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Surgical outcomes and quality of life following exercise-based prehabilitation for hepato-pancreatico-biliary surgery:A systematic review and meta-analysis

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Hepatobiliary & Pancreatic diseases International 2022年第3期21卷 207-217页

作者： Andy deprato Kevin Verhoeff Kieran Purich Janice Y Kung david L Bigam khal.d z dajani University of Alberta 116 St&85 AveEdmontonAlberta T6G 2R3Canada department of Surgery University of Alberta Hospital8440112 Street NWEdmontonAlberta T6G 2B7Canada John W.Scott Health Sciences Library University of Alberta Hospital8440112 Street NWEdmontonAlberta T6G 2B7Canada department of Surgery Division of General SurgeryHPB Transplant and OncologyUniversity of Alberta Hospital8440112 Street NWEdmontonAlberta T6G 2B7Canada

Background:Hepato-pancreatico-biliary(HPB)patients experience significant risk of preoperative *** assessing preventative prehabilitation in HPB populations are *** systematic review and meta-analysis evaluates outcomes for HPB patients treated with exercise *** sources:A comprehensive search of MEdLINE(via Ovid),Embase(Ovid),Scopus,Web of Science Core Collection,Cochrane Library(Wiley),Pro Quest dissertations,Theses Global,and Google Scholar was conducted with review and extraction following PRISMA *** studies evaluated more than 5 adult HPB patients undergoing≥7-day exercise *** primary outcome was postoperative length of stay(LOS);secondary outcomes included complications,mortality,physical performance,and quality of ***:We evaluated 1778 titles and abstracts and selected 6(randomized controlled trial,n=3;prospective cohort,n=1;retrospective cohort,n=2)that included 957 *** those,536 patients(56.0%)underwent exercise prehabilitation and 421(44.0%)received standard *** in both groups were similar with regards to important demographic *** was associated with a 5.20-day LOS reduction(P=0.03);when outliers were removed,LOS reduction decreased to 1.85 days and was non-statistically significant(P=0.34).Postoperative complications(OR=0.70;95%CI:0.39 to 1.26;P=0.23),major complications(OR=0.83;95%CI:0.60 to 1.14;P=0.24),and mortality(OR=0.67;95%CI:0.17 to 2.70;P=0.57)were *** was associated with improved strength,cardiopulmonary function,quality of life,and alleviated ***:Exercise prehabilitation may reduce LOS and morbidity following HPB *** with well-defined exercise regimens are needed to optimize exercise prehabilitation outcomes.

关键词： Exercise-based prehabilitation Preoperative exercise Hepatobiliary Pancreaticoduodenectomy Hepatic resection Pancreatectomy

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PROSTAGLANdINS: PHARMACOGY, MECHANISM ANd APPLICATIONS IN PEPTIC ULCER dISEASE

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中国临床药理学杂志 1989年第2期 102-117页

作者： Esam z.dajani G.d.Searle and Company Chicago U.S.A.

Prostaglandins(PGs) constitute a family of unsaturated fatty acids witha 20-carbon skeleton. Prostaglandins are found in almost every mammaliancell and are considered locally acting hormones (autocoids). They aresynthesized on demand and subsequently destroyed near the site of theirsynthesis. Since the early 1960’s, increasing evidence has implicated theimportance of PGs in several physiological processes affecting the gastroin-

关键词： PROSTAGLANdINS PHARMACOGY

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人工晒黑制品在青年人中的使用

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世界核心医学期刊文摘（皮肤病学分册） 2006年第8期2卷 53-54页

作者： Brooks K. Brooks d. dajani z. A.C. Geller 张路坤 department of dermatology Boston University School of MedicineBoston Massachusetts USA

Background: Neither the prevalence of sunless tanner use nor its impact on sunburning and tanning bed use has been evaluated in the United States. Objective: We surveyed young adults in greater Boston to measure use of artificial tanning products, as well as recent history of sunburns and tanning bed use. Methods: In July 2004, 448 individuals 18 to 30 years of age completed a brief questionnaire at universities, shopping venues, and parks. Results: Twenty-two percent of respondents used sunless tanning lotions in the preceding 12 months, and another 22% had not used them but would consider doing so in the coming year. Sunless tanning users were more likely to be female, younger, and more likely to report being severe burners. Both users and potential users were more likely to have sunburned during the summer and to have used tanning beds than those who neither used nor intended to use sunless tanning lotions, even after controlling for skin type. Limitations: The study was based on a non-randomly selected sample in one city and was cross-sectional in nature. Conclusion: Our study raises the possibility that sunless tanning products do not decrease rates of sunburning or use of tanning beds. While safe alternatives to ultraviolet exposure are desirable, the potential risks of widely endorsing artificial tanning products must be considered.

关键词：青年人制品人工治疗床问卷调查皮肤类型使用者日光鞣酸使用率

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