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In vivo and ex vivo confocal endomicroscopy of pancreatic cystic lesions: A prospective study

World j.urnal of Gastroenterology 2017年第18期23卷 3338-3348页

作者： Somashekar G Krishna Rohan M Modi Amrit K Kamboj.Benj.min j.Swanson Phil A hart Mary E Dillhoff Andrei Manilchuk Carl R Schmidt Darwin L Conwell Division of Gastroenterology Hepatology and NutritionThe Ohio State University Wexner Medical Center Department of Internal Medicine The Ohio State University Wexner Medical Center College of Medicine The Ohio State University Wexner Medical Center Department of Pathology The Ohio State University Wexner Medical Center Division of Surgical Oncology The Ohio State University Wexner Medical Center Deparment of General Surgery The Ohio State University Wexner Medical Center

To investigate the reproducibility of the in vivo endoscopic ultrasound (EUS) - guided needle based confocal endomicroscopy (nCLE) image patterns in an ex vivo setting and compare these to surgical histopathology for characterizing pancreatic cystic lesions (PCLs).METHODSIn a prospective study evaluating EUS-nCLE for evaluation of PCLs, 10 subj.cts underwent an in vivo nCLE (AQ-Flex nCLE miniprobe; Cellvizio, MaunaKea, Paris, France) during EUS and ex vivo probe based CLE (pCLE) of the PCL (Gastroflex ultrahigh definition probe, Cellvizio) after surgical resection. Biopsies were obtained from ex vivo CLE-imaged areas for comparative histopathology. All subj.cts received intravenous fluorescein prior to EUS and pancreatic surgery for in vivo and ex vivo CLE imaging *** total of 10 subj.cts (mean age 53 ± 12 years; 5 female) with a mean PCL size of 34.8 ± 14.3 mm were enrolled. Surgical histopathology confirmed 2 intraductal papillary mucinous neoplasms (IPMNs), 3 mucinous cystic neoplasms (MCNs), 2 cystic neuroendocrine tumors (cystic-NETs), 1 serous cystadenoma (SCA), and 2 squamous lined PCLs. Characteristic in vivo nCLE image patterns included papillary proj.ctions for IPMNs, horizon-type epithelial bands for MCNs, nests and trabeculae of cells for cystic-NETs, and a “fern pattern” of vascularity for SCA. Identical image patterns were observed during ex vivo pCLE imaging of the surgically resected PCLs. Both in vivo and ex vivo CLE imaging findings correlated with surgical *** vivo nCLE patterns are reproducible in ex vivo pCLE for all maj.r neoplastic PCLs. These findings add further support the application of EUS-nCLE as an imaging biomarker in the diagnosis of PCLs.

关键词： Confocal laser endomicroscopy Serous cystadenoma Pancreatic neuroendocrine tumor Intraductal papillary mucinous neoplasm Pancreatic cystic neoplasm

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ABDX阀的性能介绍

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国外铁道车辆 1989年第3期 10-15页

作者： j.E.hart 葛培昌

ABDXN是美国威斯汀豪斯公司在ABDW阀的基础上研制成功的货车新型控制阀。本文在概括地介绍了ABDX阀的结构特点和性能比较之后,得出结论认为,该阀与ABDW阀等相比,简化了结构,提高了常用和紧急制动性能,同时改善了防漏的可靠性和防止意外... 详细信息

ABDXN是美国威斯汀豪斯公司在ABDW阀的基础上研制成功的货车新型控制阀。本文在概括地介绍了ABDX阀的结构特点和性能比较之后,得出结论认为,该阀与ABDW阀等相比,简化了结构,提高了常用和紧急制动性能,同时改善了防漏的可靠性和防止意外紧急制动的稳定性。

关键词：紧急制动 ABDX MPa 紧急部制动管制动缸常用制动

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Libby Amphibole Contamination in Tree Bark Surrounding Historical Vermiculite Processing Facilities

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j.urnal of Environmental Protection 2011年第8期2卷 1062-1068页

