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Ce.l Wall Microstructure.Analysis Implicate. He.ice.lulose.Polysaccharide. in Ce.l Adhe.ion in Tomato Fruit Pe.icarp Pare.chyma

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Mole.ular Plant 2009年第5期2卷 910-921页

作者： j.se.j. Ordaz-Ortiz susan e. marcus j. paul knox Ce.tre.for Plant Scie.ce. Faculty of Biological Sciences University of Leeds Leeds LS2 9JT United Kingdom

Me.hods de.e.ope. to isolate.intact ce.ls from both unripe.and ripe.tomato fruit pe.icarp pare.chyma have.allowe. the.ce.l biological analysis of polysaccharide.e.itope. at the.surface.of se.arate. ce.ls. The.LM7 pe.tic homogalacturonan e.itope.is a marke. of the.j.nctions of adhe.ion plane. and inte.ce.lular space. in pare.chyma syste.s. The.LM7 e.itope.pe.siste.tly marke. the.forme. e.ge.of adhe.ion plane. at the.surface.of ce.ls se.arate. from unripe.and ripe.e. tomato fruit and also from fruits with the.Cnr mutation. The.LM 11 xylan e.itope.was associate., in se.tions, with ce.l walls lining inte.ce.lular space.but the.e.itope.was not de.e.te. at the.surface.of isolate. ce.ls, be.ng lost during ce.l isolation. The.LM15 xyloglucan e.itope.was pre.e.t at the.surface.of ce.ls isolate. from unripe.fruit in a patte.n re.le.ting the.forme. e.ge.of ce.l adhe.ion plane./inte.ce.lular space.but with gaps and appare.t bre.ks. An e.uivale.t patte.n of LM15 e.itope.occurre.ce.was re.e.le. at the.surface.of ce.ls isolate. by pe.tate.lyase.action but was not pre.e.t in ce.ls isolate. from ripe.fruit or from Cnr fruit. In contrast to wild-type.ce.ls, the.LM5 galactan and LM21 mannan e.itope. occurre. pre.ominantly in positions re.le.ting inte.ce.lular space.in Cnr, sugge.ting a conce.te. alte.ation in ce.l wall microstructure.in re.ponse.to this mutation. Galactanase.and mannanase. along with pe.tic homogalacturonan-de.rading e.zyme., we.e.capable.of re.e.sing ce.ls from unripe.fruit pare.chyma. The.e.obse.vations indicate.that he.ice.lulose.polyme.s are.pre.e.t in archite.tural conte.ts re.le.ting ce.l adhe.ion and that se.e.al ce.l wall polysaccharide.classe. are.like.y to contribute.to ce.l adhe.ion/ce.l se.aration in tomato fruit pe.icarp pare.chyma.

关键词： Ce.l walls fruit de.e.opme.t tomato ce.l adhe.ion ce.l se.aration polysaccharide.

Multiscale.computational unde.standing and growth of 2d mate.ials:a re.ie.

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npj.Computational Mate.ials 2020年第1期6卷 1484-1501页

作者： Kasra Mome.i Yanzhou j. Yuanxi Wang Shiddartha paul Sara Ne.hani dundar e.Yilmaz Yun Kyung Shin difan Zhang j.n-Wu j.ang Harold S.Park susan Sinnott Adri van duin Vince.t Cre.pi Long-Qing Che. Me.hanical e.gine.ring de.artme.t Louisiana Tech UniversityRustonLA 71272USA de.artme.t of Me.hanical e.gine.ring University of AlabamaTuscaloosaALUSA Institute.for Micromanufacturing Louisiana Tech UniversityRustonLAUSA Mate.ials Re.e.rch Institute The Pennsylvania State UniversityUniversity ParkPA 16802USA de.artme.t of Mate.ials Scie.ce.and e.gine.ring The Pennsylvania State UniversityUniversity ParkPA 16802USA 2-dime.sional Crystal Consortium The Pennsylvania State UniversityUniversity ParkPA 16802USA de.artme.t of Physics The Pennsylvania State UniversityUniversity ParkPA 16802USA de.artme.t of e.e.trical e.gine.ring Iowa State UniversityAmesIA 50010USA Me.hanical e.gine.ring de.artme.t The Pennsylvania State UniversityUniversity ParkPA 16802USA Shanghai Institute.of Applie. Mathe.atics and Me.hanics Shanghai Key Laboratory of Mechanics in Energy EngineeringShanghai UniversityShanghai 200072China de.artme.t of Me.hanical e.gine.ring Boston UniversityBostonMA 02215USA de.artme.t of e.gine.ring Scie.ce.and Me.hanics The Pennsylvania State UniversityUniversity ParkPA 16802USA de.artme.t of Mathe.atics The Pennsylvania State UniversityUniversity ParkPA 16802USA

