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Promoting Health Behavior Change in Canada: A Quality Improvement Project Integrating Prevention and Wellness in Frontline Care

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Open Journal of Psychiatry 2021年第3期11卷 125-137页

作者： Kiran Rabheru David Conn Daria Parsons Ariane S. Massie Julie Mitchell Michael Vallis Claire Checkland keri-leigh cassidy Department of Psychiatry University of Ottawa Ottawa Canada Canadian Coalition for Seniors’ Mental Health Toronto Canada Department of Psychiatry University of Toronto Toronto Canada Department of Psychology Dalhousie University Halifax Canada Department of Psychiatry Dalhousie University Halifax Canada

Background: The critical need for Health Behaviour Change (HBC) for preventative care has been highlighted by the COVID-19 pandemic. This quality improvement project assessed the effectiveness and acceptability of Fountain of Health HBC tools as a minimal intervention for primary and secondary prevention among Canadian clinicians and their patients. Methods: Clinicians received HBC education and tools (paper tools and app-based) to assist their patients in setting a S.M.A.R.T (Specific, Measurable, Action-oriented, Realistic, Time-limited) goal at baseline and assessed four weeks later. Primary outcome measures were: 1) patient self-report of success at goal attainment;2) patient self-reported evaluation of change in well-being and health attitudes;and 3) clinician experience and engagement. Results: A total of 2184 clinicians received HBC education. Of these, 759 clinicians registered to participate in the project. 961 patients set S.M.A.R.T. HBC goals using either the paper tools (PT) or the app format. Patient data revealed nearly all patients (89% of PT users and 90% of app users) at least partially succeeded in attaining their goal at a four-week follow-up. Most patients (85% of PT and 80% of app users) also reported improvement in their well-being. A significant difference in health beliefs and attitudes was found in both PT (p Conclusions: HBC is challenging. Educating and providing clinicians with HBC tools as a minimal intervention was found to be a successful health prevention strategy to improve patient well-being and health attitudes, and achieve S.M.A.R.T. goals. Results show HBC tools, education, and support for clinicians are both acceptable and effective for HBC in frontline care. These findings are relevant and timely given greater reliance on virtual care in the wake of the COVID-19 pandemic. Further research with rigorous methodology is needed t

关键词： Behaviour Sciences Mental Health Medical Education Primary and Secondary Prevention Health Behavior Change Risk Reduction Tools for Health and Wellness Positive Psychiatry

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Regioselective synthesis of α-D-glucopyranosiduronic acid derivatives and biological test against bacterial Staphylococcus aureus and Salmonella agona

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Science China Chemistry 2010年第4期53卷 877-883页

作者： cassidy Seamas Food Science and Environmental Health Department Dublin Institute of Technology Dublin 1 Ireland

α-D-Glucopyranosiduronides were stereoselectively synthesized from D-glucopyranosiduronic acid via the intermediate 1,6-lactone. Fatty acid esters were regioselectively introduced at the 2-O-position of α-D-glucopyranosiduronides using dibutyltin dimethoxide as the stannylating agent. Antibacterial tests show that methyl 2-O-lauroyl-O-D-glucopyranosiduronic acid and azido 2-O-lauroyl-O-D-glucopyranosid-uronic acid are effective inhibitors against Staphylococcus aureus.

关键词： dibutyltin dimethoxide stereoselectivity regioselectivity antibacterial

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Quark-Novae Ia in the Hubble diagram: implications for dark energy

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Research in Astronomy and Astrophysics 2014年第5期14卷 497-519页

作者： Rachid Ouyed Nico Koning Denis Leahy Jan E.Staff Daniel T.cassidy Department of Physics and Astronomy University of Calgary 2500 University Drive NWCalgary Alberta T2N 1N4 Canada Department of Physics and Astronomy Macquarie University NSW 2109 Australia Department of Engineering Physics McMaster University Hamilton Ontario L8S 4L7 Canada

The accelerated expansion of the Universe was proposed through the use of Type-Ia supernovae （SNe） as standard candles. The standardization depends on an empirical correlation between the stretch/color and peak luminosity of the light curves. The use of Type-Ia SNe as standard candles rests on the assumption that their properties （and this correlation） do not vary with redshift. We consider the possibility that the majority of Type-Ia SNe are in fact caused by a Quark-Nova detonation in a tight neutron-star-CO-white-dwarf binary system, which forms a Quark-Nova Ia （QN-Ia）. The spin-down energy injected by the Quark-Nova remnant （the quark star） contributes to the post-peak light curve and neatly explains the observed correlation between peak luminosity and light curve shape. We demonstrate that the parameters describing QN-Ia are NOT constant in redshift. Simulated QN-Ia light curves provide a test of the stretch/color correlation by comparing the true distance modulus with that determined using SN light curve fitters. We determine a correction between the true and fitted distance moduli, which when applied to Type-Ia SNe in the Hubble diagram recovers the ΩM = 1 cosmology. We conclude that Type-Ia SNe observations do not necessitate the need for an accelerating expansion of the Universe （if the observed SNe Ia are dominated by QNe Ia） and by association the need for dark energy.

