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Characterization of meiotic chromosome behavior in the autopolyploid Saccharum spontaneum reveals preferential chromosome pairing without distinct DNA sequence variation

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作物学报:英文版 2023年第5期11卷 1550-1558页

作者： Xin Zhang Zhuang Meng Jinlei Han Haris khurshid Ayman Esh Robert Hasterok Kai Wang School of Life Sciences Nantong UniversityNantong 226019JiangsuChina Plant Cytogenetics and Molecular Biology Group Institute of BiologyBiotechnology and Environmental ProtectionFaculty of Natural SciencesUniversity of Silesia in KatowiceKatowice 40-032Poland College of Agriculture Fujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Sugar Crops Research Institute Agriculture Research CenterGiza 12111Egypt Oilseeds Research Program National Agricultural Research CentreIslamabad 44000Pakistan

Autopolyploidy and allopolyploidy may represent an evolutionary advantage and are more common in plants than assumed. However, less attention has been paid to autopolyploidy than to allopolyploidy,and its evolutionary consequences are largely unclear, especially for plants with high ploidy levels. In this study, we developed oligonucleotide(oligo)-based chromosome painting probes to identify individual chromosomes in S. spontaneum. Using fluorescence in situ hybridization(FISH), we investigated chromosome behavior during pachytene, metaphase, anaphase, and telophase of meiosis I(MI) in autotetraploid,autooctoploid, and autodecaploid S. spontaneum clones. All autopolyploid clones showed stable diploidized chromosome behavior;so that homologous chromosomes formed almost exclusively bivalents during MI. Two copies of homologous chromosome 8 with similar sizes in the autotetraploid clone showed preferential pairing with each other with respect to the other copies. However, sequence variation analysis showed no apparent differences among homologs of chromosome 8 and all other chromosomes. We suggest that either the stable diploidized pairing or the preferential pairing between homologous copies of chromosome 8 in the studied autopolyploid sugarcane are accounted for by unknown mechanisms other than DNA sequence similarity. Our results reveal evolutionary consequences of stable meiotic behavior in autopolyploid plants.

关键词： Autopolyploidy Saccharum spontaneum Meiosis I Chromosome behavior Chromosome pairing

Multiscale engineering of microbial cell factories: A step forward towards sustainable natural products industry

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Synthetic and Systems Biotechnology 2022年第1期7卷 586-601页

作者： Muhammad Hammad Hussain Muhammad Zubair mohsin Waqas Qamar Zaman Junxiong Yu Xueli Zhao Yanlong Wei Yingping Zhuang Ali mohsin Meijin Guo State Key Laboratory of Bioreactor Engineering East China University of Science and TechnologyShanghai200237PR China Institute of Environmental Sciences and Engineering School of Civil and Environmental EngineeringNational University of Sciences and Technology(NUST)Sector H-12Islamabad44000Pakistan

Microbial cell factories(bacteria and fungi)are the leading producers of beneficial natural products such as lycopene,carotene,herbal medicine,and biodiesel *** microorganisms are considered efficient due to their effective bioprocessing strategy(monoculture-and consortial-based approach)under distinct processing ***,the advancement in genetic and process optimization techniques leads to enhanced biosynthesis of natural products that are known functional ingredients with numerous applications in the food,cosmetic and medical *** consortia and monoculture thrive in nature in a small proportion,such as wastewater,food products,and *** similitude to natural consortia,it is possible to engineer artificial microbial consortia and program their behaviours via synthetic biology ***,this review summarizes the optimization of genetic and physicochemical parameters of the microbial system for improved production of natural ***,this review presents a brief history of natural consortium and describes the functional properties of *** review focuses on synthetic biology tools that enable new approaches to design synthetic consortia;and highlights the syntropic interactions that determine the performance and stability of synthetic *** particular,the effect of processing conditions and advanced genetic techniques to improve the productibility of both monoculture and consortial based systems have been greatly *** this context,possible strategies are also discussed to give an insight into microbial engineering for improved pro-duction of natural products in the *** summary,it is concluded that the coupling of genomic modifications with optimum physicochemical factors would be promising for producing a robust microbial cell factory that shall contribute to the increased production of natural products.

