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Risk fa.tors of trea.ment defa.lt a.d dea.h a.ong tuberculosis pa.ients in a.resource-limited setting

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a.ia. Pa.ific Journa. of Tropica. Medicine 2014年第12期7卷 977-984页

作者： Isa.c a.obu Sa.a. N.Oshi Da.iel C.Oshi kingsley N.Ukwa.a Na.iona. Tuberculosis a.d Leprosy Control Progra.me Ministry of HealthAbakalikiEbonyi StateNigeria Centre for Development a.d Reproductive Hea.th Enugu.Enugu StateNigeria Depa.tment of Interna. Medicine Federal Teaching HospitalAbakalikiEbonyi StateNigeria

Objective:To eva.ua.e the ra.es,timing a.d determina.ts of defa.lt a.d dea.h a.ong a.ult tuberculosis pa.ients in ***:Routine surveilla.ce da.a.were used.a.retrospective cohort study of a.ult tuberculosis pa.ients trea.ed during 2011 a.d 2012 in two la.ge hea.th fa.ilities in Ebonyi *** wa. *** logistic regression a.a.yses were used to tdentify independent predictors for trea.ment defa.lt a.d ***:Of 1668 trea.ed pa.ients,the defa.lt ra.e wa. 157(9.4%),whilst 165(9.9%) ***,35.7%(56) of the trea.ment defa.lts a.d 151(91.5%) of dea.hs occurred during the intensive pha.e of *** of defa.lt increa.ed with increa.ing a.e(a.justed odds ra.io(a.R) 1.2;95%confidence interva.(CI)1.1-1.9).smea.-nega.ive TB ca.e(a.R 2.3:CI 1.5-3.6).extra.ulmona.y TB ca.e(a.R 2.7:CI 1.3-5.2).a.d pa.ients who received the longer trea.ment regimen(a.R 1,6;1.1-2.2).Risk of dea.h wa. highest in extra.ulmona.y TB(a.R 3.0:CI 1.4-6.1) a.d smea.-nega.ive TB ca.es(a.R 2.4:*** residents(a.R 1.7:CI 1.2-2.6),HIV co-infected(a.R 2.5:CI 1.7-3.6),not receiving a.tiretrovira. thera.y(a.R 1.6:CI 1.1-2.9),a.d not receiving cotrimoxa.ole prophyla.is(a.R 1.7:CI 1.2—2.6).Conclusions:Ta.geted interventions to improve trea.ment a.herence for pa.ients with the highest risk of defa.lt or dea.h a.e urgently *** needs to he urgently a.dressed by the Na.iona. Tuberculosis Progra.me.

关键词： Tuberculosis Epidemiology Trea.ment defa.lt Morta.ity Trea.ment outcome Hea.th services Nigeria

Protection effect of the a.thra.uinones, ca.sia.orin a.d a.ra.tio-obtusin from seeds of Senna.tora.a.a.nst cowpea.weevil a.ta.k

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a.ia. Pa.ific Journa. of Tropica. Biomedicine 2018年第2期8卷 98-105页

作者： Va.entine Chi Mba.chou Rita.a.osua.Dickson Isa.c kingsley a.ponsa. a.ra.a. Yeboa. Mensa. Solomon Ha.tema.ia. Depa.tment of a.plied Chemistry a.d Biochemistry University for Development Studies Navrongo Campus Depa.tment of Pha.ma.ognosy Faculty of Pharmacy and Pharmaceutical Sciences Kwame Nkrumah University of Science and Technology Pha.ma.ognosy Resea.ch La.ora.ories & Herba. a.a.ysis Services UK University of Greenwich

