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Chinese Chemical Letters 2017年第2期28卷 312-318页

作者： Savan M.darjee keyur d.bhatt Urvi S.Panchal Vinod K.Jain department of Chemistry School of Sciences Gujarat University Ahmedabad 380009 India department of Chemistry C.U. Shah University Wadhwan 363030 India

Water dispersible silver nanoparticles（AgNps） were prepared using thiacalix[4]arene tetrahydrazide（TCTH） as a reducing and stabilizing ***-AgNps were characterized by surface plasmon resonance（SPR）,transmission electron microscopy（TEM） and energy dispersive X-ray（EdX）.Relatively uniform 20 nm spherical particles of TCTH-AgNps were efficiently formed over a pH range of 5-9 and from 10-40 ℃.The interaction behavior of TCTH-AgNps with different amino acids was investigated using spectrophotometry and *** the amino acids tested,only tryptophan and histidine showed fluorescence quenching and fluorescence enhancement,*** linear detection range by Stern-Volmer plot was 5 nmol/L to 0.48 μmol/L for tryptophan and 4 nmol/L to 0.54 μmol/L for ***-AgNps were able to effectively reduce the levels of gram-positive bacteria,gram-negative bacteria,and *** properties argue for the potential use of TCTH-AgNps as detectors of histidine and tryptophan and as antibiotics.

关键词： Silver nanoparticles Fluorescent sensor Colorimetric sensor Thiacalixarene

Efficacy of a diabetes Specific Nutritional Supplement (dSNS) on Glycemic Response in Prediabetic Adults: A Two-Armed, Open-Labelled Randomized Controlled Study

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Food and Nutrition Sciences 2024年第7期15卷 612-643页

作者： deepti Khanna Kejal Joshi Reddy Hema S. Gopalan Jaladhi bhatt Jayanti Gupta Simran Sethi Parth Joshi Manoj Pareek department of R&d Hindustan Unilever Limited Gurugram India Mumbai India Cliantha Research Ahmedabad India

It is well known that diabetes Specific Nutritional Supplements (dSNSs) are linked to improved glycemic control in individuals with diabetes. However, data on efficacy of dSNSs in prediabetics is limited. This was a two-armed, open-labelled, randomized controlled six-week study on 199 prediabetics [30 - 65 years;Glycosylated Hemoglobin (HbA1c) 5.7% - 6.4% and/or Fasting Blood Glucose (FBG) 100-125 mg/dl]. Two parallel phases were conducted: Acute Blood Glucose Response (ABGR) and Intervention phase. Prediabetic participants were randomized into test (n = 100) and control (n = 99). The primary objective was to assess the ABGR of dSNS versus an isocaloric snack, measured by incremental Area under the Curve (iAUC). Test and control received 60 g of dSNS and 56 g of isocaloric snack (cornflakes) respectively, both in 250 ml double-toned milk on visit days 1, 15, 29 and 43. Postprandial Blood Glucose (PPG) was estimated at 30, 60, 90, 120, 150 and 180 minutes. during the 4 weeks intervention phase, the test group received dSNS with lifestyle counselling (dSNS + LC) and was compared with the control receiving lifestyle counselling alone (LC alone). Impact was studied on FBG, HbA1C, anthropometry, body composition, blood pressure, nutrient intake, and physical activity. The impact of dSNS was also studied using CGM between two 14-day phases: CGM1 baseline (days 1 - 14) and CGM2 endline (days 28 - 42). dSNS showed significantly lower PPG versus isocaloric snack at 30 (p 12, and chromium were reported by dSNS + LC versus LC alone. No other significant changes were reported between groups. It may be concluded that dSNS may be considered as a snack for prediabetic or hyperglycemic individuals requiring nutritional support for improved glycemic control.

关键词： diabetes Specific Nutritional Supplement Prediabetes Acute Blood Glucose Response Incremental Area under Curve Lifestyle Counselling

Trends in prevalence and mortality of gastroschisis and omphalocele in the United States from 2010 to 2018

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World Journal of Pediatrics 2022年第7期18卷 511-514页

作者： Parth bhatt Frank Adusei Poku Jacob Umscheid Marian Ayensu Narendrasinh Parmar Rhythm Vasudeva keyur donda Harshit doshi Fredrick dapaah-Siakwan United Hospital Center BridgeportWVUSA University of Central Oklahoma EdmondOKUSA University of Kansas School of Medicine WichitaKSUSA Woodhull Medical Center New YorkUSA Brookdale University Hospital and Medical Center BrooklynNYUSA University of South Florida TampaFLUSA Golisano Children's Hospital of Southwest Florida FortMyersFLUSA Neonatal Intensive Care Unit Valley Children's Hospital9300 Valley Children's PlaceSE 20MaderaCA 93636USA

