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Rock Strength Estimation Using Several Tree-Based ML Techniques

Computer Modeling in Engineering & Sciences 2022年第12期133卷 799-824页

作者： Zida Liu Danial Jahed Armaghani Pouyan Fakharian Diyuan Li Dmitrii Vladimirovich Ulrikh Natalia Nikolaevna Orekhova khaled mohamed khedher School of Resources and Safety Engineering Central South UniversityChangsha410083China Department of Urban Planning Engineering Networks and SystemsInstitute of Architecture and ConstructionSouth Ural State UniversityChelyabinsk454080Russia Faculty of Civil Engineering Semnan UniversitySemnan35131-19111Iran Department of Geology Mine Surveying and Mineral ProcessingNosov Magnitogorsk State Technical UniversityMagnitogorsk455000Russia Department of Civil Engineering College of EngineeringKing Khalid UniversityAbha61421Saudi Arabia Department of Civil Engineering High Institute of Technological StudiesMrezgua University CampusNabeul8000Tunisia

The uniaxial compressive strength(UCS)of rock is an essential property of rock material in different relevant applications,such as rock slope,tunnel construction,and *** takes enormous time and effort to obtain the UCS values directly in the ***,an indirect determination of UCS through conducting several rock index tests that are easy and fast to carry out is of interest and *** study presents powerful boosting trees evaluation framework,i.e.,adaptive boosting machine,extreme gradient boosting machine(XGBoost),and category gradient boosting machine,for estimating the UCS of *** hammer rebound number,P-wave velocity,and point load index were chosen as considered factors to forecast UCS values of sandstone *** diagrams and five regression metrics,including coefficient of determination(R2),root mean square error,mean absolute error,variance account for,and A-20 index,were used to evaluate and compare the performance of these boosting *** results showed that the proposed boosting trees are able to provide a high level of prediction capacity for the prepared *** particular,itwas worth noting that XGBoost is the best model to predict sandstone strength and it achieved 0.999 training R^(2) and 0.958 testing R^(2).The proposed model had more outstanding capability than neural network with optimization techniques during training and testing *** performed variable importance analysis reveals that the point load index has a significant influence on predicting UCS of sandstone.

关键词： Uniaxial compressive strength rock index tests machine learning techniques boosting tree

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Influence of Recycling Waste Glass as Fine Aggregate on the Concrete Properties

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Journal of Renewable Materials 2023年第6期11卷 2925-2940页

作者： Rafal A.Hadi Suhad M.Abd Hadee Mohammed Najm Shaker Qaidi Moutaz Mustafa A.Eldirderi khaled mohamed khedher Department of Civil Engineering Bilad Alrafidain University CollegeDiyala32001Iraq Department of Civil Engineering College of EngineeringUniversity of DiyalaDiyala32001Iraq Department of Civil Engineering Zakir Husain Engineering CollegeAligarh Muslim UniversityAligarh202002India Department of Civil Engineering College of EngineeringUniversity of DuhokDuhok42001Iraq Department of Civil Engineering College of EngineeringNawroz UniversityDuhok42001Iraq Department of Chemical Engineering College of EngineeringKing Khalid UniversityAbha61421Saudi Arabia Department of Civil Engineering College of EngineeringKing Khalid UniversityAbha61421Saudi Arabia Department of Civil Engineering High Institute of Technological StudiesMrezgua University CampusNabeul8000Tunisia

Recent years have witnessed an increase in the quantity of waste glass(WG)across the *** the fine aggregate with WG is one of the steps toward preserving the natural resources of the environment and creating low-cost *** present study is concerned with replacing fine aggregates with glass powder(GP)at(0%,15%,30%,and 50%).It has studied the fresh and hardened properties(compressive strength,tensile strength,hardened density,and slump)for all the mentioned percent *** findings have shown that all mixtures containing GP gave acceptable slump results within the design limits(2–5 cm)according to ACI standard *** has been observed that increasing the proportion of GP led to a decrease in the weight of ***,replacing GP with sand by 30%has led to an increase in the compressive strength by about 2.4%and 12.45%,and the tensile strength by about 2.5%and 26.54%at 7-and 28-d,respectively in comparison to normal concrete.

