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Silver nanoislands on cellulose fibers for chromatographic separation and ultrasensitive detection of small molecules

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Light(Science & Applications) 2016年第1期5卷 796-802页

作者： Hyukjin Jung Moonseong park Minhee Kang ki-hun Jeong Department of Bio and Brain Engineering KAIST Institute for Optical Science and TechnologyKorea Advanced Institute of Science and Technology291 Daehak-roYuseong-guDaejeon 305-701Korea

High-throughput small-molecule assays play essential roles in biomedical diagnosis,drug discovery,environmental analysis,and physiological function *** holds a great potential for the label-free detection of small molecules at extremely low ***,we report the development of nanoplasmonic paper(NP-paper)for the rapid separation and ultrasensitive detection of mixed small ***-paper employs nanogap-rich silver nanoislands on cellulose fibers,which were simply fabricated at the wafer level by using low-temperature solid-state dewetting of a thin silver *** nanoplasmonic detection allows for the scalable quantification and identification of small molecules over broad concentration ***,the combination of chromatographic separation and nanoplasmonic detection allows both the highly sensitive fluorescence detection of mixed small molecules at the attogram level and the label-free detection at the sub-nanogram level based on surface-enhanced Raman *** novel material provides a new diagnostic platform for the high-throughput,low-cost,and label-free screening of mixed small molecules as an alternative to conventional paper chromatography.

关键词： nanoplasmonics paper chromatography plasmon-enhanced spectroscopy silver nanoislands small-molecule assay

Seismic hazard level reduction for existing buildings considering remaining building lifespans

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Earthquake Engineering and Engineering Vibration 2019年第3期18卷 649-661页

作者： Ji-hun park Division of Architecture and Urban Design Incheon National University

Seismic hazard levels lower than those for design of new buildings have been permitted for seismic evaluation and retrofi t of existing buildings due to the relatively short remaining lifespans. The seismic hazard reduction enables costeff ective seismic evaluation and retrofi t of existing buildings with limited structural capacity. The current study proposes seismic hazard reduction factors for Korea, one of low to moderate seismicity regions. The seismic hazard reduction factors are based on equal probabilities of non-exceedance within diff erent remaining building lifespans. A validation procedure is proposed to investigate equality of seismic risk in terms of ductility-based limit states using seismic fragility assessment of nonlinear SDOF systems, of which retrofi t demands are determined by the displacement coeffi cient method of ASCE 41-13 for diff erent target remaining building lifespans and corresponding reduced design earthquakes. Validation result shows that the use of seismic hazard reduction factors can be permitted in conjunction with appropriate lower bounds of the remaining building lifespans.

关键词： seismic hazard level existing building remaining building lifespan probability of limit state

Observation of baroclinic eddies southeast of Okinawa Island

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Science China Earth Sciences 2008年第12期51卷 1802-1812页

作者： park Jae-hun Graduate School of Oceanography University of Rhode Island

In the region southeast of Okinawa, during May to July 2001, a cyclonic and an anticyclonic eddy were observed from combined measurements of hydrocasts, an upward-looking moored acoustic Doppler current profiler (MADCP), pressure-recording inverted echo sounders (PIESs), satellite altimetry, and a coastal tide gauge. The hydrographic data showed that the lowest/highest temperature (T) and salinity (S) anomalies from a 13-year mean for the same season were respectively ?3.0/+2.5°C and ?0.20/+0.15 psu at 380/500 dbar for the cyclonic/anticyclonic eddies. From the PIES data, using a gravest empirical mode method, we estimated time-varying surface dynamic height (D) anomaly referred to 2000 dbar changing from ?20 to 30 cm, and time-varying T and S anomalies at 500 dbar ranging through about ±2 and°C ±0.2 psu, respectively. The passage of the eddies caused variations of both satellite-measured sea surface height anomaly (SSHA) and tide-gauge-measured sea level anomaly to change from about ?20 to 30 cm, consistent with the D anomaly from the PIESs. Bottom pressure sensors measured no variation related to these eddy activities, which indicated that the two eddies were dominated by baro-clinicity. Time series of SSHA map confirmed that the two eddies, originating from the North Pacific Subtropical Countercurrent region near 20°–30°N and 150°–160°E, traveled about 3000 km for about 18 months with mean westward propagation speed of about 6 cm/s, before arriving at the region southeast of Okinawa Island.