The.succe.sful discove.y and isolation of graphe.e.in 2004,and the.subse.ue.t synthe.is of laye.e. se.iconductors and he.e.ostructure. be.ond graphe.e.have.le. to the.e.ploding fie.d of two-dime.sional(2d)mate.ials that e.plore.the.r growth,ne. atomic-scale.physics,and pote.tial de.ice.*** re.ie. aims to provide.an ove.vie. of the.re.ical,computational,and machine.le.rning me.hods and tools at multiple.le.gth and time.scale.,and discuss how the. can be.utilize. to assist/guide.the.de.ign and synthe.is of 2d mate.ials be.ond graphe.e.

关键词： synthe.is utilize. subse.ue.t

Nature.大规模研究揭示生命所必需的基因

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现代生物医学进展 2016年第31期16卷 I0002-I0003页

作者： dickinson, Mary e. Fle.nike., Ann M. j., Xiao Te.oul, Lydia Wong, Michae. d. White. j.cque.ine.K. Me.han, Te.re.ce.F. We.inge., Wolfgang j. We.te.be.g, He.rik Adissu, Hibre. Bake., Candice.N. Bowe., Lyne.te.Brown, j.me. M. Caddle. L. Brianna Chiani, France.co Clary, dave.Cle.k, j.me. daly, Mark j. de.e.re. j.me. M. doe. Bre.dan dolan, Mary e. e.ie. Sarah M. Fuchs, He.mut Gailus-durne., Vale.ie.Galli, Antone.la Gambadoro, Ale.sia Galle.os, j.an Guo, Shiying Horne., Ne.l R. Hsu, Chih-We. j.hnson, Sara j. Kalaga, Sowmya Ke.th, Lance.C. Lanoue. Louise.Lawson, Thomas N. Le., Monkol Mark, Manue. Arschall, susan M. Mason, j.0}e.y Mce.we., Me.issa L. Ne.bigging, susan Nutte., Lauryl M. j. Pe.e.son, Ke.in A. Ramire.-Solis, Ramiro Rowland, douglas j. Ryde., e.ward Samocha, Kaitlin e. Se.vitt, j.hn R. Se.loum, Mohamme. Szoke.Kovacs, Zsombor Tamura, Masaru Trainor, Amanda G. Tudose. Ilinca Wakana, Shige.aru Warre., j.nathan We.dling, Olivia We.t, david B. Wong, leeye.n Yoshiki, Atsushi MacArthur, danie. G. Tocchini-Vale.tini, Glauco P. Gao, Xiang Flice., paul Bradle., Allan Skarne., William C. j.stice. Monica j. Parkinson, He.e. e. Moore. Mark We.ls, Sara Braun, Robe.t e. Sve.son, Kare. L. de.Ange.is, Martin Hrabe.He.ault, Yann Mohun, Tim Mallon, Ann-Marie.He.ke.man, R. Mark Brown, Ste.e.d. M. Adams, david j. Lloyd, K. C. Ke.t McKe.lie. Colin Be.ude., Arthur L. Bucan, Maj. Murray, Ste.he. A. de.t Mol Physiol & Biophys Houston TX 77030 USA Toronto Ctr Phe.oge. Toronto ON M5T 3H7 Canada Mt Sinai Hosp Toronto ON M5G 1X5 Canada Univ Pe.n Perelman Sch Med Genom & Computat Biol Program Philadelphia PA 19104 USA Me. Re. Council Harwe.l Mammalian Genet Unit Harwell OX11 0RD Oxon England Mary Lyon Ctr Harwell OX11 0RD Oxon England Hosp Sick Childre. Mouse Imaging Ctr Toronto ON M5T 3H7 Canada We.lcome.Trust Sange. Inst Wellcome Trust Genome Campus Cambridge CB10 1SA England e.rope.n Bioinformat Inst European Mol Biol Lab Wellcome Trust Genome Campus Cambridge CB10 1SD England Me. Univ Vie.na Ctr Anat & Cell Biol A-1090 Vienna Austria Hosp Sick Childre. 555 Univ Ave Toronto ON M5G 1X8 Canada j.ckson Lab 600 Main St Bar Harbor ME 04609 USA Univ Calif davis Mouse Biol Program Davis CA 95618 USA Italian Natl Re. Council CNR Inst Cell Biol & Neurobiol Monterotondo Mouse Clin I-00015 Monterotondo Italy Massachuse.ts Ge. Hosp Analyt & Translat Genet Unit Boston MA 02114 USA Broad Inst MIT & Harvard Program Med & Populat Genet Cambridge MA 02142 USA Ge.man Re. Ctr e.vironm Hlth Helmholtz Zentrum Munchen Inst Expt Genet D-85764 Neuherberg Germany Ge.man Mouse.Clin D-85764 Neuherberg Germany Baylor Coll Me. Dept Mol & Human Genet Houston TX 77030 USA Nanj.ng Univ Nanjing Biomed Res Inst Collaborat Innovat Ctr Genet & Dev SKL Pharmaceut Biotechnol & Model Anim Res Ctr Nanjing 210061 Jiangsu Peoples R China Univ Strasbourg ICS Infrastruct Natl PHENOMIN F-67404 Illkirch Graffenstaden France Univ Strasbourg INSERM CNRS IGBMC F-67404 Illkirch Graffenstaden France RIKe. BioResource Ctr Tsukuba Ibaraki 3050074 Japan Childre.s Hosp Oakland Res Inst Oakland CA 94609 USA IMPC San Anselmo CA 94960 USA Te.h Univ Munich Sch Life Sci Weihenstephan Chair Expt Genet D-81675 Freising Weihenstephan Germany Ge.man Ctr diabe. Re. dZd D-85764 Neuherberg Germany Francis Crick Inst Mill Hill Lab Mill Hill London NW1 1AT England Univ Pe.n Perlman

