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基础设施地震预警系统的范围分析

世界地震译丛 2015年第5期46卷 432-442页

作者： Theresa J.Brown Andjelka Kelic kevin L. Stamber Nancy S.Brodsky eric d.Vugrin Thomas F.Corbet Jr. William e.Fogleman Sharon L.O'Connor 谢辉李青梅宁夏回族自治区地震局

提供了评价假想地震预警系统,降低潜在灾害风险值的范围研究的成果。本研究根据的是对人口和基础设施降低灾害风险可采取的行动、采取每个行动需要多少时间和给定所采取行动的性质情况下虚报的潜在后果的分析。范围分析结果表明,可通过... 详细信息

提供了评价假想地震预警系统,降低潜在灾害风险值的范围研究的成果。本研究根据的是对人口和基础设施降低灾害风险可采取的行动、采取每个行动需要多少时间和给定所采取行动的性质情况下虚报的潜在后果的分析。范围分析结果表明,可通过改进现有的事件通知系统、对通知的个体响应和为当地规划绘制并利用更详细灾害风险图来降低灾害风险。根据地质条件和过程的现有知识所制定的详细地图和培训计划,将减少灾害风险分析结果部分的不确定性。地震的发震时间、震级和震中位置的不确定性以及虚报的潜在影响将对预警系统的价值提出重大的挑战。

关键词：地震预警系统基础设施潜在灾害灾害风险不确定性发震时间通知系统地质条件

delimiting species in Basidiomycota:a review

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Fungal diversity 2021年第4期109卷 181-237页

作者： Bin Cao danny Haelewaters Nathan Schoutteten dominik Begerow Teun Boekhout Admir J.Giachini Sergio P.Gorjón Nina Gunde-Cimerman kevin d.hy.e Martin Kemler Guo-Jie Li dong-Mei Liu Xin-Zhan Liu Jorinde Nuytinck Viktor Papp Anton Savchenko Kyryll Savchenko Leho Tedersoo Bart Theelen Marco Thines Michal Tomšovský Merje Toome-Heller Judith P.Urón Annemieke Verbeken Alfredo Vizzini Andrey M.Yurkov Juan Carlos Zamora Rui-Lin Zhao State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China Faculty of Science University of South Bohemia37005ČeskéBudějoviceCzech Republic Research Group Mycology Department of BiologyGhent University9000 GhentBelgium department of Botany and Plant Pathology College of AgriculturePurdue UniversityWest LafayetteIN 47907USA department of Geobotany Ruhr-Universität Bochum44801 BochumGermany Westerdijk Fungal Biodiversity Institute 3508 AD UtrechtThe Netherlands Institute of Biodiversity and ecosystem dynamics University of Amsterdam1090 GE AmsterdamThe Netherlands department of Microbiology Universidade Federal de Santa CatarinaFlorianópolisSC 88040-900Brazil department of Botany and Plant Physiology University of Salamanca37007 SalamancaSpain department of Biology Biotechnical FacultyUniversity of Ljubljana1000 LjubljanaSlovenia Center of excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand Innovative Institute of Plant Health Zhongkai University of Agriculture and EngineeringHaizhu DistrictGuangzhou 510225China CAS Key Laboratory for Plant diversity and Biogeography of east Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanChina Key Laboratory of Vegetable Germplasm Innovation and Utilization of Hebei Collaborative Innovation Center of VegetableCollege of HorticultureHebei Agricultural UniversityBaoding 071001Hebei ProvinceChina Institute of ecology Chinese Research Academy of Environmental SciencesBeijing 100012China Naturalis Biodiversity Center 2300 RA LeidenThe Netherlands department of Botany Institute of AgronomyHungarian University of Agriculture and Life Sciences1518 BudapestHungary Institute of ecology&earth Sciences University of Tartu51014 TartuEstonia department of Biological Sciences Butler UniversityIndianapolisIN 46219USA Center of Mycology and Microbiology University of Tartu14a Ravila50411 TartuEstonia Senckenberg Biodiversity and Climate Researc

