检索结果-南通市图书馆

Role of thermal ablation in the management of colorectal liver metastasis

Hepatobiliary Surgery and Nutrition 2020年第1期9卷 49-58页

作者： Hideo takahashi Eren Berber Department of Surgical Oncology Roswell Park Comprehensive Cancer CenterBuffaloNYUSA Department of Endocrine Surgery Cleveland ClinicClevelandOHUSA

With a recent randomized prospective trial revealing that thermal ablative therapy as local tumor control improved overall survival (OS) in patients with unresectable colorectal cancer liver metastases (CRLM), thermal ablation continues to remain as an important treatment option in this patient population. Our aim of this article is to review the current role of the ablative therapy in the management of CRLM patients. Main indications for thermal ablation include (Ⅰ) unresectable liver lesions;(Ⅱ) in combination with hepatectomy;(Ⅲ) in patients with significant medical comorbidities or poor performance status (PS);(Ⅳ) a small (<3 cm) solitary lesion, which would otherwise necessitate a major liver resection;and (Ⅴ) patient preference. There are several approaches and modalities for ablative therapy, including open, percutaneous, and laparoscopic approaches, as well as radiofrequency ablation (RFA) and microwave ablation (MWA). Each approach and ablation modality have its own pros and cons. Percutaneous and laparoscopic approaches are preferred due to minimally invasive nature, yet laparoscopic approach has more benefits from thorough intraoperative ultrasound (US) exam as well as complete peritoneal staging with laparoscopy. Similarly, whereas high local tumor failure rate has been a major concern with RFA, MWA or microwave thermosphere ablation (MTA) have demonstrated significantly improved local tumor control due to homogenous tissue heating, ability to reach higher tissue temperatures, and less susceptible to the "heat-sink" effect. Although liver resection is the standard of care for CRLM, there have been some retrospective studies demonstrating similar oncological outcome between ablative therapy and surgical resection in very selected populations with small (<3 cm) solitary CRLM. Lastly, ablative therapy and liver resection should not be mutually exclusive, especially in the management of bilobar liver metastases. Concomitant ablative therapy with hepatectomy

关键词： Thermal ablation radiofrequency ablation (RFA) microwave ablation (MWA) colorectal cancer livermetastasis (CRLM)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

From Darkness to Light: A Student’s Journey from Illness to Her True Passion

引用

Chinese Medicine and Culture 2018年第1期1卷 37-39页

作者： Tiffany takahashi Augusta University GAUSA

Yin and yang are the dark-bright,polar opposites that cannot exist without each *** like Rachel Clay’s passion for Chinese language and culture wouldn’t exist if it weren’t for the pain she endured.

关键词： Illness true passion yin and yang

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Axial charges of N(1535) and N(1650) in two-flavor lattice QCD

引用

Chinese Physics C 2009年第12期33卷 1233-1237页

作者： Toru T. takahashi Teiji Kunihiro Yukawa Institute for Theoretical Physics Kyoto University Kyoto 606-8502 Japan Department of Physics Kyoto University Kyoto 606-8502 Japan

We show the lattice QCD results on the axial charge gAN＊-N＊ of negative parity nucleon resonances, N＊（1535） and N＊（1650）, which are key clues to the chiral structure in baryon sector. The measurements are performed with up and down dynamical quarks employing the renormalization-group improved gauge action at β=1.95 and the O（a） improved clover quark action with the hopping parameters, κ=0.1375, 0.1390 and 0.1400. In order to properly separate signals of N＊（1535） and N＊（1650）, we construct 2 × 2 correlation matrices and diagonalize them. Wraparound contributions in the correlator, which can be another source of signal contaminations, are eliminated by imposing the Dirichlet boundary condition in the temporal direction. We find that the axial charge of N＊（1535） takes small values as gAN＊N＊-O（0.1）, whereas that of N＊（1650） is about 0.5, which is found independent of quark masses and consistent with the predictions by the naive nonrelativistic quark model.

关键词： axial charge chiral symmetry negative parity nucleon

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Experimental study on the in-plane thermal conductivity of Au nanofilms

引用

Progress in Natural Science:Materials International 2007年第2期17卷 212-216页

作者： takahashi Koji IKUTA Tatsuya FUJII Motoo Graduate School of Engineering Kyushu UniversityFukuoka 812-8581Japan Institute for Materials Chemistry and Engineering Kyushu UniversityKasuga 816-8580Japan

The in-plane thermal conductivity of Au nanofilms with thickness of 23 nm, which are fabricated by the electron beam-physical vapor deposition method and a suspension technology, is experimentally measured at 80-300 K by a one-dimensional steady-state electrical heating method. Strong size effects are found on the measured nanofilm thermal conductivity. The Au nanofilm in-plane thermal conductivity is much less than that of the bulk material. With the increasing temperature, the nanofilm thermal conductivity increases. This is opposite to the temperature dependence of the bulk property. The Lorenz number of the Au nanofilms is about three times larger than the bulk value and decreases with the increasing temperature, which indicates the invalidity of the Wiedemann-Franz law for metallic nanofilms.

