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Seroprevalence of SARS-COV-2 Exposure among “High-Risk” Populations (Healthcare Workers, People Who Attend Markets, and School Children) in Zanzibar

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Advances in Infectious Diseases 2024年第1期14卷 34-55页

作者： Ame Masemo Solomon Mwakasungula khamis Kheir Erick Mgina Nahya khamis Irabi Kassim Bihila Bakar khamis salim Sarah Mswata Kibwana Omar Theckla Kazimoto Linzy Elton Honorati Masanja Mayassa Ally Zanzibar Health Research Institute Binguni Zanzibar Ifakara Health Institute Bagamoyo Tanzania National Institute for Medical Research Muhimbili Centre Dar es Salaam Tanzania Binguni Public Health Laboratory Binguni Zanzibar Department of Microbiology Mnazi Mmoja Hospital Stone Town Zanzibar Centre for Clinical Microbiology Royal Free Hospital Campus University College London London UK

In Zanzibar, from the start of the pandemic in March 2020 to the time of sampling in December 2020, SARS-CoV-2 seroprevalence data was limited. We conducted a seroprevalence study to evaluate the magnitude of SARS-CoV-2 exposure among healthcare workers, school children, and people who attended general markets in Zanzibar. The objectives of the study were to analyse the total antibodies from selected higher-risk population groups in order to determine magnitude in SARS CoV-2 exposure. Blood samples were collected from eligible and consented participants (adults and children), and their serum was analyzed for total antibodies against SARS-CoV-2 using ELISA. A questionnaire was used to collect participants’ demographic and clinical data. The overall SARS-CoV-2 seroprevalence across all age groups was 33%, and a higher seroprevalence was observed in the 40 - 49 years’ age group relative to other ages as well as in those who attended markets. A runny nose (18.8% of participants) was the most frequently reported SARS-CoV-2 infection-related symptom. Multivariable analysis showed significantly higher odds of infection in people living in urban districts. The findings provide insight into SARS-CoV-2 infection among school children, health workers, and people who attended markets in Zanzibar in the early stages of the pandemic. Exposure in these groups might have been influenced by infection and prevention strategies taken by the government, as well as shopping behavior, school overcrowding, and population density in urban settings. The study had methodological limitations, including cross-sectional design. Further, well-designed, longitudinal studies are recommended to understand exposure and transmission at a population level.

关键词： SARS-CoV-2 Seroprevalence Zanzibar ELISA COVID-19

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Novel energy recovery from an integrated municipal solid waste and leachate treatment system

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Waste Disposal and Sustainable Energy 2024年第1期6卷 53-61页

作者： Siti Salwa khamis Hadi Purwanto Hamzah Mohd Salleh Alya Naili Rozhan Mohamed Abdur Rahman Mahammadsalman Warimani Noor Alam Faculty of Engineering International Islamic University MalaysiaJalan Gombak53100Kuala LumpurMalaysia Department of Engineering Management Universitas Internasional Semen IndonesiaGresikIndonesia Halalan Thayyiban Research Centre Sultan Sharif Ali Islamic UniversityBandar Seri BegawanBrunei Department of Mechanical Engineering P.A.College of EngineeringMangaloreKarnataka574153India Department of Mechanical Engineering Malaysia-Japan International Institute of TechnologyUniversity of Technology Malaysia54100Kuala LumpurMalaysia

Population growth,waste generation,and massive waste mismanagement have led to environmental *** of municipal solid waste(MSW)requires an efficient and sustainable integrated *** integrated thermal processing of MSW is one of the best waste management *** this study,energy analysis of MSW is carried out based on the material and energy balance of 2000 kg wet MSW,which contains 50%*** the leachate is removed,the dry MSW is sent for carbon content enhancement in carbonization to produce MSW-based ***,the combustion of MSW-based char provided high heat and syngas to be used in a hydrothermal process for MSW leachate *** result shows that the char fuel of MSW produces a sufficient amount of energy,13501.29 MJ(84.55%),in the form of synthetic gas by-product,which has a big potential as an energy *** novelty of the proposed integrated thermal system is to produce 84.55%synthetic gas by-product,which is used for electricity production,cooking,food,and heat energy for industrial *** proposed applications of this paper offer insightful information for policymaking regarding novel MSW techniques,which are economical,energy-efficient,and environmentally ***,it increases the effectiveness of MSW utilization.

