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Bio-Design and Manufacturing 2019年第3期2卷 172-180页

作者： Maha Alruwaili Jose A.Lopez kevin mccarthy Emmanuel G.Reynaud Brian J.Rodriguez Conway Institute of Biomolecular and Biomedical Research University College DublinDublinIreland School of Physics University College DublinDublinIreland School of Biomolecular and Biomedical Science University College DublinDublinIreland

Extrusion-based 3D bioprinting is a direct deposition approach used to create three-dimensional(3D)tissue scaffolds typically comprising *** are hydrated polymer networks that are chemically or physically ***,3D bioprinting is performed in air,despite the hydrated nature of hydrogels and the potential advantage of using a liquid phase to provide cross-linking and otherwise functionalize the *** this work,we print gelatin alginate hydrogels directly into a cross-linking solution of calcium chloride and investigate the influence of nozzle diameter,distance between nozzle and surface,calcium chloride concentration,and extrusion rate on the dimensions of the printed *** hydrogel layer height was generally found to increase with increasing extrusion rate and nozzle distance,according to the increased volume extruded and the available space,*** addition,the hydrogel width was generally found to increase with decreasing nozzle distance and cross-linking concentration corresponding to confinement-induced spreading and low crosslinking regimes,***/height ratios of^1 were generally achieved when the nozzle diameter and distance were comparable above a certain cross-linking *** these relationships,biocompatible 3D multilayer structures were successfully printed directly into calcium chloride cross-linking solution.

关键词： Gelatin alginate Hydrogel Additive manufacturing 3D printing 3D bioprinting Biomaterials Extrusion Bioplotting

Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape

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四川生理科学杂志 2021年第1期43卷 86-86页

作者： kevin R mccarthy Center for Vaccine Research University of Pittsburgh School of Medicine Pittsburgh PA USA. Department of Microbiology and Molecular Genetics University of Pittsburgh School of Medicine Pittsburgh PA USA. Laboratory of Molecular Medicine Boston Children’s Hospital Harvard Medical School Boston MA USA. Department of Genetics Harvard Medical School Boston MA USA. Division of Pulmonary Allergy and Critical Care Medicine Department of Internal Medicine UPMC Pittsburgh PA USA. Division of Pulmonary Allergy and Critical Care Medicine Department of Medicine University of Pittsburgh School of Medicine Pittsburgh PA USA. VA Pittsburgh Healthcare System Pittsburgh PA USA. Division of Infectious Disease Department of Medicine University of Pittsburgh School of Medicine Pittsburgh PA USA. Division of Infectious Disease Department of Internal Medicine UPMC Pittsburgh PA USA.

Zoonotic pandemics,like that caused by SARS-CoV-2,can follow the spillover of animal viruses into highly susceptible human *** descendants have adapted to the human host and evolved to evade immune *** acquire substitutions more slowly than other RNA viruses,due to a proofreading *** the spike glycoprotein,we find recurrent deletions overcome this slow substitution rate.

关键词： glycoprotein overcome slowly

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烃源岩石油地球化学评价方法

国外测井技术 2017年第2期38卷 64-72页

作者： kevin mccarthy Katherine Rojas Martin Niemann Daniel Palmowski Kenneth Peters Artur Stankiewicz 美国得克萨斯州休斯敦法国Roissy-en-Franc 德国Aachen 美国加利福尼亚州Mill Valley 法国Clamart

每个油气远景区都源于烃源岩。每个远景区（无论是常规还是非常规远景区，也不管是石油还是天然气远景区）是否具有开发前景都取决于其烃源岩。如果不具备油气来源，开发远景区所必须研究的所有其他要素和过程都变得无关紧要。

关键词：地球化学评价烃源岩石油油气远景区油气来源天然气开发

Low-Cost Data Acquisition Systems for Photovoltaic System Monitoring and Usage Statistics

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Journal of Energy and Power Engineering 2017年第11期11卷 719-728页

作者： Sofia Fanourakis kevin Wang Patrick mccarthy Lihong (Heidi) Jiao School of Engineering Grand Valley State University Grand Rapids M149504 USA Forest Hills Central High School Grand Rapids MI 49546 USA

This paper presents the design of a low-cost DAS （data acquisition system） for monitoring a PV （photovoltaic） system＇s electrical quantities, battery temperatures, and state of charge of the battery. The electrical quantities are the voltages and currents of the solar panels, the battery, and the system loads. The system uses an Atmega328p microcontroller to acquire data from the PV system＇s charge controller. It also records individual load information using current sensing resistors along with a voltage amplification circuit and an analog to digital converter. The system is used in conjunction with a wall power DAS for the recording of regional power outages. Both DASs record data in microSD cards. The data have been successfully acquired from both systems and have been used to monitor the status of the PV system and the local power grid. As more data are gathered, it can be used for the maintenance and improvement of the PV system through analysis of the PV system＇s parameters and usage statistics.

