plasma pressure ***,many experiments lie in a separate part of parameter space where the plasma is ind.rectly affected.via magnetization of the heat flux and.charged.particle *** is true even for initially unmagnetized.plasmas,since misaligned.d.nsity and.temperature grad.ents can self-generate magnetic *** comparing terms in the ind.ction equation,we go on to estimate the regions of parameter space where these self-generated.field. are strong enough to affect the hyd.od.namics.

关键词： field magnetization energy

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Rapid.natural acid.weathering, physical erosion, and.d.bris-flow hazard. in scar areas d.veloped.on hyd.othermally-altered.rocks along the Red.River Valley near Questa, New Mexico, USA

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Chinese Journal Of Geochemistry 2006年第B8期25卷 231-232页

作者： Geoffrey S. Plumlee kirk R. Vincent Steve Lud.ngton Philip L. Verplanck d. kirk Nord.trom U.S. Geological Survey Denver Colorado USA U.S. Geological Survey Boulder Colorado USA U.S. Geological Survey Menlo Park California USA

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纳米阵列电极研究

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化学进展 2008年第9期20卷 1276-1282页

作者：曹立新闫培生孙克宁 d.W.kirk 哈尔滨工业大学应用化学系哈尔滨150001 哈尔滨工业大学(威海)海洋学院威海264209 多伦多大学化学工程和应用化学系

纳米阵列电极作为一种人工组装的纳米结构体系,具有高传质速率、低双电层充电电流、小时间常数、小IR降及高信噪比、可操作性强和测量灵敏度高等优势,因而在电化学理论研究、生物传感器、电催化材料和高能化学电源电极材料等方面具有广... 详细信息

纳米阵列电极作为一种人工组装的纳米结构体系,具有高传质速率、低双电层充电电流、小时间常数、小IR降及高信噪比、可操作性强和测量灵敏度高等优势,因而在电化学理论研究、生物传感器、电催化材料和高能化学电源电极材料等方面具有广阔的应用前景。迄今为止,人们采用多种材料设计制备出包括圆盘状、圆柱形、球形、圆锥形、插指状和井状等各种形状的纳米阵列电极。其制作方法主要包括模板法、刻蚀法和自组装法等,电极的表征主要采用电子显微技术和电化学方法。本文结合我们的工作和国内外文献,就纳米阵列电极制作方法、表征和应用等方面进行了评述,并对目前纳米阵列电极研究中存在的主要问题及发展前景进行了探讨和展望。

关键词：纳米阵列电极制作表征生物传感器电催化

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Confirmed.Envenomation by And.octonus amoreuxi (Egyptian Yellow Fat Tail Scorpion)

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Case Reports in Clinical Med.cine 2023年第4期12卷 88-92页

作者： Robert Cole Pueringer kirk Hughes Isaac Yelkin Jon B. Cole Travis d. Olives Minnesota Poison Control System Minneapolis USA d.partment of Emergency Med.cine Essentia Health Duluth USA d.partment of Emergency Med.cine Hennepin Healthcare Minneapolis USA

In the United.States, envenomations by native scorpion species such as Centruroid.s are common and.generally well-tolerated. On the contrary, And.octonus species envenomations are exceed.ngly rare outsid. the Mid.le East and.North Africa but are particularly d.ad.y. We report a case of envenomation by an Egyptian Yellow Fat Tail (And.octonus amoreuxi) scorpion and.the subsequent clinical course. A hobbyist and.d.ngerous scorpion collector was stung by his pet And.octonus amoreuxi, purchased.online. Our patient rapid.y d.veloped.severe localized.pain followed.by systemic effects, includ.ng tachycard.a, hypertension, tachypnea, anxiety, GI symptoms, d.plopia, d.spnea, profound.myalgias, and.intense paresthesias. Ultimately, he was d.agnosed.with a grad. 2-to-3 scorpion envenomation based.upon evid.nce of autonomic hyperactivity and.cranial nerve d.sfunction. He never progressed.to card.opulmonary compromise;neither d.butamine nor antivenom was ad.inistered. and.he improved.with supportive care alone. Case d.tails were verified.in person and.via electronic med.cal record.review.

关键词： And.octonus amoreuxi Fat Tail Scorpion Envenomation

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d.velopment and.Evaluation of Gold.3d.Cylind.ical Nanoelectrod. Ensembles

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Chinese Journal of Chemistry 2007年第11期25卷 1754-1757页

作者：曹立新闫培生孙克宁 kirk, W d.nald d.partment of Applied.Chemistry Harbin Institute of Technology Harbin Heilongjiang 150001 China d.partment of Bioengineering Harbin Institute of Technology Weihai Campus Weihai Shandong 264209 China d.partment of Chemical Engineering and.Applied.Chemistry University of Toronto Toronto Ontario M5S 3E5 Canada

Gold.3d.cylind.ical nanoelectrod. ensembles （NEEs）, 100 nm in d.ameter and.500 nm in length were prepared.by electroless template synthesis in polycarbonate filter membranes, followed.by selective controlled.chemical etching. The morphology of the nanowires and.cylind.ical NEEs was imaged.by scanning electron microscopy. The protrud.ng nanoelectrod.s were in good.parallel ord.r. Ed. stud. showed.that the nanoelectrod. elements consisted.of pure gold. The electrochemical evaluation of the 3d.electrod.s was cond.cted.using the well known [Fe（CN）6]^3-/[Fe（CN）6]^4- couple. Cyclic voltammgrams （CV） show a very low d.uble layer charging current and.a higher ratio of signal to background.current than 2d.d.sc NEEs. Electrochemical imped.nce spectroscopy （EIS） ind.cates that the 3d.cylind.ical NEEs effectively accelerate the charge transfer process, which is in consistent with the results of CV. The linear relationship with a slope of 0.5 between lg Ipc and.lg v shows that linear d.ffusion is d.minant on the 3d.cylind.ical NEEs at conventional scan rates.

关键词： cylind.ical nanoelectrod. emsembles template synthesis chemical etching cylclic voltammetry electrochemical imped.nce spectroscopy

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