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RING OPENING POLYMERIZATION OF TETRAHYDROFURAN CATALYSED BY MAGHNITE-H^+

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Chinese Journal of Polymer Science 2012年第1期30卷 56-62页

作者： khadidja Benkenfoud Amine Harrane Mohammed Belbachir Laboratoire de Chimie des Polymeres Departement de Chimie Faculte des SciencesUniversite d'Oran Es-SeniaBP No 1524 El M'Naouar31000 OranAlgeria

The cationic ring-opening polymerization of tetrahydrofiiran using maghnite-H~＋ is ***-H~＋,is a non-toxic solid catalyst issued from proton exchanged montmorillonite ***,also called ＂poly（butandiol） ether＂,with acetate and hydroxyl end groups was successfully *** of reaction temperature, weight ratio of initiator/monomer and reaction time on the conversion of monomer and on the molecular weight are investigated.A cationic mechanism of the reaction was *** chemistry can be considered as a suitable route for preparing poly（THF） as a soft segment for thermoplastic elastomers.

关键词： Montmorillonite Maghnite Ring opening polymerization THF

The effects of step inclination and air injection on the water flow in a stepped spillway:A numerical study

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Journal of Hydrodynamics 2017年第2期29卷 322-331页

作者： khadidja Kherbache Xavier Chesneau Belkacem Zeghmati Stéphane Abide Saadia Benmamar Universite de Perpignan Via Domitia(UPVD) LAhoratoire the Mathematiques et de PhySique(LAMPS)EA4217F-66860PerpignanFrance Ecole Nationale Polytechnique Laboratoire de Recherche des Sciences de I'eau10 Avenue Hassen Badi16000 AlgerAlgerie

In this work, we perform a numerical study of a water flow over a stepped spillway. This flow is described by the Reynolds averaged Navier-Stokes equation （RANS） associated with the turbulence k - model. These equations are solved using a commercial software based on the finite volume scheme and an unstructured mesh. The air-water flow was modeled using volume of fluid （VOF） and multiphasic methods. The characteristics of the profile, etc.. We analyze the effects on the flow structure of the flow were investigated including the total pressure, the velocity steps and countermarch inclination, the air injection through the countermarch into the water flow and the dynamics water discharges. Results show that the inclination of the countermarch relative to the vertical and the air injection into the water flow increase the total pressure in the neighbourhood of the steps.

关键词： Stepped spillway turbulence air-water air injection volume of fluid (VOF) method multiphasic method

Numerical Simulation of Turbulent Diffusion Flames of a Biogas Enriched with Hydrogen

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Fluid Dynamics & Materials Processing 2024年第1期20卷 79-96页

作者： Naima Krarraz Amina Sabeur khadidja Safer Ahmed Ouadha Laboratoire des Science et Ingénierie Maritimes Facultéde Génie MécaniqueUniversitédes Sciences et de la Technologie d’Oran Mohamed BoudiafOranAlgérie Laboratoire des Carburants Gazeux et de l’Environnement Facultéde Génie MécaniqueUniversitédes Sciences et de la Laboratoire des Carburants Gazeux et de l’Environneme

Any biogas produced by the anaerobic fermentation of organic materials has the advantage of being an environmentally friendly ***,the relatively low calorific value of such gases makes their effective utilization in practical applications relatively *** present study considers the addition of hydrogen as a potential solution to mitigate this *** particular,the properties of turbulent diffusion jet flames and the related pollutant emissions are investigated numerically for different operating *** related numerical simulations are conducted by solving the RANS equations in the frame of the Reynolds Stress Model in combination with the flamelet *** effects are also taken into account and the combustion kinetics are described via the GRI-Mech 3.0 reaction *** considered hydrogen fuel enrichment spans the range from 0%to 50%in terms of *** varies between 1 and 10 *** results show that both hydrogen addition and pressure increase lead to an improvement in terms of mixing quality and have a significant effect on flame temperature and *** also reduce CO_(2) emissions but increase NOx *** NO is shown to be the predominant NO formation mechanism.

