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Determinants of Malignant Transformation in Fibrocystic Disease of Breast

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Advances in Breast Cancer Research 2014年第2期3卷 54-58页

作者： ketan vagholkar Department of Surgery Dr. D. Y. Patil Medical College Navi Mumbai India

Background: Fibrocystic disease of the breast in one of the commonest diseases in women above 30 years of age. The assumption of it being innocuous and benign is questionable with increased incidence of malignancies developing in these women. Introduction: Understanding the pathophysiology of fibrocystic disease is essential for identifying determinants of malignant change. Case Report: A case of carcinoma of breast developing in a longstanding and recurrent fibrocystic disease is reported. Discussion: The pathological changes including the influence of hormones on the natural history of the disease arediscussed to identify the determinants of malignant transformation. Conclusion: Breast cyst fluid, patterns of cellular lining of the cysts, multiplicity, recurrence and patterns of cellular morphology are important determinants of malignant change.

关键词： Fibrocystic Disease Breast Carcinoma

Strangulated Femoral Hernia: A Challenging Surgical Vignette —Case Report and Review of Literature

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International Journal of Clinical Medicine 2014年第2期5卷 72-75页

作者： ketan vagholkar Department of Surgery Dr. D.Y. Patil Medical College Navi Mumbai India

External hernia is one of the commonest causes of intestinal obstruction. Femoral hernia is a relatively uncommon hernia. It has a very high complication rate due to delayed diagnosis caused by deceptive symptomatology and subtle signs. CT scan enables a prompt diagnosis. Rigorous resuscitation followed by prompt surgical intervention is the mainstay of treatment. A case of a strangulated femoral hernia in a patient with complicated co morbid medical disorders is presented to highlight the pitfalls in initial clinical assessment.

关键词： Strangulated Femoral Hernia Diagnosis Surgical Treatment

Lipomas of the Colon: A Surgical Challenge

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International Journal of Clinical Medicine 2014年第6期5卷 309-313页

作者： ketan vagholkar Mahendra Bendre Department of Surgery Dr. D. Y. Patil Medical College Navi Mumbai India

Lipomas of the colon are rare benign tumors second only to adenomas in their incidence. They are devoid of malignant potential. They usually become manifest by way of complications ranging from bleeding to acute intestinal obstruction. Radiological investigations may help to confirm the diagnosis in a significant number of non-emergent situations. However, confirmation of diagnosis is invariably done at the time of therapeutic intervention. A proper choice of therapeutic option between endoscopic or open surgical intervention needs to be made for a good outcome.

关键词： Lipoma Colon Complications Treatment Endoscopic Surgical

Coexistence of Carcinoma and Tuberculosis in the Breast: A Rarity

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Case Reports in Clinical Medicine 2015年第1期4卷 14-18页

作者： ketan vagholkar Abhijit Budhkar Indumati Gopinathan Dr. D. Y. Patil Medical College Navi Mumbai India Clinicopathological Laboratory Mumbai India

Background: Malignancy of the breast is one of the commonest lesions of the breast. Amongst the infective lesions tuberculosis has now become a common occurrence especially in the developing world. However, co-existence of the two in the same breast is extremely rare. Introduction: Since both of these lesions have a different natural history, co-existence of tuberculosis and malignancy poses a diagnostic dilemma to both the surgeon and the pathologist. Awareness of the co-existence of the two lesions in the same patient is pivotal for early diagnosis and planning the management. Case Report: In view of its rarity, a case of coexistence of the two diseases in the same beast is reported in order to create an awareness of their co-existence. Discussion: The diagnostic implications and management are discussed. Conclusion: Awareness of the co-existence of these divergent pathological conditions is essential for early diagnosis and planning of an accurate treatment protocol.

关键词： Tuberculosis Carcinoma Breast Coexistence