关键词： Sustainable concrete glass powder fine aggregate partial replacement

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A coal rib monitoring study in a room-and-pillar retreat mine

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International Journal of Mining Science and Technology 2021年第1期31卷 127-135页

作者： Gamal Rashed khaled mohamed Robert Kimutis GCB/PMRD//NIOSH/CDC PittsburghPA 15236USA

The National Institute for Occupational Safety and Health(NIOSH)conducted a comprehensive monitoring program in a room-and-pillar mine located in Southern *** deformation and the stress change in an instrumented pillar were monitored during the progress of pillar retreat mining at two sites of different geological conditions and depths of *** main objectives of the monitoring program were to better understand the stress transfer and load shedding on coal pillars and to quantify the rib deformation due to pillar retreat mining;and to examine the effect of rib geology and overburden depth on coal rib *** instrumentation at both sites included pull-out tests to measure the anchorage capacity of rib bolts,load cells mounted on rib bolts to monitor the induced loads in the bolts,borehole pressure cells(BPCs)installed at various depths in the study pillar to measure the change in vertical pressure within the pillar,and roof and rib extensometers installed to quantify the vertical displacement of the roof and the horizontal displacement of the rib that would occur during the retreat mining *** outcome from the monitoring program provides insight into coal pillar rib support optimization at various depths and geological ***,this study contributes to the NIOSH rib support database in U.S coal mines and provides essential data for rib support design.

关键词： Coal rib performance Coal rib design Coal rib monitoring Coal rib failure Load transfer Retreat mining

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Experimental and Numerical Analyses of the Pull-out Response of a Steel Post/Bovine Bone Cementless Fixation

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Journal of Bionic Engineering 2012年第4期9卷 501-507页

作者： khaled Gammoudi mohamed Kharrat Maher Dammak National Engineering School of Sfax Electromechanical Systems Laboratory Soukra road km 3.5 B.P. 1173 3038 Sfax Tunisia Higher Institute of Technological Studies of Gafsa University campus Sidi Ahmed Zarrouk 2112 Gafsa Tunisia Faculty of Sciences of Gafsa University campus Sidi Ahmed Zarrouk 2112 Gafsa Tunisia Preparatory Institute for Engineering Studies of Sfax Menzel Chaker Road Km 0.5 B.P. 1172 3018 Sfax Timisia

Effect of initial interference fit on pull-out strength in cementless fixation between bovine tibia and smooth stainless steel post was investigated in this study. Compressive behavior of bovine spongious bone was studied using mechanical testing in order to evaluate the elastic-plastic properties in different regions of the proximal tibia. Friction tests were carried out in the aim to evaluate the friction behavior of the contact between bovine spongious bone and stainless steel. A cylindrical stainless steel post inserted in a pre-drilled bovine tibia with an initial interference fit was taken as an in vitro model to assess the contribution of post fixation to the initial stability of the Total Knee Arthroplasty （TKA） tibial component. Pull-out experiments were carried out for different initial interference fits. Finite Element Models （FEM） using local elastic-plastic properties of the bovine bone were developed for the analysis of the experimental ultimate pull-out force results. At the post/bone interface, Coulomb friction was considered in the FEM calculations with pressure-dependent friction coefficient. It was found that the FEM results of the ultimate force are in good agreement with the experimental results. The analysis of the FEM interfacial stresses indicates that the micro-slip initiation depends on the local bone properties.

关键词： total knee arthroplasty bovine bone/steel post fixation interference fit puU-out strength FEM

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Calculus bovis in hepatocellular carcinoma:Tumor molecular basis,Wnt/β-catenin pathway role,and protective mechanism

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World Journal of Gastroenterology 2024年第35期30卷 3959-3964页

作者： khaled mohamed mohamed Koriem Department of Medical Physiology Medical Research and Clinical Studies InstituteNational Research CentreGiza 12622Egypt

In this editorial,we comment on the recent article by Huang et *** editorial focuses specifically on the molecular mechanisms of hepatocellular carcinoma(HCC),mechanism of Wnt/β-catenin pathway in HCC,and protective mechanism of Calculus bovis(CB)in *** cancer is the fourth most common cause of cancer-related deaths *** most prevalent kind of primary liver cancer,HCC,is typically brought on by long-term viral infections(hepatitis B and C),non-alcoholic steatohepatitis,excessive alcohol consumption,and other conditions that can cause the liver to become chronically inflamed and *** is a wellknown traditional remedy in China and Japan and has been used extensively to treat a variety of diseases,such as high fever,convulsions,and *** in lipid metabolism,cholesterol metabolism,bile acid metabolism,alcohol metabolism,and xenobiotic detoxification lead to fatty liver disease and liver ***,which is a tricarboxylic acid cycle intermediate,is vital to energy production and mitochondrial *** is also thought to be a signaling molecule in metabolism and in the development and spread of liver *** Wnt/β-catenin pathway is made up of a group of proteins that are essential for both adult tissue homeostasis and embryonic *** is frequently caused by the dysregulation of the Wnt/β-catenin signaling *** HCC liver carcinogenesis,Wnt/β-catenin signaling is activated by the expression of downstream target *** between the liver and the gut exists via the portal vein,biliary tract,and systemic ***"gutliver axis"controls intestinal *** of the main factors contributing to the development,progression,and treatment resistance of HCC is the abnormal activation of the Wnt/β-Catenin signaling ***,understanding this pathway is essential to treating *** ingredients of CB,particularly oleanolic acid,ergosterol,and ursolic acid,have anti-p

