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Frontiers in Biology 2018年第6期13卷 475-480页

作者： Jalali Seyyed Mostafa Morteza Abdollahi Atiyeh Hosseini Dehghani Karl Bozorg Ajami Marjan Azadeh kimia moiniafshar 7th Floor Bldg No.2SBUMSArabi AveDaneshjoo BlvdVelenjakTehranTehran 19839-63113Iran

Cancer and chemotherapy-induced malnutrition increase death, reduce the response to treatment, and increase multiple kinds of side effects. The aim of this study was to investigate the effects of Mediterranean-neutropenic diet on the nutritional status of acute myeloid leukemia patients under chemotherapy. 50 patients were divided into two groups by a random allocation scheme: the Mediterranean-neutropenic diet (n = 25) and the neutropenic diet group (n = 25). The intervention was implemented during a one month period. The nutritional status was evaluated based on PG-SGA. Serum albumin levels and dietary intake were also measured. After the intervention, the mean serum albumin level in the intervention group was significantly higher than the beginning of the study (p = 0.09) and in comparison with the control group (p = 0.01). Also, the mean serum albumin level in the control group significantly decreased at the end of the study compared to the beginning of the study (p = 0.03). After intervention, the nutritional status of the patients in the intervention group was significantly improved compared to the control group. In general, based on the results of this study, the Mediterranean neutropenic diet improves nutritional status during chemotherapy by increasing food intake, preventing weight loss and increasing serum albumin levels

关键词： nutritional status Mediterranean diet neutropenic diet AML chemotherapy

Diagnosis of choroid plexus papilloma: Current perspectives and future directions

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Cancer Pathogenesis and Therapy 2024年第3期2卷 173-179页

作者： Esma'il Akade Fereshteh Aslani kimia Verdi Mohammad Bahadoram Gholam Abbas Kaydani Department of Medical Virology School of MedicineAhvaz Jundishapur University of Medical SciencesAhvaz ***Iran Department of Laboratory Sciences School of Allied Medical SciencesAhvaz Jundishapur University of Medical SciencesAhvaz ***Iran Department of Physiology School of MedicineAhvaz Jundishapur University of Medical SciencesAhvaz ***Iran Department of Neurology School of MedicineAhvaz Jundishapur University of Medical SciencesAhvaz ***Iran

Choroid plexus papilloma(CPP)is a rare,slow-growing,and typically benign brain tumor that predominantly affects *** is characterized by well-defined circular or lobulated masses in the ventricles,leading to symptoms related to increased intracranial pressure and *** diagnosis relies on a combination of clinical presentation,imaging findings,and histological *** World Health Organization(WHO)classification categorizes choroid plexus tumors into CPP(Grade Ⅰ),atypical CPP(aCPP,Grade Ⅱ),and choroid plexus carcinoma(CPC,Grade Ⅲ).This article reviewed current diagnostics modalities and explored the emergence of new diagnostic methods for *** on molecular markers and genetic alterations associated with CPP is ongoing,and some potential markers have been *** results offered insights into potential therapeutic targets and personalized treatment approaches for *** in radiomics and liquid biopsy hold promise for improving diagnostic accuracy and monitoring treatment outcomes for choroid plexus *** can provide quantitative data from imaging studies,whereas liquid biopsy can analyze tumor-derived genetic material and molecular markers from body fluids,such as cerebrospinal fluid(CSF)and *** rapidly evolving fields of molecular and genetic research and novel diagnostic methods require continuous updates and advancements before their application in clinical *** hope that these advancements will lead to earlier and more precise diagnoses,better treatment options,and improved outcomes in patients with CPP and other brain tumors.

关键词： Cerebral ventricle neoplasms Biomarkers Neuroimaging Translational research Histopathological features

Optimal Day-ahead Dynamic Pricing of Grid-connected Residential Renewable Energy Resources Under Different Metering Mechanisms

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Journal of Modern Power Systems and Clean Energy 2023年第1期11卷 168-178页

作者： kimia Parandeh Abed Bagheri Shahram Jadid Center of Excellence for Power System Automation and Operation School of Electrical EngineeringIran University of Science and Technology(IUST)TehranIran