Gastroschisis and omphalocele are the two most common congenital defects of the anterior abdominal *** etiologies remain unclear,but while gastroschisis is associ-ated with young maternal age,maternal smoking,maternal alcohol and illicit drug use during pregnancy omphalocele is frequently associated with genetic disorders and other congenital anomalies[1].The incidence of gastroschisis in the United States(US)has increased with an estimated inci-dence of 4.6 per 10,000 live births(LB)between 2010 and 2014[2].A recent study capturing information on 20%of infants admitted to neonatal intensive care unit(NICU)in the US showed a decrease in gastroschisis hospitalizations while that of omphalocele remained stable[3].However,it lacks generalizability[3].Our aim was to provide updated trends of gastroschisis and omphalocele hospitalizations in the US between 2010 and 2018 using population-based and nationally representative databases.

关键词： admitted halo maternal

Characterization of Agro-diversity by Seed Storage Protein Electrophoresis:Focus on Rice Germplasm from Uttarakhand Himalaya,India

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Rice science 2010年第2期17卷 122-128页

作者： Arun JUGRAN Indra d.bhatt Ranbeer S.RAWAL G.B.Pant Institute of Himalayan Environment and development Kosi-Katarmal

The characteristics of 48 rice varieties from Uttarakhand Himalaya, India were detected by morphological and biochemical markers. The grains of the selected rice varieties varied in their morphological （grain length, grain width and grain weight） and biochemical characters （sodium dodecyl sulfate polyacrylamide gel electrophoresis, SdS-PAGE）. Based on the presence of 70, 65, 60, 57, 37-39, 22-23, 13 and 10 kda protein bands in the 48 rice varieties, seven types of profiles were identified. An unweighted pair group average method with arithmetic mean （UPGMA） dendrogram based on cluster analysis of genetic similarity of the protein bands showed two distinct groups with 1%-78% similarity coefficients. The presence of characteristic bands in selected varieties is a useful parameter for identification of rice germplasm.

关键词： rice seed storage protein sodium dodecyl sulfate polyacrylamide gel electrophoresis genetic diversity polymorphism varietal identification

Turn-on fluorescence probe for selective detection of Hg(Ⅱ)by calixpyrrole hydrazide reduced silver nanoparticle: Application to real water sample

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Chinese Chemical Letters 2016年第5期27卷 731-737页

作者： keyur d. bhatt disha J. Vyas Bharat A. Makwana Savan M. darjee Vinod K. Jain Hemangini Shah department of Chemistry C.U. Shah University Wadhwan 363030 India department of Chemistry School of Sciences Gujarat University Ahmedabad 380009 India

A simple and quick method for the synthesis of water dispersible stable silver nanoparticles has been developed. Calix[4]pyrrole octahydrazide （CPOH）, has been successfully used as a reducing as well as stabilizing agent for the synthesis of silver nanoparticles. CPOH-AgNps have been duly characterized by SPR, PSA, TEM and EdX-ray. The ability of CPOH-AgNps as selective and sensitive sensor for various ions （Pb（Ⅱ）, Cd（II）, Mn（Ⅱ）, Fe（Ⅲ）, Ni（Ⅱ）, Zn（Ⅱ）, Hg（Ⅱ）, Co（Ⅱ）, Cu（Ⅱ）） by colorimetry and spectrofluorimetry has been explored. CPOH-AgNps were found to be selective only for Hg（Ⅱ） ions. Nanomolar concentration of Hg（Ⅱ） ions can also be determined by spectrofluorimetry by increase in fluorescence intensity. Linear range of detection of Hg（Ⅱ） ions in water was found to be from 1nmol/L to mol/L. The method has been successfully applied for determination of Hg（Ⅱ） ions in ground water and industrial effluent waste water samples.

关键词： Calixpyrrole Silver nanoparticles Fluorescence study Colorimetric sensor Water samplesHg(Ⅱ) ions

Therapeutic potential of snake venom in cancer therapy:current perspectives

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Asian Pacific Journal of Tropical Biomedicine 2013年第2期3卷 156-162页

作者： Vivek Kumar Vyas keyur Brahmbhatt Hardik bhatt Utsav Parmar Institute of Pharmacy Nirma UniversityAhmadabad 382481GujaratIndia Arihant School of Pharmacy and Bio Research Institute

Many active secretions produced by animals have been employed in the development of new drugs to treat diseases such as hypertension and *** venom toxins coutributed significantly to the treatment of many medical *** are many published studies describing and elucidating the anti-cancer potential of snake *** therapy is one of the main areas for the use of protein peptides and enzymes originating from animals of different *** of these proteins or peptides and enzymes from snake venom when isolated and evaluated may bind specifically to cancer cell membranes,affecting the migration and proliferation of these *** of substances found in the snake venom present a great potential as anti-tumor *** this review,we presented the main results of recent years of research involving the active compounds of snake venom that have anticancer activity.