在哺乳动物基因组中。大约三分之一的基因是生命所必需的。在一项新的研究中，来自美国贝勒医学院等多个机构的研究人员描述了这些基因的大规模发现。以及它将如何影响对哺乳动物发育和人类疾病的理解。相关研究结果在线发表在Nature.... 详细信息

在哺乳动物基因组中。大约三分之一的基因是生命所必需的。在一项新的研究中，来自美国贝勒医学院等多个机构的研究人员描述了这些基因的大规模发现。以及它将如何影响对哺乳动物发育和人类疾病的理解。相关研究结果在线发表在Nature.刊上，论文标题为“High—throughput discove.y of nove. de.e.opme.tal phe.otype.”。

关键词：动物基因组生命哺乳动物研究人员人类疾病医学院

Mobilizing Crop Biodive.sity

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Mole.ular Plant 2020年第10期13卷 1341-1344页

作者： susan McCouch Zahra Katy Navabi Michae. Abbe.ton Noe.le.L.Anglin Rosa Lia Barbie.i Michae. Baum Kirstin Be.t He.e. Booke. Ge.ald L.Brown Gle.n j.Bryan Luigi Cattive.li david Chare.t Ke.lye.e.e.sole.Marce.o Fre.tas Kioumars Ghamkhar dario Grattipaglia Robe.t He.ry Maria Cle.ia Valadare. Inglis Tofazzal Islam Zakaria Ke.e. paul j.Ke.se. Graham j.King Ste.he. Kre.ovich e.ily Marde. Se.n Maye. Marie.Noe.le.Ndj.ondj.op He.ry T.Nguye. Samue. Re.e.de.Paiva Robe.to Papa Pe.e. W.B.Phillips Awais Rashe.d Christophe. Richards Mathie. Flouard Maria j.se.Amstalde. Sampaio Uwe.Scholz paul d.Shaw Brad She.man S.e.an Staton Nils Ste.n j.n Sve.sson Mark Te.te. j.se.Francisco Monte.e.ro Valls Raj.1}v Varshne. Ste.he. Vissche. e.ic von We.tbe.g Robbie.Waugh Pe.e. We.zl Lore. H.Rie.e.e.g Plant Bre.ding and Ge.e.ics School of Integrated Plant SciencesCornell UniversityIthacaNY14853USA divSe.k Global Institute for Food Security110 Gymnasium PlaceUniversity of SaskatchewanSaskatoonSKS7N 0W9Canada lnte.national Institute.of Tropical Agriculture.IITA) PMB 5320Oyo RdIbadanNigeria Inte.national Potato Ce.te.(CIP)1895 Ave.ida La Molina Lima Peru 12Lima 15023Peru e.brapa Ge.e.ic Re.ource. and Biote.hnology Parque Estacjao BiologicaFinal Av W5 NorteCaixa Postal 0237270770-917-Brasilia DFBrazil Inte.national Ce.te. for Agricultural Re.e.rch in the.dry Are.s(I CAR dA) Station Exp.INRA-Quich.Rue Hafiane Cherkaoui.Agdal.Rabat-Instituts10111RabatMorocco de.artme.t of Plant Scie.ce. University of Saskatchewan51 Campus Dr.SaskatoonSK S7N 5A8Canada de.artme.t of Plant Agriculture University of GuelphRm 316Crop Science Bldg50 Stone Rd EGuelphON N1G 2W1Canada Ge.ome.Prairie 111 Research DriveSuite 101SaskatoonSKS7N 3R2Canada The.j.me. Hutt on Institute Errol RoadInvergowrieDundeeDD25DAUK CRe. Research Centre for Genomics and Bioinformaticsvia San Protaso 302Fiorenzuola d'Arda29017Italy Ge.ome.British Columbia 400-575 West 8th AvenueVancouverBCV5Z 0C4Canada Inte.national Whe.t Ge.ome.Se.ue.cing Consortium 2841 NE Marywood CtLee's SummitMO.64086USA Forage.Scie.ce Grasslands Research CentreAgResearchPalmerston North4410New Zealand Que.nsla nd Alliance.for Agriculture.and Food Inn ovation University of QueenslandBrisbaneQLD 4072Australia Institute.of Biote.hnology and Ge.e.ic e.gine.ring(IBGe. Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur 1706Bangladesh Southe.n Cross Unive.sity PO Box 157LismoreNSW 2480Australia Royal Botanic Garde.s KewRichmondSurreyTW93AEUK Fe.d the.Future.Innovation Lab for Crop Improve.e.t 431 Weill HallCornell UniversityIthacaNY14853USA de.artme.t of Botany and Biodive.sity Re.e.rch Ce.tre University of British ColumbiaVancouverBC V6R 2A5Canada Crops For the.Future.UK)CIC 76-80 Baddow Road ChelmsfordEs

Ove. the.past 70 ye.rs,the.world has witne.se. e.traordinary growth in crop productivity,e.able. by a suite.of te.hnological advance.,including highe. yie.ding crop varie.ie.,improve. farm manage.e.t,synthe.ic agroche.icals,and agricultural *** this"Gre.n Re.olution"inte.sifie. crop production,and is cre.ite. with re.ucing famine.and malnutrition,its be.e.its we.e.accompanie. by se.e.al unde.irable.collate.al e.fe.ts(Pingali,2012).The.e.include.a narrowing of agricultural biodive.sity,ste.ming from incre.se. monoculture.and gre.te. re.iance.on a smalle. numbe. of crops and crop varie.ie. for the.maj.rity of our *** re.uction in dive.sity has cre.te. vulne.abilitie. to pe.t and dise.se.e.ide.ics,climate.variation,and ultimate.y to human he.lth(Harlan,1972).

关键词： inte.sifie. crops agricultural

Phase.3 trial of first ge.e.ation prote.se.inhibitor the.apy for he.atitis C virus/human immunode.icie.cy virus coinfe.tion

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World j.urnal of He.atology 2017年第4期9卷 217-223页

作者： Ke.ne.h e.She.man Minhe. Kang Richard Ste.ling Triin Umble.a Kriste. Marks j.0}nife. j.Kise. Be.e.ly Alston-Smith Wayne.Gre.ve. Ade.l A Butt 无 division of dige.tive.dise.se. University of Cincinnati College of Medicine harvard T.h. Chan School of Public he.lth de.artme.t of Gastroe.te.ology Virginia Commonwealth University division of Infe.tious dise.se Weill Cornell Medical School Unive.sity of Colorado School of Pharmacy NIAId-division of AIdS Me.ck and Co Inc. Unive.sity of Pittsburgh School of Me.icine hamad he.lthcare.Quality Institute the.ACTG 5294 BIRTH Study Te.m

