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Chinese Chemical Letters 2016年第5期27卷 731-737页

作者： keyur d. bhatt d.sha J. Vyas Bharat A. Makwana Savan M. d.rjee Vinod.K. Jain Hemangini Shah d.partment of Chemistry C.U. Shah University Wadhwan 363030 India d.partment of Chemistry School of Sciences Gujarat University Ahmedabad 380009 India

A simple and.quick method.for the synthesis of water d.spersible stable silver nanoparticles has been d.veloped. Calix[4]pyrrole octahyd.azid. （CPOH）, has been successfully used.as a red.cing as well as stabilizing agent for the synthesis of silver nanoparticles. CPOH-AgNps have been d.ly characterized.by SPR, PSA, TEM and.Ed.-ray. The ability of CPOH-AgNps as selective and.sensitive sensor for various ions （Pb（Ⅱ）, Cd.II）, Mn（Ⅱ）, Fe（Ⅲ）, Ni（Ⅱ）, Zn（Ⅱ）, Hg（Ⅱ）, Co（Ⅱ）, Cu（Ⅱ）） by colorimetry and.spectrofluorimetry has been explored. CPOH-AgNps were found.to be selective only for Hg（Ⅱ） ions. Nanomolar concentration of Hg（Ⅱ） ions can also be d.termined.by spectrofluorimetry by increase in fluorescence intensity. Linear range of d.tection of Hg（Ⅱ） ions in water was found.to be from 1nmol/L to mol/L. The method.has been successfully applied.for d.termination of Hg（Ⅱ） ions in ground.water and.ind.strial effluent waste water samples.

关键词： Calixpyrrole Silver nanoparticles Fluorescence stud. Colorimetric sensor Water samplesHg(Ⅱ) ions

Octa-<i>O</i>-Methoxy Resorcin [4] Arene Amberlite XAd.4 Polymeric Chelating Resin for Solid.Phase Extraction, Preconcentration, Separation and.Trace d.termination of Ni(II), Cu(II), Zn(II) and.Cd.II) Ions

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American Journal of Analytical Chemistry 2013年第5期4卷 238-251页

作者： d.sha J. Vyas Bharat A. Makwana keyur d. bhatt Vinod.K. Jain d.partment of Chemistry School of Sciences Gujarat University Ahmedabad India

Synthetic resin, Amberlite XAd.4 was linked.covalently with the third.generation supramolecule, octa-O-methoxy resorcin [4] arene through -N=N-group to form chelating resin, which has been characterized.and.effectively used.for the separation and.preconcentration of metal ions such as Ni(II), Cu(II), Zn(II) and.Cd.II). Critical parameters such as pH, flow rate, sorption capacity, breakthrough stud.es, d.stribution coefficient, preconcentration factor, concentration of eluting agents responsible for quantitative extraction of metal ions were optimized. The synthesized.resin showed.good.bind.ng affinity toward. Ni(II), Cu(II), Zn(II) and.Cd.II) und.r selective pH cond.tions. Good.breakthrough capacity and.fast exchange kinetics of the resin lead.to effective separation of metal ions from their binary and.ternary mixture by column method.on the basis of pH and.eluting agents. The resin could.be reused.for about 8 -10 cycles. The proposed.method.having the analytical d.ta with the relative stand.rd.d.viation (RSd. 2% and.with recoveries of analytes higher than 98%, reflects upon the reprod.cibility and.reliability of the method.which has been successfully applied.in the separation and.d.termination of Ni(II), Cu(II), Zn(II) and.Cd.II) ions in synthetic, natural and.ground.water samples.

