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Intra and extra pelvic multidisciplinary surgical approach of retroperitoneal sarcoma:Case series report

World Journal of Clinical Cases 2022年第27期10卷 9693-9702页

作者： Heekyoung Song Jung Hwan Ahn Yuyeon Jung Jae Yeon Woo Jimin Cha Yang-Guk Chung keun ho lee Department of Obstetrics and Gynecology Incheon St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Obstetrics and Gynecology Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Orthopaedic Surgery Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea

BACKGROUND Retroperitoneal sarcoma(RPS) is a rare malignancy arising from mesenchymal cells that most commonly presents as an abdominal mass and is associated with poor *** several studies have assessed the survival benefits of wide excision,few have reported detailed methods for achieving wide excision in patients with *** To describe our experience with multidisciplinary surgical resection of RPS using intra-and extra-pelvic *** Multidisciplinary surgery is an anatomical approach that combines intra-and extra-peritoneal access within the same surgery to achieve complete RPS *** retrospective review of the records of patients who underwent multidisciplinary surgery for RPS analyzed surgical and survival *** Eight patients underwent 10 intra-and extra-pelvic surgical resections,and their median mass size was 12.75 cm(range,6-45.5 cm).Using an intrapelvic approach,laparoscopy-assisted surgery was performed in four cases and laparotomy surgery in *** an extrapelvic approach,ilioinguinal and posterior approaches were used in four cases each,and the prone position and midline skin incision were shared in *** patients’ RPS masses were removed completely,and four achieved R0 resection through intra-and extra-pelvic *** median estimated blood loss was 2000 m L(range,300-20000 m L) and the median hospitalization was 12.6 d(range,9-69 d).Reoperation was needed in two patients(one for wound necrosis and the other for bowel perforation and wound necrosis).The median overall survival rate and median progression-free survival were 64.6 and 13.7 mo,*** RPS is therapeutically challenging because of its location and high risk of ***,intra-and extra-pelvic surgical approaches can improve the macroscopic security of the surgical margin.

关键词： Margins of excision Retroperitoneal neoplasms Sarcoma

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Bitmap lattice index in road networks

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Journal of Central South University 2014年第10期21卷 3856-3863页

作者： Doohee Song keun-ho lee Kwangjin Park Information Communication Engineering Wonkwang University Division of Information Communication Engineering Baekseok University

A novel technique called the bitmap lattice index(BLI) is proposed, which combines the advantages of a wireless broadcasting environment with a road network. Existing road networks are based on the on-demand method: a server's workload increases as the query request increases when a server sends a client information. To solve this problem, we propose the BLI. The BLI denotes an object and a node as 0 and 1 in the Hilbert curve(HC) map. The BLI can identify the position of a node and an object through bit information; it can also reduce the broadcasting frequency of a server by reducing the size of the index, thereby decreasing the access latency and query processing times. Moreover, the BLI is highly effective for data filtering, as it can identify the positions of both an object and a node. In a road network, if filtering is done via the Euclidean distance, it may result in an error. To prevent this, we add another validation procedure. The experiment is conducted by applying the BLI to kNN query, and the technique is assessed by a performance evaluation experiment.

关键词：位图索引网格道路网络信息查询欧几里德距离无线广播等待时间数据过滤

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Long cycle-life aqueous Zn battery enabled by facile carbon nanotube coating on Cu current collector

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Carbon Energy 2024年第6期6卷 151-164页

作者： Beom-keun Cho Sung-ho Huh So Hee Kim Seungho Yu Jong-Seong Bae Jung-keun Yoo Seung-ho Yu Department of Chemical and Biological Engineering Korea UniversitySeoulRepublic of Korea Advanced Analysis Center Korea Institute of Science and Technology(KIST)SeoulRepublic of Korea Energy Storage Research Center Korea Institute of Science and Technology(KIST)SeoulRepublic of Korea KIST School Division of Energy and Environment TechnologyKorea University of Science and TechnologySeoulRepublic of Korea Busan Center Korea Basic Science Institute(KBSI)BusanRepublic of Korea Carbon Composites Department Composites Research DivisionKorea Institute of Materials Science(KIMS)ChangwonRepublic of Korea

As an alternative to Li-ion batteries,aqueous Zn batteries have gained attention due to the abundance of Zn metal,low reduction potential(-0.76 V *** hydrogen electrode),and high theoretical capacity(820 mAh g-1)of multivalent Zn2+***,the growth of Zn dendrites and the formation of irreversible surface reaction byproducts pose challenges for ensuring a long battery lifespan and ***,the Cu foil coated with a single-walled carbon nanotube(SWCNT)layer using a facile doctor blade casting method is *** SWCNT-coated Cu foil demonstrates a significantly longer battery lifespan compared to the bare Cu in the half-cell *** operando optical microscopy imaging,we are able to provide intuitive evidence that Zn deposition occurs between the carbon nanotube(CNT)coating and Cu substrate,in agreement with the computational ***,with various imaging techniques,the flat morphology and homogeneous distribution of Zn beneath the SWCNT layer are *** addition,the full-cell using CNT-coated Cu exhibits a long cycle life compared to the control group,thereby demonstrating improved electrochemical performance with limited Zn for the cycling process.

