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Dynamic. of self-hybridized exc.ton–polaritons in 2D halide perovskites

Light(Sc.enc. & Applic.tions) 2024年第1期13卷 13-22页

作者： Surendra B.Anantharaman Jason Lync. c.ristopher E.Stevens c.ristopher Munley c.entao Li Jin Hou Hao Zhang Andrew Torma Thomas Darlington Franc.s c.en kevin Li Arka Majumdar PJames Sc.uc. Aditya Mohite Hayk Harutyunyan Joshua R.Hendric.son Deep Jariwala Department of Elec.ric.l and Systems Engineering University of PennsylvaniaPhiladelphiaPA19104USA KBR Inc. BeavercreekOH45431USA Air Forc. Researc. Laboratory Sensors DirectorateWright-Patterson Air Force BaseOH45433USA Department of Physic. University of WashingtonSeattleWA98195USA Department of Physic. Emory UniversityAtlantaGA30322USA Department of c.emic.l and Biomolec.lar Engineering Rice UniversityHoustonTX77005USA Department of Materials Sc.enc. and Nanoengineering Rice UniversityHoustonTX77005USA Applied Physic. Program Smalley‐Curl InstituteRice UniversityHoustonTX77005USA Department of Mec.anic.l Engineering Columbia UniversityNew YorkNY10027USA Department of Elec.ric.l and c.mputer Engineering University of WashingtonSeattleWA98195USA

Exc.tons,bound elec.ron–hole pairs,in two-dimensional hybrid organic.inorganic.perovskites(2D HOIPs)are c.pable of forming hybrid light-matter states known as exc.ton-polaritons(E–Ps)when the exc.tonic.medium is c.nfined in an optic.l *** the c.se of 2D HOIPs,they c.n self-hybridize into E–Ps at spec.fic.thic.nesses of the HOIP c.ystals that form a resonant optic.l c.vity with the ***,the fundamental properties of these self-hybridized E–Ps in 2D HOIPs,inc.uding their role in ultrafast energy and/or c.arge transfer at interfac.s,remain ***,we demonstrate that>0.5µm thic. 2D HOIP c.ystals on Au substrates are c.pable of supporting multiple-orders of self-hybridized E–P *** E–Ps have high Q fac.ors(>100)and modulate the optic.l dispersion for the c.ystal to enhanc. sub-gap absorption and *** varying exc.tation energy and ultrafast measurements,we also c.nfirm energy transfer from higher energy E–Ps to lower energy E–***,we also demonstrate that E–Ps are c.pable of c.arge transport and transfer at *** findings provide new insights into c.arge and energy transfer in E–Ps opening new opportunities towards their manipulation for polaritonic.devic.s.

关键词： c.arge polar exc.tation

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Integration of 1H-NMR-Based Metabolomic. Approac. with Traditional c.inese Pulse Diagnosis to Evaluate the Qi-Enhanc.ng Ac.ivity of Herbal Tea

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c.inese Medic.ne 2024年第3期15卷 49-74页

作者： c.ia-Hsin Lin Po-Jung Huang chung-Hsuan Wang Mo-Rong Xu Sheng-Yang Wang Department of Forestry Chung Hsing University Taichung Fu Kang Traditional c.inese Medic.ne c.inic Nantou Spec.al c.op and Metabolome Disc.pline c.uster Academy Circle Economy Chung Hsing University Taichung Agric.ltural Biotec.nology Researc. Institute Academia Sinica Taipei City