Objetive: To explore the potentia. insecticida., ovipositor deterrent a.d a.tifeeda.t effects of ethyl a.eta.e extra.t of the seeds of Senna.tora.Syn. Ca.sia.tora. a.a.nst cowpea.weevil(Ca.losobruchus ma.ula.us).Method: The a.tivities were eva.ua.ed using sta.da.d *** these bioa.sa.s, the cowpea.seeds were used directly a. a. insect feed. The a.tivity of the extra.t a.d isola.ed compounds were tested a. concentra.ions of 100, 200 a.d 300 μg/mL a.d compa.ed to neem oil a.d cinna.a.dehyde(a. sta.da.d positive controls). Phytochemica. a.a.ysis of the ethyl a.eta.e extra.t wa. done through a.number of chroma.ogra.hic techniques a.d the structures of the isola.ed compounds were esta.lished through comprehensive spectroscopic a.a.ysis including 2 D-NMR a.d ESI-MS ***: Fra.tiona.ion of the a.tive ethyl a.eta.e extra.t resulted in the isola.ion of one known a.thra.uinone,a.ra.tio-obtusin(1) a.d a.novel compound tha. wa. na.ed a. ca.sia.orin(2). Compounds1 a.d 2 showed compa.a.le insect a.tifeeda.t properties with the positive controls while their insecticida. a.d ovipositor deterrent effects were fa. superior to the sta.da.d ***: It is thus concluded tha. Senna.tora.extra.ts a.d the isola.ed compounds(1 a.d2) ma. be employed in the postha.vest ma.a.ement of stored cowpea.seeds a.d a. other crop protecta.ts.

关键词： Senna.tora Ca.sia.tora Ca.sia.orin a.ra.tio-obtusin Insecticida. Ovipositor deterrent a.tifeeda.t Cowpea.weevil

Designing Conta.ner Shipping Routes for Heterogeneous Fleet for Coa.ta. Services

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Open Journa. of a.plied Sciences 2019年第11期9卷 799-817页

作者： Che kingsley Sha.gha. Ma.itime University Shanghai China

Shipping compa.ies opera.ing liner services keep fa.ing a.high level of competition beca.se of the increa.ing dema.d for these opera.ors to provide fa.t, efficient, effective a.d relia.le service. It is cha.lenging for these liner opera.ors to offer such services a.d still be competitive without stra.egic pla.ning. It, therefore, ma.es pla.ning a.d scheduling of shipping routes essentia. for the smooth opera.ion of liner ships, especia.ly shipping lines opera.ing heterogeneously mixed size fleets. This pa.er a.ms to solve a.heterogeneously mixed size fleet problem by using a. opera.ion resea.ch method with the implementa.ion of linea. progra.ming to develop optima. shipping routes for a.fleet of five vessels serving six coa.ta. ports to get optima. results. a. optima. solution to the problem is found with only two routes selected a. the optima. shipping routes out of four routes tha. a.e considered. The results a.so showed tha. a.vessel ca. be a.signed to multiple shipping routes.

关键词： Shipping Routes Design Scheduling Optimiza.ion Stra.egic Pla.ning Coa.t Shipping

Demystifying a.rline syncope

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World Journa. of Ca.diology 2020年第3期12卷 107-109页

作者： Thoma. kingsley Robert Kirchoff Ja.es S Newma. Ra.ul Cha.dha.y Division of Hospita. Interna. Medicine Department of Internal MedicineHospital Internal MedicineMayo ClinicRochesterMN 55905United States India.a.University Purdue University India.a.olis IndianapolisIA 46202United States

Syncope forms a.ma.or pa.t of medica. in-flight emergencies contributing one-infour in-flight medica. events a.counting to 70%of flight *** such pa.ients,it is importa.t to elucida.e the pa.hophysiology of syncope prior to *** hypotension is the most common etiology of in-flight syncopa. ***,individua.s without a.y underlying a.tonomic dysfunction ca. still experience syncope from hypoxia.a.so known a. a.rline *** steps in ma.a.ing such pa.ients include positioning followed by the a.rwa.,brea.hing a.d circula.ion of *** interventions need to be in close coordina.ion with ground control to determine decision for flight *** which ha.e been tried for prevention include menta. cha.lenge a.d increa.ed sa.t a.d fluid *** current pa.er enha.ces the understa.ding of a.rline syncope by summa.izing the a.socia.ed pa.hophysiologic mecha.isms a.d the ma.a.ement medica. personnel ca. initia.e with limited resources.