关键词： Energy Carbonization Hydrothermal Municipal solid waste Integrated system

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Assessing the Variability of Extreme Weather Events and Its Influence on Marine Accidents along the Northern Coast of Tanzania

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American Journal of Climate Change 2024年第3期13卷 499-521页

作者： Faki A. Ali Kombo Hamad Kai Sara Abdalla khamis Zanzibar Office Tanzania Meteorlogical Authority (TMA) Zanzibar Tanzania Department of Natural Science State University of Zanzibar (SUZA) Zanzibar Tanzania

The marine accidents are among the main components of the Zanzibar Disaster Management Policy (2011) and the Zanzibar Blue Economy Policy (2020). These policies aimed to institute legal frame works and procedures for reducing both the frequency of marine accidents and their associated fatalities. These fatalities include deaths, permanent disabilities and loss of properties which may result into increased poverty levels as per the sustainable development goal one (SDG1) which stipulates on ending the poverty in all its forms everywhere. Thus, in the way to support these Government efforts, the influence of climate and weather on marine accidents along Zanzibar and Pemba Channels was investigated. The study used the 10 years (2013-2022) records of daily rainfall and hourly wind speed acquired from Tanzania Meteorological Authority (TMA) (for the observation stations of Zanzibar, Pemba, Dares Salaam and Tanga), and the significant wave heights data, which was freely downloaded from Globally Forecasting System (GFS-World model of 13 km resolution). The marine accident records were collected from TASAC and Zanzibar Maritime Authority (ZMA), and the anecdotal information was collected from heads of quay and boat captains in different areas of Zanzibar. The Mann Kendal test, was used to determine the slopes and trends direction of used weather parameters, while the Pearson correlations analysis and t-tests were used to understand the significance of the underlying relationship between the weather and marine accidents. The paired t-test was used to evaluate the extent to which weather parameters affect the marine accidents. Results revealed that the variability of extreme weather events (rainfall, ocean waves and wind speed) was seen to be among the key factors for most of the recorded marine accidents. For instance, in Pemba high rainfall showed an increasing trend of extreme rainfall events, while Zanzibar has shown a decreasing trend of these events. As for extreme wind

关键词： Marine Accidents Bad Weather Events Extreme Wind Speed Extreme Rainfall Correlation

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Pediatric and adult liver transplantation in Bahrain: The experiences in a country with no available liver transplant facilities

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World Journal of Transplantation 2024年第1期14卷 96-111页

作者： Hasan M Isa Fatema A Alkharsi Jawad K khamis Sawsan A Hasan Zainab A Naser Zainab N Mohamed Afaf M Mohamed Shaikha A Altamimi Department of Pediatrics Salmaniya Medical ComplexManama 26671Bahrain Department of Pediatrics Arabian Gulf UniversityManama 26671Bahrain Department of Medicine Salmaniya Medical ComplexManama 26671Bahrain Public Health Directorate Ministry of HealthManama 26671Bahrain The Overseas Office Supreme Committee for Treatment AbroadMinistry of HealthManama 26671Bahrain

BACKGROUND Liver transplantation(LT)is a life-saving procedure for patients with end-stage liver disease and has become the standard and most effective treatment method for these *** are many indications for LT that vary between countries and *** outcome of LT depends on the available facilities and surgical expertise,as well as the types of liver graft donors *** To assess the clinical characteristics of patients from Bahrain who underwent LT overseas,and analyze factors affecting their *** In this retrospective cohort study,we reviewed the medical records and overseas committee registry information of all pediatric and adult patients who were sent overseas to undergo LT by the Pediatric and Medical Departments of Salmaniya Medical Complex and Bahrain Defence Force Hospital via the Overseas Treatment Office,Ministry of Health,Kingdom of Bahrain,between 1997 and *** data,LT indication,donor-recipient relationship,overseas LT center,graft type,post-LT medications,and LT complications,were *** measured included the overall and 5-year LT survival ***’s exact,Pearsonχ2,and Mann-Whitney U tests were used to compare the pediatric and the adults’group in terms of clinical characteristics,donor-recipient relationship,medication,complications,and *** analysis was estimated via the Kaplan-Meier’s *** and multivariate analyses were used to detect predictors of *** Of the 208 eligible patients,170(81.7%)were sent overseas to undergo LT while 38(18.3%)remained on the waiting *** the 170 patients,167(80.3%)underwent LT and were included in the *** majority of the patients were Bahraini(91.0%),and most were males(57.5%).One-hundred-and-twenty(71.8%)were adults and 47(28.3%)were *** median age at transplant was 50.0[interquartile range(IQR):14.9–58.4]*** main indication for pediatric LT was biliary atresia(31.9%),while that of adult LT was

