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Rupture of Liver Hydatid Cyst into Gall Bladder

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Surgical Science 2015年第7期6卷 301-303页

作者： El Mahdi Benkoukous Pierlesky Elion Ossibi Hicham El Bouhadoutti Said ait Laalim Abdelmalek Oussaden khalid Mazaz khalid ait taleb Department of Visceral Surgery Hassan II Teaching Hospital Fes Morocco

Hepatic hydatid cyst is a rare parasitic affection which constitutes a major health problem in countries endemic to hydatidosis. Rupture of hydatid cyst into gallbladder is an exceptional complication first described in 1952 by Atlas and Kamenear. We report the case of a hepatic hydatid cyst rupture into gallbladder in a 31-year-old patient with no history of disease.

关键词： Echinococcus granulosus Hydatid Cyst Gallbladder Rupture Complication

Gastro Intestinal Stromal Tumor: State of the Art through Our Experience of 64 Cases and a Literature Review

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Journal of Cancer Therapy 2020年第5期11卷 265-275页

作者： Saad Slaiki Hicham El Bouhaddouti Abdelmalek Ousadden khalid ait taleb El Bachir Benjelloun Visceral Surgery Department CHU Hassan II Fes Morocco

Gastrointestinal stromal tumors are rare. They are a subject of controversy. We have reported 64 cases of gastrointestinal stromal tumor diagnosed in the surgery department of CHU Hassan II of FES between January 2014 and December 2018. The study involved 64 patients (34 men and 30 women) with an average age of 56. The circumstances of findings were dominated by abdominal pain (48 cases), vomiting 16 case followed by transit disorder with 9 cases. The tumor locations were mainly the stomach (n = 31), the small intestine (n = 28), the duodenum (n = 3), and the colon (n = 2). Ultrasound, endoscopy and CT were the main additional tests to detect tumor syndrome. 55 patients were treated by complete surgical excision. Tumor size ranged from 4cm to 18cm. Histologically, the spindle cell type was predominant in 88.91% of cases;epithelioid type was present in 7.81% of cases, while the mixed type was found in 3.6%. The analysis of the expression of CD 117 marker was present in 95.31%, while immunostaining with this marker returned negative in 3 cases;i.e. 5% whose c-kit was positive. Imatinib was indicated in 44 patients (63.60%), with 9 indications for metastatic tumor. As a neoadjuvant, imatinib was indicated in 5 patients, with remission in 28 patients (50.9%), stabilization in 4 patients (7.2%), 2 cases of tumor recurrence and 7 cases of death.

关键词： Stromal Tumor Imatinib Surgery GIST

Retroperitoneal Smooth Muscle Tumor of Uncertain Malignant Potential (STUMP): Case Report

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Surgical Science 2016年第12期7卷 528-531页

作者： Moussa Sylla Pierlesky Elion Ossibi Issam Yazough Eddy Oleko Ekuke El Bachir Benjelloun Said ait Laalim khalid Mazaz khalid ait taleb Visceral Surgery Department Hassan II University Hospital Fez Morocco

Retro peritoneal smooth muscle tumors of uncertain malignant potential (STUMP) are rare and often misdiagnosed as leiomyosarcoma. We hereby report the case of a retroperitoneal STUMP diagnosed on a surgical specimen i... 详细信息

关键词： Smooth Muscle Tumors Uncertain Malignant Potential Retroperitoneal

Annular pancreas producing duodenal obstruction: A case report

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Open Journal of Gastroenterology 2013年第3期3卷 202-204页

作者： Abdesslam Bouassria Hicham Elbouhaddouti Ouadii Mouaqit El Bachir Benjelloun Abdelmalek Ousadden khalid Mazaz khalid ait taleb Department of General Surgery “A” University Hospital Hassan II Fez Morocco Department of General Surgery “B” University Hospital Hassan II Fez Morocco

Annular pancreas is a rare congenital anomaly characterized by the presence of ectopic pancreatic tissue surrounding the duodenum. This malformation is usually asymptomatic in adults, but can manifests as pancreatitis, duodenal stenosis, or duodenal or gastric ulceration. We report the case of a young patient of 18 years old hospitalized for epigastric pain and vomiting, in whom radiological investigations showed an annular pancreas. At operation, a complete obstruction of the duodenum between its first and second parts was found, caused by an annular pancreas. No other congenital anomaly of the intra abdominal organs was noted. A gastroenterostomy was performed. Both the rarity of this congenital abnormality and its successful correction by surgical means have prompted us to make the following presentation.

关键词： Annular Pancreas Duodenal Stenosis Gastroenterostomy

Hemobilia Due to an Iatrogenic Arteriobiliary Fistula Complicating Laparoscopic Cholecystectomy: A Case Report

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Open Journal of Gastroenterology 2014年第6期4卷 275-278页

作者： Hicham El Bouhaddouti khalid Mazine Abdesslam Bouassria Ouadii Mouaqit Elbachir Benjelloun Abdelmalek Ousadden khalid ait taleb Department of Visceral Surgery Faculty of Medicine and Pharmacy of Fez University Hospital Hassan II—Fes Sidi Mohamed Ben Abdellah University Fez Morocco

Hemobilia is the result of a pathological communication between bile duct and intra or extrahepatic vessel. 40% to 60% of the haemobilia cases are Iatrogenic, and the other causes are either vascular malformations or hepatic blunt trauma. We describe the case history of a patient in which laparoscopic cholecystectomy was complicated 3 months later by massive hemobilia. The cause of haemorrhage was a fistula between the principal bil duct and the right hepatic artery. This complication was successfully managed by surgery and angiographic embolization with full recovery of the patient.