关键词： Snake venom Cytotoxin Anticancer agents Apoptosis inducer

Structural and mass transport properties of liquid ytterbium in the temperature range 1123 K–1473 K

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Chinese Physics B 2023年第6期32卷 481-488页

作者： d d Satikunvar N K bhatt B Y Thakore department of Physics Sardar Patel UniversityVallabh VidyanagarGujarat 388120India department of Physics Maharaja Krishnakumarsinhji Bhavnagar UniversityBhavnagarGujarat 364001India

We have studied the structural and atomic transport properties of liquid f-shell Yb in the temperature range 1123 K–1473 K. Pair interactions between atoms are derived using a local pseudopotential. The potential parameters are fitted to the phonon dispersion curve at room temperature. The local pseudopotential used in the present study is computationally more efficient with only three parameters, and it is found to be transferable to the liquid phase without changing the *** the various computed properties agree with reported theoretical and experimental findings, the adopted fitting scheme is justified. As a significant outcome of the study, we find that(i) the melting in Yb is governed by the Lindemann's law,(ii)the mass transport mechanism obeys the Arrhenius law,(iii) the role of the three-particle correlation function in deriving the velocity autocorrelation function is small,(iv) the mean-square atomic displacement is more sensitive to the choice of interaction potential than the other bulk properties, and(v) liquid Yb does not show liquid–liquid phase transition within the studied temperature range. Further, due to the good description of the structural and mass transport properties, we propose that Yb remains divalent at reduced density.

关键词： transport properties pseudopotential single-particle dynamics ytterbium

Computer Modelling of Compact 28/38 GHz dual-Band Antenna for Millimeter-Wave 5G Applications

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Computer Modeling in Engineering & Sciences 2023年第12期137卷 2867-2879页

作者： Amit V.Patel Arpan desai Issa Elfergani Hiren Mewada Chemseddine Zebiri keyur Mahant Jonathan Rodriguez Raed Abd-Alhameed department of Electronics and Communication Engineering Chandubhai S Patel Institute of Technology(CSPIT)Charotar University of Science and Technology(CHARUSAT)Changa388421India The Instituto de Telecomunica珲es Campus Universitário de SantiagoAveiro3810-193Portugal School of Engineering and Informatics University of BradfordBradfordBD71DPUK Electrical Engineering department Prince Mohammad Bin Fahd UniversityAl Khobar31952Saudi Arabia department of Electronics Laboratoire d’Electronique de Puissance et Commande Industrielle(LEPCI)University of Ferhat AbbasSétif19000Algeria

A four-element compact dual-band patch antenna having a common ground plane operating at 28/38 GHz is proposed formillimeter-wave communication systems in this ***-input-multiple-output(MIMO)antenna geometry consists of a slotted ellipse enclosed within a hollow circle which is orthogonally rotated with a connected partial ground at the *** overall size of the four elements MIMO antenna is 2.24λ×2.24λ(at 27.12GHz).The prototype of four-element MIMOresonator is designed and printed using Rogers RTduroid 5880 withε_(r)=2.2 and loss tangent=0.0009 and having a thickness of 0.8 *** covers dual-band having a fractional bandwidth of 15.7%(27.12-31.34 GHz)and 4.2%(37.21-38.81 GHz)for millimeter-wave applications with a gain of more than 4 dBi at both *** proposed antenna analysis in terms ofMIMOdiversity parameters(Envelope Correlation Coefficient(ECC)and diversity Gain(dG))is also carried *** experimental result in terms of reflection coefficient,radiation pattern,gain and MIMOdiversity parameter correlates very well with the simulated ones that show the potential of the proposed design for MIMO applications at millimeter-wave frequencies.