Species delimitation is one of the most fundamental processes in *** undertakings,for instance,require explicit species concepts and criteria for species delimitation in order to be relevant and ***,a perfect species concept does not exist for ***,we review the species concepts commonly used in Basidiomycota,the second largest phylum of Fungi that contains some of the best known species of mushrooms,rusts,smuts,and jelly *** general,best practice is to delimitate species,publish new taxa,and conduct taxonomic revisions based on as many independent lines of evidence as possible,that is,by applying a so-called unifying(or integrative)conceptual ***,the types of data used vary considerably from group to *** this reason we discuss the different classes of Basidiomycota,and for each provide:(i)a general introduction with difficulties faced in species recognition,(ii)species concepts and methods for species delimitation,and(iii)community recommendations and conclusions.

关键词： Biological species concept Morphological species concept Phylogenetic species concept Taxonomy

The Global Soil Mycobiome consortium dataset for boosting fungal diversity research

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Fungal diversity 2021年第6期111卷 573-588页

作者： Leho Tedersoo Vladimir Mikryukov Sten Anslan Mohammad Bahram Abdul Nasir Khalid Adriana Corrales Ahto Agan Aída-M.Vasco-Palacios Alessandro Saitta Alexandre Antonelli Andrea C.Rinaldi Annemieke Verbeken Bobby P.Sulistyo Boris Tamgnoue Brendan Furneaux Camila duarte Ritter Casper Nyamukondiwa Cathy Sharp César Marín d.Q.dai daniyal Gohar dipon Sharmah elisabeth Machteld Biersma erin K.Cameron eske de Crop eveli Otsing evgeny A.davydov Felipe e.Albornoz Francis Q.Brearley Franz Buegger Genevieve Gates Geoffrey Zahn Gregory Bonito Indrek Hiiesalu Inga Hiiesalu Irma Zettur Isabel C.Barrio Jaan Pärn Jacob Heilmann-Clausen Jelena Ankuda John Y.Kupagme Joosep Sarapuu Jose G.Maciá-Vicente Joseph djeugap Fovo József Geml Juha M.Alatalo Julieta Alvarez-Manjarrez Jutamart Monkai Kadri Põldmaa Kadri Runnel Kalev Adamson Kari A.Bråthen Karin Pritsch Kassim I.Tchan Kęstutis Armolaitis kevin d.hy.e kevin K.Newsham Kristel Panksep Lateef A.Adebola Louis J.Lamit Malka Saba Marcela eda Silva Cáceres Maria Tuomi Marieka Gryzenhout Marijn Bauters Miklós Bálint Nalin Wijayawardene Niloufar Hagh-doust Nourou S.Yorou Olavi Kurina Peter e.Mortimer Peter Meidl RHenrik Nilsson Rasmus Puusepp Rebeca Casique-Valdés Rein drenkhan Roberto Garibay-Orijel Roberto Godoy Saleh Alfarraj Saleh Rahimlou Sergei Põlme Sergey V.dudov Sunil Mundra Talaat Ahmed Tarquin Netherway Terry W.Henkel Tomas Roslin Vladimir e.Fedosov Vladimir G.Onipchenko WAerandi Yasanthika Young Woon Lim Meike Piepenbring darta Klavina Urmas Kõljalg Kessy Abarenkov Mycology and Microbiology Center University of TartuTartuEstonia Institute of ecology and earth Sciences TartuEstonia department of ecology Swedish University of Agricultural SciencesUppsalaSweden department of Botany University of the PunjabQuaid-e-Azam CampusLahorePakistan Centro de Investigaciones en Microbiología y Biotecnología-UR(CIMBIUR) Facultad de Ciencias NaturalesUniversidad del RosarioBogotáColombia Grupo de Microbiología Ambiental y BioMicro Escuela de MicrobiologíaUniversidad de Antioquia UdeAMedellínColombia department of Agricultural Food and Forest SciencesUniversity of PalermoPalermoItaly Royal Botanic Gardens SurreyUK department of Biomedical Sciences University of CagliariCagliariItaly Research Group Mycology Department of BiologyGhent UniversityGhentBelgium department of Biomedicine Indonesia International Institute for Life SciencesJakartaIndonesia Plant Pathology and Agricultural Zoology Research Unit Department of Plant ProtectionFaculty of Agronomy and Agricultural SciencesUniversity of DschangDschangCameroon department of ecology and Genetics Uppsala UniversityUppsalaSweden eukaryotic Microbiology University of Duisburg-EssenEssenGermany department of Biological Sciences and Biotechnology Botswana International University of Science and TechnologyPalapyeBotswana Natural History Museum of Zimbabwe BulawayoZimbabwe Institute of Botany Czech Academy of SciencesPrůhoniceCzech Republic Center for Yunnan Plateau Biological Resources Protection and Utilization College of Biological Resource and Food EngineeringQujing Normal UniversityQujingPeople’s Republic of China department of Botany Jawaharlal Nehru Rajkeeya MahavidyalayaPondicherry UniversityPort BlairIndia British Antarctic Survey NERCCambridgeUK Natural History Museum of denmark University of CopenhagenCopenhagenDenmark department of environmental Science Saint Mary’s UniversityHalifaxNSCanada Altai State University BarnaulRussia CSIRO Land and Water WembleyWAAustralia department of N

