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Journal of Environmental Science and Engineering(B) 2021年第4期10卷 151-156页

作者： Chanthin Ouk kim eang tho Sophoanrith Ro Samraksa Seang Theary Leng Penghaing Ly Division of Research and Extension Royal University of AgriculturePhnom Penh 120501Cambodia Faculty of Agronomy Royal University of AgriculturePhnom Penh 120501Cambodia

This research was carried out to assess the effect of different varieties and mulching types on insect and disease infestation,and the yield of *** experiment was conducted in Sangkat TuekVil,KrongSiem Reap,in Cambodia.A 2×4 factorial in RCBD(Randomized Complete Blocks Design)was used to layout the trial,in which two varieties(Texas Early Grano 502 PRR and Earth F1)and four mulch types(non-mulch,rice Straw,silver plastic mulching and black plastic mulching)were used as the *** of these treatments was to enhance soil temperature,leaf number plant-1,stand count,bulb diameter,single bulb weight,insect incidence,disease incidence and bulb yield are different to all *** the result,the bulb yields of onions among these treatments were found superior in Texas Early Grano 502 PRR combined with Black Plastic mulch followed by Texas Early Grano 502 PRR combined with silver plastic mulch and Texas Early Grano 502 PRR combined rice straw mulch,whereas the lowest was found in Earth F1combined with non-mulch.

关键词： Onion(Allium cepa L.) mulching infestation disease insect and yield

Evaluation of Selected Chemical,Biological Fungicides,and Induced Resistance to Control White Rot(Sclerotium rolfsii Sacc.)on Tomato

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Journal of Environmental Science and Engineering(A) 2022年第2期11卷 62-69页

作者： Penghaing Ly kim eang tho RabyNget Socheath Ong Chanthin Ouk Savry Poeng Phanta Seng Theary Leng Socheat Chheum Division of Research and Extension Royal University of AgriculturePhnom Penh 120501Cambodia Faculty of Agronomy Royal University of AgriculturePhnom Penh 120501Cambodia

Tomato(Solanum lycopersicum)is one of the most widely grown and consumed as fresh vegetable in the *** rolfsii *** one of the most destructive diseases and affects more than 500 plant *** study was conducted for“Evaluation of Selected Chemical,Biological Fungicides,and Induced Resistant to Control White Rot(Sclerotium rolfsii Sacc.)on Tomato”.The experiment was conducted at the Royal University of Agriculture and divided into two *** first section conducted under in vitro condition consists of four treatments T1 control treatment,T2 copper hydroxide,T3 azoxystrobin+difenoconazole,T4 metalaxyl+mancozeb in Nagoya Laboratory,and had been starting from 11st May to 15th May *** two was conducted in a pot in net-house which started from 1st January 2019 to 19th February 2019 and 1st January to 19th February 2020 and arranged in RCBD(Randomized Completely Block Design)with six replications and nine treatments.T0 negative control,T1 inoculate but not treatment,T2 metalaxyl+mancozeb,T3 azoxystrobin+difenoconazole,T4 copper hydroxide,T5 acibenzolar-S-methyl,T6 chicken dung+Trichoderma harzianum,T7 acibenzolar-S-methyl+chicken dung+Trichoderma harzianum,T8 acibenzolar-S-methyl+metalaxyl+*** were collected on colonizing diameter in *** pot experiment collected on disease incidence,incubation period Based on the result under in vitro condition metalaxyl+mancozeb highly inhibited germination of Sclerotium rolfsii when compared with another ***,the application of copper hydroxide seems less effective compared with *** in pot experiment,when treated after symptom of southern blight appeared to seem less effective on the severity of southern *** contrast,when applied as a protectant and curative when symptoms appeared only systemic fungicide azoxystrobin+difenoconazole significantly reduced the severity of Sclerotium rolfsii and delayed incubation period while compared with other treatments(p<0.0

关键词： Sclerotium rolfsii Sacc. biological control Trichoderma hazianum induced resistance chemical control

吡喹酮对鲤鱼感染台湾棘带吸虫后期囊幼虫的防治效果

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南方农业学报 2012年第4期43卷 520-523页

作者： kim Van Van Truong Dinh Hoai Kurt Buchmann Anders Dalgaard Nguyen Van tho 河内农业大学动物水产科技系水产研究室越南河内哥本哈根大学生命科学学院兽医疾病生物系丹麦哥本哈根河内农业大学兽医畜养系越南河内

【目的】探讨3种不同药物处理方式对台湾棘带吸虫引起的鲤鱼幼鱼急性鱼鳃传染病(开放性鳃病)的防治效果。【方法】在试验初期,将1620条鲤鱼幼鱼(70日龄)鱼鳃自然感染台湾棘带吸虫,随后分成4组,分别采用CuSO4、福尔马林和吡喹酮不同方式... 详细信息