作者： Mohamed I. Elashheb Terry M. Spear j.lie F. hart j.mes S. Webber Tony j. Ward 不详

Over a 70-year period, a mine near Libby, MT supplied nearly 80% of the world’s vermiculite. Raw vermiculite, which was contaminated with naturally occurring amphibole in veins throughout the deposit, was shipped to processing sites throughout the United States for exfoliation. In this pilot study, tree bark samples were collected near processing facilities in Spokane, WA, Santa Ana, CA, Newark, CA, and Phoenix, AZ in an effort to determine if areas surrounding these facilities are today contaminated with Libby amphibole asbestos (AA). From areas surrounding each of the four historical processing sites, Libby AA was detected in a subset of the bark samples. At the Santa Ana, Newark and Phoenix facilities, actinolite-tremolite and other high Fe Ca-bearing amphibole were also measured from the bark samples. In addition, chrysotile was frequently measured in samples collected from each of the sites. From the results of this pilot study, it is evident that tree bark can serve as reservoirs of asbestos, and indicators of past and current contamination. These data also suggest that areas outside of these historical processing facilities may today have some level of existing contamination resulting from the operation of these facilities.

关键词： Vermiculite Asbestos Amphibole Libby Exfoliation Tree Bark

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Laser additive manufacturing for infrastructure repair:A case study of a deteriorated steel bridge beam

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j.urnal of Materials Science & Technology 2023年第23期154卷 149-158页

作者： Shengbiao Zhang Peij.n Hou j.yun Kang Tianyi Li Shahryar Mooraj.Yang Ren Catherine H.Chen A.j.hn hart Simos Gerasimidis Wen Chen Department of Mechanical and Industrial Engineering University of Massachusetts Amherst MA 01003 USA Department of Civil and Environmental Engineering University of Massachusetts Amherst MA 01003 SA Department of Materials Science and Engineering Massachusetts Institute of Technology Cambridge MA 02139 USA X-ray Science Division Argonne National Laboratory Lemont IL 60439 USA Massachusetts Department of Transportation Boston MA 02116 USA Department of Mechanical Engineering Massachusetts Institute of Technology Cambridge MA 02139 USA Department of Physics City University of Hong Kong Kowloon Hong Kong China

As our transportation infrastructure ages,its deterioration is becoming a growing *** and effective methods for repair can reduce the need for time-and cost-intensive replacement of structures such as roadway *** this work,laser-based additive manufacturing(AM)was developed for the repair of damaged beams in steel bridges.A corroded structural beam of low-carbon A36 steel was selected for this case study and 316L stainless steel was used for repair due to its excellent mechanical properties and corrosion *** repair experiments were performed on specimens extracted from the beam,and prepared with various groove shapes(Rectangular,Trapezoidal,and U-shaped).More in-depth parametric and microstructural studies were carried out with a series of U-shaped specimens repaired with the linear laser input energy varied from 19.5 to 30.0 j.mm–*** tensile properties of the repaired specimens and interface structures were also investigated in *** was found that the repaired specimens had a slightly higher tensile strength despite a reduction in tensile elongation compared to the A36 steel base *** influence of interfacial microstructure and heterogeneity on the mechanical properties of the repaired specimens was *** work suggests the promising potential to employ AM for structural repair and provides fundamental insights into processing-structure-property relationships in laser AM-repaired materials.

关键词： Additive manufacturing Structural repair Mechanical properties Transportation infrastructure Dissimilar j.int

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世界鱼类产量的增长、组成和利用

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福建水产 1985年第3期7卷 58-63页

作者： Tong j. Pitcher Paul j. B. hart 朱耀光

1955年至1970年的15年间，全世界各国捕获的鱼类总产量增长了一倍多，9,3，0007／吨增至7，000万吨(图1)。1970年以来产量变动于6，500万吨到7，350万吨之间。产量低于通常水平主要是秘鲁鳀鱼渔业几乎完全崩溃的结果。过去6年为人类直... 详细信息

1955年至1970年的15年间，全世界各国捕获的鱼类总产量增长了一倍多，9,3，0007／吨增至7，000万吨(图1)。1970年以来产量变动于6，500万吨到7，350万吨之间。产量低于通常水平主要是秘鲁鳀鱼渔业几乎完全崩溃的结果。过去6年为人类直接消费用的鱼类产量继续增长．研究这种趋势的原因是有教益的。

关键词：世界鱼类产量增长产量组成利用远洋捕捞产量

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Management of metal-on-metal hip implant patients: Who,when and how to revise?

