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The Ananthakrishna Model under Non-synchronous Perturbation

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Acta Mathematicae Applicatae Sinica 2024年第4期40卷 1078-1097页

作者： Yi-wen TAO Sue ann CAMPBELL Jing-li REN School of Mathematics and Statistics Zhengzhou UniversityZhengzhou 450001China Department of Applied Mathematics University of WaterlooWaterloo N2L3G1Canada

The Ananthakrishna model,seeking to explain the Portevin-Le Chatelier effect,is studied with or without non-synchronous *** the unperturbed model,Bogdanov-Takens bifurcation and zeroHopf bifurcation are *** the perturbed model,rich dynamical behaviors are given by researching the Poincarémap,including solutions of different periods,quasi-periodic solutions,chaotic solutions,and ***,an augmented temperature-dependent perturbation amplitude induces a transition from non-serrated to serrated flow on the stress-time ***,on the stress-strain curve,the phenomenon of repeated yielding diminishes with an increase in the value of a temperature-dependent parameter,while it persists with an increase in the value of a temperature-independent *** analysis sheds light on the factors exerting the most significant influence on dislocation density.

关键词： Ananthakrishna model serrations non-synchronous perturbation attractor bifurcation

Probing the Galactic Halo with RR Lyrae *** Radial Velocity Curve Templates of RRc Stars

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Research in Astronomy and Astrophysics 2024年第7期24卷 118-134页

作者： Yue Huang Min Fang Gaochao Liu Xianzhong Zheng Sarah ann Bird Yang Huang Jianrong Shi Jiangtao Wang Huawei Zhang Haijun Tian Haotong Zhang College of Science China Three Gorges UniversityYichang 443002China Center for Astronomy and Space Sciences China Three Gorges UniversityYichang 443002China Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China School of Astronomy and Space Science University of Science and Technology of ChinaHefei 230026China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China CAS Key Laboratory of Optical Astronomy National Astronomical ObservatoriesBeijing 100101China Department of Astronomy School of PhysicsPeking UniversityBeijing 100871China Kavli Institute for Astronomy and Astrophysics Peking UniversityBeijing 100871China School of Sciences Hangzhou Dianzi UniversityHangzhou 310018China

We present radial velocity(RV)curve templates of RR Lyrae first-overtone(RRc)stars constructed with the Mg I b triplet and Hαlines using time-domain Medium-Resolution Survey spectra of seven RRc stars from Large Sky Area Multi-Object Fiber Spectroscopic Telescope(LAMOST)Data Release ***,we derive the relation between the stellar RV curve amplitudes and g-band light curve amplitudes from Zwicky Transient Facility(ZTF)public *** those RRc stars without ZTF g-band light curves,we provide the conversions from the light curve amplitudes in ZTF r-and i-bands,Gaia G-band,and V-band from the all-Sky Automated Survey for Supernovae to those in ZTF *** validate our RV curve templates using the RRc star SV Scl and find the uncertainties of systemic RV are less than 2.11 km s~(-1)and 6.08 km s~(-1)based on the Mg I b triplet and Hαlines,*** cal.ulate the systemic RVs of 30 RRc stars using the RV curve templates constructed with the Mg I b triplet and Hαlines and find the systemic RVs are comparable with each *** RV curve template will be particularly useful for obtaining the systemic RV of RRc using the LAMOST spectroscopy.

关键词： stars variables RR Lyrae-Stars-techniques radial velocities

Subwavelength hybrid plasmonic structures for nonlinear nanophotonics

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Light(Science & Applications) 2021年第3期10卷 307-309页

作者： ann-Katrin u.Michel Optical Materials Engineering Laboratory Department of Mechanical and Process EngineeringETH ZurichZurichSwitzerland

Plasmonic structures made of a semiconductor-insulator-metal hybrid provide efficient routes for second-harmonic and sum-frequency generation in sub-micrometer structures,which ultimately may boost on-chip integrated ... 详细信息

关键词： structures nonlinear plasmon

Panel Discussion on“Development Trends of Computer Science in the New Era”

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计算机教育 2024年第3期 26-29页

作者： Andrew Yao Nancy M.Amato ann Copestake Sukyoung Ryu Yike Guo Yaqin Zhang Institute for Interdisciplinary Information Sciences Tsinghua UniversityBeijing100084China Department of Computing University of IllinoisUrbana61801U.S Department of Computer Science and Technology University of CambridgeCambridgeCB30FDUK Korea Advanced Institute of Science and Technology(KAIST) Yuseong-gu Daejeon34141Korea Hong Kong university of Science and Technology Hong Kong999077China Institute for AI Industry Research(AIR) Tsinghua UniversityBeijing100084China

At the panel session of the 3rd Global Forum on the Development of Computer Science,attendees had an opportunity to deliberate recent issues affecting computer science departments as a result of the recent growth in the field.6 heads of university computer science departments participated in the discussions,including the moderator,Professor Andrew *** first issue was how universities are managing the growing number of applicants in addition to swelling class *** approaches were suggested,including increasing faculty hiring,implementing scalable teaching tools,and working closer with other departments through degree programs that integrate computer science with other *** second issue was about the position and role of computer science within broader *** generally agreed that all fields are increasingly relying on computer science techniques,and that effectively disseminating these techniques to others is a key to unlocking broader scientific progress.