【目的】探讨3种不同药物处理方式对台湾棘带吸虫引起的鲤鱼幼鱼急性鱼鳃传染病(开放性鳃病)的防治效果。【方法】在试验初期,将1620条鲤鱼幼鱼(70日龄)鱼鳃自然感染台湾棘带吸虫,随后分成4组,分别采用CuSO4、福尔马林和吡喹酮不同方式处理6周,与对照(自然喂食、不使用任何化学药剂)比较防治鲤鱼幼鱼急性鳃传染病的效果。【结果】感染台湾棘带吸虫的幼鱼生长缓慢,其身长和体重增长均较慢。施药后,幼鱼台湾棘带吸虫后期囊幼虫感染强度减少。在每千克饲料中分别添加50和75mg吡喹酮喂食幼鱼5d,可以杀死鱼鳃中所有的台湾棘带吸虫后期囊幼虫,且鱼鳃恢复正常;而使用25mg吡喹酮,仅有35%的后期囊幼虫死亡。所有不同浓度CuSO4处理(0.3、0.4和0.5mg/kg冲洗浸泡24h及以3.0、4.0和5.0mg/kg冲洗浸泡10m)和福尔马林处理(20、25和30mg/kg冲洗浸泡及200、250和300mg/kg短时间冲洗浸泡)均不能杀死台湾棘带吸虫后期囊幼虫。【结论】经普通化学药剂CuSO4或福尔马林冲洗浸泡,不能防治由台湾棘带吸虫后期囊幼虫引起的鲤鱼开放性鳃病,但50～75mg吡喹酮/kg饲料可以在5d内治疗该病。

关键词：鲤鱼台湾棘带吸虫后期囊幼虫吡喹酮越南

Efficacy of cap-assisted colonoscopy according to lesion location and endoscopist training level

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World Journal of Gastroenterology 2015年第20期21卷 6261-6270页

作者： Dong Jun kim Hyung Wook kim Su Bum Park Dae Hwan Kang Cheol Woong Choi Joung Boom Hong Byoung Hoon Ji Chang Seok Lee Department of Internal Medicine Medical Research InstitutePusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology Pusan National University Yangsan Hospital Department of Internal Medicine Dong-eui Medical Center Department of Internal Medicine Bongseng Memorial Hospital

AIM: To evaluate the efficacy of cap-assisted colonoscopy(CAC) for detection of colorectal polyps and adenomas according to the lesion location and endoscopist training ***: Patients 20 years or older, who underwent their first screening colonoscopy in a single tertiary center from May 2011 to December 2012 were enrolled in this study. All patients underwent either CAC or standard colonoscopy(SC), and all of the procedures were performed by 11 endoscopists(8 trainees and 3 experts). All procedures were performed with highdefinition colonoscopes and narrow band imaging. The eight trainees had experiences of performing 150 to 500 colonoscopies, and the three experts had experiences of performing more than 3000 colonoscopies. A 4-mmlong transparent cap was attached to the end of a colonoscope in the CAC group. We retrospectively evaluated the number of polyps and adenomas, polyp detection rate(PDR), and the number of adenomas and adenoma detection rate(ADR) according to the lesion location and endoscopist training level between CAC and SC. We also evaluated the number of polyps and adenomas according to their size between CAC and ***: Overall, PDR and ADR using CAC were significantly higher than those using SC for both whole colon(48.5% vs 40.7%, P = 0.012; 35.7% vs 28.3%, P = 0.012) and right-side colon(35.3% vs 26.6%, P = 0.002; 27.0% vs 16.9%, P those using SC for both the whole colon(46.7% vs 39.7%, P = 0.040; 33.9% vs 26.0%, P =0.012) and right-side colon(34.2% vs 26.5%, P = 0.015; 25.3% vs 15.9%, P = 0.001). In the expert group, the PDR and ADR using CAC were si

关键词： Colonoscopy Cap-assisted colonoscopy Colonic polyps Adenoma Colorectal neoplasm

Detection of decline in estimated glomerular filtration rate in patients with type 2 diabetes by cystatin C-based equations

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World Journal of Nephrology 2024年第4期13卷 103-116页

作者： Tam Thai Thanh Tran Tien kim Ha Nhut Minh Phan Minh Van Le Tin Hoang Nguyen Department of Physiology Faculty of MedicineCan Tho University of Medicine and PharmacyCan Tho 900000Viet Nam Department of Functional Exploration Can Tho University of Medicine and Pharmacy HospitalCan Tho 900000Viet Nam School of Medicine and Pharmacy The University of Da NangDa Nang 550000Viet Nam Faculty of Medicine Can Tho University of Medicine and PharmacyCan Tho 900000Viet Nam

