检索结果-南通市图书馆

Autologous hematopoietic stem cell transplantation conditioning regimens and chimeric antigen receptor T cell therapy in various diseases

引用

World Journal of Transplantation 2024年第1期14卷 32-41页

作者： Shahzaib maqbool maryam Farhan Baloch muhammad Abdul Khaliq khan Azeem khalid Kiran Naimat Department of medicine Holy Family HospitalRawalpindi 46000Pakistan Department of Community medicine Allama Iqbal Medical CollegeLahore 45000Pakistan Department of Community Dentistry Baqai Medical UniversityKarachi 43000Pakistan Department of medicine Allama lqbal Medical CollegeLahore 45000Pakistan Department of medicineLiaquat University of medical and Health Sciences Karachi 43000Pakistan

Conditioning regimens employed in autologous stem cell transplantation have been proven useful in various hematological disorders and underlying malignancies;however,despite being efficacious in various instances,negative consequences have also been *** conditioning regimens were extracted from various literature searches from databases like Pubmed,Google scholar,EmBASE,and *** regimens for each disease were compared by using various end points such as overall survival(OS),progression free survival(PFS),and leukemia free survival(LFS).Variables were presented on graphs and analyzed to conclude a more efficacious conditioning *** multiple myeloma,the most effective regimen was high dose melphalan(mEL)given at a dose of 200/mg/*** comparative results of acute myeloid leukemia were presented and the regimens that proved to be at an admirable position were busulfan(BU)+mEL regarding OS and BU+VP16 regarding *** case of acute lymphoblastic leukemia(ALL),BU,fludarabine,and etoposide(BuFluVP)conferred good disease control not only with a paramount improvement in survival rate but also low risk of ***,for ALL,chimeric antigen receptor(CAR)T cell therapy was preferred in the context of better OS and *** respect to Hodgkin’s lymphoma,mitoxantrone(mITO)/mEL overtook carmustine,VP16,cytarabine,and mEL in view of PFS and vice versa regarding ***-Hodgkin’s lymphoma patients were administered mITO(60 mg/m2)and mEL(180 mg/m2)which showed promising ***,amyloidosis was considered,and the regimen that proved to be competent was mEL 200(200 mg/m2).This review article demonstrates a comparison between various conditioning regimens employed in different diseases.

关键词： Conditioning regimens multiple myeloma Lymphoma Hodgkin Non-Hodgkin Acute leukemia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Quantitative and Qualitative Responses of Hydroponic Tomato Production to Different Levels of Salinity

引用

Phyton-International Journal of Experimental Botany 2024年第6期93卷 1311-1323页

作者： khalid A.Al-Gaadi Ahmed m.Zeyada ElKamil Tola Abdullah m.Alhamdan khalid A.m.Ahmed Rangaswamy madugundu mohamed K.Edrris Department of Agricultural Engineering College of Food and Agriculture SciencesKing Saud UniversityRiyadh11451Saudi Arabia Precision Agriculture Research Chair Deanship of Scientific ResearchKing Saud UniversityRiyadh11451Saudi Arabia Chair of Dates Industry&Technology Deanship of Scientific ResearchKing Saud UniversityRiyadh11451Saudi Arabia Agricultural Research Centre Agricultural Engineering Research Institute(AEnRI)Giza12619Egypt