关键词： aqueous Zn battery carbon nanotube operando imaging surface coating

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Apolipoprotein A-I binding protein-mediated neuroprotection in glaucomatous neuroinflammation and neurodegeneration

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Neural Regeneration Research 2025年第5期20卷 1414-1415页

作者： Sinwoo Hwang Seunghwan Choi Soo-ho Choi keun-Young Kim Yury I.Miller Won-Kyu Ju Hamilton Glaucoma Center and Shiley Eye Institute The Viterbi Family Department of OphthalmologyUniversity of California San DiegoLa JollaCAUSA Department of Medicine University of California San DiegoLa JollaCAUSA National Center for Microscopy and Imaging Research Department of NeurosciencesUniversity of California San DiegoLa JollaCAUSA

Glaucoma is a multifactorial eye disorder that can cause vision loss and irreversible blindness,affecting individ uals aged 40 to 80 yea rs *** to the aging population,it is expected that the number of people affected by glaucoma will surpass 111 million by 2040 as the disease becomes more *** primarily contributes to optic nerve axon loss and the progressive degeneration of retinal ganglion cells (RGCs),subsequently leading to vision impairment.

关键词： irreversible pass primarily

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Degradable and Tunable Keratin-fibrinogen Hydrogel as Controlled Release System for Skin Tissue Regeneration

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Journal of Bionic Engineering 2023年第3期20卷 1049-1059页

作者： Sung Jun Min Jae Seo lee Haram Nah ho-Jin Moon Sang Jin lee Hyeon Jeong Kang Yu-Shik Hwang Il keun Kwon Dong Nyoung Heo Department of Dentistry Graduate SchoolKyung Hee University26 Kyungheedae-RoDongdaemun-GuSeoul02447Republic of Korea Biofriends Inc 26 Kyungheedae-RoDongdaemun-GuSeoul02447Republic of Korea Department of Dental Materials School of DentistryKyung Hee University26 Kyungheedae-RoDongdaemun-GuSeoul02447Republic of Korea Department of Maxillofacial Biomedical Engineering and Institute of Oral Biology School of DentistryKyung Hee UniversitySeoul02447Korea Kyung Hee University Medical Science Research Institute Kyung Hee University23 Kyungheedae-RoDongdaemun-GuSeoul02447Republic of Korea

Biodegradable hydrogels are promising biomaterials for use in controlled-release systems for skin tissue regeneration. Controlled delivery systems constitute an important aspect of tissue engineering because they can modulate various physiological responses, including early immune response, tissue remodeling, and cell proliferation and maturation in the wound-healing process. Hydrogels composed of various biomaterials have been developed to overcome the limitations of conventional drug- or protein-delivery systems, such as limited targeting ability, low stability, and the induction of drug resistance. Hydrogels based on keratin, a natural polymer extracted from human hair, can provide adequate cell support and control homeostasis. Consequently, they can be applied for skin tissue engineering. In this study, we prepared degradable, tunable, and biocompatible hydrogels for controllable protein delivery. We synthesized keratin-fibrinogen (KER-FBG) by the chemical coupling reaction and prepared hydrogels through polymerization with thrombin. The structures and morphologies of the KER-FBG hydrogels were confirmed. Furthermore, the mechanical properties, swelling ratio, degradation, release behavior, and biocompatibility were investigated. The KER-FBG hydrogels presented promising biological performance, indicating that the material is suitable as a controlled protein delivery carrier.

关键词： Keratin Fibrinogen Hydrogel Drug delivery Degradable

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Sex-based differences in histology,staging,and prognosis among 2983 gastric cancer surgery patients

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World Journal of Gastroenterology 2022年第9期28卷 933-947页