关键词： Biogas hydrogen diffusion flame turbulence NO formation route pressure

High prevalence of multidrug-resistance in Acinetobacter baumannii and dissemination of carbapenemase-encoding genes bla_(OXA-23-like),bla_(OXA-24-like)and bla_(NDM-1) in Algiers hospitals

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Asian Pacific Journal of Tropical Medicine 2015年第6期8卷 439-447页

作者： khadidja Khorsi Yamina Messai Moufida Hamidi Houria Ammari Rabah Bakour Laboratory of Cellular and Molecular Biology Faculty of Biological SciencesUniversity of Sciences and Technology Houari BoumedieneP.B.32 El-AliaBab-Ezzouar16111 AlgiersAlgeria Hospital Salim Zemirli Route de Baraki.BP N'71El Harrach 16000AlgiersAlgeria University Hospital Isaad Hassani.Rue Ibrahim Hadjeras Beni Messous 16206AlgiersAlgeria

Objective:To assess and characterize antibiotic resistance in Acinetobacter baumannii strains recovered from 5 health-care facilities in ***:Antibiotic susceptibility testing was performed by agar diffusion and agar dilution methods,resistance genes were identified by PCR and sequencing,and molecular typing of isolates was carried out by enterobacterial repetitive intergenic consensus-PCR(ERIC-PCR).Results:Among 125 tested isolates,117(93.6% ) were *** which 94(75.2% ) were imipenem *** bla_(ADC)and bla_(OXA-51-like) genes were detected in all isolates,in association with ISAba I sequence in 84% and 8% (imipenem resistant) of isolates,*** bla_(OXA-23-like) and bla_(OXA-24-like)carbapenemase genes were delected in 67.02% and 20.21% of imipenem-resistant isolates,*** bla_(OXA-23-like) gene is linked to ISAba1 or ISAba4 *** metallo-β-lactamase NDM-1 gene was found in 10(10.6% ) imipenem-resisianl strains from three hospitals,it is linked to ISAba125 clement in nine *** spectrum β-lactamases production was not *** and cefotaxime resistance phenolypes could not be transferred to Escherichia coli by *** membrane protein CarO gene was not delected in four imipenem-resisianl *** aac(6')-***1,sul2,tetA and tetB genes were present in 5.31% .36.17% .77.65% .1.06% and 65.92% of strains,*** 1 integrons were detected in 23.4% ***-PCR typing showed a genetic diversity among bla_(OXA-23-like) and bla_(OXA-24-like) positive strains,while clonality was observed among bla_(NDM-1)***:This study highlighted the high prevalence of imipenem resistance in Acinetobacter baumannii in Algiers hospitals mediated mainly by bla_(OXA-23-like),bla_(OXA-24-like),and bla_(NDM-1) genes.

关键词： Acinetobacter baumannii Multidrug-resistance Carbapenemase bla_(OXA-23-like) bla_(OXA 24 like) bla_(NDM-1) carO Hospital Algiers

BHJO: A Novel Hybrid Metaheuristic Algorithm Combining the Beluga Whale, Honey Badger, and Jellyfish Search Optimizers for Solving Engineering Design Problems

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Computer Modeling in Engineering & Sciences 2024年第10期141卷 219-265页

作者： Farouq Zitouni Saad Harous Abdulaziz S.Almazyad Ali Wagdy Mohamed Guojiang Xiong Fatima Zohra Khechiba khadidja Â Kherchouche Department of Computer Science and Information Technology Kasdi Merbah UniversityP.O.Box 30000OuarglaAlgeria Department of Computer Science College of Computing and InformaticsUniversity of SharjahP.O.Box 27272SharjahUnited Arab Emirates Department of Computer Engineering College of Computer and Information SciencesKing Saud UniversityP.O.Box 51178Riyadh11543Saudi Arabia Operations Research Department Faculty of Graduate Studies for Statistical ResearchCairo UniversityGiza12613Egypt Applied Science Research Center Applied Science Private UniversityAmman11937Jordan Guizhou Key Laboratory of Intelligent Technology in Power System College of Electrical EngineeringGuizhou UniversityGuiyang550025China

