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Because of the toxicity of lead,searching for a lead-free halide perovskite semiconducting material with comparable optical and electronic properties is of great ***-earth based halide perovskite represents a promising class of materials for this *** demonstrate the solution-phase synthesis of single-crystalline CsEuCl nanocrystals with a uniform size distribution centered around 15 *** CsEuCl nanocrystals have photoluminescence emission centered at 435 nm, with a full width at half-maximum of 19 ***,CsEuClnanocrystals can be embedded in a polymer matrix that provides enhanced stability under continuous laser ***-free rare-earth cesium europium halide perovskite nanocrystals represent a promising candidate to replace lead halide perovskites.

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蓝牙Mesh:构想全新的应用领域

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电子产品世界 2019年第2期26卷 15-17页

作者： kerstin Wagner 儒卓力

Mesh技术允许多个蓝牙设备连接在一起从而形成一个大型网络,以节能和安全的方式实现远距离桥接。通过在安全性、可靠性和可扩展性方面满足行业标准,蓝牙Mesh技术可以实现全新的应用场景。

关键词： Mesh 蓝牙应用大型网络设备连接行业标准可扩展性安全性

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The Influence of Naturalness, Attractiveness and Intensity on Facial Emotion Recognition

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Psychology Research 2012年第3期2卷 166-176页

作者： kerstin Limbrecht Stefanie Rukavina Andreas scheck Steffen Walter Holger Hoffman Harald C. Traue University of Ulm Ulm Germany

Understanding the determinants facial emotion recognition is still one of the main topics in emotion research. Mimic expressions are not only a representation of feelings caused by emotions, but are also an important communication channel in social interaction. Research of the last 20 years could show that emotion recognition abilities differ within and between individuals. Moreover, every basic emotion seems to be processed differently in the human brain. Underlying processes are still not clear. In this study, the common practice of presenting pictures of faces showing basic emotions to participants was used in a more methodological sense. Possible determining factors in facial emotion recognition, like naturalness and intensity of the expressed emotion and the attractiveness of the photographed person, were analyzed.

关键词：面部表情识别吸引力自然强度情感表达社会交往识别能力情绪

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作为课程原则的儿童哲学——教育理论的根据与经验基础

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陕西学前师范学院学报 2018年第10期34卷 11-17页

作者： kerstin Michalik 杨妍璐德国汉堡大学浙江大学哲学系浙江杭州310027

本文系德国汉堡大学教授凯斯汀·米夏利克(kerstin Michalik)在德国教育学杂志《教育学全球展望》(《Pdagogische Rundschau》)2013年第6期所发表的论文。凯斯汀从理论与实证的双重维度阐述了作为课程原则的儿童哲学对于学校教育的必... 详细信息

本文系德国汉堡大学教授凯斯汀·米夏利克(kerstin Michalik)在德国教育学杂志《教育学全球展望》(《Pdagogische Rundschau》)2013年第6期所发表的论文。凯斯汀从理论与实证的双重维度阐述了作为课程原则的儿童哲学对于学校教育的必要性和重要性。哲学探究在跨学科的运用中有其教育理论根据与经验基础,并在全世界的跟踪研究中表明,哲学探究的方法不仅将促进学生对于学科对象的学习,也有助于学生在社会交往中提升自己的各项能力。

关键词：哲学探究跨课程教学方法

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The next-generation sphingosine-1 receptor modulator BAF312(siponimod) improves cortical network functionality in focal autoimmune encephalomyelitis

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Neural Regeneration Research 2019年第11期14卷 1950-1960页

作者： Petra Hundehege Manuela Cerina Susann Eichler Christian Thomas Alexander M. Herrmann kerstin Goel Thomas Müntefering Juncal Fernandez-Orth Stefanie Bock Venu Narayanan Thomas Budde Erwin-Josef Speckmann Heinz Wiendl Anna schubart Tobias Ruck Sven G. Meuth Department of Neurology with Institute of Translational Neurology Westfalische Wilhelms-UniversitatMunsterGermany Institute of Physiology I Westfalische Wilhelms-UniversitatMunsterGermany Novartis Institutes of Biomedical Research BaselSwitzerland

Autoimmune diseases of the central nervous system(CNS) like multiple sclerosis(MS) are characterized by inflammation and demyelinated lesions in white and grey matter regions. While inflammation is present at all stages of MS, it is more pronounced in the relapsing forms of the disease, whereas progressive MS(PMS) shows significant neuroaxonal damage and grey and white matter atrophy. Hence, disease-modifying treatments beneficial in patients with relapsing MS have limited success in PMS. BAF312(siponimod) is a novel sphingosine-1-phosphate receptor modulator shown to delay progression in PMS. Besides reducing inflammation by sequestering lymphocytes in lymphoid tissues, BAF312 crosses the blood-brain barrier and binds its receptors on neurons, astrocytes and oligodendrocytes. To evaluate potential direct neuroprotective effects, BAF312 was systemically or locally administered in the CNS of experimental autoimmune encephalomyelitis mice with distinct grey-and white-matter lesions(focal experimental autoimmune encephalomyelitis using an osmotic mini-pump). Ex-vivo flow cytometry revealed that systemic but not local BAF312 administration lowered immune cell infiltration in animals with both grey and white matter lesions. Ex-vivo voltage-sensitive dye imaging of acute brain slices revealed an altered spatio-temporal pattern of activation in the lesioned cortex compared to controls in response to electrical stimulation of incoming white-matter fiber tracts. Here, BAF312 administration showed partial restore of cortical neuronal circuit function. The data suggest that BAF312 exerts a neuroprotective effect after crossing the blood-brain barrier independently of peripheral effects on immune cells. Experiments were carried out in accordance with German and EU animal protection law and approved by local authorities(Landesamt für Natur, Umwelt und Verbraucherschutz Nordrhein-Westfalen;87-51.04.2010.A331) on December 28, 2010.

关键词： multiple sclerosis focal experimental autoimmune encephalomyelitis cortical grey matter white matter BAF312 neuroaxonal damage neuroprotection

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ChIP-Hub: an integrative platform for exploring plant regulome

ChIP-Hub: an integrative platform for exploring plant regulo...

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第十九届中国作物学会学术年会

作者： Liang-Yu Fu Zhigui Wu kerstin Kaufmann 陈迪俊 State Key Laboratory of Pharmaceutical Biotechnology School of Life Sciences Nanjing University Department for Plant Cell and Molecular Biology Institute for Biology Humboldt-Universit?t zu Berlin

ChIP-seq and complementary assays are powerful methods to measure protein-DNA binding events and chemical modifications of histone proteins at genome-wide level. In recent years, an explosion of regulome data are being generated in plants. However, reuse and comparison of data generated by different laboratories is not straightforward, hampering data integration to generate novel hypotheses for further investigation. Here, we adapt the standard provided by the ENCODE consortium to set up computational pipelines and systematically reanalyze public ChIP-seq(as well as DAP-seq) data in plants. We further present an integrative web-based platform(ChIP-Hub) for exploring the comprehensive reanalysis of more than 8000 ChIP-seq datasets in 42 plant species. The resources are bundled in a well-accessible database that also allows visualization and meta-analyses. This resource will allow experimental biologists from various fields to comprehensively use all available epigenomic information to get novel insights into their specific questions. ChIP-Hub is available at http://***/.

关键词： plants regulome ChIP-seq ChIP-Hub

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