作者： Yonghoon Choi Nayoung Kim Ki Wook Kim Hyeong ho Jo Jaehyung Park Hyuk Yoon Cheol Min Shin Young Soo Park Dong ho lee Hyeon Jeong Oh Hye Seung lee Young Suk Park Sang-hoon Ahn Yun-Suhk Suh Do Joong Park Hyung-ho Kim Ji-Won Kim Jin Won Kim keun-Wook lee Won Chang Ji hoonPark Yoon Jin lee Kyoung ho lee Young hoon Kim Department ofInternal Medicine Seoul National University Bundang HospitalSeongnam 13620South Korea Nayoung Department of Internal Medicine Seoul National University College of MedicineSeoul 03080South Korea Department of Pathology Seoul National University Bundang HospitalSeongnam 13620South Korea Department of Pathology Seoul National University College of MedicineSeoul 03080South Korea Department of Surgery Seoul National University Bundang HospitalSeongnam 13620South Korea Department of Surgery Seoul National University College of MedicineSeoul 03080South Korea Department of Radiology Seoul National University Bundang HospitalSeongnam 13620South Korea Department of Radiology Seoul National University College of MedicineSeoul 03080South Korea

BACKGROUND Few studies have been conducted on sex differences in the incidence, pathophysiology, and prognosis of gastric cancer(GC).AIM To analyze the differences in GC characteristics according to sex in patients who underwent surgical treatment for *** A total of 2983 patients diagnosed with gastric adenocarcinoma who received surgical treatment at the Seoul National University Bundang hospital between 2003 and 2017 were *** clinicopathological characteristics, histologic type of GC, overall and GC-specific survival rates, and associated risk factors were *** Among the 2983 patients, 2005(67.2%) and 978(32.8%) were males and females, *** average age of the female group(59.36 years) was significantly younger than that of the male group(61.66 years;P however, this difference disappeared for GC-specific survival(P = 0.168), except for the poor GC-specific survival rate in advanced-stage cancer(stage Ⅲ or above) in females(P = 0.045).The risk factors for GC-related mortality were older age, upper location of GC, and diffuse-or mixed-type *** terms of comorbidities, more males died from diseases other than GC, including other malignancies such as lung cancer, hepatocellular carcinoma, and pancreatic cancer, and respiratory diseases such as interstitial lung disease and chronic obstructive pulmonary disease, while there were relatively more cardiovascular or cerebrovascular deaths in *** Sex-based differences in GC were

关键词： Gastric cancer Histology Prognosis Sex difference Survival

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Sound transducer calibration of ambulatory audiometric system utilizing delta learning rule

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Journal of Central South University 2011年第6期18卷 2009-2014页

作者： KIM Kyeong-seop SHIN Seung-won YOON Tae-ho lee Sang-min lee Insung RYU keun ho School of Biomedical Engineering Konkuk University Xiu Solution Co. Ltd. Department of Electronic Engineering Inha University Department of Radio Communication Engineering Chungbuk National University Database/Bioinformatics Lab Chungbuk National University

An efficient calibration algorithm for an ambulatory audiometric test system is proposed. This system utilizes a personal digital assistant (PDA) device to generate the correct sound pressure level (SPL) from an audiometric transducer such as an earphone. The calibrated sound intensities for an audio-logical examination can be obtained in terms of the sound pressure levels of pure-tonal sinusoidal signals in eight-banded frequency ranges (250, 500, 1 000, 2 000, 3 000, 4 000, 6 000 and 8 000 Hz), and with mapping of the input sound pressure levels by the weight coefficients that are tuned by the delta learning rule. With this scheme, the sound intensities, which evoke eight-banded sound pressure levels by 5 dB steps from a minimum of 25 dB to a maximum of 80 dB, can be generated without volume displacement. Consequently, these sound intensities can be utilized to accurately determine the hearing threshold of a subject in the ambulatory audiometric testing environment.

关键词：传感器校准声音强度规则系统三角洲门诊听力个人数字助理声压级

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Role of adjuvant chemoradiotherapy and chemotherapy in patients with resected gallbladder carcinoma: a multiinstitutional analysis (KROG 19-04)

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Cancer Biology & Medicine 2022年第6期19卷 931-944页

作者： Sung Uk lee Jinsil Seong Tae Hyun Kim Jung ho Im Woo Chul Kim Kyubo Kim Hae Jin Park Tae Gyu Kim Youngkyong Kim Bae Kwon Jeong Jin Hee Kim Byoung Hyuck Kim Taek-keun Nam Center for Proton Therapy and Center for Liver and Pancreatobiliary Cancer National Cancer CenterGoyang 10408Korea Department of Radiation Oncology Yonsei Cancer CenterYonsei University College of MedicineSeoul 03722Korea Department of Radiation Oncology CHA Bundang Medical CenterCHA University School of MedicineSeongnam 13497Korea Department of Radiation Oncology Inha University HospitalInha University School of MedicineIncheon 22332Korea Department of Radiation Oncology Ewha Womans University Mokdong HospitalEwha Womans University College of MedicineSeoul 07985Korea Department of Radiation Oncology Hanyang University Medical CenterHanyang University College of MedicineSeoul 04763Korea Department of Radiation Oncology Samsung Changwon HospitalSungkyunkwan University School of MedicineChangwon 51353Korea Department of Radiation Oncology Kyung Hee University HospitalKyung Hee University College of MedicineSeoul 02447Korea Department of Radiation Oncology Gyeongsang National University HospitalGyeongsang National University College of MedicineJinju 52727Korea Department of Radiation Oncology Dongsan Medical CenterKeimyung University School of MedicineDaegu 41931Korea Department of Radiation Oncology Seoul Metropolitan Government Seoul National University Boramae Medical CenterSeoul 07061Korea Department of Radiation Oncology Chonnam National University Hwasun HospitalChonnam National University College of MedicineHwasun 58128Korea