关键词： Low-cost data acquisition PV system microcontroller.

Diagnostics for a troubled backbone:testing topological hypotheses of trapelioid lichenized fungi in a large-scale phylogeny of Ostropomycetidae(Lecanoromycetes)

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Fungal Diversity 2015年第4期73卷 239-258页

作者： Philipp Resl kevin Schneider Martin Westberg Christian Printzen Zdeněk Palice Göran Thor Alan Fryday Helmut Mayrhofer Toby Spribille Institute of Plant Sciences NAWI GrazUniversity of GrazHolteigasse 6A-8010 GrazAustria Department of Botany Swedish Museum of Natural HistoryP.O.Box 50007SE-10405 StockholmSweden Senckenberg Forschungsinstitut und Naturmuseum Senckenberganlage 25D-60325 Frankfurt am MainGermany Institute of Botany Academy of Sciences of the Czech RepublicZámek 125243 PrůhoniceCzech Republic Department of Botany Faculty of SciencesCharles University in PragueBenátská212801 Praha 2Czech Republic Department of Ecology Swedish University of Agricultural SciencesP.O.Box 7044SE-75007 UppsalaSweden Herbarium Department of Plant BiologyMichigan State UniversityEast LansingMI 48824USA Division of Biological Sciences University of Montana32 Campus DriveMissoulaMT 59812USA

Trapelioid fungi constitute a widespread group of mostly crust-forming lichen mycobionts that are key to understanding the early evolutionary splits in the Ostropomycetidae,the second-most species-rich subclass of lichenized *** uncertain phylogenetic resolution of the approximately 170 species referred to this group contributes to a poorly resolved backbone for the entire *** on a data set including 657 newly generated sequences from four ribosomal and four protein-coding gene loci,we tested a series of a priori and new evolutionary hypotheses regarding the relationships of trapelioid clades within *** found strong support for a monophyletic group of nine core trapelioid genera but no statistical support to reject the long-standing hypothesis that trapelioid genera are sister to Baeomycetaceae or ***,we can reject a sister group relationship to Ostropales with high *** data also shed light on several longstanding questions,recovering Anamylopsoraceae nested within Baeomycetaceae,elucidating two major monophyletic groups within trapelioids(recognized here as Trapeliaceae and Xylographaceae),and rejecting the monophyly of the genus *** transfer eleven species of the latter genus to Lambiella and describe the genus Parainoa to accommodate a previously misunderstood species of *** phylogenetic studies in Ostropomycetidae have invoked Bdivergence order^for drawing taxonomic conclusions on higher level *** data show that if backbone support is lacking,contrasting solutions may be recovered with different or added *** accordingly urge caution in concluding evolutionary relationships from unresolved phylogenies.

关键词： Ascomycota Fungi Lambiella Lecanoromycetes Ostropomycetidae Parainoa Paraphyly SOWH test Taxon sampling

Antitangling and manufacturable Fog Harps for high‐efficiency water harvesting

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Droplet 2023年第4期2卷 38-44页

作者： Jimmy K.Kaindu kevin R.Murphy Nicholas G.Kowalski Alexandra N.Jones Matthew Davis Fleming Brook S.Kennedy Jonathan B.Boreyko Department of Mechanical Engineering Virginia TechBlacksburgVirginiaUSA Department of Biomedical Engineering and Mechanics Virginia TechBlacksburgVirginiaUSA School of Architecture and Design Virginia TechBlacksburgVirginiaUSA Samscreen Inc. ConklinNew YorkUSA

Fog Harps harvest substantially more water than conventional mesh‐based ***,to date,all large‐scale Fog Harps have been impractically hand‐wound at low wire tensions and suffer from elastocapillary wire ***,we develop large‐scale and high‐tension Fog Harps that are manufacturable and *** Fog Harps retain the record‐setting fog harvesting efficiency(η≈17%)of their optimized scale‐model counterparts,while uniquely enabling practical real‐life *** was achieved by adapting the industrial process for making harp screens,a pre‐existing technology used for screening solid *** critical tension required to minimize wire tangling was rationalized by an improved elastocapillary tangling model.

关键词： harvesting capillary rational