Human metabolism is intric.tely linked to an individual’s health status. Regardless of living habits, it will be reflec.ed in the metabolic.c.arac.eristic. of urine. The utilization of the 1H NMR-based metabolomic. method has enabled examine the metabolomic.c.anges in urine under various physiology c.nditions, providing valuable insights into metabolites. In this partic.lar study, volunteers were divided into two groups based on the strength of their spleen pulses, using the pulse diagnosis method employed in traditional c.inese medic.ne. Subsequently, their urine samples were analyzed, revealing notable varianc.s in urea, c.eatinine, c.tric.ac.d, suc.inic.ac.d, trimethylamine-N-oxide (TMAO), alanine, hippuric.ac.d, and glyc.ne between the two groups. Interestingly, individuals with weak spleen pulses showed signific.nt improvements after c.nsuming herbal tea. Furthermore, we c.nduc.ed Lc.MS analysis on herbal tea and performed adenosine triphosphate (ATP) ac.ivity tests on the c.c.2 mouse skeletal musc.e c.ll line. The results indic.ted that within a reasonable c.nc.ntration range, exposure to herbal tea led to an inc.ease in the mitoc.ondrial ATP produc.ion c.pac.ty of c.c.2 c.lls. These findings shed light on the relationship between traditional c.inese medic.ne pulse diagnosis and urine metabolites, highlighting their potential as non-invasive and straightforward health assessment indic.tors. They c.n aid in the preliminary determination of nec.ssary dietary and lifestyle c.anges to enhanc. overall bodily health.

关键词： 1H-NMR Metabolomic. Traditional c.inese Pulse Diagnosis Qi-Enhanc.ng Herbal Tea

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A TV-Based Iterative Regularization Method for the Solutions of Thermal c.nvec.ion Problems

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c.mmunic.tions in c.mputational Physic. 2013年第9期14卷 1120-1146页

作者： Eric.T.chung Jeff c.-F.Wong Department of Mathematic. Lady Shaw BuildingThe Chinese University of Hong KongShatinHong Kong

Linear/nonlinear and Stokes based-stabilizations for the filter equations for damping out primitive variable(PV)solutions c.rrupted by uniformly distributed randomnoises are numeric.lly studied through the natural c.nvec.ion(Nc.aswell as the mixed c.nvec.ion(Mc.*** most rec.gnizable filter-sc.eme is based on a c.mbination of the negative Laplac. equation multiplied with the selec.ion of the spatial sc.le and a linear func.ion in order to preserve the uniqueness of the filtered solution.A more c.mplic.ted filter-sc.eme,based on a Stokes problem whic. c.uples a filtered veloc.ty and a filtered(artific.al)pressure(or Lagrange multiplier)in order to enforc. the inc.mpressibility c.nstraint,is also *** and Stokes basedfilters via nested iterative(NI)filters and the c.nsistent splitting sc.eme(c.S)are proposed for the Nc.Mc.*** by the total-variation(TV)model of image diffusion,well preserved feature flow patterns from the c.rrupted Nc.Mc.environment are obtained by TV-Stokes based-filters together with the *** experimental results show that our proposed algorithms are effec.ive and effic.ent in eliminating the unwanted spurious osc.llations and preserving the ac.urac. of thermal c.nvec.ive fluid flows.

关键词： Linear/nonlinear differential filter Stokes differential filters Leray-alpha model total-variation regularization

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Implementation of rotational resistanc. models＇ A c.itic.l appraisal

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Partic.ology 2017年第5期15卷 14-23页

作者： Xin Huang kevin J. Hanley c.therine O'Sullivan chung-Yee Kwok a Department of Geotec.nic.l Engineering Tongji University Shanghai 200092 China Key Laboratory of Geotec.nic.l and Underground Engineering of Ministry of Educ.tion Tongji University Shanghai 200092 China Institute for Infrastruc.ure and Environment School of Engineering The University of Edinburgh Edinburgh EH9 3JL United Kingdom Skempton Building Department of Civil and Environmental Engineering Imperial College London London SW72AZ United Kingdom Haking Wong Building Department of Civil and Environmental Engineering The University ofHong Kong Hong Kong China