Hybridizing metaheuristic algorithms involves synergistically combining different optimization techniques to effectively address complex and challenging optimization *** approach aims to leverage the strengths of multiple algorithms,enhancing solution quality,convergence speed,and robustness,thereby offering a more versatile and efficient means of solving intricate real-world optimization *** this paper,we introduce a hybrid algorithm that amalgamates three distinct metaheuristics:the Beluga Whale Optimization(BWO),the Honey Badger Algorithm(HBA),and the Jellyfish Search(JS)*** proposed hybrid algorithm will be referred to as *** this fusion,the BHJO algorithm aims to leverage the strengths of each *** this hybridization,we thoroughly examined the exploration and exploitation capabilities of the BWO,HBA,and JS metaheuristics,as well as their ability to strike a balance between exploration and *** meticulous analysis allowed us to identify the pros and cons of each algorithm,enabling us to combine them in a novel hybrid approach that capitalizes on their respective strengths for enhanced optimization *** addition,the BHJO algorithm incorporates Opposition-Based Learning(OBL)to harness the advantages offered by this technique,leveraging its diverse exploration,accelerated convergence,and improved solution quality to enhance the overall performance and effectiveness of the hybrid ***,the performance of the BHJO algorithm was evaluated across a range of both unconstrained and constrained optimization problems,providing a comprehensive assessment of its efficacy and applicability in diverse problem ***,the BHJO algorithm was subjected to a comparative analysis with several renowned algorithms,where mean and standard deviation values were utilized as evaluation *** rigorous comparison aimed to assess the performance of the BHJOalgorithmabout its counterparts,shedd

关键词： Global optimization hybridization of metaheuristics beluga whale optimization honey badger algorithm jellyfish search optimizer chaotic maps opposition-based learning

A comparative study of a direct and pulse electrodeposition method of TiO_(2)films and its effect on photoelectrocatalytic degradation of methyl orange dye

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Optoelectronics Letters 2021年第6期17卷 334-341页

作者： khadidja Hadj Larbi Farid Habelhames Meriem Lakhdari Farid Bennabi Belkacem Nessark Mehdi Adjdir Abdelkader Echchergui Nebatti Bouhalouane Amrani Laboratoire d'électrochimie et matériaux(LEM) Facultéde TechnologieDépartement de génie des procédésUniversitéFerhat Abbas Sétif-1Sétif19000Algérie Laboratory of Applied Chemistry University ofAin-Temouchent Belhadj BouchaibAlgeria Laboratory of Applied Organic Synthesis Faculty of Exact and Applied SciencesUniversity Oran1 Ahmed Ben BellaBP 1524 El M'NaouerOran 31000Algeria Laboratory of Materials Sciences and Applications(LMSA) University of Ain-Temouchent Belhadj BouchaibAlgeria Electron Microscopy Center Faculty of Exact and Applied SciencesUniversity of Oran1 Ahmed Ben BellaOranAlgeria

The present study reports the titanium dioxide(TiO_(2))films synthesized from TiCl3 precursor on ITO glass substrates using two electrochemical techniques,namely direct electro-deposition(DE)and pulse electro-deposition(PE).The synthesis potential during the time-on(Ton)period was fixed at-1.5 ***,the open-circuit potential was applied during the time-off(Toff)*** effect of the technique of electro-deposition and Toff duration on the properties of TiO_(2)films and their photoelectron-catalytic activity were *** obtained films were investigated by X-ray diffraction(XRD),scanning electron microscopy(SEM),UV-VIS spectrometer,and photocurrent measurement *** is found that the use of the PE technique at different Toff improves the properties of TiO_(2)films compared to the DE *** XRD patterns show the anatase phase with a marked preferential orientation along the(101)direction for all *** the SEM analysis,it is seen a significant change from big multigrain agglomerates at DE to a dense film structure and small multigrain agglomerates at different *** the Toff decreases from 3 s to 1 s,the photocurrent response rises and reaches a high value of about 12 m A/cm^(2).Compared with DE,and under UV light the photocatalytic property of TiO_(2)film synthesis via PE has been improved in the degradation of methyl orange(MO).Finally,the films deposited at low Toff(Toff=1 s)show a faster degradation of MO.