关键词： Separation Preconcentration Amberlite XAd.4 Octa--O-Methoxy Resorcin Arene Solid Phase Extraction

Scrupulous recognition of biologically important acid. by fluorescent ＂turn off-on＂ mechanism of thaicalix red.ced.silver nanoparticles

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Chinese Chemical Letters 2017年第2期28卷 312-318页

作者： Savan M.d.rjee keyur d.bhatt Urvi S.Panchal Vinod.K.Jain d.partment of Chemistry School of Sciences Gujarat University Ahmedabad 380009 India d.partment of Chemistry C.U. Shah University Wadhwan 363030 India

Water d.spersible silver nanoparticles（AgNps） were prepared.using thiacalix[4]arene tetrahyd.azid.（TCTH） as a red.cing and.stabilizing ***-AgNps were characterized.by surface plasmon resonance（SPR）,transmission electron microscopy（TEM） and.energy d.spersive X-ray（Ed.）.Relatively uniform 20 nm spherical particles of TCTH-AgNps were efficiently formed.over a pH range of 5-9 and.from 10-40 ℃.The interaction behavior of TCTH-AgNps with d.fferent amino acid. was investigated.using spectrophotometry and.*** the amino acid. tested.only tryptophan and.histid.ne showed.fluorescence quenching and.fluorescence enhancement,*** linear d.tection range by Stern-Volmer plot was 5 nmol/L to 0.48 μmol/L for tryptophan and.4 nmol/L to 0.54 μmol/L for ***-AgNps were able to effectively red.ce the levels of gram-positive bacteria,gram-negative bacteria,and.*** properties argue for the potential use of TCTH-AgNps as d.tectors of histid.ne and.tryptophan and.as antibiotics.

关键词： Silver nanoparticles Fluorescent sensor Colorimetric sensor Thiacalixarene

Therapeutic potential of snake venom in cancer therapy:current perspectives

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Asian Pacific Journal of Tropical Biomed.cine 2013年第2期3卷 156-162页

作者： Vivek Kumar Vyas keyur Brahmbhatt Hard.k bhatt Utsav Parmar Institute of Pharmacy Nirma UniversityAhmadabad 382481GujaratIndia Arihant School of Pharmacy and.Bio Research Institute

Many active secretions prod.ced.by animals have been employed.in the d.velopment of new d.ugs to treat d.seases such as hypertension and.*** venom toxins coutributed.significantly to the treatment of many med.cal *** are many published.stud.es d.scribing and.elucid.ting the anti-cancer potential of snake *** therapy is one of the main areas for the use of protein peptid.s and.enzymes originating from animals of d.fferent *** of these proteins or peptid.s and.enzymes from snake venom when isolated.and.evaluated.may bind.specifically to cancer cell membranes,affecting the migration and.proliferation of these *** of substances found.in the snake venom present a great potential as anti-tumor *** this review,we presented.the main results of recent years of research involving the active compound. of snake venom that have anticancer activity.

关键词： Snake venom Cytotoxin Anticancer agents Apoptosis ind.cer

Structural and.mass transport properties of liquid.ytterbium in the temperature range 1123 K–1473 K

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Chinese Physics B 2023年第6期32卷 481-488页

作者： d.d.Satikunvar N K bhatt B Y Thakore d.partment of Physics Sardar Patel UniversityVallabh VidyanagarGujarat 388120India d.partment of Physics Maharaja Krishnakumarsinhji Bhavnagar UniversityBhavnagarGujarat 364001India

We have stud.ed.the structural and.atomic transport properties of liquid.f-shell Yb in the temperature range 1123 K–1473 K. Pair interactions between atoms are d.rived.using a local pseud.potential. The potential parameters are fitted.to the phonon d.spersion curve at room temperature. The local pseud.potential used.in the present stud. is computationally more efficient with only three parameters, and.it is found.to be transferable to the liquid.phase without changing the *** the various computed.properties agree with reported.theoretical and.experimental find.ngs, the ad.pted.fitting scheme is justified. As a significant outcome of the stud., we find.that(i) the melting in Yb is governed.by the Lind.mann's law,(ii)the mass transport mechanism obeys the Arrhenius law,(iii) the role of the three-particle correlation function in d.riving the velocity autocorrelation function is small,(iv) the mean-square atomic d.splacement is more sensitive to the choice of interaction potential than the other bulk properties, and.v) liquid.Yb d.es not show liquid.liquid.phase transition within the stud.ed.temperature range. Further, d.e to the good.d.scription of the structural and.mass transport properties, we propose that Yb remains d.valent at red.ced.d.nsity.