关键词： baroclinic eddy southeast of Okinawa Island PIES ADCP

Integrated guidance and control for damping augmented system via convex optimization

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Chinese Journal of Aeronautics 2022年第7期35卷 30-39页

作者： Bong-Gyun park Tae-hun kiM The 1^(st)R&D Institute-4 Agency for Defense DevelopmentDaejeon 34186Republic of Korea

In this paper,an integrated guidance and control approach is presented to improve the performance of the missile *** approach includes damping augmented system with attitude rate feedback to decrease the oscillation during the homing phase for missiles with low *** addition,physical constraints,which can affect the performance of the missile interception,such as acceleration limit,seeker’s look angle,and look angle rate constraints are *** integrated guidance and control problem is formulated as a convex quadratic optimization problem with equality and inequality constraints,and the solution is obtained by a primal–dual interior point *** performance of the proposed method is verified through several numerical examples.

关键词： Convex optimization Damping augmented system Integrated guidance and control Physical constraint Primal-dual interior point method

Towards high-performance and robust anion exchange membranes(AEMs)for water electrolysis:Super-acid-catalyzed synthesis of AEMs

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Journal of Energy Chemistry 2024年第6期93卷 478-510,I0012页

作者： Geun Woong Ryoo Sun Hwa park ki Chang Kwon Jong hun Kang Ho Won Jang Min Sang Kwon Department of Materials Science and Engineering Research Institute of Advanced Materials(RIAM)Seoul National UniversitySeoul 08826Republic of Korea Interdisciplinary Materials Measurement Institute Korea Research Institute of Standards and Science(KRISS)Daejeon 34113Republic of Korea Department of Chemical and Biological Engineering and Institute of Chemical ProcessSeoul National UniversitySeoul 08826Republic of Korea Department of Applied Measurement Science University of Science and TechnologyDaejeon 34113Republic of Korea

The increasing demand for hydrogen energy to address environmental issues and achieve carbon neutrality has elevated interest in green hydrogen production,which does not rely on fossil *** various hydrogen production technologies,anion exchange membrane water electrolyzer(AEMWE)has emerged as a next-generation technology known for its high hydrogen production efficiency and its ability to use non-metal ***,this technology faces significant challenges,particularly in terms of the membrane durability and low ionic *** address these challenges,research efforts have focused on developing membranes with a new backbone structure and anion exchange groups to enhance durability and ionic ***,the super-acid-catalyzed condensation(SACC)synthesis method stands out due to its user convenience,the ability to create high molecular weight(MW)polymers,and the use of oxygen-tolerant organic *** the synthesis of anion exchange membranes(AEMs)using the SACC method began in 2015,and despite growing interest in this synthesis approach,there remains a scarcity of review papers focusing on AEMs synthesized using the SACC *** review covers the basics of SACC synthesis,presents various polymers synthesized using this method,and summarizes the development of these polymers,particularly their building blocks including aryl,ketone,and anion exchange *** systematically describe the effects of changes in the molecular structure of each polymer component,conducted by various research groups,on the mechanical properties,conductivity,and operational stability of the *** review will provide insights into the development of AEMs with superior performance and operational stability suitable for water electrolysis applications.

关键词： Green hydrogen production Water electrolysis Anion exchange membrane water electrolyzer(AEMWE) Anion exchange membranes(AEMs) Super-acid-catalyzed condensation(SACC)

Anti-neuro-inflammatory effects of Nardostachys chinensis in lipopolysaccharide-and lipoteichoic acid-stimulated microglial cells

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Chinese Journal of Natural Medicines 2016年第5期14卷 343-353页

作者： Sun Young park Young hun kim Geuntae park Bio-IT Fusion Technology Research Institute Pusan National University Department of Nanomaterials Engineering Pusan National University