关键词： Connected ground diversity parameters dual-band antenna fifth generation(5G) mmwave multiple input multiple output(MIMO)

Variations in seed germination ofHippophae salicifolia with different presoaking treatments

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Journal of Forestry Research 2009年第1期20卷 27-30页

作者： S. Airi, I.d. bhatt A. bhatt, R.S. Rawal, U. dhar G.B. Pant Institute of Himalayan Environment and development Kosi- Katarmal Almora - 263 643 （UK） India

H 的成熟种子。 salicifolia ，从五起源镇定(即 Hanuman Chatti ， Helang ， Lata ， Rambara 和 Janggal Chatti )在西方 Himalaya ，印度，与层化被对待(在为 15 ， 30 和 60 天的 4 °C )并且在 GA 3的不同集中( 5 ， 10 ， 20... 详细信息

H 的成熟种子。 salicifolia ，从五起源镇定(即 Hanuman Chatti ， Helang ， Lata ， Rambara 和 Janggal Chatti )在西方 Himalaya ，印度，与层化被对待(在为 15 ， 30 和 60 天的 4 °C )并且在 GA 3的不同集中( 5 ， 10 ， 20 公里)， KNO 3( 50 ， 100 ， 200 公里)并且硫脲( 50 ， 100 ， 200 公里)在种子萌芽决定变化的答案。结果表明从在不同预先播种的处理下面的不同起源的种子的萌芽率显著地在控制与那些相比被增加(24%30%) 。与硫脲(100 公里) 对待的种子有最高的萌芽率(76%83% 为不同种子采购原料) ，由那些列在后面(63%71% 为不同种子采购原料) 有层化的 pretreated (4 ° C， 30 天) 。GA3 处理显著地弄短吝啬的萌芽时间(MGT ) 并且改善种子发芽率。考虑实际适用性和费用有效性，硫脲(100 公里) 和层化(在 4 ° C ) 为种子萌芽的处理通过 H 的种子为集体增加被推荐。在西方 Himalaya 的村庄 / 森林托儿所的 salicifolia，印度。

关键词：种子发芽预浸处理层次硫脲

Antioxidative,antimicrobial and anti-inflammatory activities and release of ultra-filtered antioxidative and antimicrobial peptides during fermentation of sheep milk:In-vitro,in-silico and molecular interaction studies

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Food Bioscience 2022年第3期47卷 583-594页

作者： Jodhani keyur Ashokbhai Bethsheba Basaiawmoit Sujit das Amar Sakure Ruchika Maurya Mahendra Bishnoi Kanthi Kiran Kondepudi Srichandan Padhi Amit Kumar Rai Zhenbin Liu Subrota Hatia deptt.of dairy Microbiology Anand Agricultural UniversityAnand388110GujaratIndia deptt.of Rural development and Agricultural Production North-Eastern Hill UniversityTura CampusTura794002MeghalayaIndia deptt.of Agriculture Biotechnology Anand Agricultural UniversityAnand388110GujaratIndia Regional Center for Biotechnology FaridabadHaryana121001India Healthy Gut Research Group Food & Nutritional Biotechnology DivisionNational Agri-Food Biotechnology InstituteKnowledge CitySector 81SAS NagarPunjab140306India Institute of Bioresources and Sustainable development Regional CentreTadong737102SikkimIndia School of Food and Biological Engineering Shaanxi University of Science and Technology18Xi'an710021China

The antioxidative,antimicrobial,and anti-inflammatory properties of fermented sheep milk with *** (KGL4),as well as the generation of antioxidative and antimicrobial peptides,are evaluated in the *** and antibacterial activities in sheep milk fermented with KGL4 increased with incubation hours,along with varied antioxidative properties (ABTS assay:35.12%,hydroxyl free radical scavenging assay:29.12%,superoxide free radical scavenging activity:36.38%).Antimicrobial activity of fermented sheep milk against *** (19 mm),*** (15.67 mm),*** (14 mm),and *** (13 mm) was also ***,after 48 h,the KGL4 showed maximum proteolysis (10.40 mg/ml) at 2.5% rate of addition sheep *** antioxidative and antimicrobial activities of fermented sheep milk fractions (3 kda and 10 kda permeates and retentates) were also *** highest ABTS activity (26.90%) was found in 10 kda permeate,whereas the 3 kda retentate had higher hydroxyl free radical scavenging activity (69.20%) and 3 kda permeate showed maximum superoxide free radical scavenging activity (32.85%).The 10 kda retentate had shown maximum antimicrobial activity against *** (13.67 mm) and *** (17.00 mm).Proteins spotted on 2d gel electrophoresis of KGL4 were varied from 10 to 70 ***-LC/MS was used to identify 5 novel peptide sequences from 2-d gel *** in the BIOPEP database confirmed the antioxidative and antimicrobial effects of the novel fermented sheep milk *** sheep milk with KGL4 (SMKGL4) significantly reduced excessive TNF-α,IL-6,& IL-1β production in LPS-activated RAW 264.7 cells.

关键词： Fermentation Sheep milk Lactobacillus fermentum Antioxidative Antimicrobial Anti-inflammatory Peptides