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Neural Regeneration Research 2025年第10期20卷 2855-2861页

作者： Chanchal Sharma Sehwan kim Hyemi Eo Sang Ryong kim School of Life Science Kyungpook National UniversityDaeguKorea BK21 FOUR KNU Creative BioResearch Group Kyungpook National University DaeguKorea Brain Science and Engineering Institute Kyungpook National UniversityDaeguKorea

A critical unaddressed problem in Parkinson’s disease is the lack of therapy that slows or hampers *** medications effectively manage symptoms,they offer no long-term benefit because they fail to address the underlying neuronal *** highlights that the elusive goals of halting progression and restoring damaged neurons limit the long-term impact of current *** clinical trials using gene therapy have demonstrated the safety of various vector delivery systems,dosages,and transgenes expressed in the central nervous system,signifying tangible and substantial progress in applying gene therapy as a promising Parkinson’s disease ***,at diagnosis,many dopamine neurons remain in the substantia nigra,offering a potential window for recovery and *** propose that modulating these surviving dopamine neurons and axons in the substantia nigra and striatum using gene therapy offers a potentially more impactful therapeutic approach for future ***,innovative gene therapies that focus on preserving the remaining elements may have significant potential for enhancing long-term outcomes and the quality of life for patients with Parkinson’s *** this review,we provide a perspective on how gene therapy can protect vulnerable elements in the substantia nigra and striatum,offering a novel approach to addressing Parkinson’s disease at its core.

关键词： adeno-associated virus gene therapy neuroprotection neurorestoration neurotrophic factor nigrostriatal dopamine pathway pro-survival protein

Optimal Center-of-Mass Pivot Effect of Spinal Motion in Feline Galloping

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Journal of Bionic Engineering 2020年第5期17卷 970-977页

作者： Young Kook kim Dongwon yun LV R&D team Electro-technology R&D CenterLS ELECTRIC Co.LtdCheongju 28437South Korea Department of Robotics Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988South Korea

In this paper,we studied the acceleration behavior of a quadruped animal during a galloping *** the development of many quadruped robotic systems has been focused on dynamic movements,it is obvious that guidance from the dynamic behavior of quadruped animals is needed for robotics *** fulfill this demand,this paper deals with analysis of the galloping motions of a domestic cat,which is well known for its excellent acceleration performance among four-legged *** on the planar motion capture environment,the movement data of a galloping feline was acquired and the dynamic motions were estimated using a spring-mass *** particular,the effects of the position and angle of the center-of-mass of the cat,angular displacement of the spine,and angular velocity of the spine were analyzed and are discussed *** this process,it was possible to understand the dynamic movement characteristics of the cat,and to understand the relationships between,and the influences of,these *** this analysis,we provide significant data applicable to the design of joint movements in quadruped robot systems.

关键词： quadrupedalism feline galloping domestic cat center-of-mass

Yolk-shell-structured （***.s）9S8 solid-solution powders：Synthesis and application as anode materials for Na-ionbatteries

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Nano Research 2017年第9期10卷 3178-3188页

作者： Jung Hyun kim yun Chan Kang Department of Materials Science and Engineering Korea University Anam-Dong Seongbuk-Gu Seou1136-713 Republic of Korea

Multicomponent metal sulfide materials with a yolk–shell structure and a single phase were studied for the first time as anode materials for sodium-ion batteries. Yolk–shell-structured Fe–Ni–O powders with a molar ratio of iron and nickel components of 1/1 were prepared via one-pot spray pyrolysis. The prepared Fe–Ni–O powders were transformed into yolk–shell-structured (Fe0.5Ni0.5)9S8 solid-solution powders via a sulfidation process. The initial discharge and charge capacities of the (Fe0.5Ni0.5)9S8 powders at a current density of 1 A·g−1 were 601 and 504 mA·h·g−1, respectively. The discharge capacities of the (Fe0.5Ni0.5)9S8 powders for the 2nd and 100th cycle were 530 and 527 mA·h·g−1, respectively, and their corresponding capacity retention measured from the 2nd cycle was 99%. The (Fe0.5Ni0.5)9S8 powders had high initial discharge and charge capacities at a low current density of 0.1 A·g−1, and the reversible discharge capacity decreased slightly from 568 to 465 mA·h·g−1 as the current density increased from 0.1 to 5.0 A·g−1. The synergetic effect of the novel yolk–shell structure and the multicomponent sulfide composition of the (Fe0.5Ni0.5)9S8 powders resulted in excellent sodium-ion storage performance.