From economic and nutritional points of view,tomato is,historically,considered one of the most important *** signiﬁcant yield reduction,most commercial cultivars of tomato crops are sensitive to moderate levels of ***,high levels of salt stress can negatively affect the yield and quality of tomato ***,this study was conducted to evaluate the yield and fruit quality of three tomato cultivars(Forester,Ghandowra-F1,and Feisty-Red)cultivated hydroponically,under three different levels of nutrient solution *** of tomato fruits was performed based on quantity(number and weight of fruits,and total fruit yield),physical quality(color andﬁrmness),and chemical quality(refractometric index“Brix”,pH,EC,K^(+),Na^(+),and NO_(3)-).Experiments were conducted using three salinity levels of the nutrient solution with electrical conductivity values(dSm^(-1))of 2.5(control),6.0,and *** showed that the studied tomato cultivars were signiﬁcantly inﬂuenced by high salinity(9.5 dSm^(-1))in comparison to the low(2.5 dSm^(-1))and medium(6.0 dSm^(-1))levels of *** average,the highest fruit weight per plant of 1944.84 g and total fruit yield of 4.42 kgm^(-2) were observed at the low salinity level;however,no signiﬁcant differences were obtained in the two yield factors(single fruit weight and total fruit yield)for the low and medium salinity *** the other hand,a signiﬁcant reduction in tomato yield(31%)was associated with the high salinity level compared to the yield at low and medium salinity *** of physical quality parameters showed highly signiﬁcant differences among all salinity *** average,the maximum value of color change(1.72)was associated with the medium salinity level,and the maximum value ofﬁrmness(9.61 Ncm^(-1))was recorded at the high salinity *** levels and tomato cultivars introduced signiﬁcant differences in chemical quality parameters;however,no signiﬁcant differences in these

关键词： Quality cultivars yield color ﬁrmness brix

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Existence results and behavior analysis for nonlinear age-dependent population dynamics problems with conformable fractional operator

引用

International Journal of Biomathematics 2024年第5期17卷 229-256页

作者： Hiba El Asraoui m'hamed El Omari Ali El mfadel khalid Hilal Laboratory of Applied mathematics Scientific Computing Sultan moulay Slimane University BP 523 Beni MellalMorocco

In this paper,we investigate the existence of solutions and analyze the large-time behavior for Gurtin-maccamy population model involving conformable fractional *** a preliminary step,we construct a generic structure of the solution associated with our proposed model by utilizing some basic properties and tools of conformable fractional *** establish the existence of a unique solution of the given model with the given initial *** last,by using the upper and lower solutions for the characteristic equation,we define the upper and lower boundaries for the obtained solution and describe the large-time behavior of the total population.

关键词： Age-dependent population conformable fractional operator upper and lower boundary of the solution dynamics of populations

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Comprehensive 3-Steps methodology for Vibration-Based Fault Detection,Diagnosis and Localization in Rotating machines

引用

Journal of Dynamics, monitoring and Diagnostics 2024年第1期3卷 49-58页

作者： khalid m.Almutairi Jyoti K.Sinha Dynamics Laboratory School of EngineeringThe University of ManchesterManchester M139PLUK

In any industry,it is the requirement to know whether the machine is healthy or not to operate machine *** the machine is not healthy then what is the fault in the machine and then finally its *** paper is proposing a 3-Steps methodology for the machine fault diagnosis to meet the industrial requirements to aid the maintenance *** Step-1 identifies whether machine is healthy or faulty,then Step-2 detect the type of defect and finally its location in *** method is extended further from the earlier study on the 2-Steps method for the rotor defects only to the 3-Steps methodology to both rotor and bearing *** method uses the optimised vibration parameters and a simple Artificial Neural Network(ANN)-based machine Learning(mL)model from the earlier *** model is initially developed,tested and validated on an experimental rotating rig operating at a speed above 1st critical *** proposed method and model are then further validated at 2 different operating speeds,one below 1st critical speed and other above 2nd critical *** machine dynamics are expected to be significantly different at these *** highlights the robustness of the proposed 3-Steps method.

关键词： bearing faults fault diagnosis machine learning rotating machines rotor faults vibration analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Natural Convection of a Power-Law Nanofluid in a Square Cavity with a Vertical Fin

引用

Fluid Dynamics & materials Processing 2024年第9期20卷 2091-2108页

作者： Amira m’hadbi mohammed El Ganaoui Haïkel Ben Hamed Amenallah Guizani khalid Chtaibi LERmAB Department of Transition and Energy Efficiency ProfessionsIUT H Poincaréde LongwyUniversity of LorraineLongwy54400France LPT Center for Energy Research and Technologies(Borj Cedria2084)University of Tunis El ManarTunis1068Tunisia LTI Department of Mechanical Engineering and ProductionIUTUniversity of Picardie Jules-VerneAmiens80025France