关键词： dark energy -- cosmology observations -- supernovae general

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Assessment of pipeline stability in the Gulf of Mexico during hurricanes using dynamic analysis

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Theoretical & Applied Mechanics Letters 2015年第2期5卷 74-79页

作者： Yinghui Tian Bassem Youssef Mark J.cassidy Centre for Offshore Foundation Systems and ARC CoE for Geotechnical Science and Engineering University of Western Australia Atteris Level 3220 St Georges TerracePerthWA6000Australia

Pipelines are the critical link between major offshore oil and gas developments and the mainland. Any inadequate on-bottom stability design could result in disruption and failure, having a devastating impact on the economy and environment. Predicting the stability behavior of offshore pipelines in hurricanes is therefore vital to the assessment of both new design and existing assets. The Gulf of Mexico has a very dense network of pipeline systems constructed on the seabed. During the last two decades, the Gulf of Mexico has experienced a series of strong hurricanes, which have destroyed, disrupted and destabilized many pipelines. This paper first reviews some of these engineering cases. Following that, three case studies are retrospectively simulated using an in-house developed program. The study utilizes the offshore pipeline and hurricane details to conduct a Dynamic Lateral Stability analysis, with the results providing evidence as to the accuracy of the modeling techniques developed.

关键词： Pipeline On-bottom stability Dynamic lateral stability analysis Force-resultant model Hydrodynamic load

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锡类络合物在糖衍生物合成中的区域选择性

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化学通报 2010年第4期73卷 308-313页

作者：楼鑫侯金松 Seamas cassidy 滁州学院化学与生命科学系安徽滁州239000 Food Science and Environmental Health Dublin Institute of Technology

锡类化合物在选择性糖衍生物合成中应用得相当广泛,亚甲锡烷基方法在吡喃糖衍生物合成中体现了高区域选择性。本文从三丁基锡醚和二丁基锡缩醛与糖类形成的络合物结构出发,揭示了其区域选择性的根本原因在于通过聚合作用使得处于不同位... 详细信息

锡类化合物在选择性糖衍生物合成中应用得相当广泛,亚甲锡烷基方法在吡喃糖衍生物合成中体现了高区域选择性。本文从三丁基锡醚和二丁基锡缩醛与糖类形成的络合物结构出发,揭示了其区域选择性的根本原因在于通过聚合作用使得处于不同位置的羟基显示不同的电负性和亲核性;还讨论了吡喃糖类中不同类型的多元醇系统和锡络合后所表现的区域选择性。

关键词：糖二丁基氧化锡三丁基锡醚区域选择性

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The role of artificial intelligence technology in the care of diabetic foot ulcers: the past, the present, and the future

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World Journal of Diabetes 2022年第12期13卷 1131-1139页

作者： Joseph M Pappachan Bill cassidy Cornelius James Fernandez Vishnu Chandrabalan Moi Hoon Yap Department of Endocrinology&Metabolism Lancashire Teaching Hospitals NHS TrustPreston PR29HTUnited Kingdom Faculty of Science and Engineering Manchester Metropolitan UniversityManchester M156BHUnited Kingdom Department of Endocrinology&Metabolism Pilgrim HospitalBoston PE219QSUnited Kingdom Department of Data Science Lancashire Teaching Hospitals NHS TrustPreston PR29HTUnited Kingdom

Foot ulcers are common complications of diabetes mellitus and substantially increase the morbidity and mortality due to this *** care by regular monitoring of the progress of healing with clinical review of the ulcers,dressing changes,appropriate antibiotic therapy for infection and proper offloading of the ulcer are the cornerstones of the management of foot *** the progress of foot ulcers can be a challenge for the clinician and patient due to logistic issues such as regular attendance in the *** clinics are often busy and because of manpower issues,ulcer reviews can be delayed with detrimental effects on the healing as a result of a lack of appropriate and timely changes in *** photographs have been historically useful to assess the progress of diabetic foot ulcers over the past few *** phones with digital cameras have recently revolutionized the capture of foot ulcer *** can send ulcer photographs to diabetes care professionals electronically for remote monitoring,largely avoiding the logistics of patient transport to clinics with a reduction on clinic *** intelligence-based technologies have been developed in recent years to improve this remote monitoring of diabetic foot ulcers with the use of mobile *** is expected to make a huge impact on diabetic foot ulcer care with further research and development of more accurate and scientific technologies in *** clinical update review aims to compile evidence on this hot topic to empower clinicians with the latest developments in the field.