关键词： Genetic and process optimization techniques Monoculture Natural products Synthetic consortia Synthetic biology tools

Socio-political and ecological stresses on traditional pastoral systems:A review

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Journal of Geographical Sciences 2019年第10期29卷 1758-1770页

作者： MUHAMMAD khurshid MOHAMMAD Nafees ABDULLAH Khan MEHMET Somuncu ASHFAQ Ahmad Khan WAJID Rashid Department of Environmental Sciences The University of HaripurKhyber Pakhtunkhwa 22620 Pakistan Department of Environmental Sciences University of PeshawarPeshawar 25000 Pakistan Department of Geography Ankara UniversitySihhiye 06100 Ankara Turkey Department of Geography Karabuk UniversityKarabuk 78000 Turkey Department of Environmental Sciences The University of SwatSwat 19130 Pakistan

Pastoralism is a viable socio-economic system-shaped by landless and agro-pastoral communities in many pastoral regions of the world. This system is mainly based on seasonal migration of pastoralists and their livestock herds between upland and lowland pastures. Traditionally pastoral activities make significant contributions to mountain livelihood subsistence, regional economies and environmental sustainability. However, the pastoralist’s lifestyle and their economies are increasingly confronted to various socio-political, economic and ecological stresses from the last few decades. Extensive literature reviewed on this subject with the aim to explore the current emerging challenges faced by pastoral communities in different pastoral regions. It has been revealed from literature that the prevalent socio-political and economic stress on pastoralism caused by modernization, insecure land tenure, integration of market economy, civil insecurities and pastoralist’s exclusion in states policies while ecological stress on pastoral activities emerged with increasing focus on nature conservation in pastoral regions and climate change induced hazards and disasters. As a consequence of these challenges, pastoral households are abandoning livestock herding–as a traditional way of life and are in continuous transition to transform their pastoral practices and institutions. Thus, the attention and consultation of key stakeholders are needed toward pastoral resource development that improve and sustain traditional pastoral practices in a socio-politically and ecologically stressed environment of the world.

关键词： pastoralism marginalization pastoral system pastures livestock pastoralists

Multimodal Transportation Planning for Multicommodity Flow Problem

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Multimodal Transportation Planning for Multicommodity Flow P...

作者： mohsin ALI（莫辛）东南大学

学位级别：硕士

Multimodal transportation refers to a combination using at least two modes of transportation to transport good or service such as truck,air,railway or *** transportation has become increasingly important and dominating in the multicommodity flow *** to the advantage of truck transportation in that it can provide door to door service,we always see the truck transportation as a component in the combination of modes for multimodal freight transportation like rail and truck transportation（piggyback）,sea and truck transportation（Fishback）,or air and truck transportation（birdy back）.The Primary focus of our research has to presented a methodology for a more efficient way of freight transportation planning through the use of a multimodal *** to the necessity of using truck transportation as a component in the network of multimodal transportation,the complexity of planning the multimodal transportation network emerges because of the difference of truck transportation from other modes of ***,rail,and air transportation services are often scheduled services,which mean these three modes can serve only on fixed schedule of departure and arrival times;on the other hand,truck transportation is more flexible in the aspect of time in that it can provide flexible time *** plan the multimodal freight transportation network in an efficient manner,the planner has to synchronize the flexible-time service of truck transportation with the scheduled-time service of rail *** paper considers the network of a company that operates express delivery service by transporting customers’ demands through the multimodal transportation network of rail and truck *** authors formulate the problem as a multicommodity flow problem on a representative *** objective of this optimization model is to minimize the total transportation cost and the travel time of each commodity,which is defined by its origin-destination（

关键词： Multicommodity Flow Problem Multimodal Transportation Transportation Cost

Energy Theft Detection in Smart Grids:Taxonomy,Comparative Analysis,Challenges,and Future Research Directions

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IEEE/CAA Journal of Automatica Sinica 2022年第4期9卷 578-600页