The behavior of non-Newtonian power-law nanofluids under free convection heat transfer conditions in a cooled square enclosure equipped with a heated fin is investigated *** particular,the impact of nanofluids,composed of water and Al_(2)O_(3),TiO_(2),and Cu nanoparticles,on heat transfer enhancement is *** aim of this research is also to analyze the influence of different parameters,including the Rayleigh number(Ra=10^(4)-10^(6)),nanoparticle volume fraction(φ=0%-20%),non-Newtonian power-law indexes(n=0.6-1.4),and fin dimensions(Ar=0.3,0.5,and 0.7).Streamlines and isotherms are used to depict flow and related heat transfer *** indicate that thermal performance improves with increasing Rayleigh number,regardless of the nanoparticle type or nanofluid rheological *** suggests that the buoyancy force has a significant impact on heat transfer,particularly near the heat *** Nusselt number is more sensitive to variations in Cu nanoparticle volume fractions compared to Al₂O₃and TiO₂.moreover,the average Nusselt numbers for power-law nanofluids with n1)are greater(smaller)than for Newtonian fluids due to the decrease(increase)in viscosity with increasing(decreasing)shear rate,at the same values of Rayleigh number Ra owing to the amplification(attenuation)of the convective ***,the most substantial enhancement is observed with Cu-water shear-thinning nanofluid,where the Nusselt number increases by 136%when changing from Newtonian to shear thinning behavior and by 154.9%when adding 16%nanoparticle volume ***,an even larger increase of 57%in the average Nusselt number is obtained on increasing the fin length from 0.3 to 0.7.

关键词： Heat transfer nanofluid non-Newtonian fluid natural convection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

New soliton solutions of Dual mode Sawada Kotera equation using a new form of modified Kudryashov method and the finite difference method

引用

Journal of Ocean Engineering and Science 2024年第3期9卷 207-215页

作者： khalid K.Ali m.S.mehanna Abdel-Haleem Abdel-Aty Abdul-majid Wazwaz Department of mathematics Faculty of ScienceAl-Azhar UniversityNasr City 11884CairoEgypt Faculty of Engineering MTI UniversityCairoEgypt Department of Physics College of SciencesUniversity of BishaPO Box 344Bisha 61922Saudi Arabia Physics Department Faculty of ScienceAl-Azhar UniversityAssiut 71524Egypt Department of mathematics Saint Xavier UniversityChicagoIL 60655USA

In this article,we suggest a new form of modified Kudryashov’s method(NmK)to study the Dual-mode Sawada Kotera *** know very well that the more the solutions depend on many constants,the easier it is to study the model better by observing the change in the constants and what their impact is on the *** this point of view,we developed the modified Kudryashov method and put it in a general form that contains more than one controllable *** have studied the model in this way and presented figures showing the correctness of what we hoped to reach from the proposed *** addition to the results we reached,they were not sufficient,so we presented an extensive numerical study of this model using the finite differences *** also came up with the local truncation error for the difference scheme is h^(6) k^(2)(1+k^(2)).In addition,the analytical solutions we reached were compared with the numerical solutions,and we presented many forms that show that the results we reached are a clear contribution to this field.

关键词： Soliton solution A new form of analytical method Local truncation error Numerical solutions

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hydrometallurgy two stage process for preparation of (Nd,La,Ce)_(2)O_(3) from end-of-life NimH batteries

引用

Journal of Rare Earths 2024年第2期42卷 415-423,I0007页

作者： Karim Tanji khalid Ouzaouit mohamed Belghiti Isam Lamsayety Hakim Faqir Intissar Benzakour Centre de recherche REmINEX-Groupe mANAGEm MarrakechMorocco