Nowadays,grid-connected renewable energy resources have widespread applications in the electricity ***,providing household consumers with photovoltaic(PV)systems requires bilateral interfaces to exchange energy and *** addition,residential consumers’contribution requires guaranteed privacy and secured data *** dynamic pricing is one of the incentive-based demand response methods that has substantial effects on the integration of renewable energy resources with smart grids and social *** metering mechanisms of renewable energy resources such as feed-in tariffs,net metering,and net purchase and sale are important issues in power grid operation *** this paper,optimal condition decomposition method is used for dayahead dynamic pricing of grid-connected residential renewable energy resources under different metering mechanisms:feed-intariffs,net metering,and net purchase and sale in conjunction with carbon emission *** to the stochastic nature of consumers’load and PV system products,uncertainties are considered in a two-stage decision-making *** results demonstrate that the net metering with the satisfaction average of 68%for consumers and 32%for the investigated electric company leads to 28%total load *** the case of net purchase and sale mechanism,a satisfaction average of 15%for consumers and 85%for the electric company results in 11%total load *** feed-in-tariff mechanism,in spite of increased social welfare,load reduction does not take place.

关键词： Dynamic pricing renewable energy resources feed-in-tariffs net metering net purchase and sale stochastic decision-making

Street network patterns for mitigating urban heat islands in arid climates

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International Journal of Digital Earth 2023年第1期16卷 3145-3161页

作者： kimia Chenary Ali Soltani Ayyoob Sharifi Department of Architecture and Urban Planning Bojnourd UniversityBojnourdIran Injury Studies FHMRIBedford ParkAustralia UniSA Business University of South AustraliaAdelaideAustralia Department of Urban Planning Shiraz UniversityShirazIran The IDEC Institute and Network for Education and Research on Peace and Sustainability(NERPS) Hiroshima UniversityHigashihiroshimaJapan

This study explores the impact of street pattern measurements on urban heat islands(UHI)in the arid climate of Mashhad,*** Landsat-8 top-of-the-atmosphere(TOA)brightness images from 2013 to 2021,average values of normalized difference vegetation index(NDvI)and land surface temperature(LST)were *** pattern measurements,including closeness-centrality,straightness,and street orientation,were employed to analyse the patterns in each *** results indicated that districts with higher straightness and lower closeness-centrality exhibit,cooler surface *** correlations were observed between LST and NDVl,straightness,and local *** research highlighted the importance of considering street network measurements in long-term urban planning and design to mitigate the UHI effect in arid regions.A moderate grid street pattern with a reasonable distribution of green spaces throughout the region is suggested to reduce surface temperatures *** pattern indexes,such as straightness and local closeness-centrality,are identified as significant factors in urban design to mitigate *** findings have implications for urban planners,who can use this information to create street network patterns with lower UHI effects by reducing local closeness-centrality and increasing straightness.

关键词： Urban heat island Urban form Street network pattern Green space distribution

Microstructural evolution,mechanical properties,and corrosion resistance of a heat-treated Mg alloy for the bio-medical application

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Journal of Magnesium and Alloys 2019年第1期7卷 80-89页

作者： Mohammad Janbozorgi kimia Karimi Taheri Ali Karimi Taheri Department of Materials Science and Engineering Sharif University of TechnologyAzadi Ave.TehranIran School of Medicine Shahid Beheshti University of Medical ScienceTehranIran

During the recent years,some Mg based alloys have extensively been considered as a new generation of degradable and absorbable bio-medical *** this work,the Mg-2Zn-1Gd-1Ca(wt%)alloy as a new metallic bio-material was produced by the casting process followed by the heat *** samples of the alloy were solution treated at temperatures of 500,550,and 600°C and then quench aged at temperatures of 125,150,and 175°*** results of SEM-EDS examinations indicated that the alloy microstructure consists ofα-Mg matrix and the Ca_(2)Mg_(6)Zn_(3)and Mg_(3)Gd_(2)Zn_(3)secondary *** regard to the results of Vickers hardness test,the temperatures of 500°C and 150°C were selected as the optimum solutionizing and aging temperatures,***,the dissolution of casting precipitates and production of lattice distortion occurring after the solution treatment led to the reduction in ultimate shear strength up to 21%.But,the precipitation hardening and morphological changes taking place during the aging treatment improved the ultimate shear strength up to 32%.Furthermore,the results of electro-chemical and weight-loss measurements in a simulated body fluid indicated that the heat-treated alloy is a promising candidate for the Mg based alloys recently considered for the bio-medical applications.