关键词： Hepatocellular carcinoma MicroRNAs Wnt/β-catenin pathway Calculus bovis Apoptosis

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Lipidome is lipids regulator in gastrointestinal tract and it is a life collar in COVID-19:A review

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World Journal of Gastroenterology 2021年第1期27卷 37-54页

作者： khaled mohamed mohamed Koriem Medical Physiology Department Medical Research DivisionNational Research CentreDokki 12622CairoEgypt

The term lipidome is mentioned to the total amount of the lipids inside the biological *** lipid enters the human gastrointestinal tract through external source and internal *** absorption pathway of lipids in the gastrointestinal tract has many ways;the 1st way,the lipid molecules are digested in the lumen before go through the enterocytes,digested products are re-esterified into complex lipid *** 2nd way,the intracellular lipids are accumulated into lipoproteins(chylomicrons)which transport lipids throughout the whole *** lipids are re-synthesis again inside the human body where the gastrointestinal lipids are:(1)Transferred into the endoplasmic reticulum;(2)Collected as lipoproteins such as chylomicrons;or(3)Stored as lipid droplets in the *** lipids play an important role in many stages of the viral replication *** specific lipid change occurs during viral infection in advanced viral replication *** are 47 lipids within 11 lipid classes were significantly disturbed after viral *** virus connects with blood-borne lipoproteins and apolipoprotein E to change viral *** viral interest is cholesterol-and lipid raft-dependent *** conclusion,lipidome is important in gastrointestinal fat absorption and coronavirus disease 2019(COVID-19)infection so lipidome is basic in gut metabolism and in COVID-19 infection success.

关键词： Lipidome Gastrointestinal tract Fat metabolism COVID-19 Viral infection Future therapy

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Multiple sclerosis: New insights and trends

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Asian Pacific Journal of Tropical Biomedicine 2016年第5期6卷 429-440页

作者： khaled mohamed mohamed Koriem Department of Medical Physiology Medical Research DivisionNational Research Centre

Multiple sclerosis(MS) is the most famous autoimmune disease attacking the central nervous system. It attacks people from age 20–50 years old and the females' attacks double than males' attacks. MS is an autoimmune disease affecting principally the central nervous system that cause nerve sheath demyelination followed by axon damage and paralysis. MS symptoms include muscle weakness, weak reflexes, muscle spasm, difficult in move, miss-coordination and unbalance with others. There are many factors may be responsible for MS: microbial, viral, smoking, stress, environmental toxins, contaminated diet, and gout. MS is wide spread in the populations in North Europe and this related to lack of vitamin D due to decrease of sunlight exposure. MS biomarkers include nitric oxide, interleukin-6, nitric oxide synthase, fetuin-A and osteopontin. MS is not a genetic disease where MS occurs when human leukocyte antigen system related genes are changed in chromosome 6. The physiology of MS is monitored by activation of immuneinflammatory, oxidative, and nitrosative stress pathways. MS is including two main steps:(1) myelin sheath destruction and formation of lesions and,(2) inflammation. Four types of MS can be distinguished: relapsing-remitting, primary progressive, secondary progressive and progressive relapsing. Nine treatments have been accepted for relapsingremitting MS type: interferon b-1a, interferon b-1b, mitoxantrone, natalizumab, glatiramer acetate, fingolimod, dimethyl fumarate, teriflunomide, and alemtuzumab, however,the only treatment used is mitoxantrone for progressive MS but many of MS treatments side effects are recorded. Complementary treatments also used in MS treatments such as:vitamin D, Yoga, medicinal plants, oxygen therapy, acupuncture and reflexology.