The present work aims to investigate the recovery of light rare earth elements(LREEs) oxides from end-oflife NimH batteries using a hydro metallurgical process followed by effective *** operational leaching parameters such as phosphoric acid concentration,temperature,and the solid-liquid ratio were first optimized by Box-Behnken *** results reveal that under optimum conditions([H_(3)PO_(4)]=2 mol/L,T=80℃,and S/L=1:10 g/mL) the leaching efficiencies of Ni,Co reach 98.1% and99.3%.While La,Ce,and Nd elements remain in the leaching residue as(La,Ce,Nd)PO_(4) with yields of 98.2%,98.6%,and 99.6% for La,Ce,and Nd,***,the(La,Ce,Nd)PO_(4) is leached with HCl acid,then the rare earth oxalate was precipitated using oxalic acid at a pH of 1.8 and then the product was calcined at 800℃ for 2 h in order to synthesize the(Nd,La,Ce)_(2)O_(3).The analysis using scanning electron microscopy(SEm) coupled with energy dispersive X-ray spectroscopy(EDX) confirms the homogeneity of(Nd,La,Ce)_(2)O_(3) particles that have two morphologies,i.e.,flower and sticks with a particle size between 3and 6 μ*** unit cell parameters of(Nd,La,Ce)_(2)O_(3) were calculated after Rietveld refinement of the XRD patterns,in the space group of Fm-3m are a=b=c=0.57921 nm and the volume equal to 0.194322 nm^(3).

关键词： NimH batteries Hydrometallurgical process Leaching Phosphoric acid Box-Behnken Light rare earth oxides

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Physical properties and maximum allowable mass-radius relation of complexity-free compact stellar objects within modified f(R,T)gravity formalism

引用

Chinese Physics C 2024年第7期48卷 273-288页

作者： m.K.Jasim S.K.maurya Abdelghani Errehymy Ali khalid Jassim Kottakkaran Sooppy Nisar Abdel-Haleem Abdel-Aty Department of mathematical and Physical Sciences College of Arts and SciencesUniversity of NizwaNizwa 616Sultanate of Oman Astrophysics Research Centre School of MathematicsStatistics and Computer ScienceUniversity of KwaZulu-NatalPrivate Bag X54001Durban 4000South Africa Electrical Engineering Department College of EngineeringMustansiriyah UniversityBaghdadIraq Department of mathematics College of Science and Humanities in AlkharjPrince Sattam bin Abdulaziz UniversityAl KharjSaudi Arabia Department of Physics College of SciencesUniversity of BishaP.O.Box 344Bisha 61922Saudi Arabia

This paper investigates the physical properties and predicted radii of compact stars generated by the Tolman-IV complexity-free model within the background of modified gravity theory,particularly the f(R,T)-gravity theory,under complexity formalism for a spherically symmetric spacetime proposed by ***[Phys Rev D 97:044010,2018].By solving the resulting set of differential equations,we obtain the explicit forms of the energy-momentum(Em)tensor components,including the density,radial pressure,and tangential *** influence of the parameterχon various physical properties of the star is thoroughly *** model undergoes a series of rigorous tests to determine its physical *** findings indicate that the model exhibits regularity,stability,and a surface with vanishing *** boundary of this surface is determined by carefully selecting the parameter *** complexity method employed in f(R,T)gravity offers an interesting approach for developing astrophysical models that are consistent with observable events as demonstrated by recent *** this regard,we use observational data from the GW190814 event,detected by the LIGO and Virgo observatories,to investigate the validity of the Tolman-IV model in f(R,T)*** analysis includes comparing the model's predictions with the observed characteristics of the compact object involved in the *** addition,data from two-millisecond pulsars,PSR J1614-2230 and PSR J0952-0607,are incorporated to further constrain the theoretical ***,we present a diagram depicting the relationship between the total mass and radius of the compact object candidates for different values ofχ.

关键词： complexity modified gravity compact Stars

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Al^(3+) doped CeO_(2) for proton conducting fuel cells

引用

International Journal of minerals,metallurgy and materials 2024年第10期31卷 2253-2262页

作者： Sarfraz Shahzad Rasool muhammad khalid mAKYousaf Shah Bin Zhu Jung-Sik Kim muhammad Imran Asghar Nabeela Akbar Wenjing Dong Jiangsu Provincial Key Laboratory of Solar Energy Science and Technology/Energy Storage joint Research Center School of Energy and EnvironmentSoutheast UniversityNanjing 210096China School of microelectronics Hubei UniversityWuhan 430062China Sino-French Engineer School/School of General Engineering Beihang UniversityBeijing 100191China Renewable Energy Technologies Group Faculty of Engineering and Natural SciencesTampere UniversityFI-33014Finland