关键词： nanofilm in-plane thermal conductivity size effect Wiedemann-Franz law.

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Molecular Mechanisms Contributing to Resistance to Tyrosine Kinase-Targeted Therapy for Non-Small Cell Lung Cancer

引用

Clinical oncology and cancer researeh 2012年第1期9卷 18-22页

作者： Fariz Nurwidya Akiko Murakami Fumiyuki takahashi Kazuhisa takahashi Department of Respiratory Medicine Juntendo University School of Medicine

One of the most important pathways in non-small cell lung cancer(NSCLC) is the epidermal growth factor receptor(EGFR) pathway. This pathway affects several crucial processes in tumor development and progression,including tumor cell proliferation,apoptosis regulation,angiogenesis,and metastatic *** EGFR is currently being intensely *** are witnessing the development of a number of potential molecular-inhibiting treatments for application in clinical *** the last decade,the tyrosine kinase(TK) domain of the EGFR was identified in NSCLC patients,and it has responded very well with a dramatic clinical improvement to TK inhibitors such are gefitinib and ***,there were primary and/or secondary resistance to these treatments,as shown by clinical *** molecular biology studies provided some explanations for the drug resistance *** molecular mechanisms of resistance need to be *** in-depth understanding of these targeted-therapy resistance may help us explore new strategies for overcoming or reversing the resistance to these inhibitors for the future of NSCLC treatment.

关键词： carcinoma non-small-cell lung mutation drug resistance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fluid-induced high-temperature metasomatism at Rundv?gshetta in the Lützow-Holm Complex, East Antarctica: Implications for the role of brine during granulite formation

引用

Geoscience Frontiers 2018年第5期9卷 1309-1323页

作者： Kazuki takahashi Toshiaki Tsunogae Emmanuel Nwachukwu Ugwuonah Graduate School of Life and Environmental Sciences University of TsukubaIbaraki 305-8572Japan Department of Geology University of JohannesburgAuckland Park 2006South Africa Department of Geology Chukwuemeka Odumegwu Ojukwu UniversityUliNigeria

We report new petrological, phase equilibria modeling, and fluid inclusion data for pelitic and mafic granulites from Rundv?gshetta in the highest-grade region of the Neoproterozoic Lützow-Holm Complex(LHC),East Antarctica, and provide unequivocal evidence for fluid-rock interaction and high-temperature metasomatism in the presence of brine fluid. The studied locality is composed dominantly of well-foliated pelitic granulite(K-feldspar+quartz+sillimanite+garnet+ilmenite) with foliation-parallel bands and/or layers of mafic granulite(plagioclase+orthopyroxene+garnet+ilmenite+quartz+biotite). The boundary between the two lithologies is defined by thin(about 1 -20 cm in thick) garnet-rich layers with a common mineral assemblage of garnet+plagioclase+quartz+ilmenite+biotite ? orthopyroxene. Systematic increase of grossular and decrease of pyrope contents in garnet as well as decreasing Mg/(Fe+Mg) ratio of biotite from the pelitic granulite to garnet-rich rock and mafic granulite suggest that the garnet-rich layer was formed by metasomatic interaction between the two granulite lithologies. Phase equilibria modeling in the system NCKFMASHTO demonstrates that the metasomatism took place at 850 -860℃, which is slightly lower than the peak metamorphism of this region, and the modal abundance of garnet is the highest along the metapeliteemetabasite boundary(up to 40%), which is consistent with the field and thin section observations. The occurrence of brine(7.0 -10.9 wt.% Na Cleqfor ice melting or 25.1 -25.5 wt.% NaC leqfor hydrohalite melting) fluid inclusions as a primary phase trapped within plagioclase in the garnet-rich layer and the occurrence of Cl-rich biotite(Cl = 0.22 -0.60 wt.%) in the metasomatic rock compared to that in pelitic(0.15 -0.24 wt.%) and mafic(0.06-0.13 wt.%) granulites suggest infiltration of brine fluid could have given rise to the high-temperature metasomatism. The fluid might have been derived from external sources possibly related to the formation

关键词： High-temperature metasomatism Brine Phase equilibrium modeling Fluid inclusion Gondwana Lützow-Holm Complex

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Lipophilic extractives of the inner and outer barks from six different Pinus species grown in Indonesia

引用

Journal of Forestry Research 2018年第5期29卷 1329-1336页

作者： Masendra Tatsuya Ashitani Koetsu takahashi Ganis Lukmandaru Department of Forest Product Technology Faculty of ForestryUniversitas Gadjah Mada Faculty of Agriculture Yamagata University

The chemical compositions of the dichloromethane extracts of inner and outer barks from six Pinus species（***,***,***,***,***,and ***） grown in Indonesia were investigated by GC and GC–***,the amounts of extractive contents were higher in the inner bark than in the outer bark except for *** acids,monoterpenes,sesquiterpenes,resin acids,triterpenoids,and steroids were detected and *** and outer barks differed not only in content of these compounds but also in their *** acids and alcohols were the major classes of lipophilic compounds in the outer bark of ***, ***,and *** and triterpenoids were the dominant compounds identified in the inner bark of ***,***,and *** acids were the most abundant group in the inner bark of *** whereas monoterpenes and sesquiterpenes were recorded in minor quantities in both bark layers of all species.