Fungi are highly important biotic components of terrestrial ecosystems,but we still have a very limited understanding about their diversity and *** data article releases a global soil fungal dataset of the Global Soil Mycobiome consortium(GSMc)to boost further research in fungal diversity,biogeography and *** dataset comprises 722,682 fungal operational taxonomic units(OTUs)derived from PacBio sequencing of full-length ITS and 18S-V9 variable regions from 3200 plots in 108 countries on all *** plots are supplied with geographical and edaphic *** OTUs are taxonomically and functionally assigned to guilds and other functional *** entire dataset has been corrected by excluding chimeras,index-switch artefacts and potential *** dataset is more inclusive in terms of geographical breadth and phylogenetic diversity of fungi than previously published *** GSMc dataset is available over the PlutoF repository.

关键词： Soil fungi Global dataset PacBio sequencing Fungal richness

An early-morning gene network controlled by phytochromes and cryptochromes regulates photomorphogenesis pathways in Arabidopsis

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Molecular Plant 2021年第6期14卷 983-996页

作者： Martin Balcerowicz Mahiar Mahjoub duy Nguyen Hui Lan dorothee Stoeckle Susana Conde Katja e.Jaeger Philip A.Wigge daphne ezer Sainsbury Laboratory University of CambridgeCambridgeUK department of Statistics University of WarwickCoventryUK Alan Turing Institute LondonUK Leibniz-Institute of Vegetable and Ornamental Crops(IGZ) 14979 GroßbeerenGermany Institute of Biochemistry and Biology University of PotsdamPotsdamGermany department of Biology University of YorkYork YO105DDUK Royal Prince Alfred Hospital Central Clinical SchoolUniversity of SydneyCamperdownNSWAustralia Plant Systems Physiology Institute for Water and Wetland ResearchRadboud UniversityNijmegenthe Netherlands Zhejiang Normal University Wucheng DistrictJinhuaZhejiangChina department of Plant and Microbial Biology University of ZurichZurichSwitzerland

Light perception at dawn plays a key role in coordinating multiple molecular processes and in entraining the plant circadian *** Arabidopsis mutant lacking the main photoreceptors,however,still shows clock entrainment,indicating that the integration of light into the morning transcriptome is not well *** this study,we performed a high-resolution RNA-sequencing time-series experiment,sampling every 2 min beginning at *** parallel experiments,we perturbed temperature,the circadian clock,photoreceptor signaling,and chloroplast-derived light *** used these data to infer a gene network that describes the gene expression dynamics after light stimulus in the morning,and then validated key *** sampling time points at high density,we are able to identify three light-and temperature-sensitive bursts of transcription factor activity,one of which lasts for only about 8 *** and cryptochrome mutants cause a delay in the transcriptional bursts at dawn,and completely remove a burst of expression in key photomorphogenesis genes(hy5 and BBX family).Our complete network is available online(http://***/∼de656/dawnBurst/***).Taken together,our results show that phytochrome and cryptochrome signaling is required for fine-tuning the dawn transcriptional response to light,but separate pathways can robustly activate much of the program in their absence.