关键词： Multiple sclerosis Diagnosis Genetics Physiology Treatments

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A lipidomic concept in infectious diseases

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Asian Pacific Journal of Tropical Biomedicine 2017年第3期7卷 265-274页

作者： khaled mohamed mohamed Koriem Department of Medical Physiology Medical Research Division National Research CentreDokki Cairo Egypt

Infectious diseases resemble a great threat to the human health according to World Health Organization where about 17% of all deaths(z9.2 million deaths) in 2013 recorded are related to infectious diseases. The pathogenic microorganisms such as bacteria, viruses,fungi and parasites are the principle causes of infectious diseases. Ebola, AIDS, dengue,hepatitis, malaria, tuberculosis and schistosomiasis are among 216 infectious diseases found where the immunity represents the first line defense in infection. Lipidomic includes examination of different biological lipids in the biological cell. The lipidomic research covers all aspects of individual lipid molecule including its structure, function,connection with other cell constituents such as protein, lipid, and metabolite in both health and disease conditions. Details of cell biology obtained from different pathogens(viruses, bacteria, and parasites) provide a great data on molecular structure of hostpathogen relation and consequently on infection process. The lipids here play a very important role in many processes involved in host-pathogen relations. The role of lipid in host-pathogen link includes many processes in(1) structural host constituents,(2) host recognition,(3) intracellular transferring, and(4) energy and resource homeostasis during pathogen duplication. There are many lipid phosphatases, kinases, and lipases molecules that greatly involved in these processes and controlling pathogen expression and infection progress. The cell lipid metabolism depends on an adequate energy stores that push the infection to be accelerated and disease symptoms to be appeared. Consequently, future lipidomics studies are the basic for detecting the lipid role in host-pathogen relations which help in therapy advances and biomarkers development.

关键词： Lipidomics Virus Bacteria Parasite Membrane trigger

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Protective effect of natural products and hormones in colon cancer using metabolome:A physiological overview

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Asian Pacific Journal of Tropical Biomedicine 2017年第10期7卷 957-966页

作者： khaled mohamed mohamed Koriem Department of Medical Physiology Medical Research DivisionNational Research CentreDokkiCairoEgypt

Globally, the third cause of males cancer and the fourth cause of females cancer is colon cancer(CC). In Egypt, high CC percentage occurs in children and in individuals below 40 years of age. The complete loss of biological enzyme function is the main cause of CC and consequently CC increased in smoking and pollution exposure. The aim of this review is to focus on the application of metabolome as a physiological tool that can play an important role in preventing CC incidence by natural products and hormones. The dietary factors, intestinal micro-flora and endogenously produced metabolites are the main three causes that produce free radicals in the colon. A correlation occurs between the enzyme activity and CC polymorphisms or property. Nowadays metabolome is applied with the progress of different analytical methods, data bases and tools for cancer predication and stimulation especially in CC cases. Metabolism is defined as intracellular chemical reactions that produce chemical substances and energies sustaining life. Metabolic pathway networks are also composed of links that are defined as transformation of chemical structures between two metabolites and an enzyme reaction. The most important advantage of metabolome is its ability to analyze metabolites from any source, regardless of origin, where the application of liquid chromatography combined with mass spectra in metabolome analysis to a series of cancer cell lines that were progressively more tumorigenic due to the induction of 1,2,3 or 4 oncogenes to cell lines could be a metabolome example application. In conclusion, natural products and hormones are very important in preventing CC in humans and animal models where both natural products and hormones play a significant and important effect in regulating physiological process especially in CC cases. In this situation, metabolome must increase in its application in the future for the diagnosis of CC cases.

关键词： Colon cancer Metabolome Physiology Natural products Hormones

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Loading characteristics of mechanical rib bolts determined through testing and numerical modeling

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International Journal of Mining Science and Technology 2020年第1期30卷 17-24页

作者： khaled mohamed Gamal Rashed Zorica Radakovic-Guzina Centers for Disease Control National Institute for Occupational Safety and HealthPittsburghPA 15236USA ITASCA Consulting Group MinneapolisMN 55401USA

Underground coal mines use mechanical bolts in addition to other types of bolts to control the rib deformation and to stabilize the yielded coal *** research has been conducted to understand the performance of the mechanical bolts in coal *** from the National Institute for Occupational Safety and Health(NIOSH)conducted this work to understand the loading characteristics of mechanical bolts(stiffness and capacity)installed in coal ribs at five underground coal *** pull-out tests were performed in this study to define the loading characteristics of mechanical rib *** installation torques were applied to the tested bolts based on the strength of the coal seam.A typical tri-linear load-deformation response for mechanical bolts was obtained from these *** was found that the anchorage capacity depended mainly on the coal *** for modeling mechanical bolts have been developed using the tri-linear load-deformation *** outcome of this research provides essential data for rib support design.

关键词： Coal rib Mechanical bolt Conventional bolt Tension bolt Point-anchored bolt Rib support Pull-out test Numerical modeling FLAC3D

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