关键词： metal sulfide multicomponent sulfide yolk–shell sodium-ion batteries spray pyrolysis

RADIALLY SYMMETRIC SOLUTIONS FOR QUASILINEAR ELLIPTIC EQUATIONS INVOLVING NONHOMOGENEOUS OPERATORS IN AN ORLICZ-SOBOLEV SPACE SETTING

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Acta Mathematica Scientia 2020年第6期40卷 1679-1699页

作者： Jae-Myoung kim yun-Ho kim Jongrak LEE Department of Mathematics Education Andong National UniversityAndong 36729Republic of Korea Department of Mathematics Education Sangmyung UniversitySeoul 03016Republic of Korea Department of Mathematics Jeju National UniversityJeju 63243Republic of Korea

We investigate the following elliptic equations:⎧⎩⎨−M(∫R Nϕ(|∇u|2)dx)div(ϕ′(|∇u|2)∇u)+|u|α−2 u=λh(x,u),u(x)→0,as|x|→∞,in R N,where N≥2,1 详细信息

We investigate the following elliptic equations:⎧⎩⎨−M(∫R Nϕ(|∇u|2)dx)div(ϕ′(|∇u|2)∇u)+|u|α−2 u=λh(x,u),u(x)→0,as|x|→∞,in R N,where N≥2,1

关键词： radial solution quasilinear elliptic equations variational methods Orlicz-Sobolev spaces

Fabrication of Piezoelectric Cellulose Paper and Audio Application

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Journal of Bionic Engineering 2009年第1期6卷 18-21页

作者： Jung-Hwan kim Sungryul yun Joo-Hyung kim Jaehwan kim Creative Research Center for EAPap Actuator Department of Mechanical EngineeringINHA University253 Young-Hyun DongNam GuIncheon402-751Republic of Korea

We report the fabrication process of piezoelectric cellulose paper and the enhancement method of its piezoelectric property. Stretching method with different wet-drawing ratios was introduced to increase the piezoelectric property of cellulose paper during regeneration *** is observed that the Young's modulus and the piezoelectric charge constants are very dependent on the drawing ratio and the direction of nanofibrils of piezoelectric *** the enhanced piezoelectric property,we prove that the flexible regenerated piezoelectric cellulose can be applied to the potential acoustic applications such as thin piezoelectric paper speaker.

关键词： piezoelectric speaker piezoelectricity cellulose wet-drawing process

Polymer donors with hydrophilic side-chains enabling efficient and thermally-stable polymer solar cells by non-halogenated solvent processing

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Nano Research Energy 2024年第1期3卷 19-29页

作者： Soodeok Seo Jun-Young Park Jin Su Park Seungjin Lee Do-Yeong Choi yun-hi kim Bumjoon J.kim Department of Chemical and Biomolecular Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Department of Materials Engineering and Convergence Technology and ERI Gyeongsang National UniversityJinju 52828Republic of Korea Advanced Energy Materials Research Center Korea Research Institute of Chemical Technology(KRICT)Daejeon 34114Republic of Korea Department of Chemistry and ERI Gyeongsang National UniversityJinju 52828Republic of Korea

Polymer solar cells(PSCs)with high power conversion efficiency(PCE)and environment-friendly fabrication are the main requirements enabling their production in industrial *** the use of non-halogenated solvent processing is inevitable for the PSC fabrication,it significantly reduces the processability of polymer donors(PDS)and small-molecule acceptors(SMAs).This often results in unoptimized blend morphology and limits the device *** address this issue,hydrophilic oligoethylene glycol(OEG)side-chains are introduced into a PD(2EG)to enhance the molecular compatibility between the PD and L8-BO *** 2EG PD induces higher crystallinity and alleviates phase separation with the SMA compared to the reference PD(PM7)with hydrocarbon ***,the 2EG-based PSCs exhibit a higher PCE(15.8%)than the PM7-based PSCs(PCE=14.4%)in the ortho-xylene based ***,benefitted from the reduced phase separation and increased crystallinity of 2EG PDS,the 2EG-based PSCs show enhanced thermal stability(84%of initial PCE after 120 h heating)compared to that of the PM7-based PSCs(60%of initial PCE after 120 h heating).This study demonstrates the potential of OEG side-chain-incorporated materials in developing efficient,stable,and eco-friendly PSCs.