关键词： Development trends Computer science

RNA m^(6)A reader YTHDF2 facilitates precursor miR-126 maturation to promote acute myeloid leukemia progression

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Genes & Diseases 2024年第1期11卷 382-396页

作者： Zheng Zhang Keren Zhou Li Han Andrew Small Jianhuang Xue Huilin Huang Hengyou Weng Rui Su Brandon Tan Chao Shen Wei Li Zhicong Zhao Ying Qing Xi Qin Kitty Wang Keith Leung Mark Boldin Chun-Wei Chen David ann Zhijian Qian Xiaolan Deng Jianjun Chen Zhenhua Chen Department of Systems Biology Beckman Research Institute of City of HopeMonroviaCA 91016USA Irell and Manella Graduate School of Biological Sciences Beckman Research Institute of City of HopeDuarteCA 91010USA Gehr Family Center for Leukemia Research City of HopeDuarteCA 91010USA Sun Yat-sen university Cancer Center State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangzhouGuangdong 510060China Guangzhou Laboratory GuangzhouGuangdong 510005China Bioland Laboratory GuangzhouGuangdong 51005China Department of Liver Surgery Renji HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China Department of Diabetes Complications and Metabolism Beckman Research Institute of City of HopeDuarteCA 91010USA Department of Biochemistry and Molecular Biology University of FloridaGainesvilleFL 32603USA Tongji Hospital Affiliated to Tongji university Frontier Science Center for Stem Cell ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China School of Pharmacy China Medical UniversityShenyangLiaoning 110001China

As the most common internal modification of mRNA,Ne-methyladenosine(m^(6)A)and its regulators modulate gene expression and play critical roles in various biological and patholog-ical processes including *** was reported previously that m^(6)A methyltransferase(writer),methyltransferase-like 3(METTL3)adds m^(6)A in primary microRNAs(pri-miRNAs)and fa-cilitates its processing into precursor miRNAs(pre-miRNAs).However,it is unknown whether m^(6)A modification also plays a role in the maturation process of pre-miRNAs and(if so)whether such a function contributes to ***,we found that YTHDF2 is aberrantly overexpressed in acute myeloid leukemia(AML)patients,especially in relapsed patients,and plays an onco-genic role in ***,YTHDF2 promotes expression of miR-126-3p(also known as miR-126,as it is the main product of precursor miR-126(pre-miR-126)),a miRNA that was reported as an oncomiRNA in AML,through facilitating the processing of pre-miR-126 into mature ***,YTHDF2 recognizes m^(6)A modification in pre-miR-126 and recruits AGO2,a regulator of pre-miRNA processing,to promote the maturation of ***2 posi-tively and negatively correlates with miR-126 and miR-126's downstream target genes,respec-tively,in AML patients,and forced expression of miR-126 could largely rescue YTHDF2/Ythdf2 depletion-mediated suppression on AML cell growth/proliferation and leukemogenesis,indi-cating that miR-126 is a functionally important target of YTHDF2 in ***,our studies not only reveal a previously unappreciated YTHDF2/miR-126 axis in AML and highlight the ther-apeutic potential of targeting this axis for AML treatment,but also suggest that m^(6)A plays a role in pre-miRNA processing that contributes to tumorigenesis.

关键词： AML miR-126 N^(6)-methyladenosine Pre-miRNA maturation YTHDF2

Transcriptome analysis of sugar beet root maggot （Tetanops myopaeformis） genes modulated by the Beta vulgaris host

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Insect Science 2018年第2期25卷 222-234页

作者： Haiyan Li ann C. Smigocki uSDA-ARS Molecular Plant Pathology Laboratory Beltsville Maryland US

Sugar beet root maggot （SBRM, Tetanops myopaeformis von R6der） is a major but poorly understood insect pest of sugar beet （Beta vulgaris L.）. The molecular mecha- nisms underlying plant defense responses are well documented, however, little information is available about complementary mechanisms for insect adaptive responses to overcome host resistance. To date, no studies have been published on SBRM gene expression pro- filing. Suppressive subtractive hybridization （SSH） generated more than 300 SBRM ESTs differentially expressed in the interaction of the pest with a moderately resistant （F1016） and a susceptible （F1010） sugar beet line. Blast2GO v. 3.2 search indicated that over 40% of the differentially expressed genes had known functions, primarily driven by fruit fly D. melanogaster genes. Expression patterns of 18 selected EST clones were confirmed by RT-PCR analysis. Gene Ontology （GO） analysis predicted a dominance of metabolic and catalytic genes involved in the interaction of SBRM with its host. SBRM genes function- ing during development, regulation, cellular process, signaling and under stress conditions were annotated. SBRM genes that were common or unique in response to resistant or susceptible interactions with the host were identified and their possible roles in insect responses to the host are discussed.