关键词： Diabetic foot ulcers Photographic monitoring Artificial intelligence technology Digital photography Mobile app COVID-19 pandemic

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The skeletal muscle fiber periphery:A nexus of mTOR-related anabolism

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Sports Medicine and Health Science 2023年第1期5卷 10-19页

作者： cassidy T.Tinline-Goodfellow Matthew J.Lees Nathan Hodson Faculty of Kinesiology and Physical Education University of TorontoCanada Institute of Sport Manchester Metropolitan UniversityManchesterUnited Kingdom Department of Sport and Exercise Sciences Manchester Metropolitan UniversityManchesterUnited Kingdom

Skeletal muscle anabolism is driven by numerous stimuli such as growth factors,nutrients(i.e.,amino acids,glucose),and mechanical *** stimuli are integrated by the mechanistic target of rapamycin(mTOR)complex 1(mTORC1)signal transduction *** recent years,work from our laboratory and elsewhere has sought to unravel the molecular mechanisms underpinning the mTOR-related activation of muscle protein synthesis(MPS),as well as the spatial regulation of these mechanisms within the skeletal muscle *** studies have suggested that the skeletal muscle fiber periphery is a region of central importance in anabolism(i.e.,growth/MPS).Indeed,the fiber periphery is replete with the substrates,molecular machinery,and translational apparatus necessary to facilitate *** review provides a summary of the mechanisms underpinning the mTOR-associated activation of MPS from cell,rodent,and human *** also presents an overview of the spatial regulation of mTORC1 in response to anabolic stimuli and outlines the factors that distinguish the periphery of the cell as a highly notable region of skeletal muscle for the induction of *** research should seek to further explore the nutrient-induced activation of mTORC1 at the periphery of skeletal muscle fibers.

关键词： Skeletal muscle mTOR Periphery Muscle protein synthesis Hypertrophy Translation

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Teaching Pupils to Cook ＂Will Tackle Obesity＂

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英语画刊（高三·社会综合版） 2009年第1期 28-29页

作者： Sarah cassidy

在英国，每个11岁的孩子都将会收到一本免费的食谱书。政府想通过这种方式鼓励孩子们自己学会做菜。以解决肥胖问题。

关键词：高中英语教学翻译方法教学方法

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Neuromyelitis optica spectrum disorders and anti-myelin oligodendrocyte glycoprotein positive optic neuropathies

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International Journal of Ophthalmology(English edition) 2022年第7期15卷 1095-1107页

作者： Patrick Murtagh Amy Coman Kirk Stephenson Maria Gaughan David Ryan Graeme McNeill Christopher McGuigan Lorraine cassidy Royal Victoria Eye and Ear Hospital Adelaide RoadDublin 2D02 XK51Republic of Ireland St Vincent’s University Hospital Elm ParkDublin 4D04 N2E0Republic of Ireland

AIM: To describe the clinical characteristics and treatments associated with antibody positive optic neuropathies including anti-myelin oligodendrocyte glycoprotein(MOG) and anti-aquaporin 4(AQP4), alongside diagnostic modalities, investigations, and outcomes. METHODS: A cross-sectional single-centre retrospective case series consisting of 16 patients including 12 antiMOG positive patients and 4 anti-AQP4 positive patients. Each of these patients had clinical signs and symptoms of optic neuritis and consisted of all patients who had a positive blood antibody result in our centre. Clinical findings including presence of a relative afferent pupillary defect, colour vision and disc assessment were recorded. Structured clinical exam and multimodal imaging was undertaken sequentially on each. Optical coherence tomography(OCT) scanning was preformed to examine the correlation between ganglion cell layer(GCL) thickness and visual acuity(VA) at presentation and as a determinant of final visual outcome in both groups. Initial and long-term treatment is also summarised. RESULTS: A total of 16 patients were included in the study consisting of 12 anti-MOG and 4 anti-AQP4 positive patients. Nine of the 16 patients were female and the average age of onset was 29.2 y in the MOG group and 42 y in the AQP4 group. There was no statistically significant correlation(Pearson correlation) between GCL thickness and presenting and final VA [r(10)=0.081, P=0.08 and r(10)=0.089, P=0.34 respectively]. The same statistical analysis was performed for the correlation between retinal nerve fibre layer(RNFL) and VA and similar outcomes wereobserved [r(10)=0.04, P=0.22 and r(10)=0.09, P=0.04]. No correlation was seen for initial RNFL thickness and final visual outcome in this group either [r(2)=0.19, P=0.38]. Visual field testing and radiological findings for each group are described. CONCLUSION: No correlation between initial VA or RNFL and final visual outcome is identified. A broad range of visu

关键词： neuromyelitis anti-myelin oligodendrocyte glycoprotein antibody anti-aquaporin 4

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Failure mechanisms of a spudcan penetrating next to an existing footprint

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Theoretical & Applied Mechanics Letters 2015年第2期5卷 64-68页

作者： Vickie Kong Mark J.cassidy Christophe Gaudin Fugro-Advanced Geomechanics Centre for Offshore Foundation Systems and ARC CoE for Geotechnical Science and Engineering University of Western Australia

Reinstallation of mobile jack-up rigs next to existing footprints is a problematic operation because the spudcan located near the footprints is subjected to eccentric and/or inclined loading conditions. Geotech- nical centrifuge studies have measured these loads for combinations of changing footprint geometry, footprint soil properties and the offset of the reinstallation from the footprint centre. These tests have been of full model spudcans in order to accurately measure the combined loads developed. They have not provided information on the mechanisms of failure occurring during this complex installation. Ob- servations from a visualisation test, where a half spudcan is penetrated against a transparent window in a geotechnical centrifuge, are reported in this paper. The mechanisms of failure at different stages during the nenetrntirm are nr^nted

关键词： Jack-up Footprint Combined loading Spudcan Offshore geotechnics

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