作者： mohsin Ahmed Abid Khan Mansoor Ahmed Mouzna Tahir Gwanggil Jeon Giancarlo Fortino Francesco Piccialli the Department of Computer Science COMSATS University Islamabad the Department of Computer Science School of ComputingEngineering and Digital TechnologiesTeesside University the Innovative Value Institute Maynooth University the Department of Computer Science Bahria University the School of Electronic Engineering Xidian University the Department of Embedded Systems Engineering Incheon National University IEEE the Department of Informatics ModelingElectronics and SystemsUniversity of Calabria the Department of Mathematics and Applications“R.Caccioppoli” University of Naples FedericoⅡ

Electricity theft is one of the major issues in developing countries which is affecting their economy *** with the introduction of emerging technologies,this issue became more *** many new energy theft detection(ETD)techniques have been proposed by utilising different data mining(DM)techniques,state&network(S&N)based techniques,and game theory(GT)***,a detailed survey is presented where many state-of-the-art ETD techniques are studied and analysed for their strengths and *** levels of taxonomy are presented to classify state-of-the-art ETD *** types and ways of energy theft and their consequences are studied and summarised and different parameters to benchmark the performance of proposed techniques are extracted from *** challenges of different ETD techniques and their mitigation are suggested for future *** is observed that the literature on ETD lacks knowledge management techniques that can be more effective,not only for ETD but also for theft *** can help in the prevention of energy theft,in the future,as well as for ETD.

关键词： Challenges comparative analysis energy theft detection future research directions smart grid taxonomy

Inducing opto-electronic and spintronic trends in bilayer h-BN through TMO3 clusters incorporation: Ab-initio study

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Chinese Physics B 2019年第11期28卷 284-294页

作者： Irfan Ahmed Muhammad Rafique Mukhtiar Ahmed Mahar Abdul Sattar Larik mohsin Ali Tunio Yong Shuai Mehran University of Engineering and Technology SZABCampusKhairpur Mirs’Pakistan School of Energy Science and Engineering Harbin Institute of TechnologyHarbin 150001China Mehran University of Engineering and Technology JamshoroSindhPakistan

The band structure, magnetism, charge distribution, and optics parameters of TMO3–h-BN hybrid systems are investigated by adopting first-principles study(FPS) calculations. It is observed that the TMO3 clusters add finite magnetic moments to bilayer h-BN(BL/h-BN), thereby making it a magnetic two-dimensional(2D) material. Spin-polarized band structures for various TMO3–BL/h-BN hybrid models are calculated. After the incorporation of TMO3, BL/h-BN is converted into semimetal or conducting material in spin up/down bands, depending on the type of impurity cluster present in BL/h-BN lattice. Optics parameters are also investigated for the TMO3–BL/h-BN complex systems. The incorporation of TMO3 clusters modifies the absorption and extinction coefficient in visible range, while static reflectivity and refraction parameter increase. It can be surmised that the TMO3 substitution in BL/h-BN is a suitable technique to modify its physical parameters thus making it functional for nano/opto-electronic applications, and an experimental approach can be adapted to reinforce the outcomes of this study.

关键词： bilayer h-BN band structure density of states magnetic moments optics

A study of nonlinear biochemical reaction model

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International Journal of Biomathematics 2016年第5期9卷 121-129页

作者： Muhammad Asad Iqbal Syed Tauseef Mohyud-Din Bandar Bin-mohsin Department of Mathematics HITEC University Taxila Pakistan Department of Mathematics College of Science King Saud University Riyadh Saudi Arabia

The present study deals with the introduction of an alteration in Legendre wavelets method by availing of the Picard iteration method for system of differential equations and named it Legendre wavelet-Picard method （LWPM）. Convergence of the proposed method is also discussed. In order to check the competence of the proposed method, basic enzyme kinetics is considered. Systems of nonlinear ordinary differential equations are formed from the considered enzyme-substrate reaction. The results obtained by the proposed LWPM are compared with the numerical results obtained from Runge-Kutta method of order four （RK-4）. Numerical results and those obtained by LWPM are in excellent conformance, which would be explained by the help of table and figures. The proposed method is easy and simple to implement as compared to the other existing analytical methods used for solving systems of differential equations arising in biology, physics and engineering.

