检索结果-南通市图书馆

Peptide drugs: a new direction in cancer immunotherapy

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cancer Biology & Medicine 2024年第3期21卷 198-203页

作者： Xinghua sui Xiaoshuang Niu Xiuman Zhou Yanfeng Gao School of Pharmaceutical Sciences(Shenzhen) Shenzhen Campus of Sun Yat-sen UniversityShenzhen 518107China

Cancer immunotherapy has emerged as a promising approach in cancer treatment and is considered a major advancement after surgical interventions, radiotherapy, chemotherapy, and targeted therapy. The clinical use of im... 详细信息

关键词： drugs immunotherapy cancer

Surface engineering with ionic polymers on membranes for boron removal

在线全文

学校读者我要写书评

暂无评论

Frontiers of Chemical Science and Engineering 2024年第5期18卷 61-69页

作者： Xiting Zhang Chenyi Fang J Paul Chen sui Zhang Department of Chemical and Biomolecular Engineering National University of SingaporeSingapore 117576Singapore Department of Civil and Environmental Engineering National University of SingaporeSingapore 119260Singapore College of Chemistry and Environmental Engineering Shenzhen UniversityShenzhen 518060China

Removal of boric acid from seawater and wastewater using reverse osmosis membrane technologies is imperative and yet remains inadequately addressed by current commercial membranes.Existing research efforts performed post-modification of reverse osmosis membranes to enhance boron rejection,which is usually accompanied by substantial sacrifice in water permeability.This study delves into the surface engineering of low-pressure reverse osmosis membranes,aiming to elevate boron removal efficiency while maintaining optimal salt rejection and water permeability.Membranes were modified by the self-polymerization and co-deposition of dopamine and polystyrene sulfonate at varying ratios and concentrations.The surfaces became smoother and more hydrophilic after modification.The optimum membrane exhibited a water permeability of 9.2±0.1 L·m^(-2)·h^(-1)·bar^(-1),NaCl rejection of 95.8%±0.3%,and boron rejection of 49.7%±0.1%and 99.6%±0.3%at neutral and alkaline pH,respectively.The water permeability is reduced by less than 15%,while the boron rejection is 3.7 times higher compared to the blank membrane.This research provides a promising avenue for enhancing boron removal in reverse osmosis membranes and addressing water quality concerns in the desalination process.

关键词： membrane low-pressure reverse osmosis boron surface engineering

Characteristics of turbulent flow in 3-D pools in the presence of submerged rigid vegetation in channel bed

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Hydrodynamics 2024年第1期36卷 158-169页

作者： Kourosh Nosrati Hossein Afzalimehr Jueyi sui Hamid Reza Reisifar Natural Disasters Prevention Research Center Faculty of Civil EngineeringIran University of Science and TechnologyTehranIran School of Engineering University of Northern British ColumbiaPrince GeorgeCanada

In this study,the interaction between 3-D bedforms and submerged rigid vegetation has been investigated.Various laboratory experiments were conducted to study the distribution of flow velocity,Reynolds shear stress,turbulent kinetic energy,and skewness coefficients for a constant density of vegetation.Results showed that the velocity profile in the pool section deviates from those in the upstream section of the pool.It has been found that the dip parameter varied between 0.6H and 0.9H depending on various factors including bed roughness,vegetation distribution,and pool entrance/exit slopes.However,scattered vegetation in the pool and differences in slopes created non-uniform flow conditions.Also,in the wake region behind each vegetated element,flow velocity reduced significantly,and small-scale eddies are formed,causing increased perturbations.By decreasing the entrance slope and bed roughness,relatively uniform flow and weaker turbulence was resulted,but the random distribution of vegetated elements counteracted this balance and intensified turbulence.With the decrease in the pool entrance slope,the contribution of sweep event decreased and the contribution of ejection event increased.

关键词： Submerged rigid vegetation 3-D pool Reynolds shear stress skewness coefficients

What induced the trend shift of mixed-layer depths in the Antarctic Circumpolar Current region in the mid-1980s?

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Oceanologica Sinica 2024年第1期43卷 11-21页

作者： Shan Liu Jingzhi Su Huijun Wang Cuijuan sui Key Laboratory of Marine Hazards Forecasting National Marine Environmental Forecasting CenterMinistry of Natural ResourcesBeijing 100081China Center for Earth System Modeling and Prediction of CMA Beijing 100081China Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science&TechnologyNanjing 210044China Nansen-Zhu International Research Center Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China

An obvious trend shift in the annual mean and winter mixed layer depth(MLD)in the Antarctic Circumpolar Current(ACC)region was detected during the 1960–2021 period.Shallowing trends stopped in mid-1980s,followed by a period of weak trends.The MLD deepening trend difference between the two periods were mainly distributed in the western areas in the Drake Passage,the areas north to Victoria Land and Wilkes Land,and the central parts of the South Indian sector.The newly formed ocean current shear due to the meridional shift of the ACC flow axis between the two periods is the dominant driver for the MLD trends shift distributed in the western areas in the Drake Passage and the central parts of the South Indian sector.The saltier trends in the regions north to Victoria Land and Wilkes Land could be responsible for the strengthening mixing processes in this region.