关键词： Mg alloys Bio-medical applications Microstructural evolution Mechanical properties Corrosion resistance

Reversible heart failure in a patient with hypocalcemic cardiomyopathy

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Journal of Geriatric Cardiology 2021年第12期18卷 1063-1067页

作者： Mehrdad Jafari Fesharaki Nooshin Ahmadi kimia Karimi Taheri Department of Cardiology Shahid Beheshti University of Medical SciencesTehranIran School of Medicine Shahid Beheshti University of Medical SciencesTehranIran Research Institute for Endocrine Sciences Shahid Beheshti University of Medical SciencesTehranIran

The parathyroid gland is essential to maintaining the serum calcium level within the normal range by secreting the parathyroid hormone(PTH).Significant incidences of increased blood pressure,arrhythmia,left ventricular(LV)hypertrophy,and congestive heart failure(CHF)can occur in patients with parathyroid *** can cause dilated cardiomyopathy,whether this is *** caused by thyroidectomy and primary hypoparathyroidism are the greatest causes of hypocalcemic heart failure(HF).

关键词： cardiomyopathy parathyroid ventricular

Design and testing of a centralized protection scheme for micro-grids

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Journal of Central South University 2015年第10期22卷 3876-3887页

作者： Sohrab Mirsaeidi Dalila Mat Said Mohammad Wazir Mustafa Mohammad Hafiz Habibuddin kimia Ghaffari Centre of Electrical Energy Systems (CEES) Faculty of Electrical Engineering (FKE)Universiti Teknologi Malaysia (UTM) Young Researchers and Elites Club Saveh Branch Islamic Azad University

Micro-grids comprise low voltage distribution systems with distributed energy resources(DERs) and controllable loads which can operate connected to the medium voltage grid or islanded in a controlled coordinated way. This concept aims to move from "connect and forget" philosophy towards a full integration of DERs. Micro-grids can provide numerous economic and environmental benefits for end-customers, utilities and society. However, their implementation poses great technical challenges, such as a new philosophy in design of protection systems. In this work, a micro-grid protection scheme is presented based on positive-sequence component using phasor measurement units(PMUs) and a central protection unit(CPU). The salient feature of the proposed scheme in comparison with the previous works is that it has the ability to protect both radial and looped micro-grids against different types of faults with the capability of single-phase tripping. Furthermore, since the CPU is capable of updating its pickup values(upstream and downstream equivalent positive-sequence impedances of each line) after the first change in the micro-grid configuration(such as transferring from grid-connected to islanded mode and or disconnection of a line, bus, or DER either in grid-connected mode or in islanded mode), it can protect micro-grid against subsequent faults. Finally, in order to verify the effectiveness of the suggested scheme and the CPU, several simulations have been undertaken by using DIg SILENT Power Factory and MATLAB software packages.

关键词： micro-grid protection grid-connected mode islanded mode positive-sequence component

Astragalus adscendens extract shows antidiabetic effects through controlling oxidative stress,inflammation and apoptosis in streptozotocin-induced diabetic rats

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Asian Pacific Journal of Tropical Biomedicine 2023年第6期13卷 242-249页

作者： Yosra Raziani kimia Karami Hamid Reza Mohammadi Hossein Mahmoudvand Mohammad Nabi Moradi Javad Ghasemian Yadegari Nursing Department Al-Mustaqbal University College51001 HillahBabylonIraq Razi Herbal Medicines Research Center Lorestan University of Medical SciencesKhorramabadIran Molecular and Cellular Laboratory School of Allied MedicineLorestan University of Medical SciencesKhorramabadIran

Objective:To assess the effect of oral treatment of methanolic extract of the aerial parts of Astragalus adscendens in streptozotocin-induced diabetic ***:In order to induce diabetes,rats intraperitoneally received streptozotocin at 65 mg/*** adult male Wistar rats were allocated into six groups(10 rats per each)including the healthy control group,the diabetic group as well as the diabetic group treated with Astragalus adscendens methanolic extract at 50,100,and 200 mg/kg per day or glibenclamide(0.6 mg/kg/day)for 28 *** effects of Astragalus adscendens methanolic extract on the levels of glucose,insulin,alanine aminotransferase,alkaline phosphatase,aspartate aminotransferase,bilirubin,creatinine,urea,uric acid,total protein,albumin,triglyceride,cholesterol,α-amylase,oxidant/antioxidant enzymes,and inflammatory cytokines were *** time-PCR was also used for measuring the gene expression of caspase-3,Bcl2,and ***:The levels of glucose,cholesterol,triglyceride,creatinine,urea,uric acid,alanine aminotransferase,aspartate aminotransferase,alkaline phosphatase,bilirubin,and malondialdehyde considerably declined(P<0.001)in diabetic rats after treatment with Astragalus adscendens methanolic extract especially at a dose of 200 mg/*** addition,treatment with Astragalus adscendens methanolic extract noticeably increased the level of insulin,total protein,and albumin as well as improved the activities of catalase,glutathione peroxidase,and superoxide dismutase,as well as the expression levels of TNF-α,IL-1β,caspase-3,Bcl2 and Bax(P<0.001)compared to the diabetic control *** extract also inhibitedα-amylase in a dose-dependent manner with an IC_(50)value of 19.6μg/***:Astragalus adscendens methanolic extract shows potent antidiabetic,anti-inflammatory,anti-apoptotic,and antioxidant effects in diabetic ***,more studies are needed to verify the underlying mechanism of the effect of this plant extract and test its effica