BACKGROUND Aging population is a significant issue in Viet Nam and across the *** individuals are at higher risk of chronic kidney disease(CKD),especially those with *** studies found that the estimated glomerular filtration rate(eGFR)determined using creatinine-based equations was not as accurate as that determined using cystatin C-based *** C-based equations may be beneficial in elderly patients with an age-associated decline in kidney *** determination of eGFR decline and associated factors would aid in appropriate interventions to improve kidney function in elderly patients with *** To determine the utility of cystatin C-based equations in early detection of eGFR decline and to explore factors associated with eGFR decline in elderly patients with *** This cross-sectional study included 93 participants aged≥60 years evaluated in Can tho University of Medicine and Pharmacy Hospital between October 2022 and July 2023,including 47 and 46 participants with and without diabetes respectively,according to the American Diabetes Association criteria for *** kappa coefficient,Student’s t,Mann-Whitney,χ2,Pearson’s correlation,multivariate logistic regression,and multiple linear regression analyses were *** The eGFRs were lower with the cystatin C-based equations than with the creatinine-based *** agreement was found between the Modification of Diet in Renal Disease(MDRD)and CKD Epidemiology Collaboration(CKD-EPI)2021 creatinine-cystatin C equations(kappa=0.66).In the diabetes group,30%of the participants had low *** plasma glucose and glycated hemoglobin were associated with an increased risk of eGFR decline(P<0.05)and negatively correlated with eGFR(P=0.001).By multivariate logistic regression,total cholesterol,and exercise were independently associated with low *** multiple linear regression,higher plasma glucose levels were correlated with lower eGFR(P=0.026,

关键词： Cystatin C Estimated glomerular filtration rate Elderly Diabetes Nephrology Kidney function

钛颗粒对大鼠成骨细胞影响的mRNA差异显示研究

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中华外科杂志 2001年第1期39卷 72-75页

作者：马庆军党耕町 H Takei J kim KL Paul Sung 北京大学第三临床医院骨科 100083 美国加州大学圣迭戈分校

目的　观察钛金属颗粒对大鼠成骨细胞基因表达的影响 ,寻找与假体周围骨溶解有关的新基因。　方法　在含 10 %牛血清的DMEM培养基中培养Wistar幼鼠成骨细胞 ,达 80 %丰满后加入 0 .1%钛颗粒 ,再培养 2 4h后收获细胞并提取总RNA。用mRNA... 详细信息

目的　观察钛金属颗粒对大鼠成骨细胞基因表达的影响 ,寻找与假体周围骨溶解有关的新基因。　方法　在含 10 %牛血清的DMEM培养基中培养Wistar幼鼠成骨细胞 ,达 80 %丰满后加入 0 .1%钛颗粒 ,再培养 2 4h后收获细胞并提取总RNA。用mRNA差异显示技术比较处理组与对照组之间在mRNA表达上的差别。将有差别的表达带回收、扩增、克隆化 ,用于ReverseNorthern杂交、Northern杂交及测序 ,将测序结果与NCBI数据库比较。　结果　在处理与对照间找到 35条差异表达带 ,经ReverseNorthern杂交得到 5个阳性克隆 ,经测序及NCBI数据库分析 ,其中被命名为G46T的基因与单核细胞趋化蛋白 3达 92 %同源 ,另外 4个是新基因。　结论　钛颗粒可引起鼠成骨细胞基因表达的变化 ;G46T基因可能与假体周围骨溶解有关。

关键词：成骨细胞差异显示钛金属颗粒大鼠关节假体 MRNA

Effect of Combined Vitamin C and Vitamin E Supplementation on Reproductive Performance and Hatching Rate in Japanese Laying Quail

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Journal of Environmental Science and Engineering(B) 2022年第4期11卷 139-144页

作者： Nguyen Thi kim Khang Duong Van Toi Ngo Thi Minh Suong Masashi Takahashi Department of Animal Sciences College of AgricultureCan Tho UniversityCan Tho City 94156Vietnam Department of Animal Science Hokkaido UniversityHokkaido 060-8589Japan