关键词： polymer solar cell polymer donor OEG side-chain non-halogenated solvent process side-chain engineering

Methodology for predicting the life of plasma-sprayed thermal barrier coating system considering oxidation-induced damage

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Journal of Materials Science & Technology 2022年第10期105卷 45-56页

作者： Keekeun kim Damhyun kim Kibum Park Junghan yun Chang-Sung Seok School of Mechanical Engineering Sungkyunkwan UniversitySuwonGyeonggi 440-746Korea

The lifespan of plasma-sprayed thermal barrier coating(TBC)systems is difficult to predict owing to the variety of microstructures and deterioration *** this study,we developed a novel TBC damage model to reflect deterioration histories;thus,it can be applied to various *** to TBCs is classifed into oxidation and mechanical damage;therefore,a detailed deterioration history can be *** addition,by introducing a virtual S–N diagram,a life prediction model that can be applied to TBCs with various microstructures was *** used the proposed damage and life prediction models in isothermal aging and thermal cycle tests with different aging *** predicted lifespan of TBCs by using the proposed models was within 95%of the results obtained by performing actual tests in the temperature range of 1150–1350℃.

关键词： Thermal barrier coatings Damage model Temperature history Thermal fatigue Life prediction model

Implementation of configuration dependent stiffness proportional damping for the dynamics of rigid multi-block systems

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Earthquake Engineering and Engineering Vibration 2003年第1期2卷 87-98页

作者： yun Byeong Chae Jae Kwan kim R & D Division Chungsuk Engineering57Garak-dongSongpa-kuSeoul138-802Korea Assistant Engineer School of Civil Urban and Geosystem EngineeringSeoul National UniversitySeoul151-742Korea Associate Professor

The distinct element method(DEM)has been used successfully for the dynamic analysis of rigid block sys- *** of many difficulties associated with DEM is modeling of *** this paper,new procedures are proposed for the damping modeling and its numerical implementation in distinct element analysis of rigid muhi-block *** stiff- ness proportional damping is constructed for the prescribed damping ratio,based on the non-zero fundamental frequency ef- fective during the time interval while the boundary conditions remain essentially *** this time interval,the funda- mental frequency can be estimated without complete eigenvalue *** damping coefficients will vary while the damp- ing ratio remains the same throughout the entire analysis.A new numerical procedure is developed to prevent unnecessary energy loss that can occur during the separation *** procedures were implemented in the development of the dis- tinet element method for the dynamic analyses of piled multi-block *** analysis results |or the single-block and two-block systems were in a good agreement with the analytic *** to the seismic analyses of piled four- block systems revealed that the new procedures can make a significant difference and may lead to much-improved results.

关键词： multi-block systems stiffness proportional damping rocking impact distinet element method rigid body dynamics

Nanowatt power operation of silicon nanowire NAND logic gates on bendable substrates

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Nano Research 2016年第12期9卷 3656-3662页

作者： Junggwon yun Myeongwon Lee Youngin Jeon Minsuk kim Yoonjoong kim Doohyeok Lim Sangsig kim Department of Electrical Engineering Korea University 145 Anam-ro Seongbuk-gu Seoul 02841 Republic of Korea

In this paper, we propose a novel construction of silicon nanowire （SiNW） negative-AND （NAND） logic gates on bendable plastic substrates and describe their electrical characteristics. The NAND logic gates with SiNW channels are capable of operating with a supply voltage as low as 0.8 V, with switching and standby power consumption of approximately 1.1 and 0.068 nW, respectively. Superior electrical characteristics of each SiNW transistor, including steep subthreshold slopes, high Ion/off ratio, and symmetrical threshold voltages, are the major factors that enable nanowatt-range power operation of the logic gates. Moreover, the mechanical bendability of the logic gates indicates that they have good and stable fatigue properties.

关键词： negative-AND (NAND)logic gates bendable electronics silicon nanowires nanowatt operation