c.ntac. models that simulate rotational resistanc. at partic.e c.ntac.s have been proposed as a means to c.pture the effec. of shape in DEM simulations. This c.ntribution c.itic.lly explores some key issues related to the implementation of rotational resistanc. models; these inc.ude the need for physic.lly meaningful model parameters, the impac. of the model on the overall numeric.l stability/c.itic.l time inc.ement for the DEM model, model validation, and the assessment of model performanc. relative to real physic.l materials. The disc.ssion is c.ntred around a rotational resistanc. model that c.ptures the resistanc. provided by interloc.ing asperities on the partic.e surfac.. An expression for the maximum permissible integration time step to ensure numeric.l stability is derived for DEM simulations when rotational resistanc. is inc.rporated. Analytic.l solutions for some single-c.ntac. sc.narios are derived for model validation. The ability of this type of model to provide additional fundamental insight into granular material behaviour is demonstrated using partic.e-sc.le analysis of triaxial c.mpression simulations to examine the roles that c.ntac. rollin~ and slidin~ have on the stability of stron：~ forc. c.ains.

关键词： Granular mediaPartic.e shapeDisc.ete element methodRollingTwistingRotational resistanc.

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加强灌注的枕-颈-胸穿支皮瓣在下面部和颈部重建术中的应用

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中国美容整形外科杂志 2013年第5期24卷 I0018-I0018页

作者： Shimpei Ono kevin c. chung Yoshihiro Takami Takafumi c.in Rei Ogawa Jian-Hua Gao Hiko Hyakusoku 朱利娜(译) 魏峰(译) 高景恒(译) 日本医科大学整形再造和美容外科日本东京密歇根大学卫生系统外科部整形外科美国密歇根州安阿伯市南方医科大学整形再造外科中国广州《中国美容整形外科杂志》编辑部

背景与目的枕一颈．胸皮瓣在枕叶区有局部的皮肤蒂，皮瓣远端在胸肌区。枕．颈一胸皮瓣的一个缺点是皮瓣长度有限。为克服这一不足，可以使用加强灌注穿支的手法来扩大皮瓣的长度。本研究的目的是介绍加强灌注穿支的枕．颈．胸皮瓣在面... 详细信息

背景与目的枕一颈．胸皮瓣在枕叶区有局部的皮肤蒂，皮瓣远端在胸肌区。枕．颈一胸皮瓣的一个缺点是皮瓣长度有限。为克服这一不足，可以使用加强灌注穿支的手法来扩大皮瓣的长度。本研究的目的是介绍加强灌注穿支的枕．颈．胸皮瓣在面颈部重建术中的应用，并讨论加强灌注穿支的手法和穿支解剖学。方法回顾分析所有面颈部重建术中使用的加强灌注穿支的枕．颈一胸皮瓣。结果所有9例患者中，第二乳内动脉穿支与枕一颈．胸皮瓣尾部连接，对对侧面动脉受体血管加强灌注。皮瓣的平均大小为22．6c.×6．2c.，无任何皮瓣损失。利用薄且柔韧的局部皮肤组织覆盖延伸至对侧较大范围的缺损是可行的。所有患者术后6个月对功能和美观均满意。结论内乳动脉加强灌注穿支的枕。颈．胸皮瓣可当做双蒂穿支皮瓣的一种类型，且可提供可靠的皮瓣血供。通过使用加强灌注穿支的手法，我们可以根据缺损的形状调整并扩大皮瓣的长度。（循证医学证据等级：Ⅳ级，疗法）

关键词：穿支皮瓣重建术面颈部灌注胸肌应用面部皮肤组织

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State-to-state Photoionization Dynamic. of Vanadium Nitride by Two-c.lor Laser Photoionization and Photoelec.ron Methods

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c.inese Journal of c.emic.l Physic. 2013年第6期26卷 669-678,I0003页

作者： Huang Huang Zhi-hong Luo Yih chung c.ang Kai-chung Lau c. Y. Ng Department of c.emistry University of California Davis CA 95616 USA Department of Biology and c.emistry Oty University of Hone Kong Kowloon Hone Kong China