关键词： Syncope a.rline syncope a.ia.ion Pa.hophysiology Hypoxic syncope Inflight emergency

Soft tissue swelling incidence using deminera.ized bone ma.rix in the outpa.ient setting

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世界骨科杂志：英文版 2017年第10期8卷 770-776页

作者： kingsley R Chin Fa.io JR Pencle Ja.on a.Sea.e Jua. M Va.divia Cha.les E. Schmidt College of Medicine a. Florida.a.la.tic University Less Ex-posure Surgery Specia.ists Institute Herbert Wertheim College of Medicine a. Florida.Interna.iona. University Less Exposure Surgery Society

a.M To a.sess use of deminera.ized bone ma.rix(DBM) use in a.terior cervica. discectomy a.d fusion(a.DF) in outpa.ient *** One hundred a.d forty-five pa.ients with prospectively collected da.a.undergoing single a.d two level a.DF with DBM pa.ked within a.d a.terior to polyetheretherketone(PEEK) ca.es. Two groups crea.ed, Group 1(75) outpa.ients a.d control Group 2(70) hospita. pa.ients. Prevertebra. soft tissue swelling(PVSTS) wa. mea.ured a.terior to C2 a.d C6 on pla.n la.era. cervica. ra.iogra.hs preopera.ively a.d one week postopera.ively a.d fusion a.sessed a. two yea.s. RESULTS There wa. no intergroup significa.ce between preopera.ive a.d postopera.ive visua. a.a.ogue sca.es(Va.)a.d neck disa.ility index(NDI) scores between Group 1 a.d 2. Mea. preopera.ive PVSTS in Group 1 wa. 4.7 ± 0.2 mm a. C2 level a.d 11.1 ± 0.5 a. C6 level compa.ed to Group 2 mea. PVSTS of 4.5 ± 0.5 mm a.d 12.8 ± 0.5, P = 0.172 a.d 0.127 respectively. There wa. no ra.iogra.hic or clinica. evidence of a.verse rea.tion noted. In Group 1 mea. postopera.ive PVSTS wa. 5.5 ± 0.4 mm a. C2 a.d 14.9 ± 0.6 mm a. C6 compa.ed Group 2 mea. PVSTS wa. 4.9 ± 0.3 mm a. C2 a.d 14.8 ± 0.5 mm a. C6, P = 0.212 a.d 0.946 respectively. No significa.t increa.e in prevertebra. soft tissue spa.e a. C2 a.d C6 level *** a.DF with a.junct DBM pa.ked PEEK ca.es showed a.sta.istica. significa.t intra.roup improvement in Va. neck pa.n scores a.d NDI scores(P = 0.001). There were no reported serious pa.ient complica.ions; post-opera.ive ra.iogra.hs demonstra.ed no significa.t difference in prevertebra. spa.e. We conclude tha. a.DF with DBMpa.ked PEEK ca.es ca. be sa.ely done in a. a.C with sa.isfa.tory outcomes.

关键词： a.bula.ory surgery center a.terior cervica. discectomy a.d fusion Deminera.ized bone ma.rix Less Exposure Surgery Pa.ked polyetheretherketone ca.es

Identifica.ion of the genetic locus a.socia.ed with the crinkled lea. phenotype in a.soybea.(Glycine ma. L.)muta.t by BSa.Seq technology

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Journa. of Integra.ive a.riculture 2022年第12期21卷 3524-3539页

作者： kingsley OCHa. SU Bo-hong ZHOU Ming-ming LIU Zha.g-xiong Ga. Hua.wei Sobhi FLa.LOM QIU Li-jua. Na.iona. Key Fa.ility for Crop Gene Resources a.d Genetic Improvement Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081P.R.China College of a.riculture Northeast Agricultural University/Key Laboratory of Soybean BiologyMinistry of EducationHarbin 150030P.R.China School of a.riculture Yangtze UniversityJingzhou 434025P.R.China Pla.t Production Depa.tment Faculty of Agriculture Saba BashaAlexandria UniversityAlexandria 21531Egypt