关键词： mixed layer depth trend shift Antarctic Circumpolar Current(ACC) flow axis

Molecular mechanisms of stress resistance in sorghum: Implications for crop improvement strategies

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2024年第3期23卷 741-768页

作者： Hongxiang Zheng Yingying Dang Xianmin Diao Na sui Shandong Provincial Key Laboratory of Plant Stress/College of life Sciences Shandong Normal UniversityJinan 250014China Institute of Crop Sciences Chinese Academy of Agricultural SciencesBeijing 100081China

Abiotic stresses, such as drought, salt, extreme temperatures, and heavy metal pollution, are the main environmental factors that limit crop growth and yield. Sorghum, a C4 grass plant with high photosynthetic efficiency, can grow in adverse environmental conditions due to its excellent stress resistance characteristics. Therefore, unraveling the stress-resistance mechanism of sorghum could provide a theoretical basis for developing and cultivating various stress-resistant crops. This understanding could also help to create a conducive environment for using marginal soil in agriculture and ensuring food security. In this review, we discuss the adaptation mechanisms of sorghum under drought, salinity, temperature, and soil heavy metal stresses, the specific response to stress, the screening of sorghum-resistant germplasm, and the identification and functional analysis of the relevant genes and quantitative trait loci(QTL). In addition, we discuss the application potential of different stress-tolerant sorghum germplasms reported to date and emphasize the feasibility and potential use in developing and promoting highly stress-tolerant sorghum in marginal soil.

关键词： abiotic stress C4 plants QTL sorghum stress resistance yield stability

Non-equilibrium kinetic separation of thulium,yttrium and erbium on the surface of freely rising oil droplets

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第1期42卷 200-209,I0007页

作者： Na sui Shukai Miao Kaihui Cui Fancheng Meng Kun Huang School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing100083China Beijing Key Laboratory of Green Recovery and Extraction of Rare and Precious Metals University of Science and Technology BeijingBeijing100083China Key Laboratory of Green Process and Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing100190China

It is difficult to achieve selective separation and enrichment of different rare earths from high abundance yttrium ores efficiently only dependent on their discrepancy in thermodynamic properties.The present work suggests a new strategy based on non-equilibrium kinetic separation of Er and Tm on the surface of freely rising oil droplets to control the separation order of Y.It is revealed that the mutual separation of Er/Tm is significantly promoted with the separation coefficient of 2.89 during the non-equilibrium extraction with the addition of diethylenetriaminepentaacetic acid(DTPA).The extraction sequence of Tm,Er and Y can be controlled as Tm>Y>Er,thus Y can be selectively enriched during the process of separation of Er and Tm,Such a sequence is subject to the controllable dissociation rates of RE(Ⅲ)-DTPA complexes and extraction abilities of P507 with the three RE(Ⅲ)ions.The dissociation rate is dependent on the stabilities of RE(Ⅲ)-DTPA complexes and follows the sequence ofY(Ⅲ)—DTPA Er>Y to Tm>Y>Er.

关键词： DTPA Interface interaction Non-equilibrium kinetic separation Rare earths P507

Singlet oxygen-dominated peroxymonosulfate activation by layered crednerite for organic pollutants degradation in high salinity wastewater

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第1期135卷 86-96页

作者： Chengji sui Zixuan Nie Huan Liu Grzegorz Boczkaj Weizhen Liu Lingshuai Kong Jinhua Zhan Key Laboratory for Colloid&Interface Chemistry of Education Ministry Department of ChemistryShandong UniversityJinan 250100China School of Environment and Energy Guangdong Provincial Key Laboratory of Solid Wastes Pollution Control and RecyclingSouth China University of TechnologyGuangzhou 510006China Gdansk University of Technology Faculty of Civil and Environmental EngineeringDepartment of Sanitary EngineeringG.Narutowicza St.11/1280-233 GdanskPoland EkoTech Center Gdansk University of TechnologyG.Narutowicza St.11/1280-233 GdanskPoland

Advanced oxidation processes have been widely studied for organic pollutants treatment in water,but the degradation performance of radical-dominated pathway was severely inhibited by the side reactions between the anions and radicals,especially in high salinity conditions.Here,a singlet oxygen(^(1)O_(2))-dominated non-radical process was developed for organic pollutants degradation in high salinity wastewater,with layered crednerite(CuMnO_(2))as catalysts and peroxymonosulfate(PMS)as oxidant.Based on the experiments and density functional theory calculations,^(1)O_(2)was the dominating reactive species and the constructed Cu-O-Mn with electron-deficient Mn captured electron from PMS promoting the generation of^(1)O_(2).The rapid degradation of bisphenol A(BPA)was achieved by CuMnO_(2)/PMS system,which was 5-fold and 21-fold higher than that in Mn_(2)O_(3)/PMS system and Cu_(2)O/PMS system.The CuMnO_(2)/PMS system shown prominent BPA removal performance under high salinity conditions,prominent PMS utilization efficiency,outstanding total organic carbon removal rate,wide range of applicable pH and good stability.This work unveiled that the^(1)O_(2)-dominated non-radical process of CuMnO_(2)/PMS system overcame the inhibitory effect of anions in high salinity conditions,which provided a promising technique to remove organic pollutants from high saline wastewater.