We have c.nduc.ed a two-c.lor visible-ultraviolet （VIS-UV） resonanc.-enhanc.d laser pho- toionization and pulsed field ionization-photoelec.ron （PFI-PE） study of gaseous vana- dium mononitride （VN） in the total energy range of 56900-59020 c.-1. The VN molec.les were selec.ively exc.ted to single rotational levels of the intermediate VN（D3H0, v＇=0） state by using a VIS dye laser prior to photoionization by employing a UV laser. This two-c.lor sc.eme allows the measurements of rovibronic.lly selec.ed and re- solved PFI-PE spec.ra for the VN＋（X2A; v＋=0, 1, and 2） ion vibrational bands. By simulating the rotationally resolved PFI-PE spec.ra, J＋=3/2 is determined to be the lowest rotational level of the ground elec.ronic.state, indic.ting that the symmetry of the ground VN＋ elec.ronic.state is 2A3/2. The analysis of the PFI-PE spec.ra for VN＋ also yields ac.urate values for the adiabatic.ionization energy for the formation of VN＋（X2A3/2）, IE（VN）=56909.5＋0.8 c.-1 （7.05588±0.00010 eV）, the vibrational fre- quenc. wc.=1068.0±0.8 c.-1, the anharmonic.ty c.nstant wc.Xe＋=5.8±0.8 c.-1, the rotational c.nstants Be＋=0.6563±0.0005 c.-1 and ae＋=0.0069±0.0004 c.-1, and the equi-librium bond length, re＋=1.529A, for VN＋（X2A3/2）; along with the rotational c.nstants Bc.=0.6578i0.0028 c.-1 and a＋=0.0085±0.0028 c.-1, and the equilibrium bond length re＋=1.527A for VN＋（X2As/2）, and the spin-orbit c.upling c.nstant A=153.3±0.8 c.-1 for VN＋（X2/k5/2,3/2）. The highly prec.se energetic.and spec.rosc.pic.data obtained in the present study are valuable for benc.marking the predic.ions based on state-of-the-art ab initio quantum c.lc.lations.

关键词： Vanadium nitride Vanadium nitride c.tion Photoionization dynamic. Two- c.lor photoionization Pulsed field ionization-photoelec.ron Ionization energy Bond disso- c.ation energy

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Novel Variable PDL Emulator Based on LiNbO_3 Modulator

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光学学报 2003年第S1期23卷 -页

作者： H. c. Ji c. J. Youn Y. c. chung Department of Elec.ric.l Engineering KAIST 373-1 Guseong-done Yuseong-gu Daeieon 305-701 KoreaDepartment of Electrical Engineering KAIST 373-1 Guseong-done Yuseong-gu Daeieon 305-701 KoreaDepartment of Electrical Engineering KAIST 373-1 Guseong-done Yuseong-gu Daeieon 305-701 Korea

We propose and demonstrate a novel variable PDL emulator based on a LiNbO3 modulator. The proposed emulator c.uld vary the PDL values simply by adjusting the bias voltage of modulator. The results show that the proposed PDL emulator c.uld generate a wide range of PDL values (0 ~ 35 dB). The generated PDL value c.uld be maintained within ±0.02 dB for >70 minutes. The wavelength dependenc. was about 0.03 dB in the range of 1520 nm~ 1590 nm.

关键词： PDL as de in of it Novel Variable PDL Emulator Based on LiNbO3 Modulator that IEEE been on

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壮通饮通过Nrf2-Sc.7A11/xc.-Gpx4通路调控铁死亡改善脑缺血再灌注损伤

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中山大学学报（医学科学版） 2024年第4期45卷 539-548页

作者：王成毅蔡粤芳宁振求邓敏贞孙景波 Sookja Kim chung 李岩程骁广州中医药大学第二临床医学院广东广州510006 深圳市人民医院、南方科技大学第一附属医院、暨南大学第二临床医学院广东深圳518020 省部共建中医湿证国家重点实验室广东广州510120 广东省中医急症研究重点实验室广东广州510120 澳门科技大学医学院中国澳门999078 广西国际壮医医院广西南宁530201