关键词： Overseas liver transplantation End-stage liver disease Liver transplant facilities Liver donor Biliary atresia Hepatitis C

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硫醇介导细胞摄取机制与应用研究进展

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精细化工 2024年

作者：魏泓贝张慧 MASTER Mwafulirwa khamis Abdalla 孙晓龙西安交通大学生命科学与技术学院生物医学信息工程教育部重点实验室

细胞摄取是生物体内多种生物活性物质进入细胞的主要途径之一。硫醇介导的摄取通过巯基化物与细胞内的巯基-二硫键进行动态共价交换，然后通过融合、内吞或直接跨膜转运等方式完成对物质的递送，在提高治疗效果和生物活性物质的应用效... 详细信息

细胞摄取是生物体内多种生物活性物质进入细胞的主要途径之一。硫醇介导的摄取通过巯基化物与细胞内的巯基-二硫键进行动态共价交换，然后通过融合、内吞或直接跨膜转运等方式完成对物质的递送，在提高治疗效果和生物活性物质的应用效率方面具有优势。该文综述了具有不同环张力二硫化物、聚二硫醚、环状寡硫族化合物、二硒化物、动态硫醚键、迈克尔受体等分子结构与巯基的相互作用机制；总结了通过这一途径对量子点、核酸、蛋白质、纳米颗粒、药物和脂质体等物质在细胞内的递送，以及通过封闭细胞内的巯基来抑制细胞对通过这一途径进入的化合物的摄取；此外，介绍了硫醇介导摄取在植物和微生物中的应用；最后，展望了硫醇介导摄取未来的发展趋势。

关键词：动态共价交换硫醇介导摄取作用机制物质递送治疗

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Systemic oncological therapy in breast cancer patients on dialysis

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World Journal of Clinical Oncology 2024年第6期15卷 730-744页

作者： Salman Khan Ghada Araji Ekrem Yetiskul Praneeth Reddy Keesari Fadi Haddadin Zaid khamis Varun Chowdhry Muhammad Niazi Sarah Afif Meekoo Dhar Suzanne El-Sayegh Department of Internal Medicine Northwell Health-Staten Island University HospitalStaten IslandNY 10305United States Department of Hematology and Oncology Northwell Health-Staten Island University HospitalStaten IslandNY 10305United States Department of Internal Medicine CUNY School of MedicineNew YorkNY 10031United States

The advancement of renal replacement therapy has significantly enhanced the survival rates of patients with end-stage renal disease(ESRD)over ***-ever,this prolonged survival has also been associated with a higher likelihood of cancer diagnoses among these patients including breast *** cancer treatment typically involves surgery,radiation,and systemic therapies,with ap-proaches tailored to cancer type,stage,and patient ***,renal replacement therapy complicates systemic therapy due to altered drug clearance and the necessity for dialysis *** review emphasizes the need for opti-mized dosing and administration strategies for systemic breast cancer treatments in dialysis patients,aiming to ensure both efficacy and ***,ch-allenges in breast cancer screening and diagnosis in this population,including soft-tissue calcifications,are highlighted.

关键词： Breast cancer Systemic therapy Renal replacement therapy Dialysis End-stage renal disease Hormone therapy Chemotherapy

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Porosity,cracks,and mechanical properties of additively manufactured tooling alloys:a review

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Advances in Manufacturing 2022年第2期10卷 175-204页

作者： Prveen Bidare Amaia Jimenez Hany Hassanin khamis Essa School of Mechanical Engineering University of BirminghamBirminghamUK TECNUN Escuela de Ingenieria Universidad de NavarraManuel de Lardizabal 15San Sebastian20018Spain School of Engineering Technologyand DesignCanterbury Christ Church UniversityCanterbury CT11QUUK

Additive manufacturing(AM)technologies are currently employed for the manufacturing of completely functional parts and have gained the attention of hightechnology industries such as the aerospace,automotive,and biomedical *** is mainly due to their advantages in terms of low material waste and high productivity,particularly owing to the flexibility in the geometries that can be *** the tooling industry,specifically the manufacturing of dies and molds,AM technologies enable the generation of complex shapes,internal cooling channels,the repair of damaged dies and molds,and an improved performance of dies and molds employing ***,a reviewof AM processes and materials applied in the tooling industry for the generation of dies and molds is *** technologies used for tooling applications and the characteristics of the materials employed in this industry are first *** addition,the most relevant state-of-the-art approaches are analyzed with respect to the process parameters and microstructural and mechanical properties in the processing of high-performance tooling materials used in AM ***,studies on the AM of ferrous(maraging steels and H13 steel alloy)and non-ferrous(stellite alloys and WC alloys)tooling alloys are also analyzed.