关键词： Singlet oxygen Non-radical process High salinity Mixed metal oxides Wastewater treatment

Effect of Wave Nonlinearity on the Instantaneous Seabed Liquefaction

在线全文

学校读者我要写书评

暂无评论

China Ocean Engineering 2024年第1期38卷 93-103页

作者： WANG Zhao-jun sui Ti-ti ZHANG Chi PAN Jun-ning Key Laboratory of Port Waterway and Sedimentation Engineering of the Ministry of TransportNanjing Hydraulic Research InstituteNanjing 210024China Key Laboratory of Coastal Disaster and Protection(Hohai University) Ministry of EducationNanjing 210098China The National Key Laboratory of Water Disaster Prevention Nanjing 210098China

The nonlinear variation of wave is commonly seen in nearshore area,and the resulting seabed response and liquefaction are of high concern to coastal engineers.In this study,an analytical formula considering the nonlinear wave skewness and asymmetry is adopted to provide wave pressure on the seabed surface.The liquefaction depth attenuation coefficient and width growth coefficient are defined to quantitatively characterize the nonlinear effect of wave on seabed liquefaction.Based on the 2D full dynamic model of wave-induced seabed response,a detailed parametric study is carried out in order to evaluate the influence of the nonlinear variation of wave loadings on seabed liquefaction.Further,new empirical prediction formulas are proposed to fast predict the maximum liquefaction under nonlinear wave.Results indicate that(1)Due to the influence of wave nonlinearity,the vertical transmission of negative pore water pressure in the seabed is hindered,and therefore,the amplitude decreases significantly.(2)In general,with the increase of wave nonlinearity,the liquefaction depth of seabed decreases gradually.Especially under asymmetric and skewed wave loading,the attenuation of maximum seabed liquefaction depth is the most significant among all the nonlinear wave conditions.However,highly skewed wave can cause the liquefaction depth of seabed greater than that under linear wave.(3)The asymmetry of wave pressure leads to the increase of liquefaction width,whereas the influence of skewedness is not significant.(4)Compared with the nonlinear waveform,seabed liquefaction is more sensitive to the variation of nonlinear degree of wave loading.

关键词： nonlinear wave seabed response seabed liquefaction numerical simulation liquefaction prediction

Impacts of Water-Sediment Regulation Scheme on Chromophoric Dissolved Organic Matter in the Lower Yellow River

在线全文

学校读者我要写书评

暂无评论

Journal of Ocean University of China 2024年第2期23卷 455-466页

作者： LIU Xiao JIANG Xueyan LIU Qian sui Juanjuan ZOU Li Key Laboratory of Marine Chemistry Theory and Technology of Ministry of Education Ocean University of ChinaQingdao 266100China College of Chemistry and Chemical Engineering Ocean University of ChinaQingdao 266100China School of Earth Sciences University of BristolBristolBS81RJUK North China Sea Environmental Monitoring Center State Oceanic AdministrationQingdao 266033China Key Laboratory of Ecological Prewarning Protection and Restoration of Bohai SeaMinistry of Natural ResourcesQingdao 266033China Key Laboratory of Marine Environment and Ecology of Ministry of Education Ocean University of ChinaQingdao 266100China College of Environmental Science and Engineering Ocean University of ChinaQingdao 266100China

As a river with more than 3000 reservoirs in its watershed,the Yellow River has been affected by dams not only on the sediment load,but also on the water quality.Water-sediment regulation scheme(WSRS),which has been carried out annually in the Yellow River since 2002,is a typical human activity affecting river water quality.Chromophoric dissolved organic matter(CDOM)in river is susceptible to changes in ecological and environmental conditions as well as human activities.Here,we report variations in dissolved organic carbon concentrations,compositions and sources of CDOM in time series samples in the lower Yellow River during WSRS.In addition,a parallel factor fluorescence analysis(PARAFAC)method is applied to identify different fluorescent components in water samples during WRSR,showing four major components including tryptophan-like component(C1),microbial humic-like component(C2),terrestrial humic-like component(C3)and tyrosine-like component(C4).In general,C1 increased after water regulation,while C2 and C3 increased after sediment regulation,indicating that the water and sediment released by the dam have different effects on CDOM compositions.Under the impacts of the dam,source of CDOM in the lower Yellow River is mainly autochthonous related to microbial activities,and is regulated by the terrestrial input during WSRS period.Sediment resuspension inhibits microbial activities and reduces the production of autochthonous CDOM.Overall,human activities especially WSRS,as exemplified here,significantly alter the quality and quantity of CDOM in the lower Yellow River,affecting CDOM dynamics and biogeochemical processes in the estuarine environment.

关键词： chromophoric dissolved organic matter(CDOM) water-sediment regulation scheme(WSRS) Yellow River optical properties