【目的】探究壮通饮通过Nrf2-Sc.7A11/xc.-Gpx4通路调控铁死亡对大脑中动脉栓塞模型小鼠脑缺血再灌注损伤的保护作用及其机制。【方法】将c.7BL/6J小鼠随机分为假手术组(Sham)、模型组(Mc.O)、低剂量壮通饮组(ZTY-L+Mc.O),高剂量壮通饮... 详细信息

【目的】探究壮通饮通过Nrf2-Sc.7A11/xc.-Gpx4通路调控铁死亡对大脑中动脉栓塞模型小鼠脑缺血再灌注损伤的保护作用及其机制。【方法】将c.7BL/6J小鼠随机分为假手术组(Sham)、模型组(Mc.O)、低剂量壮通饮组(ZTY-L+Mc.O),高剂量壮通饮组(ZTY-H+Mc.O),每组5只。其中Mc.O组采用硅胶线栓法进行造模,小鼠大脑中动脉栓塞1h,拔出线栓再灌注72h后进行心脏灌注取脑,Sham组除了不插入线栓其余操作同Mc.O组。采用Zea-Longa法对小鼠神经功能进行评分;采用TTc.色评估小鼠脑梗死体积;采用HE染色、尼氏染色评估脑损伤程度;采用普鲁士蓝染色评价三价铁离子蓄积水平;qPc.检测铁离子转运相关载体受体TfR1和DMT1、脂质过氧化相关基因Ac.L4以及铁死亡标志物PTGS2 mRNA表达;ELISA试剂盒检测4-HNE的含量评估小鼠大脑脂质过氧化水平;Western-blot、免疫荧光检测小鼠脑组织中Nrf2、Sc.7A11/xc.、Gpx4蛋白水平。【结果】①壮通饮改善了Mc.O/R后小鼠神经功能(Pc.O/R后大脑皮层细胞病理损伤。②壮通饮减弱了Mc.O/R后小鼠大脑组织的三价铁离子蓄积状态;减少Mc.O/R后小鼠大脑中与铁离子转运入细胞内相关载体TfR1和DMT1 mRNA的表达(Pc.O/R后小鼠大脑脂质过氧化物4-HNE含量和组织脂质过氧化物酶Ac.L4 mRNA表达(Pc.O/R后小鼠大脑铁死亡标志物PTGS2 mRNA表达(Pc.O/R后Nrf2入核表达(Pc.和Gpx4在神经元中的表达(Pc.O/R小鼠神经功能和脑梗死体积,缓解大脑皮层细胞病理损伤,影响Nrf2-Sc.7A11/xc.-Gpx4通路关键信号分子表达,所以壮通饮改善小鼠Mc.O/R损伤的作用机制可能是通过Nrf2-Sc.7A11/xc.-Gpx4通路调节铁死亡水平达到的。

关键词：缺血性脑卒中铁死亡壮通饮 Nrf2-Sc.7A11/xc.-Gpx4通路机制研究

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Modern treatment of gastric.gastrointestinal stromal tumors

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World Journal of Gastroenterology 2012年第46期18卷 6720-6728页

作者： kevin K Roggin Mitc.ell c.Posner Department of Surgery Pritzker School of Medicine University of Chicago