Objective:The effectiveness of adjuvant treatments for resected gallbladder carcinoma(GBC)has remained unclear due to lack of randomized controlled trials;thus,the aim of present study was to evaluate the role of adjuvant treatments,including chemoradiotherapy(CRT)and/or chemotherapy(CTx),in patients with resected ***:A total of 733 GBC patients who received curative-intent surgical resection were identified in a multi-institutional *** 733 patients,372(50.8%)did not receive adjuvant treatment,whereas 215(29.3%)and 146(19.9%)received adjuvant CTx and CRT,*** locoregional recurrence-free survival(LRFS),recurrence-free survival(RFS),and overall survival(OS)of the adjuvant treatment groups were compared according to tumor stage(stage II *** III–IV).Results:In stage II disease(n=381),the 5-year LRFS,RFS,and OS were not significantly different among the no-adjuvant therapy,CTx,and CRT groups,and positive resection margin,presence of perineural invasion,and Nx classification were consistently associated with worse LRFS,RFS,and OS in the multivariate analysis(P<0.05).For stage III–IV(n=352),the CRT group had significantly higher 5-year LRFS,RFS,and OS than the no-adjuvant therapy and CTx groups(67.8%,45.2%,and 56.9%;37.9%,28.8%,and 35.4%;and 45.0%,30.0%,and 45.7%,respectively)(P<0.05).Conclusions:CRT has value as adjuvant treatment for resected GBC with stage III–IV *** study is needed for stage II disease with high-risk features.

关键词： Gallbladder cancer adjuvant treatment chemoradiotherapy locoregional recurrence-free survival overall survival

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Authentication masking code against DoS of T-MAC protocol

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中南大学学报：英文版 2013年第7期20卷 1889-1895页

作者： SON Young-ho hoNG Jin-keun BAE keun-sung Attached Institute of ETRI Division of Information & Communication Baekseok University School of Electrical Engineering & Computer Science Kyungpook National University

Security vulnerability of denial of service (DoS) in time out-medium access control (T-MAC) protocol was discussed and analysis of power consumption at each stage of T-MAC protocol was carried out. For power efficient authentication scheme which can provide reliability, efficiency, and security for a general T-MAC communication, a novel synchronization and authentication scheme using authentication masking code was proposed. Authentication data were repeated and masked by PN sequence. The simulation results show that the proposed approach can provide synchronization and authentication simultaneously for nodes in wireless sensor network (WSN). 63 bits AMC code gives above 99.97% synchronization detection and 93.98% authentication data detection probability in BER 0.031 7.

关键词： MAC协议身份验证 C代码 DOS 掩蔽无线传感器网络节能认证介质访问控制

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Characteristic evaluation of Al_2O_3/CNTs hybrid materials for micro-electrical discharge machining

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Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 28-32页

作者： Hyun-Seok TAK Chang-Seung HA ho-Jun lee Hyung-Woo lee Young-keun JEONG Myung-Chang KANG National Core Research Center for Hybrid Materials Solution Pusan National University Department of Electrical Engineering Pusan National University

The characteristic evaluation of aluminum oxide (Al2O3)/carbon nanotubes (CNTs) hybrid composites for micro-electrical discharge machining (EDM) was described. Alumina matrix composites reinforced with CNTs were fabricated by a catalytic chemical vapor deposition method. Al2O3 composites with different CNT concentrations were synthesized. The electrical characteristic of Al2O3/CNTs composites was examined. These composites were machined by the EDM process according to the various EDM parameters, and the characteristics of machining were analyzed using field emission scanning electron microscope (FESEM). The electrical conductivity has a increasing tendency as the CNTs content is increased and has a critical point at 5% Al2O3 (volume fraction). In the machining accuracy, many tangles of CNT in Al2O3/CNTs composites cause violent spark. Thus, it causes the poor dimensional accuracy and circularity. The results show that conductivity of the materials and homogeneous distribution of CNTs in the matrix are important factors for micro-EDM of Al2O3/CNTs hybrid composites.

关键词：加工特性混合材料微细电火花加工混杂复合材料场发射扫描电子显微镜微放电催化化学气相沉积法碳纳米管

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