关键词： Legendre wavelets method Picard iteration method nonlinear biochemical reaction model Runge- Kutta method of order four.

Preparation and Control of the Formation of Single Core and Clustered Nanoparticles for Biomedical Applications Using a Versatile Amphiphilic Diblock Copolymer

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Nano Research 2010年第12期3卷 852-862页

作者： Hongwei Chen Julie Yeh Liya Wang Hafsa khurshid Nan Peng Andrew YWang Hui Mao Department of Radiology Center for Systems ImagingEmory University School of MedicineAtlantaGeorgia 30322USA Department of Physics and Astronomy University of DelawareNewarkDelaware 19716USA Department of Rehabilitation Medicine Chinese PLA General Hospital28 Fuxing RoadBeijing 100853China Ocean NanoTech LLC2143 Worth LaneSpringdaleArkansas 72764USA

We report the application of a versatile diblock copolymer,poly(ethylene oxide)-b-poly(γ-methacryloxypropyl trimethoxysilane)(PEO-b-PγMPS),to prepare nanocrystals such as iron oxide nanoparticles or quantum dots,with either a single core or multi-core cluster,for biomedical *** amphiphilic copolymer comprises both a hydrophilic PEO segment and a hydrophobic segment with a“surface anchoring moiety”(the silane group)which can interact effectively with the hydrophobic nanocrystals through ligand *** of the unique features of this work is that we can control the formation of either single core nanoparticles or multi-core nanoclusters by simply varying the conditions of ligand exchange and aging of the mixture of block copolymer and nanoparticles without needing to change the *** morphologies of the resulting single core nanoparticles or multi-core nanoclusters were confirmed by dynamic light scattering and transmission electron *** clustered nanoparticles exhibit enhanced physicochemical properties that are beyond those expected from a simple accumulation of individual ***,the hybrid nanoparticles containing both magnetic iron oxide nanoparticles and optical quantum dots obtained using our strategy provide have combined magnetic and optical functionalities that allow for potential new and expanded biomedical applications,as demonstrated by their use for magnetic resonance imaging and biomarker-targeted cell imaging.

关键词： Magnetic nanoparticles quantum dots nanoparticle coating copolymer multifunctional nanoparticles imaging

Essential Features Preserving Dynamics of Stochastic Dengue Model

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Computer Modeling in Engineering & Sciences 2021年第1期126卷 201-215页

作者： Wasfi Shatanawi Ali Raza Muhammad Shoaib Arif Muhammad Rafiq Mairaj Bibi Muhammad mohsin Department of Mathematics and General Sciences Prince Sultan UniversityRiyadhSaudi Arabia Department of Medical Research ChinaMedical University HospitalChina Medical UniversityTaichung40402Taiwan Department of Mathematics Hashemite UniversityZarqaJordan Stochastic Analysis&Optimization Research Group Department of MathematicsAir UniversityIslamabad44000Pakistan Department of Mathematics National College of Business Administration and EconomicsLahorePakistan Department of Mathematics Faculty of SciencesUniversity of Central PunjabLahore54500Pakistan Department of Mathematics Comsats University IslamabadIslamabadPakistan Department of Mathematics Uppsala UniversityUppsalaSweden

Nonlinear stochasticmodelling plays an important character in the different fields of sciences such as environmental,material,engineering,chemistry,physics,biomedical engineering,and many *** the current study,we studied the computational dynamics of the stochastic dengue model with the real material of the ***,boundedness,and dynamical consistency are essential features of stochastic *** focus is to design the computational method which preserves essential features of the *** stochastic non-standard finite difference technique is most efficient as compared to other techniques used in *** and comparison were explored in favour of ***,we address the comparison between the stochastic and deterministic models.

关键词： Dengue model stochastic ordinary differential equations numerical methods convergence of the proposed method