This study was carried out to evaluate the effect of vitE(Vitamin E)supplementation in combination with vitC(Vitamin C)on reproductive performance and hatching rate of Japanese quail at the age of 59-114 days.A total of 132 laying quails were arranged in a completely randomized design with 3 treatments and 4 replicates,each replicate being 9 female quails and 2 male quails at 59 days of *** experimental treatments were as follows:control fed the basal diet(KPCS),E125C75 including KPCS supplemented with 125 mg vitE/kg feed combined with 75 mg vitC/kg feed and E125C125 including KPCS supplemented 125 mg vitE/kg feed combined with 125 mg vitC/kg *** results showed that the highest WG(Weight Gain)was in E125C125(30.32 g)and lowest in E125C75(17.37 g).There were no statistically significant differences between treatments in terms of laying rate,feed conversion ratio,egg mass and egg ***,hatching rate and bodyweight of quails at 1 day of age were significantly different between treatments,the highest was E125C125(74.37%and 7.43 g),followed by E125C75(70.02%and 7.03 g)and the lowest was control(65.89%and 6.82 g).It can be concluded that E125C125 not only improved laying rate but also increased hatching rate and bodyweight of quail chick.

关键词： Laying rate hatchability BW(Body Weight) quail

A novel IRAK4/PIM1 inhibitor ameliorates rheumatoid arthritis and lymphoid malignancy by blocking the TLR/MYD88-mediated NF-κB pathway

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Acta Pharmaceutica Sinica B 2023年第3期13卷 1093-1109页

作者： Sae-Bom Yoon Hyowon Hong Hee-Jong Lim Ji Hye Choi Yoon Pyo Choi Seong Wook Seo Hyuk Woo Lee Chong Hak Chae Woo-Kyu Park Hyun Young kim Daeyoung Jeong Tran Quang De Chang-Seon Myung Heeyeong Cho Therapeutics&Biotechnology Division Korea Research Institute of Chemical TechnologyYuseong-guDaejeon 34114Republic of Korea Department of Pharmacology Chungnam National University College of PharmacyYuseong-guDaejeon 34134Republic of Korea Future Medicine Co. Ltd.Rm616 LH-Business Growth CenterSeongnamGyeonggido 13449Republic of Korea Department of Chemistry College of Natural SciencesCan Tho UniversityCan Tho city 9000Viet Nam

Interleukin-1 receptor-associated kinase 4(IRAK4)is a pivotal enzyme in the Toll-like receptor(TLR)/MYD88 dependent signaling pathway,which is highly activated in rheumatoid arthritis tissues and activated B cell-like diffuse large B-cell lymphoma(ABC-DLBCL).Inflammatory responses followed by IRAK4 activation promote B-cell proliferation and aggressiveness of ***,proviral integration site for Moloney murine leukemia virus 1(PIM1)functions as an anti-apoptotic kinase in propagation of ABC-DLBCL with ibrutinib *** developed a dual IRAK4/PIM1 inhibitor KIC-0101 that potently suppresses the NF-κB pathway and proinflammatory cytokine induction in vitro and in *** rheumatoid arthritis mouse models,treatment with KIC-0101 significantly ameliorated cartilage damage and ***-0101 inhibited the nuclear translocation of NF-κB and activation of JAK/STAT pathway in *** addition,KIC-0101 exhibited an anti-tumor effect on ibrutinib-resistant cells by synergistic dual suppression of TLR/MYD88-mediated NF-κB pathway and PIM1 *** results suggest that KIC-0101 is a promising drug candidate for autoimmune diseases and ibrutinib-resistant B-cell lymphomas.

关键词： Drug discovery IRAK4 PIM1 NF-κB pathway Rheumatoid arthritis ABC-DLBCL Ibrutinib resistance Dual inhibitor

奉祀天后圣母的研究--以越南芹苴市华人的天后圣母信仰为例

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妈祖文化研究 2024年第1期 25-33页

作者： [越南]阮福才陈氏金黄 FPT大学越南芹苴26132 坚江师范学院越南坚江83000

本文以芹苴市华人奉祀天后圣母为研究对象,探讨了这一文化的特征、形成原因和社会意义,分析了芹苴市华人奉祀天后圣母的组成要素、内在逻辑和外在表现发现,这一文化是华人社区对中国传统文化的继承和创新,也是对越南多元文化的融入和贡... 详细信息

本文以芹苴市华人奉祀天后圣母为研究对象,探讨了这一文化的特征、形成原因和社会意义,分析了芹苴市华人奉祀天后圣母的组成要素、内在逻辑和外在表现发现,这一文化是华人社区对中国传统文化的继承和创新,也是对越南多元文化的融入和贡献。本文认为,芹苴市华人奉祀天后圣母是华人社会意识的反映,也是华人社会实践的指导,体现了华人对生存环境的适应和改造。同时指出,天后圣母的当地信仰满足了华人的精神需求,增强了华人的社会凝聚力,促进了华人与越南社会的和谐共处。

关键词：越南华人妈祖文化跨文化交流