Developing high ionic conducting electrolytes is crucial for applying proton-conducting fuel cell(PCFCs)*** cur-rent study investigates the effect of alumina on the structural,morphological,electrical,and electrochemical properties of CeO_(2).Lattice oxygen vacancies are induced in CeO_(2) by a general doping concept that enables fast ionic conduction at low-temperature ranges(300-500℃)for *** refinement of the X-ray diffraction(XRD)patterns established the pure cubic fluorite structure of Al-doped CeO_(2)(ADC)samples and confirmed Al ions’fruitful integration in the CeO_(2) *** electronic structure of the alumina-doped ceria of the materials(10ADC,20ADC,and 30ADC)has been *** a result,it was found that the best composition of 30ADC-based electrolytes induced maximum lattice oxygen *** corresponding PCFC exhibited a maximum power output of 923 mW/cm^(2)at 500℃.moreover,the investigation proves the proton-conducting ability of alumina-doped ceria-based fuel cells by using an oxide ion-blocking layer.

关键词： proton ceramic fuel cells oxygen vacancies higher fuel cell performance doping fast ions transportation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dosage and utilization of dexamethasone in the management of COVID-19: A critical review

引用

World Journal of Virology 2024年第3期13卷 107-114页

作者： Imran Sethi Asim Shaikh musa Sethi Hira khalid Chohan Sheraz Younus Syed A khan Salim Surani Department of Critical Care medicine Marion General HospitalMarionIN 46952United States Department of medicine Aga Khan UniversityKarachi 74200SindhPakistan Department of medicine Eman SchoolFishersIN 46038United States Department of Internal medicine Dow University of Health ScienceKarachi 74200SindhPakistan Department of Hospital medicine Franciscan HealthIndianapolisIN 46237United States Department of Critical Care medicine Mayo Clinic Health SystemMankatoMN 56001United States Department of medicine and Pharmacology Texas A and M UniversityCollege StationTX 77843United States

BACKGROUND The severe respiratory manifestations observed in severe coronavirus disease 2019(COVID-19)cases are often associated with an excessive inflammatory ***,a synthetic glucocorticoid,exerts its anti-inflammatory effects by inhibiting the transcription of pro-inflammatory genes and suppressing the activity of various immune *** mechanism has implications for mitigating the cytokine storm observed in severe COVID-19 *** on in the pandemic,the Recovery Collaborative working group showed a mortality benefit of using dexamethasone in decreasing mortality in patients with COVID-19 requiring respiratory ***,the optimal dosage of corticosteroids remains *** studies that compare different doses of dexamethasone in COVID-19 exist,but the results are *** To review the latest evidence regarding dosage,safety,and efficacy of dexamethasone in severe *** We followed preferred reporting items for systematic reviews and meta-analysis guidelines.A detailed literature search was conducted across Pubmed,Google Scholar,and medline to include publications up to march *** keywords included“COVID-19”“SARS-CoV-2”“dexamethasone”“corticosteroid”“steroid”and“glucocorticoid”-along with their *** employed the Cochrane Risk of Bias Tool and the Newcastle-Ottawa scale to evaluate the integrity and potential of bias in the included studies.A meta-analysis was conducted using a random-effects model,assessing pooled odds ratios and mean differences,with heterogeneity gauged by the I2 statistic and theχ^(2) *** No statistical differences were found in 28-day all-cause mortality[pooled odds ratio(OR)=1.109,95%CI:0.918-1.340],60-day all-cause mortality(OR=0.873,95%CI:0.744-1.024;I2=47.29%),mean length of hospital stay(mean difference=-0.08 days,95%CI:-0.001 to 0.161)and adverse events(OR=0.877,95%CI:0.707-1.087).CONCLUSION Differing doses of corticosteroids have no clinical implication

关键词： COVID-19 Steroids Corticosteroids Steroid dosage Critical care Corona virus

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：