关键词： Additive manufacturing(AM) Tooling alloys Super alloys Hybrid manufacturing Post processing

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The impact of an educational intervention in caregiving outcomes in Jordanian caregivers of patients receiving hemodialysis: A single group pre-and-post test

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International Journal of Nursing Sciences 2018年第2期5卷 144-150页

作者： Eman khamis Alnazly Nursing Deartment Al-Ahliyya Amman UniversityJordan

Objectives:Chronic renal failure affects the physiological,psychological,functional ability,and independent status of the patient,which might result in a burden to the family members caring for *** objective of the study was to identify caregivers'level of burden and establish the impact of educational intervention programs on caregiving ***:This was a one-group pre-test post-test study conducted between April and August 2017 on family caregivers of hemodialysis patients.A convenient sample of 169 caregivers was used.A sociodemographic questionnaire,the OBCS,and BCOS were utilized for data collection,which occurred at baseline and two weeks *** collected data were analyzed using SPSS where t-test determined the impact of the ***:Caregivers were found to be moderately burdened(M=2.73,SD=0.23)and their lives had changed for the worst as a result of caregiving(M=3.17,SD=5.89).There were significant differences in caregiving outcome scores before and after the intervention(P<0.05).Conclusion:Caring for patients receiving hemodialysis adds extra responsibilities to the caregivers'schedule thus leaving them substantially *** caregivers on the required care eased their burden and improved caregiving *** are made that healthcare professionals should assess caregiver burden,and address their physical and mental health *** should also be regularly educated on the regular caregiving tasks to ease their burden.

关键词： Burden Caregiver Hemodialysis Informative materials Self-perceived burden

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Effects of heat and mass transfer on nonlinear MHD boundary layer flow over a shrinking sheet in the presence of suction

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Applied Mathematics and Mechanics(English Edition) 2008年第10期29卷 1309-1317页

作者： Muhaimin R. Kandasamy Azme B. khamis Centre for Science Studies University Tun Hussein Onn Malaysia 86400 Parit Raja Batu Pahat Johor Malaysia

This work is concerned with Magnetohydrodynamic viscous flow due to a shrinking sheet in the presence of suction. The cases of two dimensional and axisymmetric shrinking are discussed. The governing boundary layer equations are written into a dimensionless form by similarity transformations. The transformed coupled nonlinear ordinary differential equations are numerically solved by using an advanced numeric technique. Favorability comparisons with previously published work are presented. Numerical results for the dimensionless velocity, temperature and concentration profiles as well as for the skin friction, heat and mass transfer and deposition rate are obtained and displayed graphically for pertinent parameters to show interesting aspects of the solution.

关键词： shrinking sheet suction at the surface Runge Kutta Gill method magnetic effect

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Thomson and rotation effects during photothermal excitation process in magnetic semiconductor medium using variable thermal conductivity

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Applied Mathematics and Mechanics(English Edition) 2020年第6期41卷 909-926页

作者： K.LOTFY A.K.khamis A.A.EL-BARY M.H.AHMED Department of Mathematics Faculty of ScienceZagazig UniversityZagazig 44519Egypt Department of Mathematics Faculty of ScienceTaibah UniversityAl-Madinah 30002Saudi Arabia Department of Mathematics Faculty of ScienceNorthern Border UniversityArar 91431Saudi Arabia Arab Academy for Science Technology and Maritime TransportAlexandria 1029Egypt

This study investigates a strong magnetic field acting over an elastic rotator semiconductor *** Thomson effect due to the magnetic field during the photothermal transport process is studied,and the thermoelectricity theory is used to explain the behavior of waves in the homogenous and isotropic medium under the effect of variable thermal *** variable thermal conductivity is considered as a linear function of the *** two-dimensional deformation equations are used to describe the overlaps among plasma,electrical,thermal,and magneto-elastic *** charge density of inertia-particles is considered as a function of time for studying the induced electric *** normal mode analysis is used to obtain the exact solutions of the physical field distributions as part of this *** obtain the complete solutions of the physical field quantities,the certain mechanical loads,electromagnetic effects,thermal effects,and plasma recombination process are applied *** results of the physical distributions are graphically depicted and discussed in consideration of the internal heat source,rotation,and Peltier coefficient.

关键词： photothermal thermal conductivity Thomson effect rotation magnetic field Peltier coefficient

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