关键词： films orange effect

比较内毒素预处理和缺血预处理对大鼠肝脏热缺血再灌注损伤保护效应的实验研究

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比较内毒素预处理和缺血预处理对大鼠肝脏热缺血再灌注损伤保护效...

作者： khadidja 中南大学

学位级别：硕士

目的:探讨内毒素预处理是否能够对肝脏缺血再灌注损伤起到保护效应,并与传统的抗缺血-再灌注损伤的方法——缺血预处理做比较,探讨二者在作用机制上是否存在共同点。方法:应用大鼠原位70%肝脏热缺血再灌注损伤模型,36只大鼠按处理方式... 详细信息

目的:探讨内毒素预处理是否能够对肝脏缺血再灌注损伤起到保护效应,并与传统的抗缺血-再灌注损伤的方法——缺血预处理做比较,探讨二者在作用机制上是否存在共同点。方法:应用大鼠原位70%肝脏热缺血再灌注损伤模型,36只大鼠按处理方式不同随机分为3组,每组12只:单纯缺血-再灌注损伤组(Group IR):无损伤血管夹夹闭大鼠门静脉左支及左肝动脉,造成大鼠70%肝脏缺血30分钟,然后开放灌注1h;缺血预处理组(Group IP):在大鼠肝脏缺血前预先予以5min-5min×2次的缺血预处理,随后的处理同IR组;内毒素预处理组(Group EP):在大鼠肝脏缺血前48h预先腹腔内注射1次LPS 0.25mg/kg,24h后重复腹腔内注射1次LPS 0.25mg/kg,随后的处理同IR组;另设假手术组(Group Sham)作为阴性对照,所有实验动物均于复灌后1h取材,检测外周血ALT、AST浓度及肝组织匀浆内TNF-α、MDA含量,另取肝脏左前叶组织甲醛固定,行病理组织学检查。结果:(1)IP组和EP组大鼠再灌注后1h时的外周血ALT、AST浓度均明显低于IR组(p＜0.05),病理组织学显示肝损害较IR组为轻。(2)IP组和EP组大鼠再灌注后1h时的肝组织匀浆内的TNF-α、MDA含量均明显低于IR组(p＜0.05)。(3)IP组和EP组各指标测量值之间的差异不显著(p＞0.05)。结论:(1)缺血预处理与内毒素预处理均能够对大鼠肝脏长时间热缺血后再灌注时的损伤起到良好的保护效应。(2)缺血预处理与内毒素预处理在保护大鼠肝脏热缺血-再灌注损伤的机制上可能存在共同点,体现在二者均能使肝组织内TNF-α、MDA含量下降。(3)缺血预处理与内毒素预处理保护大鼠肝脏热缺血-再灌注损伤的效果相当。

关键词：缺血预处理内毒素预处理缺血-再灌注损伤肝脏

累积叠轧焊Al/Mg/Al多层复合材料的腐蚀行为

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Transactions of Nonferrous Metals Society of China 2024年第1期34卷 122-138页

作者： Ismail BENCHERIFA khadidja ABIB Khereddine ABDEL YAZID Baya ALILI Djamal BRADAI Laboratory of Metallic and Semiconducting Materials(LMSM) Department of Mechanical EngineeringUniversity of BiskraB.P.14507000BiskraAlgeria Laboratory of Materials Physics Faculty of PhysicsUniversity of Sciences and Technology-Houari Boumediene(U.S.T.H.B.)P.O.Box 32El-AliaBab-EzzouarDZ-16111AlgiersAlgeria Center for Development of Advanced Technologies CDTACitédu 20 août 1956Baba-Hassen16303 AlgiersAlgeria

