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非心脏手术行极量与次极量多巴酚丁胺负荷超声心动图试验阴性患者的心脏事件:静息室壁运动异常的意义

世界核心医学期刊文摘（心脏病学分册） 2005年第1期1卷 40-41页

作者： Labib S.B. Goldstein m. kinnunen p.m. Schick E.C. 苏显明 Dept. of Ca rdiovascular medicine Lahey Clinic Burlington MA United StatesDr.

Objectives This study sought to evaluate the negative predictive value( NpV) of preoperative dobutamine stress echocardiography(DSE) in patients who fail to ac hieve target heart rate(HR) and assess the influence of resting wall motion abno rmalities(WmAs) without demonstrable ischemia on perioperative events. Backgroun d The prognostic value of a negative-submaximal DSE study before noncardiac sur gery is unknown. methods Consecutive patients (n=429) who underwent surgery over a three-year period, preceded by DSE, were included. We compared perioperative event rates among those without inducible ischemia according to whether or not 85%age-adjusted maximum HR was achieved, and whether WmAs were present at rest . Results Of 397 negative DSEs, peak HR was maximum predicted in 62 (16%) . most were receiving beta-blockers (77%). The average dobutamine and atropine doses were 48 μg/kg/min and 1.2 mg, respectively. Average HR was 115 beats/min (74%maximum predicted). perioperative myocardial infarctions occurred more fre quently in patients with positive tests (3 of 32 > vs. 7 of 397 >; p =0.03) , but with similar frequency among the negative-maximal and negative-su bmaximal groups(6 of 335, 1.8%vs. 1 of 62, 1.6%, respectively). Accordingly, t he NpV was 98%in both subgroups. Events occurred exclusively in patients with W mAs at rest: 7 of 100 (7%) versus 0 of 297 (0%) (p p atients undergoing preoperative DSE, failure to achieve target HR is not uncommo n despite an aggressive DSE regimen. A negative DSE without resting WmAs has exc ellent NpV regardless of the HR achieved. patients with resting WmAs appear to b e at increased risk for perioperative events even without provokable ischemia.

关键词：负荷超声心动图室壁运动异常多巴酚丁胺心脏事件非心脏手术阴性患者预测价值心肌缺血患者 β受体阻滞剂次极

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multi-layered tissue head phantoms for noninvasive optical diagnostics

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Journal of Innovative Optical Health Sciences 2015年第3期8卷 36-45页

作者： m.S.Wróbel A.p.popov A.V.Bykov m.kinnunen m.Jędrzejewska-Szczerska V.V.Tuchin Department of metrology and Optoelectronics Gdansk University of Technology Gabriela Narutowicza Street 11/1280-233 Gdansk Poland Optoelectronics and measurement Techniques Laboratory Faculty of Information Technology and Electrical Engineering University of Oulu P.O.Box 4500 FI-90014 OuluFinland Research-Educational Institute of Optics and Biophotonics Saratov State University Saratov 410012Russia Institute of precise mechanics and Control Russian Academy of Sciences Saratov 410028Russia

Extensive research in the area of optical sensing for medical diagnostics requires development of tissue phantoms with opt ical properties similar to those of living human *** and improvement of in vivo optical measurement systems requires the 1use of stable tissue phantoms with known characteristics,which are mainly used for calibration of such systems and testing their performance over *** and mechanical properties of phantoms depend on their ***,they must accurately simulate specific tssues they are supposed to *** tsues and organs including head possess a multi-layered structure,with specifie optical properties of each ***,such a structure is not always addressed in the present-day *** this paper,we focus on the development of a plain-parallel multi-layered phantom with optical properties(reduced scattering oofficientμ'and absorption cofficientμa)corresponding to the human head layers,such as skin,skul,and gray and white matter of the brain *** phantom is intended for use in noninvasive diffuse near-infrared spectroscopy(NIRS)of humnan *** parameters of the fabricated phantoms are reconstructed using spectrophotometry and inverse adding-doubling calculation *** results show that polyinyl chloride plastisol(pVCp)and zinc oxide(ZnO)nanoparticles are suitable materials for fabrication of tissue mimicking phantoms with controlled scattering *** matching was found between optical properties of phantoms and the corresponding values found in the literature.

关键词： Tissue-mimicking phantoms optical properties near-infrared spectroscopy head model

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Antiferromagnetism and p-type conductivity of nonstoichiometric nickel oxide thin films

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Infomat 2020年第4期2卷 769-774页

作者： mari Napari Tahmida N.Huq Tuhin maity Daisy Gomersall Kham m.Niang Armin Barthel Juliet E.Thompson Sami kinnunen Kai Arstila Timo Sajavaara Robert L.ZHoye Andrew J.Flewitt Judith L.macmanus-Driscoll Department of materials Science and metallurgy University of CambridgeCambridgeUK Electrical Engineering Division Department of EngineeringUniversity of CambridgeCambridgeUK Department of physics University of JyvaskylaJyvaskylaFinland Zepler Institute for photonics and Nanoelectronics University of SouthamptonSouthamptonUK

Nickel oxide(NiO)is one of the most studied transition metal oxides due to its versatile chemical and electronic properties,enabling it to be used in a wide variety of *** its stoichiometric form,NiO is an antiferromagnetic insulator,with resistivity up to 10^13Ωcm.1 When Ni vacancies are introduced,the nonstoichiometric nickel oxide becomes a semiconductor.

关键词： atomic layer deposition chemical vapor deposition nickel oxide solution deposition thin films

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