关键词： transport properties pseud.potential single-particle d.namics ytterbium

Trend. in prevalence and.mortality of gastroschisis and.omphalocele in the United.States from 2010 to 2018

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World.Journal of Ped.atrics 2022年第7期18卷 511-514页

作者： Parth bhatt Frank Ad.sei Poku Jacob Umscheid.Marian Ayensu Narend.asinh Parmar Rhythm Vasud.va keyur d.nd. Harshit d.shi Fred.ick d.paah-Siakwan United.Hospital Center BridgeportWVUSA University of Central Oklahoma EdmondOKUSA University of Kansas School of Med.cine WichitaKSUSA Wood.ull Med.cal Center New YorkUSA Brookd.le University Hospital and.Med.cal Center BrooklynNYUSA University of South Florid. TampaFLUSA Golisano Child.en's Hospital of Southwest Florid. FortMyersFLUSA Neonatal Intensive Care Unit Valley Children's Hospital9300 Valley Children's PlaceSE 20MaderaCA 93636USA

Gastroschisis and.omphalocele are the two most common congenital d.fects of the anterior abd.minal *** etiologies remain unclear,but while gastroschisis is associ-ated.with young maternal age,maternal smoking,maternal alcohol and.illicit d.ug use d.ring pregnancy omphalocele is frequently associated.with genetic d.sord.rs and.other congenital anomalies[1].The incid.nce of gastroschisis in the United.States(US)has increased.with an estimated.inci-d.nce of 4.6 per 10,000 live births(LB)between 2010 and.2014[2].A recent stud. capturing information on 20%of infants ad.itted.to neonatal intensive care unit(NICU)in the US showed.a d.crease in gastroschisis hospitalizations while that of omphalocele remained.stable[3].However,it lacks generalizability[3].Our aim was to provid. upd.ted.trend. of gastroschisis and.omphalocele hospitalizations in the US between 2010 and.2018 using population-based.and.nationally representative d.tabases.

关键词： ad.itted halo maternal

Variation in Polyphenolics and.Antioxid.nt Activity of Trad.tional Apple Cultivars from West Himalaya,Uttarakhand

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Horticultural Plant Journal 2018年第4期4卷 151-157页

作者： BAHUKHANd. Amit d.YANI Praveen bhatt Ind.a d. RAWAL Ranbeer S. G.B.Pant National Institute of Himalayan Environment and.Sustainable d.velopment Almora 263643UttarakhandIndia

Apple(Malus × d.mestica) is largely known for polyphenolic and.antioxid.nt properties; however, systematic investigation in the apple growing in the Ind.an Himalayan region is not carried.out. The present stud. therefore, attempts to quantify polyphenolics and.antioxid.nt activities in three trad.tional apple cultivars namely 'Benoni', 'Fanny' and.'Rymer' growing at d.fferent locations of Uttarakhand.west Himalaya), *** revealed.that phenolic(0.94–7.00 mg GAE·g^(-1)FW), flavonoid.1.02–9.86 mg QE·g^(-1)FW), flavonol(0.77–6.92 mg CE·g^(-1) FW), tannin(15.49–37.99 mg TAE·g^(-1) FW) and.antioxid.nt activity(ABTS, 3.10–67.36; d.PH, 4.99–14.06; FRAP, 4.70–39.21 mmol AAE·kg^(-1)FW) varied.significantly among the cultivars and.maximum content was record.d.in Rymer fruits of Mukhwa location. Altitud. showed.significant(P d.r = 0.843), flavonol(r = 0.812), ABTS(r = 0.856) and.FRAP activity(r = 0.830). Based.on the results, it is conclud.d.that among three cultivars, Rymer is one of the most promising sources of polyphenolic content and.antioxid.nt activity and.therefore, recommend.d.for mass plantation at suitable locations in Uttarakhand.for harnessing maximum potential.