关键词： BBX family cryptochrome dawn hy5 network morning phytochrome transcriptome

ILG1:在纽约实验室大肠杆菌菌株中发现一种与噬菌体整合酶相似的新p4(英文)

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第四军医大学学报 2002年第14期23卷 1249-1252页

作者：田文志白慧玲马远方 kevin Chua Warren Strober Charles C Chu 北海岸大学附属医院纽约11030 河南大学医学院分子免疫学实验室河南开封475001

目的　免疫球蛋白类别转换在生发中心 B细胞中进行 ,从而 B细胞由产生 Ig M转换到产生其他类别的免疫球蛋白如 Ig G,Ig A,Ig e.目前导致类别转换的机制还不清楚 .我们试图克隆参与类别转换的基因 .方法　原发性免疫缺陷患者 B细胞不能... 详细信息

目的　免疫球蛋白类别转换在生发中心 B细胞中进行 ,从而 B细胞由产生 Ig M转换到产生其他类别的免疫球蛋白如 Ig G,Ig A,Ig e.目前导致类别转换的机制还不清楚 .我们试图克隆参与类别转换的基因 .方法　原发性免疫缺陷患者 B细胞不能进行类别转换 ,而正常细胞则可以 .据此 ,我们将患者与正常人的 B细胞在同一条件下分别培养以诱导类别转换 .从培养的细胞中分别提取 RNA,并反转录成 c dNA,由此制备扩增物 (amplicon) .最后将来源于患者 B细胞的扩增物与正常人 B细胞的扩增物混合在一起 ,在一定条件下进行剔除杂交 .经 5轮剔除杂交以后 ,将剔除共同基因以后的剩余物进行克隆 .经筛选以后将阳性克隆物进行测序及序列分析 .结果　在所有克隆中 ,我们发现一个新基因 ,命名为整合酶样基因 - 1.后证实 ,该基因来源于实验室细菌株 TOP10 F'序列分析表明 ,IL G1具有原核基因特性 ,但缺乏真核细胞的基因特性 .在 dNA水平 ,IL G1与任何基因都不具有同源性 ,但在蛋白水平 ,它与来源于溶原性 p4噬菌体的整合酶具有高达 5 8%的同源性 ,我们认为 IL G1定居于一个新的溶原性 p4原噬菌体 Φ- TOP10 *** G1的催化活性区具有高度保守特性 ,因为活性区的关键氨基酸残基是保守的 ,这包括高度保守的 R- H- R- Y结构 .

关键词：大肠杆菌菌株噬菌体整合酶 p4 细菌遗传重组

One stop shop Ⅱ:taxonomic update with molecular phylogeny for important phytopathogenic genera:26–50(2019)

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Fungal diversity 2019年第1期94卷 41-129页

作者： Ruvishika S.Jayawardena kevin d.hy.e Rajesh Jeewon Masoomeh Ghobad-Nejhad dhanushka N.Wanasinghe NingGuo Liu Alan J.L.Phillips Jose Ribamar COliveira-Filho Gladstone Ada Silva Tatiana B.Gibertoni P.Abeywikrama L.M.Carris K.W.T.Chethana A.J.dissanayake S.Hongsanan S.C.Jayasiri A.R.McTaggart R.H.Perera K.Phutthacharoen K.G.Savchenko R.G.Shivas Naritsada Thongklang Wei dong dePing Wei Nalin NWijayawardena Ji-Chuan Kang The engineering Research Center of Southwest Biopharmaceutical Resources Ministry of EducationGuizhou UniversityGuiyang 550025People’s Republic of China Center of excellence in Fungal Research Mae Fah Luang UniversityChiang RaiThailand Key Laboratory for Plant diversity and Biogeography of east Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201People’s Republic of China department of Health Sciences Faculty of ScienceUniversity of MauritiusReduitMauritius department of Biotechnology Iranian Research Organization for Science and Technology(IROST)P.O.Box 15815-3538Tehran 15819Iran World Agroforestry Centre East and Central AsiaKunming 650201YunnanPeople’s Republic of China Universidade de Lisboa Faculdade de CienciasBiosystems and Integrative Sciences Institute(BioISI)Campo Grande1749-016 LisbonPortugal departamento de Micologia Universidade Federal de PernambucoAvenida da EngenhariaS/N-Cidade UniversitariaRecifePE 50740-600Brazil Beijing Key Laboratory of environmet Friendly Management on Fruit disease and Pests in North China Institute of Plant and Environment ProtectionBeijing Academy of Agriculture and Forestry SciencesBeijing 100097People’s Republic of China department of Plant Pathology Washington State UniversityPullmanWA 99164USA College of Life Science and Oceanography ShenZhen University1068Nanhai AvenueNanshanShenzhen 518055China Queensland Alliance for Agriculture and Food Innovation The University of QueenslandBrisbaneQLD 4001Australia department of Biological Sciences Butler UniversityIndianapolisIN 46208USA Centre for Crop Health University of Southern QueenslandToowoombaQLD 4350Australia department of entomology and Plant Pathology Faculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Faculty of Agriculture National Resources and EnvironmentNaresuan UniversityPhitsanulok 65000Thailand