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World j.urnal of Orthopedics 2016年第5期7卷 272-279页

作者： Reshid Berber j.hn A Skinner Alister j.hart j.int Reconstruction Unit Institute of Orthopaedics and Musculoskeletal Sciences Royal National Orthopaedic Hospital

The debate on how best to manage patients with metal-on-metal(MOM) hip implants continues. With over 1 million patients affected worldwide, the impact is far reaching. The maj.rity of the aggressive failures of MOM hip implants have been dealt with by revision hip surgery, leaving patients with a much more indolent pattern of failure of devices that have been in situ for more than 10 years. The longer-term outcome for such patients remains unknown, and much debate exists on how best to manage these patients. Regulatory guidance is available but remains open to interpretation due to the lack of current evidence and long-term studies. Metal ion thresholds for concern have been suggested at 7 ppb for hip resurfacing arthroplasty and below this level for large diameter total hip arthroplasties. Soft tissue changes including pseudotumours and muscle atrophy have been shown to progress, but this is not consistent. New advanced imaging techniques are helping to diagnose complications with metal hips and the reasons for failure, however these are not widely available. This has led to some centres to tackle difficult cases through multidisciplinary collaboration, for both surgical management decisions and also follow-up decisions. We summarise current evidence and consider who is at risk, when revision should be undertaken and how patients should be managed.

关键词： Metal on metal hip Management Multidisciplinary Revision Decision

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Treatment and prevention of epilepsy in onchocerciasis-endemic areas is urgently needed

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Infectious Diseases of Poverty 2024年第1期13卷 85-89页

作者： Robert Colebunders j.seph Nelson Siewe Fodj. Olivia Kamoen Luis-j.rge Amaral Amber Hadermann Chiara Trevisan Mark j.Taylor j.lia Gauglitz Achim Hoerauf Yasuaki Sato Katj. Polman Maria-Gloria Basanez Dan Bhwana Thomson Lakwo Gasim Abd-Elfarag Sebastien D.Pion Global Health Institute University of AntwerpAntwerpBelgium Department of Neurology Heilig Hart ZiekenhuisLierBelgium Department of Public Health Institute of Tropical MedicineAntwerpBelgium Liverpool School of Tropical Medicine LiverpoolUK Department of Computer Science University of AntwerpAntwerpBelgium Institute of Medical Microbiology Immunology and ParasitologyUniversity Hospital BonnBonnGermany German Center for Infection Research(DZIF) Partner Site Bonn-CologneBonnGermany School of Global Humanities and Social Sciences Nagasaki UniversityNagasakiJapan MRC Centre for Global Infectious Disease Analysis and London Centre for Neglected TropicalDisease Research Department of Infectious Disease EpidemiologySchool of Public HealthImperial College LondonLondonUK National Institute for Medical Research TangaTanzania Vector Control Division Ministry of HealthKampalaUganda School of Public Health University of JubaJubaSouth Sudan Access for Humanity JubaSouth Sudan French National Research Institute for Sustainable Development MontpellierFrance