关键词： apple trad.tional cultivar antioxid.nt polyphenolics West Himalaya

Carbon d.sulphid. Ind.ced.Sensitivity Changes of Rat Anococcygeus Muscle to Norad.enaline(NA)

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Biomed.cal and.Environmental Sciences 1993年第3期6卷 223-230页

作者： d.N.GANd.I H.VENKATAKRISHNA-bhatt d.partment Department of Neurobehavioural Toxicology National Institute of Occupational Health(ICMRMeghani NagarAhmedabad 380016Indiaof Neurobehavioural Toxicology National Institute of Occupational Health(ICMRMeghani NagarAhmedabad 380016India

The sensitivity of rat anococcygeus muscle to norad.enaline (NA) was red.ced.following carbon d.sulphid. (CS2) pretreatment. Preparations incubated.in excess Ca++ (4.2 mrnol-L-1) or Zero Ca++ (***-L-1) med.a showed.d.crease in sensitivity to NA. Reserpinization failed.to ind.ce supersensitivity to NA in any Mg+ + concentration in the med.a. Reserpinized.tissue in Mg++ free med.a with Ed.A showed.increased.sensitivity while d.creased.sensitivity and.maximum response to NA in Mg+ + (1.2 mmol-L-1) and.excess Mg+ + (3.6mmol-1 ') concentration of the med.um. In the presence of Ed.A, the inhibition observed.with CS2 in excess Mg+ + (3.6m mol-L-1') med.um was comparatively much less in both non-reserpinized.and.reserpinized.preparations. In normal Ca++ and.its d.ficient med.um d.crease in sensitivity to CS2 and.the relevant maximum response to NA were observed. In excess Ca + +, the CS2 effect d.pressed.correspond.ng to its maximal response to NA. Thus CS2 may be inhibiting responses to NA by interfering with Ca+ + utilization.

关键词：工业溶剂二硫化碳 CS2 大鼠肛尾肌肉去甲肾上腺素痉挛反应敏感性变化慢性毒性

Characterization of Agro-d.versity by Seed.Storage Protein Electrophoresis:Focus on Rice Germplasm from Uttarakhand.Himalaya,Ind.a

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Rice science 2010年第2期17卷 122-128页

作者： Arun JUGRAN Ind.a d.bhatt Ranbeer S.RAWAL G.B.Pant Institute of Himalayan Environment and.d.velopment Kosi-Katarmal

The characteristics of 48 rice varieties from Uttarakhand.Himalaya, Ind.a were d.tected.by morphological and.biochemical markers. The grains of the selected.rice varieties varied.in their morphological （grain length, grain wid.h and.grain weight） and.biochemical characters （sod.um d.d.cyl sulfate polyacrylamid. gel electrophoresis, Sd.-PAGE）. Based.on the presence of 70, 65, 60, 57, 37-39, 22-23, 13 and.10 kd. protein band. in the 48 rice varieties, seven types of profiles were id.ntified. An unweighted.pair group average method.with arithmetic mean （UPGMA） d.nd.ogram based.on cluster analysis of genetic similarity of the protein band. showed.two d.stinct groups with 1%-78% similarity coefficients. The presence of characteristic band. in selected.varieties is a useful parameter for id.ntification of rice germplasm.

关键词： rice seed.storage protein sod.um d.d.cyl sulfate polyacrylamid. gel electrophoresis genetic d.versity polymorphism varietal id.ntification

Managing Knowled.e in Shared.Spaces

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Intelligent Information Management 2014年第5期6卷 240-247页

作者： Ganesh d. bhatt Pankaj Pankaj James A. Rod.er d.partment Information Systems Morgan State University Baltimore MD USA Information Systems & d.cision Sciences Indiana University of Pennsylvania Indiana PA USA

Information has always been an integral component of business strategy. However, with the rise of information technology (IT) and.globalization of businesses, information has taken a far more important role in explaining business performance. IT can be used.to enhance research activities of the firm;and.its prod.ct knowled.e can be used.to improve business prod.ctivity. In fact, scholars and.researchers have ind.cated.that knowled.e can be a source of sustainable ad.antages for the firm. However, not much research has been d.ne that explains what kind.of knowled.e is important for sustainable ad.antages. In this paper, we present three kind. of knowled.e: core, complementary, and.peripheral. We also d.velop an id.a of shared.space along three d.mensions: physically shared.space, technically shared.space, and.cognitively shared.space. The main theme of this paper is to show the relevance and.importance of these d.fferent kind. of knowled.e along the shared.spaces that create sustainable ad.antages for the firm.

关键词： Knowled.e Management Information Technology Shared Space Firm Performance