This paper is the second in a series focused on providing a stable platform for the taxonomy of phytopathogenic *** focuses on 25 phytopathogenic genera:Alternaria,Bipolaris,Boeremia,Botryosphaeria,Calonectria,Coniella,Corticiaceae,Curvularia,elsinoe,entyloma,erythricium,Fomitiporia,Fulviformes,Laetisaria,Limonomyces,Neofabraea,Neofusicoccum,Phaeoacremonium,Phellinotus,Phyllosticta,Plenodomus,Pseudopyricularia,Tilletia,Venturia and Waitea,using recent molecular data,up to date names and the latest taxonomic *** each genus a taxonomic background,diversity aspects,species identification and classification based on molecular phylogeny and recommended genetic markers are *** this study,varieties of the genus Boeremia have been elevated to species ***,Bipolaris,Curvularia,Neofusicoccum and Phyllosticta that were included in the One Stop Shop 1 paper are provided with updated entries,as many new species have been introduced to these genera.

关键词： Boeremia dNA barcodes endophytes Plant pathology Systematics Taxonomy

氯吡格雷的使用与药物洗脱支架植入后远期临床结果

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美国医学会杂志（中文版） 2007年第3期26卷 131-139页

作者： eric L eisenstein, dBA kevin J. Anstrom, Phd david F. Kong, Md Linda K. Shaw, MS Robert H. Tuttle, MSPH daniel B. Mark, Md, MPH Judith M. Kramer, Md, MS Robert A. Harrington, Md david B. Matchar, Md david e. Kandzari, Md 1 eric d. Peterson, Md, MPH kevin A. Schulman, Md Robert M. Califf, Md 李呈亿（译） david e. Kandzari, Md department of Medicine duke Clinical Research Institute Biostatistics and Bioinformatics Duke Clinical Research Institute duke University Medical Center Duke Clinical Research Institute duke Translational Medicine Institute Durham NC the duke Center for Clinical Health Policy Research Durham NC 不详

背景：近来的冠状动脉内药物洗脱支架研究提示，现行的抗血小板治疗方案可能并不足以预防后期支架内血栓形成。目的：于接受药物洗脱支架（drug-eluting stents，deSs）和裸金属支架（bare-metal stents，BMSs）治疗的冠状动脉病患者中... 详细信息