AIMTo e.aluate.e.ficacy/safe.y of he.atitis C virus (HCV) prote.se.inhibitor boce.re.ir with pe.ylate. inte.fe.on (Pe.-IFN) alfa and we.ght-base. ribavirin (RBV) in a phase.3 trial. Me.HOdSA prospe.tive. multice.te., phase.3, ope.-labe., single.arm study of Pe.-IFN alfa, we.ght-base. RBV, and boce.re.ir, with a Pe.-IFN/RBV le.d-in phase.was pe.forme.. The.HCV/human immunode.icie.cy virus coinfe.te. study population include. tre.tme.t naïve.(TN) and tre.tme.t e.pe.ie.ce. (Te. patie.ts. Tre.tme.t duration range. from 28 to 48 wk de.e.de.t upon re.ponse.guide. crite.ia. All patie.ts had HCV Ge.otype.1 with a viral load > 10000 IU/mL. Compe.sate. cirrhosis was allowe.. Sample.size.was de.e.mine. to e.tablish supe.iority to historical (Pe.-IFN plus RBV) rate. in sustaine. viral re.ponse.(SVR). Re.ULTSA total of 257 e.rolle. participants we.e.analyze. (135 TN and 122 Te.. In the.TN group, 81.5% we.e.male.and 54.1% we.e.black. In the.Te.group, 76.2% we.e.male.and 47.5% we.e.white. Ove.all SVR12 rate. (HCV RNA P = 0.002). Among the.TN, SVR12 was 42.1% among white. and 27.4% among blacks (P = 0.09). CONCLUSIONThe.trial me. its hypothe.is of improve. SVR compare. to historical controls but ove.all SVR rate. we.e.low. All-oral HCV tre.tme.ts will mitigate.the.e.difficultie..

关键词： Human immunode.icie.cy virus He.atitis C virus Boce.re.ir Pe.ylate. inte.fe.on alfa Ribavirin

Ve.tilation practice. in burn patie.ts—an inte.national prospe.tive.obse.vational cohort study

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Burns & Trauma 2021年第1期9卷 47-57页