Background There is increasing epidemiological evidence supporting the association between onchocerciasis and seizures, reinforcing the concept of onchocerciasis-associated epilepsy (OAE). The aim of this paper is to provide an update on the new knowledge about OAE and to propose recommendations to the World Health Organization how to address this public health *** text During the 2nd International Workshop on OAE held on 19-21 September, 2023, in Antwerp, Belgium, participants recognised OAE as a substantial yet neglected public health problem, particularly in areas of sub-Saharan Africa where onchocerciasis remains hyperendemic. Evidence from prospective population-based studies suggest that strengthening onchocerciasis elimination efforts leads to a significant reduction of OAE incidence. There is a need to validate an OAE case definition to estimate the burden of disease and identify onchocerciasis-endemic areas requiring intensification of onchocerciasis elimination programmes and integration of epilepsy care. It is expected that raising awareness about OAE will boost the population uptake of ivermectin. The implementation of a community-based epilepsy treatment programme offering free anti-seizure medications (ASMs) has shown high effectiveness in reducing the frequency of seizures and improving the overall quality of life of people with *** To reduce OAE burden, enhanced collaboration between onchocerciasis and mental health programmes at community, national, and international levels is required. Urgent efforts are needed to ensure the uninterrupted provision of free ASMs in onchocerciasis-endemic areas. Furthermore, OAE should be included in the quantification of the onchocerciasis disease burden.

关键词： Onchocerciasis Morbidity Burden of disease Prevention Ivermectin Epilepsy Nodding syndrome Treatment Children Policy

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根据加拿大中部花粉记录定量重建植被演变历史的研究

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中国科学（D辑） 2008年第11期38卷 1396-1403页

作者：于革 hart Catherine Mary Vetter David Sauchyn 湖泊与环境国家重点实验室中国科学院南京地理与湖泊研究所南京210008 Prairie Adaptation Research Collaborative SKS4S 7J7Canada Department of Biology University of ReginaS4S 0A2Canada Department of Geography University of ReginaS4S 0A2Canada

根据加拿大中部高精度湖泊钻孔的花粉数据,介绍花粉型组合生态系植被单元和现代类比法模拟古植被的研究方法,报告拟合现代植被和验证生态系区后应用在沉积花粉中、重建过去1000年以来古植被的主要结果.该研究表明,在115°～95°W和40°... 详细信息

根据加拿大中部高精度湖泊钻孔的花粉数据,介绍花粉型组合生态系植被单元和现代类比法模拟古植被的研究方法,报告拟合现代植被和验证生态系区后应用在沉积花粉中、重建过去1000年以来古植被的主要结果.该研究表明,在115°～95°W和40°～60°N的北美中部,花粉模拟的现代植被中的北方林型最佳类比率81%,稀树草地型72%,草原和稀树草地型94%,与北美Ⅱ生态系植被分布基本吻合.钻孔沉积花粉的植被模拟反映了过去1000年北美中部经历了中世纪暖期,具有温暖而干旱的气候;小冰期前期寒冷而湿润,后期寒冷而干旱;20世纪具有显著的增温和转干特征.该项研究可为中国学者采用花粉记录探索过去1000年以来植被变化,尤其是在具有特征气候区域、10～100年时间精度的气候植被研究提供良好的研究途径和科学依据.

关键词：沉积花粉表土花粉现代类比法生态系区古植被过去1000年

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所有权的成本和收益:一个纵向和横向一体化理论

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经济社会体制比较 2017年第1期 14-30页

作者：桑福德.格罗斯曼奥利弗.哈特阮睿美国QFS资产管理公司哈佛大学中国人民大学经济学院

文章提出有成本的契约理论,强调契约权利有两种类型:具体权利和剩余权利。当在契约中列出与资产有关的所有具体权利的成本很高时,最好让其中一方从另一方购买所有的剩余权利。取得所有权就是购买这些剩余权利。当剩余权利被一方购买以后... 详细信息

文章提出有成本的契约理论,强调契约权利有两种类型:具体权利和剩余权利。当在契约中列出与资产有关的所有具体权利的成本很高时,最好让其中一方从另一方购买所有的剩余权利。取得所有权就是购买这些剩余权利。当剩余权利被一方购买以后,另一方就失去了剩余权利,这不可避免地造成了扭曲。而当企业1取得控制权增加其管理的生产力大于企业2失去控制降低其管理的生产力时,企业1就会购买企业2。

关键词：所有权不完全契约理论剩余控制权

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渔业生态学

渔业生态学

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1988年

作者： T.j.PITCHER P.j.B.hart 刘元春王明德译

来源：汇雅图书（南通市图书馆... 评论

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