Excessive microglial cell activation is related to the progression of chronic neuro-inflammatory disorders. Heme oxygenase-1(HO-1) expression mediated by the NFE2-related factor(Nrf-2) pathway is a key regulator of neuro-inflammation. Nardostachys chinensis is used as an anti-malarial, anti-nociceptive, and neurotrophic treatment in traditional Asian medicines. In the present study, we examined the effects of an ethyl acetate extract of N. chinensis(EN) on the anti-neuro-inflammatory effects mediated by HO-1 up-regulation in Salmonella lipopolysaccharide(LPS)- or Staphylococcus aureus lipoteichoic acid(LTA)-stimulated BV2 microglial cells. Our results indicated that EN suppressed pro-inflammatory cytokine production and induced HO-1 transcription and translation through Nrf-2/antioxidant response element(ARE) signaling. EN markedly inhibited LPS- and LTA-induced activation of nuclear factor-kappa B(NF-?B) as well as phosphorylation of mitogen-activated protein kinases(MAPKs) and signal transducer and activator of transcription(STAT). Furthermore, EN protected hippocampal HT22 cells from indirect neuronal toxicity mediated by LPS- and LTA-treated microglial cells. These results suggested that EN impairs LPS- and LTA-induced neuro-inflammatory responses in microglial cells and confers protection against indirect neuronal damage to HT22 cells. In conclusion, our findings indicate that EN could be used as a natural anti-neuro-inflammatory and neuroprotective agent.

关键词： Nardostachys chinensis Anti-inflammation Lipopolysaccharide Lipoteichoic acid Heme oxygenase-1

Optimization of rotor shape for constant torque improvement and radial magnetic force minimization

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Journal of Central South University 2012年第2期19卷 357-364页

作者： CHO Gyu-won WOO Seok-hyun JI Seung-hun park Kyoung-won JANG ki-bong kiM Gyu-tak School of Mechatronics Changwon National University

The design of notch and barrier was optimized in order to improve the characteristics of constant torque while minimizing the cogging torque that occurs as a result of teeth and slot structure. The barrier was installed in order to minimize the cogging torque and torque ripple by finite element method (FEM) with a reduced barrier width toward the center of magnetic pole. The position and width of notch, which can offset cogging torque, can be calculated with energy distribution of air-gap using Fourier series. The optimized model demonstrates a 60% decrease in the cogging torque, a 75.3% decrease in the torque ripple and a 3% increase in the operating torque when compared with the basic model.

关键词： permanent magnet synchronous motor barrier notch radial magnetic force cogging torque

Induced atrial fibrillation during defibrillation test on implantation of subcutaneous implantable cardioverter defibrillator

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Journal of Geriatric Cardiology 2020年第8期17卷 525-527页

作者： ki-hun kim Sang-Hoon Seol Jino park Yeo-Jeong Song Seunghwan kim Dong-kie kim Division of Cardiology Department of Internal MedicineHaeundae Paik HospitalInje University College of MedicineBusanKorea

The subcutaneous implantable cardioverter defibrillator(S-ICD)has become an alternative to the transvenous ICD in indicated ***,inappropriate shock or failed ventricular tachycardia/fibrillation conversion is the most... 详细信息

关键词： Atrial fibrillation Defibrillation test Subcutaneous implantable cardioverter defibrillator

Polymorphic ventricular tachycardia during phase Ⅱ cardiac rehabilitation in a patient with heart failure: a case report

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Journal of Geriatric Cardiology 2020年第1期17卷 64-66页

作者： Hee-Eun Choi Chul kim Se-Heum park Doo-Il kim ki-hun kim Dong-kie kim Seunghwan kim Jino park Department of Rehabilitation Medicine Inje University College of MedicineHaeundae Paik HospitalBusanSouth Korea Department of Rehabilitation Medicine Inje University College of MedicineSanggye Paik HospitalSeoulSouth Korea Department of Internal Medicine Inje University College of MedicineHaeundae Paik HospitalBusanSouth Korea

A 67-year-old man with a history of a prior cardiac arrest with ventricular fibrillation(VF)due to myocardial infarction underwent phase I(inpatient)and II(outpatient)cardiac rehabilitation(CR)exercise *** the 33th CR session,15 min after the start of exercise training,the patient had syncope with evidence of a polymorphic and wide QRS complex tachycardia on electrocardiogram(ECG)*** initiation of a polymorphic ventricular tachycardia was evidenced by the coupled premature ventricular complex observed in the ECG monitoring screen(Figure 1).

关键词： Cardiac rehabilitation Heart failure Ventricular tachycardia