关键词： Herbal medicines Astragalus adscendens Diabetes Antioxidant Antidiabetes Streptozotocin Antiinflammation

Brucellosis: Pathophysiology and new promising treatments with medicinal plants and natural antioxidants

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Asian Pacific Journal of Tropical Medicine 2018年第11期11卷 597-608页

作者： Mohsen Alizadeh Ali Safarzadeh Mahmoud Bahmani Fatemeh BeyranvAND Mehdi Mohammadi kimia Azarbaijani Mahmoud Rafieian-Kopaei Saber Abbaszadeh Razi Herbal Medicines Research Center Lorestan University of Medical Sciences Student Research Committee Lorestan University of Medical Sciences Biotechnology and Medicinal Plants Research Center Ilam University of Medical Sciences Medical Plants Research Center Basic Health Sciences Institute Shahrekord University of Medical Sciences

Brucellosis is an old, infectious and common zoonosis whose causative agents are Gramnegative bacteria from the Brucella genus. Brucellosis is transmitted through direct contactwith infected animals or using unpasteurized dairy products of goats, pigs, camels, sheep,buffalo and cows. Brucellosis is still the most common zoonosis in the world, with mostof cases occurring in developing countries. Today, an approach to traditional medicine andmedicinal plants, especially with regards to the repeated recommendations of the World HealthOrganization, is a necessity. One-third of chemical drugs are produced by using plants andthere is a high potential to produce more drugs from plants. Medicinal plants are helpful inthe management of various conditions, especially bacterial diseases. Although there is notenough scientific evidence regarding the clinical effectiveness of herbal drugs for the treatmentof brucellosis, there is strong evidence on the antimicrobial effects of herbal drugs to preventinfection. Therefore, this article seeks to describe the antibacterial effects of some plantderived essential oils or extracts, so that they can serve as promising choices to develop newanti-Brucella medications, as suitable alternatives to conventional antibiotics for brucellosis, asmuch as possible, taking into account the benefits of these herbal drugs.

关键词： Brucellosis Undulant fever Malta fever Herbal drugs Phytotherapy Antioxidant

Biotoxicity evaluation of zinc oxide nanoparticles on bacterial performance of activated sludge at COD,nitrogen,and phosphorus reduction

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Frontiers of Environmental Science & Engineering 2022年第2期16卷 51-62页

作者： Hasti Daraei kimia Toolabian Ian Thompson Guanglei Qiu Environmental Health Engineering Research Center Kerman University of Medical SciencesKermanIran Department of Environmental Health Engineering Faculty of Public HealthKerman University of Medical SciencesKermanIran Faculty of Agriculture and natural resources Lorestan UniversityKhorramabadIran Department of Engineering Science University of OxfordParks RoadOxford OX13PJUK School of Environment and Energy South China University of TechnologyGuangzhou 510006China

The unique properties and growing usage of zinc oxide nanoparticles increase their release in municipal wastewater treatment ***,these nanoparticles,by interacting with microorganisms,can fail the suitable functioning of biological systems in treatment *** this reason,research into the toxicity of ZnO is *** the present study,the toxicity mechanism of ZnO-NPs towards microbial communities central to granular activated sludge(GAS)performance was assessed over 120-day *** results demonstrate that the biotoxicity of ZnO-NPs is dependent upon its dosage,exposure time,and the extent of reactive oxygen species(ROS)***,GAS performance and the extracellular polymeric substances(EPS)content were significantly reduced at 50 mg/L *** exposure led to decreases in the activity of ammonia monooxygenase(25.2%)and nitrate reductase(11.9%)*** Field emission scanning electron microscopy images confirmed that ZnO-NPs were able to disrupt the cell membrane integrity and lead to cell/bacterial death via intracellular ROS generation which was confirmed by the Confocal Laser Scanning Microscopy *** exposure to the NPs,the bacterial community composition shifted to one dominated by Gram-positive *** results of this study could help to develop environmental standards and regulations for NPs applications and emissions.

关键词： Granular sludge Biotoxicity Reactive oxygen species Extracellular polymeric substances