关键词： Beta vulgaris resistant sugar beet root maggot suppressive subtractivehybridization susceptible transcriptome

On the material dependency of peri-implant morphology and stability in healing bone

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Bioactive Materials 2023年第10期28卷 155-166页

作者： Stefan Bruns Diana Krüger Silvia Galli D.C.Florian Wieland Jorg u.Hammel Felix Beckmann ann Wennerberg Regine Willumeit-Romer Berit Zeller-Plumhoff Julian Moosmann Institute of Metallic Biomaterials Helmholtz-Zentrum HereonMax-Planck-Str.121502GeesthachtGermany university of Malmo Faculty of OdontologyDepartment of ProsthodonticsCarl Gustafs Vag 34Klerken20506MalmoSweden Institute of Materials Physics Helmholtz-Zentrum HereonMax-Planck-Str.121502GeesthachtGermany university of Gothenburg Institute of OdontologyDepartment of ProsthodonticsMedicinaregatan 12 f41390GoteborgSweden

The microstructural architecture of remodeled bone in the peri-implant region of screw implants plays a vital role in the distribution of strain energy and implant *** present a study in which screw implants made from titanium,polyetheretherketone and biodegradable magnesium-gadolinium alloys were implanted into rat tibia and subjected to a push-out test four,eight and twelve weeks after *** were 4 mm in length and with an M2 *** loading experiment was accompanied by simultaneous three-dimensional imaging using synchrotron-radiation microcomputed tomography at 5μm *** deformation and strains were tracked by applying optical flow-based digital volume correlation to the recorded image *** stabilities measured for screws of biodegradable alloys were comparable to pins whereas non-degradable biomaterials experienced additional mechanical ***-implant bone morphology and strain transfer from the loaded implant site depended heavily on the biomaterial *** implants stimulated rapid cal.us formation displaying a consistent monomodal strain profile whereas the bone volume fraction in the vicinity of magnesium-gadolinium alloys exhibited a minimum close to the interface of the implant and less ordered strain *** in our data suggest that implant stability benefits from disparate bone morphological properties depending on the biomaterial *** leaves the choice of biomaterial as situational depending on local tissue properties.

关键词： Biodegradable implant materials Bone mechanical testing Implant stability Synchrotron micro-computed tomography imaging Digital volume correlation

Palaeomagnetic Study on the Precambrian-Cambrian Boundary Candidate Stratotype Section at Meishucun, Yunnan

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Acta Geologica Sinica(English Edition) 1991年第1期65卷 97-108页

作者： Liang Qizhong Fang Wu Rob Van der Voo Yunnan Institute of Geological Science, Kunming,Yunnan Department of Geological Sciences,university of Michigan,ann Arbor, MI.48109-1063, u.S.A. Liu Linqun Yunnan Institute of Geological Scienc Kunming Yunnan China

The Meishucun secton has been recommended as an international candidate stratotype secton of thePrecambrian-Cambrian boundary. The paper deals with the palaeomagnetic study on the section. A total of159 palaeomagnetic samples were successively collected from the platform-facies sequence of carbonates andphosphates at the section. Thermal demagnetization results indicate a great majority of the rocks at the sectionhave been strongly overprinted by recent magnetic field, but 57 samples have preserved remanentmagnetization with antipodal directions (mean D/I=4.2°/ 7.1°, K=9, α_(95) = 6.6°). Baaed on cal.ulation,the location of the palaeomagnetic pole was at 68.8°N and 270.7°E, which is different from any palaeopolesobtained from younger Phanerozoic rocks in South China. The results reveal a polarity zonation which in-cludes at least 9 reversal events. A comparison of China's magnetostratigraphic records with those fromSiberia, Australia and the western u.S.A. shows that all the sections are characterized by frequent polarity re-versals.

关键词： Yunnan Palaeomagnetic Study on the Precambrian-Cambrian Boundary Candidate Stratotype Section at Meishucun

Biomarkers in Barrett's esophagus and esophageal adenocarcinoma:Predictors of progression and prognosis

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World Journal of Gastroenterology 2010年第45期16卷 5669-5681页

作者： Chin-ann J Ong Pierre Lao-Sirieix Rebecca C Fitzgerald MRC Cancer Cell unit Hutchison-MRC Research CentreCambridgeCB20XZUnited Kingdom

Barrett’s esophagus is a well-known premalignant lesion of the lower esophagus that is characterized by intestinal metaplasia of the squamous epithelium. It is clinically important due to the increased risk (0.5% per annum) of progression to esophageal adenocarcinoma (EA), which has a poor outcome unless diagnosed early. The current clinical management of Barrett’s esophagus is hampered by the lack of accurate predictors of progression. In addition, when patients develop EA, the current staging modalities are limited in stratifying patients into different prognostic groups in order to guide the optimal therapy for an individual patient. Biomarkers have the potential to improve radically the clinical management of patients with Barrett’s esophagus and EA but have not yet entered mainstream clinical practice. This is in contrast to other cancers like breast and prostate for which biomarkers are utilized routinely to inform clinical decisions. This review aims to highlight the most promising predictive and prognostic biomarkers in Barrett’s esophagus and EA and to discuss what is required to move the field forward towards clinical application.

关键词： Barrett’s esophagus Esophageal adenocar cinoma Esophageal dysplasia Prognosis