关键词： Hemobilia Gastrointestinal Bleeding Arteriography

Squamous Cell Carcinoma of the Pancreas

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Surgical Science 2014年第10期5卷 487-489页

作者： Pierlesky Elion Ossibi Issam Yazough Amal Bennani KarimIbn Majdoub Imane Toughrai Said ait Laalim Abdelmalek Ousadden Laila Chbani khalid Mazaz khalid ait taleb Visceral Surgery Department Hassan II University Hospital Fez Morocco Anatomy and Pathological Cytology Department Hassan II University Hospital Fez Morocco

Exocrine pancreatic tumors are dominated by adenocarcinomas that have a poor prognosis. Squamous Cell Carcinoma of the pancreas is rare. We report a case of squamous cell carcinoma of the pancreas in a 75-year-old pat... 详细信息

关键词： Carcinoma Squamous Cell Pancreas

Pseudotumoral Colic Tuberculosis: A Rare Pathological Entity

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Surgical Science 2016年第12期7卷 522-527页

作者： Eddy Oleko Ekuke Pierlesky Elion Ossibi El Mahdi Benkoukous Moussa Sylla Boubacar Efared Laila Chbani Abdelmalek Ousadden khalid Mazaz khalid ait taleb Visceral Surgery Department Hassan II University Hospital Fez Morocco Anatomy and Pathological Cytology Department Hassan II University Hospital Fez Morocco

Colic tuberculosis is rare even in countries endemic to Mycobacterium spp. Its incidence seems to be increasing over the last decade. Presentation in the form of abdominal mass is exceptional and often misdiagnosed as gastrointestinal tumor. The possibility of a colic involvement of this infection needs to be considered given the broad spectrum of clinical manifestations of TB infection. We present a case of pseudo colic tuberculosis in a 58-year-old patient with no history of disease.

关键词： Colon Tuberculosis Pseudo-Tumor

Fasciitis on Abdominal Craniectomy Implantation

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Surgical Science 2014年第10期5卷 479-482页

作者： Pierlesky Elion Ossibi Salima Rezzouk Ibrahima Berete KarimIbn Majdoub Imane Toughrai Said ait Laalim Abdelmalek Ousadden Mohammed Chaoui El Faiz khalid Mazaz khalid ait taleb Visceral Surgery Department Hassan II University Hospital Fez Morocco Neurosurgery Department Hassan II University Hospital Fez Morocco

Necrotizing fasciitis is an infection of the skin and deep subcutaneous tissue. It is caused by bacteria (group A streptococcus), but may also be idiopathic ora secondary complication of surgery. We report a case of n... 详细信息

关键词： Fasciitis Craniectomy Abdominal Implantation

Primary Anorectal Melanomas Interest of Targeting C-KIT in Two Cases from a Series of 11 Patients

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Journal of Cancer Therapy 2014年第3期5卷 225-230页

作者： Karima Oualla Nawfel Mellas Fatimazahra El’mrabet Samia Arifi Afaf Amarti khalid ait taleb Siham Tizniti Omar Elmesbahi Department of Medical Oncology Hassan II University Hospital Fez Morocco Department of Pathology Hassan II University Hospital Fez Morocco Department of Radiology Hassan II University Hospital Fez Morocco Department of Visceral Surgery Hassan II University Hospital Fez Morocco

Background: The anorectal location of melanomas is extremely rare (1% - 3% of all melanomas), and the prognosis remains poor because of the aggressiveness and the high metastatic potential of those tumors. The discovery that the KIT oncogene may be aberrantly activated in a subset of patients with anorectal melanoma creates a realm of possibility for the development of targeted molecular therapy. Aim: to show the epidemiologic, clinico-radiological, histological features and treatment management especially in patients with over-expression of C-KIT treated by Imatinib. Methods: It is a retrospective study conducted in the department of medical oncology at Hassan II University Hospital between January 2007 and January 2012, including all patients with histologically proven melanoma of the anorectal area. Results: 11 cases were collected, with slight female predominance. Nine patients were metastatic at the moment of diagnosis, and only two with local stage, but evolution was marked by local and distant recurrence less than 12 months after abdo-minoperineal resection. First line of chemotherapy was based mainly on paclitaxel, carboplatine and dacarbazine. Response was modest with only 3 partial responses, 4 patients with disease stability, and 4 patients with disease progression. Two patients, with over expression of C-KIT, received Imatinib as second line of treatment with significant improvement of symptoms and radiological response reaching 50%. Seven patients died with a median survival of 11 months from diagnosis to the date of death. Conclusion: Primary anorectal melanomas are very rare, with high aggressiveness and poor prognosis. Treatment management is still a big challenge given to the modest efficacy of conventional chemotherapy. Better understanding of carcinogenesis and signaling pathways will allow development of new targeted therapies.

关键词： Melanoma Anorectal Area Surgery Chemotherapy C-KIT Imatinib