背景：近来的冠状动脉内药物洗脱支架研究提示，现行的抗血小板治疗方案可能并不足以预防后期支架内血栓形成。目的：于接受药物洗脱支架（drug-eluting stents，deSs）和裸金属支架（bare-metal stents，BMSs）治疗的冠状动脉病患者中评估氯吡格雷使用与患者远期结果的关系。设计、地点及患者：于连续患者中进行观察性研究。患者于2000年1月1日至2005年7月31日在杜克心脏治疗中心（一家位于北卡罗来纳州达累姆市的三级治疗中心）接受冠状动脉内支架治疗。于6、12、24个月时进行随访，直至2006年9月7日。研究人群包括4666例最初接受BMS（n=3165）或deS（n=1501）经皮冠状动脉介入治疗的患者。对随访6和12个月没有事件（没有死亡、心肌梗死或血管重建手术）的患者进行界标分析（landmark analysis）。在这些时间点上根据支架类型以及自我报告之氯吡格雷的使用情况将患者分为4组：deS使用氯吡格雷组、deS不用氯吡格雷组、BMS使用氯吡格雷组以及BMS不用氯吡格雷组。主要观测指标：随访24个月时死亡、非致命性心肌梗死以及死亡或心肌梗死之复合终点。结果：在6个月时没有事件发生的deS组患者（637例使用、579例未使用氯吡格雷）中，氯吡格雷的使用是随访24个月校正死亡率较低（使用2．0％比未使用5．3％；差异，-3．3％；95％CI，-6．3％至-0．3％；P=0．03）以及死亡或心肌梗死发生率较低（3．1％比7．2％；差异，-4．1％；95％CI，-7．6％至-0．6％；P=0．02）的显著预测指标。然而，在BMS组患者中（417例使用、1976例未用氯吡格雷），死亡（3．7％比4．5％；差异，-0．7％；95％CI，-2．9％至1．4％；P=0．50）以及死亡或心肌梗死发生率（5．5％比6．0％；差异，-0．5％；95％CI，-3．2％至2．2％；P：0．70）没有差异。在12个月随访没有事件发生的deS组患者（252例使用、276例未用氯吡格雷）中，氯吡格雷的使用依然可以预测24个月死亡（0％比3．5％；差异，-3．5％；95％CI，-5．9％至-1．1％；P=0．004）以及死亡或心肌梗死发生率（0％比4．5％；差异，-4．5％；95％CI，-7．1％至-1．9％；P〈0．001）较低。然而，在BMS组患者中（346例使用、1644例未用氯吡格雷），在死亡（3．3％比2．7％；差异，0．6％；95％CI，1．5％至2．8％；P=0．57）以及死亡或心肌梗死（4．7％比3．6％；差异，1．0％；95％CI，-1．6％至3．6％；P=0．44）发生方面，依然没有差异。结论：在接受deS治疗的患者中，延长氯吡格雷的使用可以使死亡以及死亡或心肌梗死的发生率下降。然而，使用氯吡格雷的适宜期限只能通过大型临床随机试验确定。

关键词：药物洗脱支架氯吡格雷临床结果经皮冠状动脉介入治疗植入后冠状动脉内心肌梗死支架内血栓形成

铅对仔鼠行为功能影响的实验研究(二)──雄性小鼠接触铅对仔鼠行为功能的影响

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毒理学杂志 1994年第S1期16卷 7-9页

作者：王静赵力军杨树媛李尊爱天津劳动卫生职业病研究所

我们应用行为畸胎学的方法，建立了对雄性昆明种小鼠进行小剂量慢性醋酸铅染毒的动物模型。染毒剂量为１０００ｍｇ／１、５００ｍｇ／１、５０ｍｇ／１醋酸铅水溶液。染毒时间为５０天。染毒方式为自由饮用。观察其仔鼠的行为功能改变... 详细信息

我们应用行为畸胎学的方法，建立了对雄性昆明种小鼠进行小剂量慢性醋酸铅染毒的动物模型。染毒剂量为１０００ｍｇ／１、５００ｍｇ／１、５０ｍｇ／１醋酸铅水溶液。染毒时间为５０天。染毒方式为自由饮用。观察其仔鼠的行为功能改变。结果发现：５００ｍｇ／Ｌ组（血铅■＝３８．０７７　ｇ／ｄ１）和１０００ｍｇ／Ｌ组（血铅■＝６１．０５６　ｇ／ｄ１）雄性小鼠精子畸形率明显高于正常对照组，但其仔代的行为功能除个别指标（平面翻正反射）外，无明显改变。提示，本实验条件下，铅对仔鼠行为功能的影响与雄性亲代接触铅关系不大。

关键词：铅雄性小鼠仔代行为功能

Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins

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Interferon-mediated reprogramming of membrane cholesterol to...