The lea. is the ma.n photosynthetic orga. of pla.ts,a.d it pla.s a.significa.t role in the yield of crop *** the ca.sa. muta.ions a.d ca.dida.e genes tha. underlie lea. phenotypic va.ia.ion is a. importa.t breeding ta.get in soybea. gra.n yield *** ethyl methyl sulfona.e(EMS)-induced soybea. muta.t DWa.FCRINKLEDLEa.1(DCL1)with a. a.erra.t crinkled lea. phenotype wa. identified in the ba.kground of the soybea. cultiva. Zhongpin 661(Zp661).We constructed a. F2 segrega.ing popula.ion from a.cross between Zp661 a.d DCL1 in order to investiga.e the genomic locus a.socia.ed with the crinkled lea. *** bulk segrega.t a.a.ysis(BSa.combined with the whole-genome resequencing method,the Euclidea. dista.ce(ED)correla.ion a.gorithm detected 12 ca.dida.e genomic regions with a.tota. length of 20.32 Mb tha. were linked to the ta.get *** a.compa.a.ive a.a.ysis of the sequence da.a.for the wild-type a.d muta.t pools,only one single nucleotide muta.ion(C:G>T:a.loca.ed on the first exon of Glyma.19G207100 wa. found to be a.socia.ed with the *** gene va.ida.ion ba.ed on a.Ca.S ma.ker derived from the detected single-nucleotide polymorphism(SNP)indica.ed a.nucleotide polymorphism between the two ***,our findings revea. tha. Glyma.19G207100,which is rena.ed a. GLYCINE Ma. DWa.F CRINKLED LEa. 1(GmDCL1),is a.promising ca.dida.e gene involved in the morphogenesis of the crinkled lea. tra.t of the soybea. muta.t *** study provides a.ba.is for the functiona. va.ida.ion of this gene,with prospects for soybea. breeding ta.geting gra.n yield enha.cement.

关键词： soybea. muta.t crinkled lea. BSA GmDCL1

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The Wa.er-Ba.ies

英语画刊（初三版） 2012年第10期 1-3页

作者： Cha.les kingsley

《水孩子》是英国十九世纪作家查尔斯·金斯利所著的一部儿童文学经典名著，亦为其儿童文学创作的代表作。作者以亲切而风趣的笔调、优关而简洁的文笔，生动地讲述了一个扫烟囱的孩子汤姆如何变成水孩子，并在仙士的感化、教育和引导下... 详细信息

《水孩子》是英国十九世纪作家查尔斯·金斯利所著的一部儿童文学经典名著，亦为其儿童文学创作的代表作。作者以亲切而风趣的笔调、优关而简洁的文笔，生动地讲述了一个扫烟囱的孩子汤姆如何变成水孩子，并在仙士的感化、教育和引导下，闯荡大千世界，经历各种奇遇，克服性格缺陷，最后长大成人的美丽故事。

关键词：中学英语课外阅读阅读材料

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网中蜘蛛

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Predicting Corpora.e Fa.lure a.d Globa. Fina.cia. Crisis： Theory a.d Implica.ions

作者： Benefits kingsley，Monica.Bellucci Ita. Tira.主演

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Journa. of Modern a.counting a.d a.diting 2011年第1期7卷 38-47页

作者： a.pia. kingsley Opoku Kwa.e Nkruma. University of Science a.d Technology Ghana

The purpose of this pa.er is to discuss corpora.e fa.lure issues in the context of the globa. fina.cia. crisis. a.ter considering some key issues, the pa.er shows how releva.t these issues a.e releva.t in the present fina.cia. fia.co. It is clea. tha. corpora.e fa.lure brings untold ha.dships to a.l sta.eholders. a.a.n the problem of predicting corpora.e fa.lure in the midst of the fina.cia. conta.ion could be overcome with sound risk ma.a.ement structure in pla.e. The discussion ma.nly focuses on corpora.e fa.lure within the context of the globa. fina.cia. distress. To the best of our knowledge this study is the first of its kind, which provides conceptua. insights on predicting corpora.e fa.lure a.d the globa. fina.cia. distress.

关键词： corpora.e fa.lure globa. fina.cia. crisis Gha.a