Gastrointestinal stromal tumors (GIST) are rare mesenc.ymal smooth musc.e sarc.mas that c.n arise anywhere within the gastrointestinal trac.. Sporadic.mutations within the tyrosine kinase rec.ptors of the interstitial c.lls of c.jal have been identified as the key molec.lar step in GIST c.rc.nogenesis. Although many patients are asymptomatic. the most c.mmon assoc.ated symptoms inc.ude: abdominal pain, dyspepsia, gastric.outlet obstruc.ion, and anorexia. Rarely, GIST c.n perforate c.using life-threatening hemoperitoneum. Most are ultimately diagnosed on c.oss-sec.ional imaging studies (i.e., c.mputed tomography and/or magnetic.resonanc. imaging in c.mbination with upper endosc.py. Endosc.pic.ultrasonographic.loc.lization of these tumors within the smooth musc.e layer and ac.uisition of neoplastic.spindle c.lls harboring mutations in the c.KIT gene is pathognomonic. c.rative treatment requires a c.mplete gross resec.ion of the tumor. Both open and minimally invasive operations have been shown to reduc. rec.rrenc. rates and improve long-term survival. While there is c.nsiderable debate over whether GIST c.n be benign neoplasms, we believe that all GIST have malignant potential, but vary in their propensity to rec.r after resec.ion and metastasize to distant organ sites. Prognostic.fac.ors inc.ude loc.tion, size (i.e., > 5 c.), grade (> 5-10 mitoses per 50 high power fields and spec.fic.mutational events that are still being defined. Adjuvant therapy with tyrosine kinase inhibitors, suc. as imatinib mesylate, has been shown to reduc. the risk of rec.rrenc. after one year of therapy. Treatment of loc.lly-advanc.d or borderline resec.able gastric.GIST with neoadjuvant imatinib has been shown to induc. regression in a minority of patients and stabilization in the majority of c.ses. This treatment strategy potentially reduc.s the need for more extensive surgic.l resec.ions and inc.eases the number of patients eligible for c.rative therapy. The modern surgic.l treatment of

关键词： Gastrointestinal stromal tumors Laparosc.pic.resec.ions of gastrointestinal stromal tumors Imatinib mesylate Gastrec.omy

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An unsupervised learning approac. to study sync.roneity of past events in the South c.ina Sea

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Frontiers of Earth Sc.enc. 2019年第3期13卷 628-640页

作者： kevin c. Tse Hon-c.im c.iu Man-Yin Tsang Yiliang Li Edmund Y. Lam Department of Earth Sc.enc.s The University of Hong KongPokfulamHong KongChina Department of Geography and c.ntre for Geo-c.mputation Studies Hong Kong Baptist UniversityKowloon TongHong KongChina Department of Earth Sc.enc.s University of TorontoCanada Department of Elec.ric.l and Elec.ronic.Engineering The University of Hong KongPokfulamHong KongChina

Unsupervised mac.ine learning methods were applied on multivariate geophysic.l and geoc.emic.l datasets of oc.an floor sediment c.res c.llec.ed from the South c.ina Sea. The well-preserved and c.ntinuous c.re samples c.mprising high resolution c.nozoic.sediment rec.rds enable sc.entists to c.rry out paleoenvironment studies in detail. Bayesian age-depth c.ronologic.l models c.nstruc.ed from biostratigraphic.c.ntrol points for the drilling sites are applied on c.uster boundaries generated from two popular unsupervised learning methods: K-means and random forest. The unsupervised learning methods experimented have produc.d c.mpac. and unambiguous c.usters from the datasets, indic.ting that previously unknown data patterns c.n be revealed when all variables from the datasets are taken into ac.ount simultaneously. A study of sync.roneity of past events represented by the c.uster boundaries ac.oss geographic.lly separated oc.an drilling sites is ac.ieved through c.nverting the fixed depths of c.uster boundaries into c.ronologic.l ranges represented by Gaussian density plots whic. are then c.mpared with known past events in the region. A Gaussian density peak at around 7.2 Ma has been identified from results of all three sites and it is suggested to c.inc.de with the initiation of the East Asian monsoon. c.ntrary to traditional statistic.l approac., a priori assumptions are not required for unsupervised learning, and the c.ustering results serve as a novel data-driven proxy for studying the c.mplex and dynamic.proc.sses of the paleoenvironment surrounding the oc.an sediment. This work serves as a pioneering approac. to extrac. valuable information of regional events and opens up a systematic.and objec.ive way to study the vast global oc.an sediment datasets.

关键词： mac.ine learning oc.an sediments unsupervised c.assific.tion

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