作者： Ge.ie.j.Glas j.nne.e.Horn Markus W.Hollmann Be.e.ikt Pre.ke. Kirste. Colpae.t Manu Malbrain Ary Se.pa Ne.o Karim Ase.noune.Marce.lo Gamma de.Abre. Ignacio Martin-Loe.he. Paolo Pe.osi Folke.Sj.e.g j.n M.Binne.ade.Be.ry Cle.fke. Nicole.P.j.ffe.mans paul Knape.Be.t G.Loe. david P.Mackie.Pe.e.le. e.khbaatar Nadia de.e.ris Ande.s Pe.ne. e.a He.re.o Lucia Cachafe.ro Marc j.0}chke.j.0}fre. Lipman Matthie. Le.rand j.hanne. Horte. Athina Lavre.tie.a Ale. Kaze.i Anne.Be.it Guttormse. Fre.e.ik Huss Mark Kol He.e. Wong The.e.e.Starr Luc de.Crop Wilson de.Olive.ra Filho j.a Manoe. Silva j.nior Cintia M.C.Grion Marj.rie.Burne.t Fre.e.ik Mondrup Francois Ravat Mathie. Fontaine.Re.an Le.Floch Mathie. j.0}nne.Morgane.Bacus Maite.Chaussard marcus Le.nhardt Basse. danie. Mikhail j.che. Gille.Aidan Sharke. Nicole.Tromme. Auke.C.Re.dinga Nadine.Vie.2}rs Anna Tilsle. He.ning Onarhe.m Maria Te.e.a Bouza Ale.ande. Agrifoglio Filip Fre.én Tina Palmie.i Lynda e.Painting marcus j.Schultz LAMiNAR inve.tigators Acade.ic Me.ical Ce.te. University of AmsterdamAmsterdamAZ 1105The Netherlands de.artme.t of Anae.the.ia and Inte.sive.The.apy Me.ical Unive.sity of Lublin Ale.e.Racklawickie.1–20-059 Lublin–Poland AZ j.N PALFIj. Ge.T Wate.sportlaan 5–9000 Ge.t–Be.gium ABC Me.ical School SaPauloBangúSP 5001Brazil Se.vice.d’Ane.thésie.Réanimation Chirurgicale Nantes 44093France Unive.sity Hospital Carl Gustav Carus Dresden 01307Germany St j.me. Unive.sity Hospital Dublin D08 NHY1Ireland Unive.sity of Ge.oa GenoaGE 16128Italy Linkoing Unive.sity Hospital Linkoing 58185Sweden Maasstad Hospital RotterdamDZ 3079The Netherlands Re. Cross Hospital BeverwijkLE 1942The Netherlands Martini Hospital GroningenNT 9728The Netherlands Unive.sity of Te.as Me.ical Branch GalvestonTX 77555USA Turin CTO Burn Ce.te. TurinTO 10126Italy Rigshospitale. Copenhagen 2100Denmark La Paz Unive.sity Hospital Madrid 28046Spain Ross Tille. Burn Ce.tre Sunnybrook Health Sciences CentreToronto M4N 3M5Canada Royal Brisbane.and Wome.’s Hospital Queensland UniversityHerstonQLD 4029Australia Australian and Ne. Ze.land Inte.sive.Care.Re.e.rch Ce.tre.Monash Unive.sity MelbourneVIC 3004Australia GH St-Louis-Lariboisière APHPParis 75010France BG Klinik Ludwigshafe. Ludwigshafen 67071Germany Papanikoalou Hospital Thessaloniki 54621Greece Middle.ore.Hospital OtahuhuAuckland 2025New Zealand Hauke.and Unive.sity Hospital Bergen 5021Norway Uppsala Unive.sity Hospital Uppsala 75185Sweden Concord Re.atriation Ge.e.al Hospital NSW University of SydneyConcord 2139Australia Zie.e.huis Ne.we.k Antwe.pe.-Stuive.be.g Antwerpen 2060Belgium Unive.sidade.de.Sao paulo Sao Paulo 01246-903Brazil Unive.sidade.e.tadual de.Londrina Londrina 86057-970Brazil Sunnybrook He.lth Scie.ce. Ce.tre Toronto M4N 3M5Canada CHU Lyon St Luc Lyon 69007France CHU Nante. Se.vice.dáne.the.ie.re.nimation chirugicale Nantes 44093France Hopital Roge. Sale.gro CHRU LilleLille 59037France Saint-Louis Hospital Paris 75010France BG Unive.sity Hospital Be.gmannshe.l Bo

Background:It is unknown whe.he. lung-prote.tive.ve.tilation is applie. in burn patie.ts and whe.he. the. be.e.it from *** study aime. to de.e.mine.ve.tilation practice. in burn inte.sive.care.units(ICUs)and inve.tigate.the.association be.we.n lung-prote.tive.ve.tilation and the.numbe. of ve.tilator-fre. days and alive.at day 28(VFd-28).Me.hods:This is an inte.national prospe.tive.obse.vational cohort study including adult burn patie.ts re.uiring me.hanical *** tidal volume.V_(T))was de.ine. as V_(T)≤8 mL/kg pre.icte. body we.ght(PBW).Le.e.s of positive.e.d-e.piratory pre.sure.Pe.P)and maximum airway pre.sure. we.e.*** association be.we.n V_(T) and VFd-28 was analyze. using a compe.ing risk *** se.tings we.e.pre.e.te. for all patie.ts,focusing on the.first day of *** also compare. ve.tilation se.tings be.we.n patie.ts with and without inhalation ***:A total of 160 patie.ts from 28 ICUs in 16 countrie. we.e.*** V_(T) was use. in 74%of patie.ts,me.ian V_(T) size.was 7.3[inte.quartile.range.IQR)6.2–8.3]mL/kg PBW and did not diffe. be.we.n patie.ts with and without inhalation trauma(p=0.58).Me.ian VFd-28 was 17(IQR 0–26),without a diffe.e.ce.be.we.n ve.tilation with low or high V_(T)(p=0.98).All patie.ts we.e.ve.tilate. with Pe.P le.e.s≥5 cmH_(2)O;80%of patie.ts had maximum airway pre.sure.e.national cohort study we.found that lung-prote.tive.ve.tilation is use. in the.maj.rity of burn patie.ts,irre.pe.tive.of the.pre.e.ce.of inhalation *** of low V_(T) was not associate. with a re.uction in *** re.istration:*** *** of re.istration:9 de.e.be. 2014.

关键词： Me.hanical ve.tilation Inhalation trauma Lung-prote.tive Critical care