研究累积叠轧焊(ARB)Al1050/AZ31/Al1050多层复合材料的腐蚀行为,腐蚀介质为3.5%Na Cl(质量分数)溶液,分析测试手段包括动电位极化测试(PDP)、电化学阻抗谱(EIS)、扫描电子显微镜(SEM-EDS)、拉曼光谱和X射线衍射(XRD)等。为了深入研究Al... 详细信息

研究累积叠轧焊(ARB)Al1050/AZ31/Al1050多层复合材料的腐蚀行为,腐蚀介质为3.5%Na Cl(质量分数)溶液,分析测试手段包括动电位极化测试(PDP)、电化学阻抗谱(EIS)、扫描电子显微镜(SEM-EDS)、拉曼光谱和X射线衍射(XRD)等。为了深入研究Al1050/AZ31/Al1050多层复合材料的耐腐蚀性和腐蚀产物,对ARB制备的Al1050/Al1050/Al1050多层复合材料进行了相似的测试作为对比。动电位极化曲线和电化学阻抗谱显示,ARB应变水平会显著影响腐蚀速率。与Al1050/Al1050/Al1050样品相比,Al1050/AZ31/Al1050多层复合材料具有更高的腐蚀速率和更低的极化电阻。AZ31层对腐蚀过程起主导作用。拉曼和XRD分析结果表明主要腐蚀产物为Mg(OH)2,且不含任何氯化合物(如(Mg(OH)_(2))·MgCl_(2))。

关键词：累积叠轧焊 Al1050/AZ31/Al1050 多层复合材料腐蚀金属间化合物

人重组VEGF蛋白、多克隆抗体的制备及在肿瘤检测方面的初步研究

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人重组VEGF蛋白、多克隆抗体的制备及在肿瘤检测方面的初步研究

作者： khadidja CHENTOUF 东北师范大学

学位级别：硕士

血管内皮生长因子(VEGF)是一种分子量为34-42 kDa的、由两个相同多肽链通过二硫键构成的同源二聚体糖蛋白,是一种重要的促血管生成因子。VEGF在许多种类的细胞中都有表达,在肿瘤细胞的表达尤为显著。VEGF作为一种特异的有丝分裂原,可以... 详细信息

血管内皮生长因子(VEGF)是一种分子量为34-42 kDa的、由两个相同多肽链通过二硫键构成的同源二聚体糖蛋白,是一种重要的促血管生成因子。VEGF在许多种类的细胞中都有表达,在肿瘤细胞的表达尤为显著。VEGF作为一种特异的有丝分裂原,可以促进内皮细胞的迁移和增殖,诱导肿瘤的新生血管生成,在肿瘤的生长、转移过程中发挥了重要作用。提示基于VEGF肿瘤辅助诊断试剂的研制具有可行性。本研究构建了带有6个His标签的VEGF原核表达质粒,将重组质粒转入大肠杆菌中,VEGF蛋白以包涵体的形式表达。使用Ni离子亲和层析方法对蛋白进行了纯化,并利用纯化后的蛋白免疫家兔,获得了抗血清,抗体效价达到1:25600。使用Protein G亲和纯化方法纯化了抗血清,利用纯化后的VEGF多克隆抗体和单克隆抗体,初步建立了检测血清VEGF的夹心ELISA方法。并用该方法对25名健康人和33名肿瘤患者的血清VEGF含量进行了检测。结果发现,肿瘤患者血清中的VEGF含量(平均为407pg/ml)高于健康人(未检测到),二者差异显著(P<0.05)。本研究利用基因工程手段,制备了人重组VEGF165蛋白和多克隆抗体,初步建立了基于双抗体夹心ELISA的VEGF血清学检测方法并应用于临床血清检测,为开发基于VEGF肿瘤辅助诊断试剂奠定了基础。

关键词： VEGF 原核表达多克隆抗体 ELISA 肿瘤检测