关键词： Bark extractive Lipophilic Inner bark Outer bark Pinus spp

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Structure and Bonding in Some Gd(Ⅲ) Metal Complexes Studied by Three-Dimensional X-Ray Analysis and ^(155)Gd Mssbauer Spectroscopy

引用

Journal of Rare Earths 2007年第6期25卷 647-653页

作者：王军虎 takahashi Masashi Kitazawa Takafumi Takeda Masuo Dalian Institute of Chemical Physics Chinese Academy of Sciences Department of Chemistry Faculty of Science Toho University 2-2-1 Miyama Funabashi Chiba 274-8510 Japan

Some functional lanthanide metal complexes, such as acetylacetonato complexes, ethylenediaminetetraacetato complexes, were successfully applied for diagnostic technique. The authors are interested in investigating the structure and bonding in lanthanide and actinide metal complexes using 166Er, t55Gd, and 237Np Mtissbauer spectroscopies in connection with single-crystal and/or powder X-ray diffraction, making clear the differences on their structures as well as the differences in the participation of 4f and 5f orbitals in the chemical bonds. In this article, the crystal structures of two novel Gd（Ⅲ） acetylacetonato complexes, Gd（pta）3 · 2H2O （pta = 1,1,1 -trifluoro-5,5-dimethy 1-2,4-hexanedione） and Gd（bfa）3 · 2H2O （bfa = 1, 1, 1 -trifluoro-4-phenyl-2-4-butanedione） were reported. Though both of them were dihydrate and had distorted square antiprismatical structure, Gd（pta）3 · 2H2O crystallizes in the P 2 1/n （#14） monoclinic space group and its lattice parameters are a = 1.4141（6） nm, b = 1.0708（3） nm, c =2.2344（4） nm, β =952.4（2）°, and Gd（bfa）3· 2H2O crystallizes in P 212121 orthorhombic space group and its lattice parameters were a = 1.322 （1） nm, b = 2.295 （1） nm, c = 1. 0786（8） nm. In the meantime, the authors had finished a systematic investigation on the ^155Gd Mossbauer isomer shift （δ） of various Gd（Ⅲ） metal complexes having a different coordination number （C.N.） and different ratios coordinating oxygen to nitrogen. A tendency for the 6 value to decrease with an increase in the C.N, and the number of the nitrogen atom coordinating to Gd was confirmed. This indicated that the Gd-O and/or Gd-N bond in the investigated Gd（Ⅲ） metal complexes had a small covalent contribution, which was possible to be deduced from the O and/or N atoms of the lisands donating electrons to 6s, 5d, and 4f orbitals of Gd.

关键词： Gd(Ⅲ) metal complex crystal structure bonding ^155Gd Mossbauer spectroscopy three-dimensional X-ray analysis covalent contribution rare earths

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Different effects of grain boundary scattering on charge and heat transport in polycrystalline platinum and gold nanofilms

引用

Chinese Physics B 2009年第5期18卷 2035-2040页

作者：马维刚王海东张兴 takahashi Koji Key Laboratory for Thermal Science and Power Engineering of Ministry of Education Department of Engineering MechanicsTsinghua University Graduate School of Engineering Kyushu University

The in-plane electrical and thermal conductivities of several polycrystalline platinum and gold nanofilms with different thicknesses are measured in a temperature range between the boiling point of liquid nitrogen （77K） and room temperature by using the direct current heating method. The result shows that both the electrical and thermal conductivities of the nanofilms reduce greatly compared with their corresponding bulk values. However, the electrical conductivity drop is considerably greater than the thermal conductivity drop, which indicates that the influence of the internal grain boundary on heat transport is different from that of charge transport, hence leading to the violation of the Wiedemann-Franz law. We build an electron relaxation model based on Matthiessen＇s rule to analyse the thermal conductivity and employ the Mayadas ＆ Shatzkes theory to analyse the electrical conductivity. Moreover, a modified Wiedemann-Franz law is provided in this paper, the obtained results from which are in good agreement with the experimental data.

关键词： polycrystalline nanofilm grain boundary scattering thermal and electrical conductivities Wiedemann-Franz law

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Foreword for the special issue of the 7th China-Japan bilateral symposium on high temperature strength of materials

引用

Acta Metallurgica Sinica(English Letters) 2011年第2期24卷 I0001-I0002页

作者： Shan-Tung TU Yukio takahashi East China University of Science and Technology Central Research Institute of Electric Power Industry

The 7th China-Japan Bilateral Symposium on High Temperature Strength of Mate- rials was held at Dalian, China, during the period August 23-27, 2010. The symposium was co-organized by the High Temperature Strength and Materials Committee, the So- ciety of Materials, Chinese Mechanical Engineering Society and the Committee on High Temperature Strength of Materials, the Society of Materials Science Japan.

关键词： 7th China-Japan bilateral symposium on high temperature strength of materials lecture Japan friendship

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：